Antimicrobial Resistance in the Hospital Setting: Impact, Trends, and Infection Control Measures

2005 ◽  
Vol 25 (10 Part 2) ◽  
pp. 44S-54S ◽  
Author(s):  
Gary E. Stein
2006 ◽  
Vol 27 (6) ◽  
pp. 623-625 ◽  
Author(s):  
Ellen Bamberger ◽  
Orna Starets-Haham ◽  
David Greenberg ◽  
Argyro Karidis ◽  
Nurit Porat ◽  
...  

We report 4 cases involving the likely transmission of pertussis from parents to newborns in a hospital setting. The adoption of proper infection control measures and targeted screening of parents may reduce the potential for such transmission.


2001 ◽  
Vol 29 (Supplement) ◽  
pp. N128-N134 ◽  
Author(s):  
David K. Warren ◽  
Victoria J. Fraser

2020 ◽  
Vol 8 (9) ◽  
pp. 1378 ◽  
Author(s):  
Carlos L. Correa-Martínez ◽  
Vera Schwierzeck ◽  
Alexander Mellmann ◽  
Marc Hennies ◽  
Stefanie Kampmeier

During the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, healthcare systems worldwide have to prevent nosocomial SARS-CoV-2 transmission while maintaining duty of care. In our study, we characterize the transmission dynamic of SARS-CoV-2 in inpatients and healthcare workers (HCWs) at the University Hospital Münster (UHM) in northwest Germany. We identified 27 cases of healthcare-associated SARS-CoV-2 infections (4 inpatients and 23 HCWs) who had contact with patients and/or HCWs without the use of adequate PPE. The contacts of these index cases were followed up for SARS-CoV-2 infection after unprotected exposure and a quantitative measure of probability of becoming infected, the attack rate, was calculated. In addition, transmission was evaluated in the context of infection control measures established during the pandemic and we compared the epidemiological data of all index cases, including symptoms and Ct values of virology test results. The overall attack rate in the hospital setting was 1.3% (inpatients 0.9%, HCWs 1.6%). However, during an outbreak, the attack rate was 25.5% (inpatients 20.0%, HCWs 29.6%). For both scenarios, HCWs had a higher attack rate illustrating their role in healthcare-associated SARS-CoV-2 transmission. Taken together, our experiences demonstrate how infection control measures can minimize the transmission of SARS-CoV-2 in the healthcare setting.


PEDIATRICS ◽  
1996 ◽  
Vol 98 (5) ◽  
pp. 963-965
Author(s):  
Ginat W. Mirowski ◽  
Ilona J. Frieden ◽  
Carol Miller

Accidental burns are common, causing signficant morbidity and mortality in all age groups, but they occur most frequently in young children. Each year, tap water burns result in approximately 2600 visits to emergency rooms in the United States1 and cause approximately 200 deaths,2 but these burns are rare in the hospital setting. We describe a case of scald injury in a newborn during routine postnatal bathing that occurred shortly after an increase in the temperature of the hospital water supply due to a Legionella outbreak and discuss precautions that should be used by hospitals to avoid scald injuries. CASE REPORT


2020 ◽  
Vol 25 (1) ◽  
pp. 53-60
Author(s):  
Eman A. Omran ◽  
Faten F. Eisa ◽  
Wafaa M.K. Bakr

OBJECTIVES This study aimed to assess the microbial contamination rate of injectable lipid emulsion (ILE) repackaged syringes at 12 and 24 hours of their infusion time. Probable risk factors associated with contamination of the ILEs were also assessed. In addition, the antimicrobial resistance pattern of the bacterial isolates was also determined. METHODS Samples of ILE were collected from 152 repackaged syringes and their infusion lines after 12 hours and 24 hours of infusion time (73 and 79 samples, respectively). Samples were cultured, the isolates were identified, and the antimicrobial resistance pattern of the bacterial isolates was identified. A checklist was completed throughout the study to observe the compliance to infection control measures by pharmacists (who prepare) and nurses (who administer) the ILE infusions. Results of septic neonatal cultures were taken from records. RESULTS Microbial contamination was found in 15.8% of ILE samples. The 2 most common pathogens found among positive samples were Klebsiella pneumoniae (29.2%) and Candida albicans (20.8%). Microbial contamination of repackaged syringes increased from 9.6% at 12 hours to 21.5% at 24 hours. This difference was found to be statistically significant (p = 0.044). A similar trend of predominance of those 2 pathogens, in both ILE and neonatal cultures, was observed. There was a statistically significant better performance of infection control measures of pharmacists rather than nurses. The K pneumoniae isolates (n = 7) showed antibiotic resistance in the following pattern: gentamicin (71.4%), cefazolin (85.7%), and cefoxitin (85.7%). CONCLUSIONS The rate of ILE contamination was less at 12 hours' than at 24 hours' infusion time. However, contamination rates at 12 hours were unacceptably high. Klebisella pneumoniae and C albicans were the most common pathogens isolated from ILE. Compliance with infection control measures was significantly worse among nurses compared with pharmacists.


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