scholarly journals The Histone Methyltransferase EZH2 Mediates Tumor Progression on the Chick Chorioallantoic Membrane Assay, a Novel Model of Head and Neck Squamous Cell Carcinoma

2013 ◽  
Vol 6 (3) ◽  
pp. 273-281 ◽  
Author(s):  
Min Liu ◽  
Christina Springstead Scanlon ◽  
Rajat Banerjee ◽  
Nickole Russo ◽  
Ronald C Inglehart ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Chorioallantoic Membrane ◽  
Neck Squamous Cell Carcinoma ◽  
Chick Chorioallantoic Membrane ◽  
Novel Model ◽  
Chorioallantoic Membrane Assay

Regulation of tumor progression via the Snail-RKIP signaling pathway by nicotine exposure in head and neck squamous cell carcinoma

Head & Neck ◽  
2015 ◽  
Vol 37 (12) ◽  
pp. 1712-1721 ◽  
Author(s):  
Shin Nieh ◽  
Shu-Wen Jao ◽  
Chin-Yuh Yang ◽  
Yaoh-Shiang Lin ◽  
Yi-Han Tseng ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Signaling Pathway ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Nicotine Exposure

scholarly journals A New Strategy to Find Targets for Anticancer Therapy: Chemokine CXCL14/BRAK Is a Multifunctional Tumor Suppressor for Head and Neck Squamous Cell Carcinoma

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Ryu-Ichiro Hata
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Egf Receptor ◽  
Polymerase Chain Reaction Analysis ◽  
Tumor Formation ◽  
Neck Squamous Cell Carcinoma

In order to find a suppressor(s) of tumor progression in vivo for head and neck squamous cell carcinoma (HNSCC), we searched for molecules downregulated in HNSCC cells when the cells were treated with epidermal growth factor (EGF), whose receptor is frequently overactivated in HNSCC. The expression of BRAK, which is also known as CXC chemokine ligand 14 (CXCL14), was downregulated significantly by the treatment of HNSCC cells with EGF as observed by cDNA microarray analysis followed by reverse-transcriptase polymerase chain reaction analysis and western blotting. The EGF effect on the expression of CXCL14/BRAK was attenuated by the copresence of inhibitors of the EGF receptor, MEK, and ERK. The rate of tumor formation in vivo of BRAK-expressing vector-transfected tumor cells in athymic nude mice or SCID mice was significantly lower than that of mock vector-transfected ones. In addition tumors formed in vivo by the BRAK-expressing cells were significantly smaller than those of the mock-transfected ones. These results indicate that CXCL14/BRAK is a chemokine having suppressive activity toward tumor progression of HNSCC in vivo. Our approach will be useful to find new target molecules to suppress progression of tumors of various origins in addition to HNSCC.

scholarly journals Role of Cyclooxygenase-2 in Tumor Progression and Survival of Head and Neck Squamous Cell Carcinoma

2009 ◽  
Vol 2 (9) ◽  
pp. 823-829 ◽  
Author(s):  
Nabil F. Saba ◽  
Misun Choi ◽  
Susan Muller ◽  
Hyung Ju C. Shin ◽  
Mourad Tighiouart ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Cyclooxygenase 2 ◽  
Neck Squamous Cell Carcinoma

High expression of MLANA in the plasma of patients with head and neck squamous cell carcinoma as a predictor of tumor progression

Head & Neck ◽  
2019 ◽  
Vol 41 (5) ◽  
pp. 1199-1205
Author(s):  
Dorival Mendes Rodrigues‐Junior ◽  
Soon Sim Tan ◽  
Sai Kiang Lim ◽  
Luciano Souza Viana ◽  
Andre Lopes Carvalho ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
High Expression

scholarly journals Decursin inhibits tumor progression in head and neck squamous cell carcinoma by downregulating CXCR7 expression in vitro

2021 ◽  
Vol 47 (2) ◽  
Author(s):  
Mina Joo ◽  
Jong Heo ◽  
Solbi Kim ◽  
Nayoung Kim ◽  
Heung Jeon ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma

Aurora Kinase A Messenger RNA Overexpression Is Correlated with Tumor Progression and Shortened Survival in Head and Neck Squamous Cell Carcinoma

2006 ◽  
Vol 12 (17) ◽  
pp. 5136-5141 ◽  
Author(s):  
Rudolf Reiter ◽  
Peter Gais ◽  
Uta Jütting ◽  
Miriam K. Steuer-Vogt ◽  
Anja Pickhard ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Messenger Rna ◽  
Aurora Kinase ◽  
Neck Squamous Cell Carcinoma ◽  
Aurora Kinase A ◽  
Kinase A

scholarly journals Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma

2016 ◽  
Vol 37 (5) ◽  
pp. 522-529 ◽  
Author(s):  
Kevin D. McCormick ◽  
Arundhati Ghosh ◽  
Sumita Trivedi ◽  
Lin Wang ◽  
Carolyn B. Coyne ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Innate Immune ◽  
Neck Squamous Cell Carcinoma ◽  
Immune Signaling ◽  
Innate Immune Signaling
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