Sexually Transmitted Infections: Impact and Cost-Effectiveness of Prevention

2017 ◽  
pp. 203-232 ◽  
Author(s):  
Harrell W. Chesson ◽  
Philippe Mayaud ◽  
Sevgi O. Aral
Keyword(s):  
Cost Effectiveness ◽  
Sexually Transmitted Infections ◽  
Sexually Transmitted

Achieving successful partner notification: putting together the pieces of the puzzle

2009 ◽  
Vol 20 (9) ◽  
pp. 601-602 ◽  
Author(s):  
C S Estcourt ◽  
L J Sutcliffe ◽  
T Shackleton
Keyword(s):  
Public Health ◽  
Health Care ◽  
Cost Effectiveness ◽  
Sexually Transmitted Infections ◽  
Health Care Professionals ◽  
Partner Notification ◽  
Public Health Measure ◽  
Sexually Transmitted ◽  
Health Measure

Partner notification as a public health measure to reduce transmission of sexually transmitted infections (STIs) is a cornerstone of STI control in most countries. The success of any partner notification strategy is conditional on its acceptability and feasibility to both patients and health-care professionals, its compliance with relevant professional and legislative guidance, and its cost-effectiveness.

scholarly journals Modelling-based evaluation of the costs, benefits and cost-effectiveness of multipathogen point-of-care tests for sexually transmitted infections in symptomatic genitourinary medicine clinic attendees

BMJ Open ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. e020394 ◽  
Author(s):  
Susie E Huntington ◽  
Richéal M Burns ◽  
Emma Harding-Esch ◽  
Michael J Harvey ◽  
Rachel Hill-Tout ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Sexually Transmitted Infections ◽  
Point Of Care ◽  
Secondary Outcome ◽  
Annual Number ◽  
Base Case ◽  
Sexually Transmitted ◽  
Life Years ◽  
Genitourinary Medicine ◽  
Point Of Care Tests

ObjectivesTo quantify the costs, benefits and cost-effectiveness of three multipathogen point-of-care (POC) testing strategies for detecting common sexually transmitted infections (STIs) compared with standard laboratory testing.DesignModelling study.SettingGenitourinary medicine (GUM) services in England.PopulationA hypothetical cohort of 965 988 people, representing the annual number attending GUM services symptomatic of lower genitourinary tract infection.InterventionsThe decision tree model considered costs and reimbursement to GUM services associated with diagnosing and managing STIs. Three strategies using hypothetical point-of-care tests (POCTs) were compared with standard care (SC) using laboratory-based testing. The strategies were: A) dual POCT forChlamydia trachomatis(CT) andNeisseria gonorrhoeae(NG); B) triplex POCT for CT-NG andMycoplasma genitalium(MG); C) quadruplex POCT for CT-NG-MG andTrichomonas vaginalis(TV). Data came from published literature and unpublished estimates.Primary and secondary outcome measuresPrimary outcomes were total costs and benefits (quality-adjusted life years (QALYs)) for each strategy (2016 GB, £) and associated incremental cost-effectiveness ratios (ICERs) between each of the POC strategies and SC. Secondary outcomes were inappropriate treatment of STIs, onward STI transmission, pelvic inflammatory disease in women, time to cure and total attendances.ResultsIn the base-case analysis, POC strategy C, a quadruplex POCT, was the most cost-effective relative to the other strategies, with an ICER of £36 585 per QALY gained compared with SC when using microcosting, and cost-savings of £26 451 382 when using tariff costing. POC strategy C also generated the most benefits, with 240 467 fewer clinic attendances, 808 fewer onward STI transmissions and 235 135 averted inappropriate treatments compared with SC.ConclusionsMany benefits can be achieved by using multipathogen POCTs to improve STI diagnosis and management. Further evidence is needed on the underlying prevalence of STIs and SC delivery in the UK to reduce uncertainty in economic analyses.

scholarly journals AN ECONOMIC MODEL OF SCHOOL-BASED BEHAVIORAL INTERVENTIONS TO PREVENT SEXUALLY TRANSMITTED INFECTIONS

2012 ◽  
Vol 28 (4) ◽  
pp. 407-414 ◽  
Author(s):  
Keith Cooper ◽  
Jonathan Shepherd ◽  
Jo Picot ◽  
Jeremy Jones ◽  
Josephine Kavanagh ◽  
...  
Keyword(s):  
Sexual Behavior ◽  
Cost Effectiveness ◽  
Young People ◽  
Sexually Transmitted Infections ◽  
Economic Model ◽  
Teenage Pregnancy ◽  
Behavioral Interventions ◽  
Sexually Transmitted ◽  
School Based ◽  
Life Years

Objectives: Reducing sexually transmitted infections (STI) and teenage pregnancy through effective health education is a high priority for health policy. Behavioral interventions which teach skills to practice safer sex may reduce the incidence of STIs. We evaluated the cost-effectiveness of school-based behavioral interventions in young people.Methods: We developed an economic model to estimate the total number of STI cases averted, consequent gain in health related quality of life (HRQoL) and savings in medical costs, based on changes in sexual behavior. The parameters for the model were derived from a systematic literature search on the intervention effectiveness, epidemiology of STIs, sexual behavior and lifestyles, HRQoL and health service costs.Results: The costs of providing teacher-led and peer-led behavioral interventions were €5.16 and €18 per pupil, respectively. For a cohort of 1000 boys and 1000 girls aged 15 years, the model estimated that the behavioral interventions would avert two STI cases and save 0.35 Quality Adjusted Life Years (QALYs). Compared to standard education, the incremental cost-effectiveness of the teacher-led and peer-led interventions was €24,268 and €96,938 per QALY gained, respectively.Conclusions: School-based behavioral interventions which provide information and teach young people sexual health skills can bring about improvements in knowledge and increased self-efficacy, though these may be limited in terms of impact on sexual behavior. There was uncertainty around the results due to the limited effect of the intervention on behavioral outcomes and paucity of data for other input parameters.

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