EXPERIMENTAL MEASUREMENTS AND COMPUTATIONAL SIMULATION (COMPUTATIONAL FLUID DYNAMICS) APPLIED FOR THERMAL ANALYSIS OF AN UNINTERRUPTIBLE POWER SUPPLY

2019 ◽  
Vol 11 (4) ◽  
pp. 353-366
Author(s):  
R. J. Pontes Lima ◽  
L. Luppi ◽  
Paulo A. Costa Rocha ◽  
M. E. Vieira da Silva ◽  
C. M. Tavares Cruz ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Thermal Analysis ◽  
Computational Fluid Dynamics ◽  
Power Supply ◽  
Computational Simulation ◽  
Experimental Measurements ◽  
Uninterruptible Power Supply ◽  
Uninterruptible Power

scholarly journals Uninterruptible Power Supply Improves Precision and External Validity of Telomere Length Measurement via qPCR

2020 ◽  
Vol 1 ◽  
Author(s):  
Waylon J. Hastings ◽  
Dan T.A. Eisenberg ◽  
Idan Shalev
Keyword(s):  
Telomere Length ◽  
Power Supply ◽  
External Validity ◽  
High Performance ◽  
Epidemiological Studies ◽  
Storage Conditions ◽  
Amplification Efficiency ◽  
Uninterruptible Power Supply ◽  
Uninterruptible Power ◽  
The Impact

Abstract Technical challenges associated with telomere length (TL) measurements have prompted concerns regarding their utility as a biomarker of aging. Several factors influence TL assessment via qPCR, the most common measurement method in epidemiological studies, including storage conditions and DNA extraction method. Here, we tested the impact of power supply during the qPCR assay. Momentary fluctuations in power can affect the functioning of high-performance electronics, including real-time thermocyclers. We investigated if mitigating these fluctuations by using an uninterruptible power supply (UPS) influenced TL assessment via qPCR. Samples run with a UPS had significantly lower standard deviation (p < 0.001) and coefficient of variation (p < 0.001) across technical replicates than those run without a UPS. UPS usage also improved exponential amplification efficiency at the replicate, sample, and plate levels. Together these improvements translated to increased performance across metrics of external validity including correlation with age, within-person correlation across tissues, and correlation between parents and offspring.

Tonal Noise Reduction in a Radial Fan With Forward-Curved Blades

2014 ◽  
Author(s):  
Manoochehr Darvish ◽  
Bastian Tietjen ◽  
Daniel Beck ◽  
Stefan Frank
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Aerodynamic Performance ◽  
Computational Aeroacoustics ◽  
Experimental Measurements ◽  
Noise Generation ◽  
Tonal Noise ◽  
Outlet Angle ◽  
And Performance ◽  
Impeller Geometry

The main focus of this work is on the geometrical modifications that can be applied to the fan wheel and the volute tongue of a radial fan to reduce the tonal noise. The experimental measurements are performed by using the in-duct method in accordance with ISO 5136. In addition to the experimental measurements, CFD (Computational Fluid Dynamics) and CAA (Computational Aeroacoustics) simulations are carried out to investigate the effects of different modifications on the noise and performance of the fan. It is shown that by modifying the blade outlet angle, the tonal noise of the fan can be reduced without affecting the performance of the fan. Moreover, it is indicated that increasing the number of blades leads to a significant reduction in the tonal noise and also an improvement in the performance. However, this trend is only valid up to a certain number of blades, and a further increment might reduce the aerodynamic performance of the fan. Besides modifying the impeller geometry, new volute tongues are designed and manufactured. It is demonstrated that the shape of the volute tongue plays an important role in the tonal noise generation of the fan. It is possible to reduce the tonal noise by using stepped tongues which produce phase-shift effects that lead to an effective local cancellation of the noise.

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