Three-Dimensional Planning Tool for Breast Conserving Surgery: A Technological Review

2018 ◽  
Vol 46 (6) ◽  
pp. 523-580 ◽  
Author(s):  
Sara P. Oliveira ◽  
Pedro Morgado ◽  
Pedro F. Gouveia ◽  
João F. Teixeira ◽  
Silvia Bessa ◽  
...  
2020 ◽  
Vol 1 (1) ◽  
pp. 62-70
Author(s):  
Amir H Sadeghi ◽  
Wouter Bakhuis ◽  
Frank Van Schaagen ◽  
Frans B S Oei ◽  
Jos A Bekkers ◽  
...  

Abstract Aims Increased complexity in cardiac surgery over the last decades necessitates more precise preoperative planning to minimize operating time, to limit the risk of complications during surgery and to aim for the best possible patient outcome. Novel, more realistic, and more immersive techniques, such as three-dimensional (3D) virtual reality (VR) could potentially contribute to the preoperative planning phase. This study shows our initial experience on the implementation of immersive VR technology as a complementary research-based imaging tool for preoperative planning in cardiothoracic surgery. In addition, essentials to set up and implement a VR platform are described. Methods Six patients who underwent cardiac surgery at the Erasmus Medical Center, Rotterdam, The Netherlands, between March 2020 and August 2020, were included, based on request by the surgeon and availability of computed tomography images. After 3D VR rendering and 3D segmentation of specific structures, the reconstruction was analysed via a head mount display. All participating surgeons (n = 5) filled out a questionnaire to evaluate the use of VR as preoperative planning tool for surgery. Conclusion Our study demonstrates that immersive 3D VR visualization of anatomy might be beneficial as a supplementary preoperative planning tool for cardiothoracic surgery, and further research on this topic may be considered to implement this innovative tool in daily clinical practice. Lay summary Over the past decades, surgery on the heart and vessels is becoming more and more complex, necessitating more precise and accurate preoperative planning. Nowadays, operative planning is feasible on flat, two-dimensional computer screens, however, requiring a lot of spatial and three-dimensional (3D) thinking of the surgeon. Since immersive 3D virtual reality (VR) is an upcoming imaging technique with promising results in other fields of surgery, we aimed in this study to explore the additional value of this technique in heart surgery. Our surgeons planned six different heart operations by visualizing computed tomography scans with a dedicated VR headset, enabling them to visualize the patient’s anatomy in an immersive and 3D environment. The outcomes of this preliminary study are positive, with a much more reality-like simulation for the surgeon. In such, VR could potentially be beneficial as a preoperative planning tool for complex heart surgery.


Author(s):  
Mark Asselin

When a woman is diagnosed with breast cancer, several treatment options are considered including breast conserving surgery. In this type of surgery, the goal is to completely remove the cancer while leaving as much healthy breast tissue as possible. This is a clinical judgement of high consequence since resecting less tissue is cosmetically appealing but increases the chances of leaving cancer cells behind, known as a positive margin. Conventionally, this operation is performed with an electrocautery – imagine it as an electronic knife – which seals tissue as it cuts and produces small amounts of surgical smoke in the process. In most operating rooms today this smoke is treated as a by product, and it is discarded with no further consideration. But this smoke is rich with useful information; it contains traces of the molecules the knife passed through when the smoke was generated. The intelligent knife (iKnife) analyzes this smoke to determine the pathology of tissue the surgeon’s knife has passed through – whether the tissue is cancerous or not. We have coupled the iKnife with an electromagnetic position tracking system to create a three dimensional spatially resolved malignancy map showing where the surgeon’s knife has encountered cancerous tissue. We have developed a functional prototype and have approval for a first clinical safety and feasibility trial. We hope the spatial map will help surgeons to successfully remove the entire malignancy with the smallest amount of healthy tissue while maintaining negative margins – a successful surgical outcome for the patient.


2011 ◽  
Vol 44 (2) ◽  
pp. 418-423 ◽  
Author(s):  
Janik Zikovsky ◽  
Peter F. Peterson ◽  
Xiaoping P. Wang ◽  
Matthew Frost ◽  
Christina Hoffmann

Beam time at large user-program-based X-ray and neutron scattering facilities is in high demand and always at a premium.CrystalPlan, a highly efficient experiment-planning software, has been developed to maximize the use of available beam time per sample per experiment. This program can calculate and optimize the data coverage of a crystal in reciprocal space in a single-crystal diffraction time-of-flight experiment.CrystalPlancan help a user build an experiment plan that will acquire the most unique data possible, with sufficient coverage but limited redundancy, therefore increasing scientific productivity. A user-friendly graphical user interface, including a three-dimensional viewer, an automated coverage optimizer and an option to reorient the crystal for the measurement of selectedhklreflections on specific detector positions, are among its useful features. A sample use case of the program with the TOPAZ beamline at the Spallation Neutron Source will be presented.


2021 ◽  
Vol 9 (4) ◽  
Author(s):  
Astrid MBChB ◽  
Rachel Connell ◽  
Stephanie Dean ◽  
Rosa Micco ◽  
Naser Alotaibi ◽  
...  

Introduction Three-dimensional surface imaging (3D-SI) of the breasts enables the measurement of anthropometric distances and breast volume. These measurements may be used in surgical planning and to facilitate clear communication with patients. The aim of this study was to compare measurements using a portable 3D-SI system, Crisalix, with a more established non-mobile camera, the VECTRA XT. Methods Participants were imaged three times using the Crisalix and the VECTRA XT system. Breast volume, sternal notch to nipple distance, nipple to nipple distance and breast width were measured. Intra-observer agreement was measured using the co-efficient of variation (CV). Agreement between the two methods was represented with Bland Altman agreement plots. Results Intra-method variation was low for both methods (maximum CV 3.3% for Crisalix and 3.2% for VECTRA XT), with only nipple-to-nipple distance being statistically significant, marginally in favour of VECTRA. The mean inter-method differences were small but the limits of agreement (LoA) were wide for all parameters: best for sternal notch to nipple distance, mean difference (MD) -0.03cm and LoA 1.8 to -1.8cm; the widest LoA were for breast volume: MD 31.1cm3 and LoA 286.7 to -244.6cm3. Conclusion This is the first comparison of anthropometric distances and breast volume measured using the two most widely used 3D-SI systems, Crisalix and VECTRA XT. Intra-method variation is low but currently it would not be appropriate to use the two systems interchangeably due to the wide limits of agreement for all four parameters assessed.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 71
Author(s):  
Manwar Abdulelah Al-Naqqash ◽  
Enas Khudhair Al-Bdaer ◽  
Wieeam Abdulfattah Saleh Saleh ◽  
Ahmed Salih Al-Shewered

Background: Breast cancer is a common malignancy in Iraq, accounting for one-third of female cancers in the Iraqi Cancer Registry. Radiotherapy confers benefits for local control and progression free survival (PFS) in patients with breast cancer. This study aimed to assess PFS in patients treated by hypofractionated three-dimensional conformal radiotherapy (3DCRT) and correlate PFS with patients' clinical and pathological profiles. Methods: We retrospectively reviewed 299 women with breast cancer treated at Baghdad Radiation Oncology Center between October 2017 and May 2018. Regarding radiotherapy, 4005 cGy in 15 fractions over 3 weeks was adopted as standard practice for patients undergoing mastectomy and 4005 cG in 15 fractions + 1000 cG in 5 fractions as a booster dose for women undergoing breast-conserving surgery. Results: Age ranged from 25 to 75 years, and the mean age was 49.9±10.99 years. The most common stage was T2 (156, 53.9%), which mostly comprised luminal A (105, 36.3%). The results showed a high frequency of N1 (109, 37.2%), with luminal A (69, 23.4%). Relapse occurred in 35/299 (11.7%) patients, and the chest wall was a common relapse site in 9 of these patients (25.9%). Conclusions: We conclude that adjuvant radiotherapy reduces locoregional recurrence, distant metastasis and mortality rate.


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