Transcriptional Regulation of Vertebrate Hox Genes during Embryogenesis

1997 ◽  
Vol 7 (3) ◽  
pp. 195-213 ◽  
Author(s):  
Thomas Lufkin
Keyword(s):  
Transcriptional Regulation ◽  
Hox Genes

scholarly journals Transcriptional Regulation and Implications for Controlling Hox Gene Expression

2022 ◽  
Vol 10 (1) ◽  
pp. 4
Author(s):  
Zainab Afzal ◽  
Robb Krumlauf
Keyword(s):  
Transcriptional Regulation ◽  
Molecular Mechanisms ◽  
Hox Genes ◽  
Regional Identity ◽  
Regulatory Mechanisms ◽  
Regulation Of Transcription ◽  
Axial Patterning ◽  
Hox Gene ◽  
Molecular Framework ◽  
Combinatorial Code

Hox genes play key roles in axial patterning and regulating the regional identity of cells and tissues in a wide variety of animals from invertebrates to vertebrates. Nested domains of Hox expression generate a combinatorial code that provides a molecular framework for specifying the properties of tissues along the A–P axis. Hence, it is important to understand the regulatory mechanisms that coordinately control the precise patterns of the transcription of clustered Hox genes required for their roles in development. New insights are emerging about the dynamics and molecular mechanisms governing transcriptional regulation, and there is interest in understanding how these may play a role in contributing to the regulation of the expression of the clustered Hox genes. In this review, we summarize some of the recent findings, ideas and emerging mechanisms underlying the regulation of transcription in general and consider how they may be relevant to understanding the transcriptional regulation of Hox genes.

Interplay between Pur α and Egr-1 in the transcriptional regulation of amyloid precursor protein gene expression

2010 ◽  
Vol 34 (8) ◽  
pp. S27-S27
Author(s):  
Jianqi Cui ◽  
Xiuying Pei ◽  
Qian Zhang ◽  
Bassel E. Sawaya ◽  
Xiaohong Lu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Transcriptional Regulation ◽  
Amyloid Precursor Protein ◽  
Protein Gene ◽  
Precursor Protein ◽  
Amyloid Precursor Protein Gene

Interaction of EGR-1 and Sp family members is involved in the transcriptional regulation of the human NHE-2 gene promoter

2001 ◽  
Vol 120 (5) ◽  
pp. A41-A41
Author(s):  
J MALAKOOTI ◽  
V MEMARK ◽  
P DUDEJA ◽  
K RAMASWAMY
Keyword(s):  
Transcriptional Regulation ◽  
Family Members ◽  
Gene Promoter

The time course of transcriptional regulation of the ‘constitutive’ cyclooxgenase-1 gene by Helicobacter pylori†

2001 ◽  
Vol 120 (5) ◽  
pp. A659-A659 ◽  
Author(s):  
M BYRNE ◽  
P CORCORAN ◽  
K SHEEHAN ◽  
J ATHERTON ◽  
D FITZGERALD ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Transcriptional Regulation ◽  
Time Course
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