Crop Immune Response Post–Salmonella Enteritidis Challenge in Eight Commercial Egg-Layer Strains and Specific-Pathogen-Free White Leghorn Chickens

2008 ◽  
Vol 52 (1) ◽  
pp. 79-87 ◽  
Author(s):  
L. E. Vaughn ◽  
P. S. Holt ◽  
R. W. Moore ◽  
R. K. Gast ◽  
K. E. Anderson
Keyword(s):  
Immune Response ◽  
Salmonella Enteritidis ◽  
Specific Pathogen Free ◽  
White Leghorn ◽  
Specific Pathogen ◽  
Response Post

scholarly journals Effect of proanthocyanidin-rich extract from Pinus radiata bark on immune response of specific-pathogen-free White Leghorn chickens

2011 ◽  
Vol 90 (5) ◽  
pp. 977-982 ◽  
Author(s):  
I.-J. Park ◽  
S.-Y. Cha ◽  
M. Kang ◽  
Y.-S. So ◽  
H.-G. Go ◽  
...  
Keyword(s):  
Immune Response ◽  
Pinus Radiata ◽  
Specific Pathogen Free ◽  
White Leghorn ◽  
Specific Pathogen ◽  
Pinus Radiata Bark

scholarly journals Effect of Antibiotics on the Colonization of Live Attenuated Salmonella Enteritidis Vaccine in Chickens

2021 ◽  
Vol 8 ◽  
Author(s):  
Jiangang Hu ◽  
Chuanyan Che ◽  
Jiakun Zuo ◽  
Xiangpeng Niu ◽  
Zhihao Wang ◽  
...  
Keyword(s):  
Vaccine Strain ◽  
Salmonella Enteritidis ◽  
Antibiotic Use ◽  
Live Vaccine ◽  
Live Vaccine Strain ◽  
Specific Pathogen Free ◽  
Live Vaccines ◽  
The World ◽  
Specific Pathogen ◽  
Effective Use

Salmonellosis, caused by Salmonella Enteritidis, is a prevalent zoonosis that has serious consequences for human health and the development of the poultry sector. The Salmonella Enteritis live vaccine (Sm24/Rif12/Ssq strain) is used to prevent Salmonella Enteritidis around the world. However, in some parts of the world, poultry flocks are frequently raised under intensive conditions, with significant amounts of antimicrobials to prevent and treat disease and to promote growth. To investigate whether antibiotic use influences the colonization of orally administered Salmonella live vaccines, 240 1-day-old specific pathogen-free chicks were randomly divided into 24 groups of 10 animals for this study. The different groups were treated with different antibiotics, which included ceftiofur, amoxicillin, enrofloxacin, and lincomycin–spectinomycin. Each group was immunized 2, 3, 4, and 5 days after withdrawal, respectively. At 5 days after immunization, the blood, liver, and ceca with contents were collected for the isolation of the Salmonella live vaccine strain. The result showed that no Salmonella vaccine strain was isolated in the blood and liver of the chicks in those groups. The highest number of Salmonella vaccine strains was isolated in the cecum from chicks vaccinated 2 days after ceftiofur withdrawal, and no Salmonella vaccine strain was isolated from the cecum in chicks immunized 3 days after ceftiofur withdrawal. Among the chickens immunized 4 days after the withdrawal of amoxicillin, enrofloxacin, and lincomycin–spectinomycin, the number of Salmonella vaccine colonization in the cecum was the highest, which was higher than that of the chickens immunized at other withdrawal interval (2, 3, and 5 days) groups and was higher than that of the chickens without treatment (P < 0.05). This study provides a reference for the effective use of the Salmonella Enteritidis live vaccine and key antibiotics commonly utilized in the poultry industry.

scholarly journals Specific-Pathogen-Free Pigs as an Animal Model for Studying Chlamydia trachomatis Genital Infection

2005 ◽  
Vol 73 (12) ◽  
pp. 8317-8321 ◽  
Author(s):  
Daisy Vanrompay ◽  
Thi Q. T. Hoang ◽  
Liselotte De Vos ◽  
Kristel Verminnen ◽  
Taher Harkinezhad ◽  
...  
Keyword(s):  
Immune Response ◽  
Animal Model ◽  
Chlamydia Trachomatis ◽  
Immunoglobulin M ◽  
Large Animal Model ◽  
Genital Infection ◽  
Large Animal ◽  
Specific Pathogen Free ◽  
Humoral Immune ◽  
Specific Pathogen

ABSTRACT The purpose of the present study was to evaluate pigs as a large-animal model for female genital infection with two Chlamydia trachomatis human serovar E strains. Sixteen-week-old specific-pathogen-free female pigs (gilts) were intravaginally infected with the trachoma type E reference strain Bour or the urogenital serovar E strain 468. Several conclusions can be drawn from our findings on the pathogenicity of a primary C. trachomatis genital infection in gilts. First of all, we demonstrated that the serovar E strains Bour and 468 could ascend in the genital tract of gilts. The serovar E strains could replicate in the superficial columnar cervical epithelium and in the superficial epithelial layer of the uterus, which are known to be the specific target sites for a C. trachomatis genital infection in women. Second, inflammation and pathology occurred at the replication sites. Third, the organisms could trigger a humoral immune response, as demonstrated by the presence of immunoglobulin M (IgM), IgG, and IgA in both serum and genital secretion samples. Our findings imply that the pig model might be useful for studying the pathology, pathogenesis, and immune response to a C. trachomatis infection of the genital system.

Immune response of neonatal specific pathogen-free cats to experimental infection with Bartonella henselae

1999 ◽  
Vol 71 (3-4) ◽  
pp. 233-243 ◽  
Author(s):  
Lynn Guptill ◽  
Leonard Slater ◽  
Ching-Ching Wu ◽  
Lawrence T Glickman ◽  
Tsang-Long Lin ◽  
...  
Keyword(s):  
Immune Response ◽  
Experimental Infection ◽  
Bartonella Henselae ◽  
Specific Pathogen Free ◽  
Specific Pathogen

Interactions ofPlasmodium juxtanucleareand chicken anaemia virus: establishing a model

Parasitology ◽  
2013 ◽  
Vol 140 (14) ◽  
pp. 1777-1788 ◽  
Author(s):  
PATRICIA SILVEIRA ◽  
SANDRA Y. G. MARIN ◽  
PATRICIA A. MOREIRA ◽  
BÁRBARA B. TOCANTINS ◽  
GUSTAVO LACORTE ◽  
...  
Keyword(s):  
Avian Malaria ◽  
Haemoglobin Concentration ◽  
Clinical Analysis ◽  
Bursa Of Fabricius ◽  
Control Group ◽  
Specific Pathogen Free ◽  
White Leghorn ◽  
Chicken Anaemia Virus ◽  
Malarial Infection ◽  
Specific Pathogen

SUMMARYThe pathogensPlasmodium juxtanucleareand chicken anaemia virus (CAV) are easily transmitted and potentially harmful to chickens. In this study, we established an experimental model to investigate the effects of avian malaria caused byP. juxtanuclearein white leghorn specific-pathogen-free (SPF) chicks previously immunosuppressed with CAV. Parasitaemia, haematological variables and clinical and pathological parameters were determined in four different experimental groups: chicks coinfected by CAV andP. juxtanuclearestrain (Coinfected group), chicks exclusively infected by CAV (CAV group) orP. juxtanucleare(Malaria group) and uninfected chicks (Control group). Our data demonstrated thatP. juxtanucleareparasitaemia was significantly higher in the Coinfected group. Furthermore, haematological parameters, including the RBC, haematocrit and haemoglobin concentration were significantly reduced in coinfected chicks. In agreement with the changes observed in haematological features, the mortality among coinfected chicks was higher compared with animals with single infections. Clinical analysis indicated moderate changes related to different organs size (bursa of Fabricius, heart and liver) in coinfected birds. The experimental coinfection of SPF chickens withP. juxtanucleareand CAV may represent a research tool for the study of avian malaria after CAV immunosuppression, enabling measurement of the impacts caused by different pathogens during malarial infection.

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