scholarly journals Osteoprotegerin is a new marker of cardiovascular diseases

2017 ◽  
Vol 89 (4) ◽  
pp. 91-94 ◽  
Author(s):  
A F Verbovoy ◽  
I A Tsanava ◽  
E V Mitroshina ◽  
L A Sharonova
Keyword(s):  
Heart Failure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiovascular Diseases ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Factor Α ◽  
Progression Of Atherosclerosis ◽  
Necrosis Factor

Osteoprotegerin (OPG) is a glycoprotein that is a representative of the tumor necrosis factor-α receptor superfamily. Information about the possible role of OPG in the development of cardiovascular diseases has begun to appear in the literature in recent years. This review discusses the role of increasing the level of OPG in the development and progression of atherosclerosis and as a consequence of coronary heart disease and chronic heart failure.

Evidence for a role of tumor necrosis factor α in disturbances of triglyceride and glucose metabolism predisposing to coronary heart disease

Metabolism ◽  
1998 ◽  
Vol 47 (1) ◽  
pp. 113-118 ◽  
Author(s):  
Stefan Jovinge ◽  
Anders Hamsten ◽  
Per Tornvall ◽  
Anthony Proudler ◽  
Peter Båvenholm ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Tumor Necrosis Factor ◽  
Glucose Metabolism ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Factor Α ◽  
Necrosis Factor

scholarly journals Association of Genetic Polymorphism of Tumor Necrosis Factor-α in the Development of Coronary Heart Disease in Elderly Patients

2021 ◽  
pp. 81-88
Author(s):  
Bekkhan Saidmagomedovich Mezhidov ◽  
Khava Idrisovna Bekova ◽  
Aishat Alikovna Edieva ◽  
Khava Ismailovna Madalova ◽  
Victoria Alekseevna Malakhova ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Cardiovascular Pathology ◽  
Inflammatory Processes ◽  
Factor Α ◽  
Necrosis Factor

The research project outlines a new look at the concept of "inflammaging" and the role of the subclinical inflammatory process in various age-associated pathology, in particular coronary heart disease. Particular attention is paid to the tumor necrosis factor-α -cytokine, which plays an important role in the pathogenesis of chronic inflammatory processes and in the aging process. The increased content of tumor necrosis factor-α leads to the emergence and accumulation of various diseases, disability and mortality of elderly and senile people. Tumor necrosis factor-α influences various risk factors for cardiovascular pathology. This substance aggravates various breakdowns in metabolism, primarily causing insulin resistance. Tumor necrosis factor-α is a key cytokine that stimulates bone resorption (osteoporosis) and sarcopenia. Currently available data prove the important role of tumor necrosis factor-α in various age-associated pathologies.

A polymorphism in the promoter of the tumor necrosis factor-α gene (−308) is associated with coronary heart disease in type 2 diabetic patients

2003 ◽  
Vol 167 (2) ◽  
pp. 257-264 ◽  
Author(s):  
Joan Vendrell ◽  
José-Manuel Fernandez-Real ◽  
Cristina Gutierrez ◽  
Alberto Zamora ◽  
Inmaculada Simon ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Factor Α ◽  
Type 2 Diabetic ◽  
Necrosis Factor
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