scholarly journals Dexmedetomidine as an adjuvant to Nalbuphine in patient controlled analgesia for post-operative pain in Laparoscopic Cholecystectomy: A preliminary study

2019 ◽  
pp. 012-018
Author(s):  
M Elsebae Magdy
2009 ◽  
Vol 5 ◽  
pp. 1744-8069-5-32 ◽  
Author(s):  
Ene-choo Tan ◽  
Eileen CP Lim ◽  
Yik-ying Teo ◽  
Yvonne Lim ◽  
Hai-yang Law ◽  
...  

2007 ◽  
Vol 35 (4) ◽  
pp. 497-507 ◽  
Author(s):  
YY Lee ◽  
KH Kim ◽  
YH Yom

This study identified predictive factors for post-operative nausea and vomiting (PONV) in patients using patient-controlled analgesia (PCA) and developed five predictive model pathways to calculate the probability of PONV using decision tree analysis. The sample consisted of 1181 patients using PCA. Data were collected using: a specifically designed check-off form to collect patient-, surgery-, anaesthesia- and post-operation-related data; the Beck Anxiety Inventory® to measure pre-operative anxiety; and a visual analogue scale, to measure post-operative pain. The incidence of PONV was 27.7%. Nine factors were highly predictive of PONV in our five model pathways: gender, obesity, anxiety, history of previous PONV, history of motion sickness, inhalation of nitrous oxide during operation, use of inhalational agents, starting oral fluid/food intake after operation, and post-operative pain. With these five predictive model pathways, we can predict the probability of PONV in an individual patient according to their individual characteristics.


2018 ◽  
Vol 6 (2) ◽  
pp. 6
Author(s):  
Kalpana Kharbuja ◽  
Mahesh Sharma ◽  
Nil Raj Sharma

Introduction: Though the development of minimally invasive surgery  has revolutionized the field of surgery,  post-operative pain is still a significant issue. Unlike in the past, concerns about adverse effects have limited the role of opioids in post-operative pain management. This study aims to compare the effectiveness of intravenous paracetamol and  diclofenac as postoperative analgesia in laparoscopic cholecystectomy. Methods:One hundred and twenty eight patients of American Society of Anesthesiologists (ASA) categories I and II  included in this study  were divided into two groups. Anesthesia induction and maintenance were standardized. The first group received 15mg/kg (maximum 1gm) intravenous paracetamol and the second group received 2mg/kg (maximum 75mg) intravenous diclofenac 30 minutes prior to ending of surgery. A questionnaire was responded by patients and chart was maintained by visual analogue scale. Mann Whitney U test was used to analyze quantitative data and Chi-square test for categorical data. P value <0.05 was considered statistically significant. Results:  Profiles of hemodynamic changes were almost similar in both groups with respect to heart rate and blood pressure. However, paracetamol infusion provided hemodynamic stability in post-operative period. We observed statistically significant differences  in visual analogue scale between the two groups. Most of the patients in paracetamol group had low mean pain scores in post-operative period and provided an extended analgesia compared to diclofenac. No serious postoperative complication was observed in  paracetamol group.   Conclusion: Administration of intravenous paracetamol has better and prolonged analgesic effect  with low mean pain score and less requirement for rescue analgesia compared to diclofenac.


2021 ◽  
pp. 187-189
Author(s):  
Garima Anant ◽  
Aman Kaur ◽  
Prakriti Prakriti

Background: Quadratus lumborum block is done ultrasonographically in thoracolumbar fascial plane at the level of quadratus lumborum muscle to decrease post-operative pain in patients who underwent laparoscopic cholecystectomy . Methods: A prospective, randomized and comparative study was conducted in Pt. B.D. Sharma PGIMS, Rohtak. After informed and written consent, patients were recruited in the study and assigned into 2 groups. A detailed history was taken and examination was carried out. Group 1 patients received Inj.. diclofenac IM (intramuscular) 75 mg and in group 2 Bilateral QL (quadratus lumborum) block was given using 15 ml of 0.25 percent levobupivacaine. The results were measured by VAS score and 24hrs fentanyl consumption. At the end of the study, data was compiled and analyzed using SPSS version 17. Results: In the present study, there was no statistical signicant difference between the two groups. We found that the patients who received quadratus lumborum block had lesser fentanyl consumption and the VAS scores were also better.


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