scholarly journals Measurement of duodenal motility using implanted strain gauges v1 (protocols.io.2irgcd6)

protocols.io ◽  
2019 ◽  
Author(s):  
Terry Powley ◽  
Zhenjun Tan ◽  
Matthew Ward
Keyword(s):  
Strain Gauges ◽  
Duodenal Motility

5-Hydroxytryptophan modulates postprandial motor patterns of canine proximal small intestine

1990 ◽  
Vol 68 (12) ◽  
pp. 1495-1502 ◽  
Author(s):  
M. L. Siegle ◽  
S. Bühner ◽  
H. J. Ehrlein
Keyword(s):  
Motor Pattern ◽  
Strain Gauges ◽  
Motor Patterns ◽  
Temporal And Spatial Distribution ◽  
Jejunal Segment ◽  
Duodenal Motility ◽  
Computerized Analysis ◽  
Proximal Small Intestine ◽  
Temporal And Spatial ◽  
Stimulation Of

The aim of the study was to clarify whether 5-hydroxytryptophan (5-HTP) stimulates the postprandial motor pattern of the duodenum in a similar way as that of the adjacent jejunal segment in dogs. Computerized analysis of motor patterns recorded by closely spaced strain gauges focused on the temporal and spatial distribution of the contractions. Results indicate that 5-HTP increased the incidence and the length of the spread of contraction waves after both an acaloric and a nutrient meal in the duodenum as well as in the adjacent jejunal segment. Effects were more pronounced after the nutrient than after the acaloric meal. After the nutrient meal, but not after the acaloric meal, 5-HTP additionally enhanced the number of both duodenal and jejunal contractions per minute and increased the force of duodenal contractions. The acaloric meal induced significant differences in the motor patterns between the duodenum and the adjacent jejunum. 5-HTP abolished these differences owing to a relatively stronger stimulation of duodenal motility. 5-HTP did not affect gastric emptying of both meals. We conclude (i) that 5-HTP is a potent stimulator of propagated contractions both in the duodenum and the adjacent jejunal segment and (ii) that intestinal motor patterns can be regulated independently of gastric emptying.Key words: 5-hydroxytryptophan, duodenum, jejunum, gastrointestinal motility, length of contraction spread, computerized analysis.

Rat gastroduodenal motility in vivo: involvement of NO and ATP in spontaneous motor activity

1998 ◽  
Vol 275 (5) ◽  
pp. G889-G896 ◽  
Author(s):  
Ian Glasgow ◽  
Kamal Mattar ◽  
Anthony Krantis
Keyword(s):  
Motor Activity ◽  
No Synthase ◽  
Strain Gauges ◽  
Sprague Dawley ◽  
Duodenal Motility ◽  
Sprague Dawley Rats ◽  
Motor Activities ◽  
Gastroduodenal Motility ◽  
Synthase Inhibitor

Our studies of fasted anesthetized rats have shown that all spontaneous relaxations of the antrum are nitric oxide (NO) dependent. Duodenal motility is patterned into propagating “grouped” motor activity interposed with “intergroup” periods of nonpropagating motor activity; in the duodenum, only intergroup relaxations are NO dependent. We examined the involvement of NO and ATP in spontaneous motor activities of the gastroduodenum in vivo: contractions and relaxations were recorded and analyzed simultaneously from the antrum (S1) and proximal duodenum (D1) of anesthetized Sprague-Dawley rats ( n = 10/group), using extraluminal foil strain gauges. Treatment with the NO synthase inhibitor N G-nitro-l-arginine methyl ester (l-NAME; 10 mg/kg iv) attenuated ( P < 0.05) antral and intergroup relaxations, whereas grouped relaxations were enhanced ( P < 0.05). These effects were reversed with l-arginine (300 mg/kg iv). l-NAME also increased ( P < 0.05) the amplitude of duodenal contractions. ATP (8 mg ⋅ kg−1 ⋅ min−1iv) stimulated relaxations at S1and D1 that were blocked by the P2-purinoceptor antagonist suramin (60 mg/kg iv). This treatment did not affect spontaneous antral relaxations; however, duodenal grouped relaxations were attenuated. Desensitization to the P2x-purinoceptor agonist α,β-methylene ATP (300 μg/kg iv) gave results similar to suramin. In contrast, the P2y-purinoceptor agonist 2-methylthio-ATP (2-MeS-ATP; 360 μg/kg iv) evoked duodenal relaxations that were attenuated byl-NAME, and desensitization to 2-MeS-ATP attenuated intergroup relaxations. Spontaneous relaxations of the rat antrum and duodenal intergroup relaxations are NO dependent. Both gut regions relax in response to systemically administered ATP; this response is sensitive to suramin. Grouped duodenal relaxations display functional sensitivity to suramin and P2x- purinoceptor desensitization, indicative of the involvement of ATP and P2x purinoceptors. P2y purinoceptors must also be present; however, these occur on elements releasing NO. Although NO does not mediate grouped relaxations or duodenal contractions, the sensitivity of these responses tol-NAME indicates that the pathway(s) controlling these responses is modulated by NO.

Use of a dentin bonding agent for the fixation of strain gauges on bone

2021 ◽  
pp. 104545
Author(s):  
Tanja Grobecker-Karl ◽  
Kamran Orujov ◽  
Virgilia Klär ◽  
Matthias Karl
Keyword(s):  
Bonding Agent ◽  
Strain Gauges ◽  
Dentin Bonding ◽  
Dentin Bonding Agent

Cold expansion of rail-end-bolt holes: finite element predictions and experimental validation by DIC and strain gauges

2021 ◽  
pp. 106275
Author(s):  
Giovanni Pio Pucillo ◽  
Alessandro Carrabs ◽  
Stefano Cuomo ◽  
Adam Elliott ◽  
Michele Meo
Keyword(s):  
Finite Element ◽  
Experimental Validation ◽  
Strain Gauges ◽  
Cold Expansion ◽  
Bolt Holes

scholarly journals Giant gauge factor of Van der Waals material based strain sensors

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Wenjie Yan ◽  
Huei-Ru Fuh ◽  
Yanhui Lv ◽  
Ke-Qiu Chen ◽  
Tsung-Yin Tsai ◽  
...  
Keyword(s):  
Carrier Mobility ◽  
Large Range ◽  
Van Der Waals ◽  
High Sensitivity ◽  
Strain Sensors ◽  
Strain Gauges ◽  
Gauge Factor ◽  
Proof Of Concept ◽  
High Flexibility ◽  
Small Deformations

AbstractThere is an emergent demand for high-flexibility, high-sensitivity and low-power strain gauges capable of sensing small deformations and vibrations in extreme conditions. Enhancing the gauge factor remains one of the greatest challenges for strain sensors. This is typically limited to below 300 and set when the sensor is fabricated. We report a strategy to tune and enhance the gauge factor of strain sensors based on Van der Waals materials by tuning the carrier mobility and concentration through an interplay of piezoelectric and photoelectric effects. For a SnS2 sensor we report a gauge factor up to 3933, and the ability to tune it over a large range, from 23 to 3933. Results from SnS2, GaSe, GeSe, monolayer WSe2, and monolayer MoSe2 sensors suggest that this is a universal phenomenon for Van der Waals semiconductors. We also provide proof of concept demonstrations by detecting vibrations caused by sound and capturing body movements.

scholarly journals Comparison of Resistive and Optical Strain Measurement for Early Fracture Detection

2020 ◽  
Vol 6 (3) ◽  
pp. 196-199
Author(s):  
Alina Carabello ◽  
Constanze Neupetsch ◽  
Michael Werner ◽  
Christian Rotsch ◽  
Welf-Guntram Drossel ◽  
...  
Keyword(s):  
Surgical Training ◽  
Error Detection ◽  
Strain Measurement ◽  
Testing Machine ◽  
Image Correlation ◽  
Strain Gauges ◽  
Measurement Technology ◽  
Bone Surface ◽  
Fracture Detection ◽  
Local Strains

AbstractTo increase learning success in surgical training, physical simulators are supplemented by measurement technology to generate and record objective feedback and error detection. An opportunity to detect fractures following hip stem implantation early can be measurement of occurring strains on bone surface. These strains can be determined while using strain gauges, digital image correlation (DIC) or photoelasticity. In this research strain gauges and DIC were compared regarding their suitability as strain measurement tools for use in physical simulators. Therefore a testing method was described to replicate the implantation of a hip stem. Testing devices modelled on a realistic prosthesis were pressed into prepared porcine femora in a two-step procedure with a material testing machine. The local strains occurring on bone surface were determined using an optical measurement system for DIC and strain gauges. The initial fractures in the tested femora are located medial-anterior in most cases (73,6%). With increasing indentation depth of the test device, the strains on bone surface increase. Comparing the local strains determined by DIC and strain gauges consistencies in curves are noticeable. Maximal determined strains before fracturing amount to 0,69% with strain gauges and 0,75% with DIC. In the range of the fracture gap, strain gradients are determined by using DIC. However the detected surfaces are of low quality caused by gaps and motion artefacts. The results show strains on bone surfaces for early fracture detection are measurable with strain gauges and DIC. DIC is assessed as less suitable compared to strain gauges. Furthermore strain gauges have greater level of integration and economic efficiency, so they are preferred the use in surgical training simulators.

Influence of motilin and cholecystokinin on sphincter of Oddi and duodenal mobility

1987 ◽  
Vol 253 (5) ◽  
pp. G679-G683 ◽  
Author(s):  
E. L. Muller ◽  
P. A. Grace ◽  
R. L. Conter ◽  
J. J. Roslyn ◽  
H. A. Pitt
Keyword(s):  
Sphincter Of Oddi ◽  
Prairie Dogs ◽  
Prairie Dog ◽  
Cholecystokinin Octapeptide ◽  
Side Hole ◽  
Hole Pressure ◽  
Duodenal Motility ◽  
Sphincter Of Oddi Motility ◽  
Duodenal Lumen ◽  
Distal Port

The sphincter of Oddi and the duodenum exhibit cyclical activity in phase with the migrating myoelectric complex. Both motilin and cholecystokinin have been shown to modulate gastrointestinal and sphincter of Oddi motility. However, previous studies have not monitored the effects of these hormones on simultaneously recorded sphincter of Oddi and duodenum pressures. The present investigation was undertaken, therefore, to determine the influence of both motilin and cholecystokinin on simultaneously recorded sphincter of Oddi and duodenal motility. In seven anesthetized prairie dogs, a triple-lumen, side-hole, pressure-monitored perfusion catheter was positioned with the proximal port in the sphincter of Oddi and the distal port in the duodenal lumen. Sphincter of Oddi and duodenal motility was recorded before and during 20-min infusions of motilin and cholecystokinin octapeptide (CCK-8) at 1, 10, and 100 ng.kg-1.min-1. Both hormones produced dose-related increases in sphincter of Oddi and duodenal motility. No response was observed with either hormone at 1 ng.kg-1.min-1. At 10 ng.kg-1.min-1, the duodenum was slightly more sensitive to motilin than to CCK-8, while the sphincter of Oddi was equally affected by both hormones. At 100 ng.kg-1.min-1, both hormones stimulated the sphincter of Oddi and the duodenum equally. These data indicate that in the prairie dog, both motilin and cholecystokinin stimulate sphincter of Oddi and duodenal motility.

Sign in / Sign up

Export Citation Format

Share Document