Prevalence of Salivary Gland Neoplasms in the Head and Neck in Educational Hospitals in Cairo Governorate (Retrospective Cross Sectional Study) v1 (protocols.io.67ahhie)

protocols.io ◽  
2019 ◽  
Author(s):  
wegdan sayed
2017 ◽  
Vol 27 (2) ◽  
pp. 556-562 ◽  
Author(s):  
Kanako Ichikura ◽  
Aya Yamashita ◽  
Taro Sugimoto ◽  
Seiji Kishimoto ◽  
Eisuke Matsushima

2015 ◽  
Vol 30 (6) ◽  
pp. 599-605 ◽  
Author(s):  
Adam R. Aluisio ◽  
Annelies De Wulf ◽  
Ambert Louis ◽  
Christina Bloem

AbstractIntroductionMore than 90% of traumatic morbidity and mortality occurs in low- and middle-income countries (LMIC). Haiti is the poorest country in the Western Hemisphere and lacks contemporary statistics on the epidemiology of traumatic injuries. This study aimed to characterize the burden of traumatic injuries among emergency department patients in the Northeast region of Haiti.MethodsData were collected from the emergency departments of all public hospitals in the Northeast region of Haiti, which included the Fort Liberté, Ouanaminthe, and Trou du Nord sites. All patients presenting for emergent care of traumatic injuries were included. Data were obtained via review of emergency department registries and patient records from October 1, 2013 through November 30, 2013. Data on demographics, mechanisms of trauma, and anatomical regions of injury were gathered using a standardized tool and analyzed using descriptive statistics. Temporal analysis of injury frequency was explored using regression modeling.ResultsData from 383 patient encounters were accrued. Ouanaminthe Hospital treated the majority of emergent injuries (59.3%), followed by Fort Liberté (30.3%) and Trou du Nord (10.4%). The median age in years was 23 with 23.1% of patients being less than 15 years of age. Road traffic accidents (RTAs) and interpersonal violence accounted for 65.8% and 30.1% of all traumatic mechanisms, respectively. Extremity trauma was the most frequently observed anatomical region of injury (38.9%), followed by head and neck (30.3%) and facial (19.1%) injuries. Trauma due to RTA resulted in a single injury (83.8%) to either an extremity or the head and neck regions most frequently. A minority of patients had medical record documentation (37.9%). Blood pressure, respiratory rate, and mental status were documented in 19.3%, 4.1%, and 0.0% of records, respectively. There were 6.3 injuries/day during the data collection period with no correlation between the frequency of emergent trauma cases and day of the week (R^2=0.01).ConclusionsTraumatic injuries are a common emergent presentation in the Northeast region of Haiti with characteristics similar to other LMIC. Documentation and associated data to adequately characterize the burden of disease in this region are lacking. Road traffic accidents are the predominate mechanism of injury, suggesting that interventions addressing prevention and treatment of this common occurrence may provide public health benefits in this setting.AluisioAR,De WulfA,LouisA,BloemC.Epidemiology of traumatic injuries in the Northeast region of Haiti: a cross-sectional study.Prehosp Disaster Med.2015;30(6):599–605.


2020 ◽  
Vol 58 (229) ◽  
Author(s):  
Bigyan Raj Gyawali ◽  
Kunjan Acharya ◽  
Ravindra Sapkota ◽  
Dharma Kanta Baskota ◽  
Bimal Kumar Sinha

Introduction: P16 overexpression is considered as a good prognostic marker for oropharyngeal squamous cell carcinoma. However, there are very few literatures on the prevalence and outcomes of p16 overexpression in non-oropharyngeal squamous cell carcinoma and benign head and neck tumors. The aim of our study was to estimate the hospital based prevalence of p16 positive laryngeal and pharyngeal tumors and to compare it with the prevalence of p16 expression in the non tumor tissue (tonsils). Methods: This was a descriptive cross-sectional study. Cases of all genders >15 years presenting with malignant or benign tumors of larynx and all the subsites of pharynx were included in the study for evaluation of p16 expression by immunohistochemistry. Tonsillar tissue of cases undergoing tonsillectomy for recurrent acute tonsillitis were taken as non-tumorous tissue to evaluate for p16 expression. Results: A total of 48 cases were included in our study with 24 cases having different tumors of head and neck region and 24 cases having recurrent acute tonsillitis who were kept under non-tumor group. Eight cases (33.3%) in the tumor group showed positive stain for p16 in IHC. In non tumor group, 7 cases (29.1%) showed positive IHC staining for p16. Conclusions: P16 expression can be present in both benign and malignant tumors of various subsites of head and neck region and also in tonsillar tissue affected by inflammation.    


2021 ◽  
pp. 1-8
Author(s):  
Obed Solís-Martínez ◽  
Karolina Álvarez-Altamirano ◽  
Diana Cardenas ◽  
Yanelly Trujillo-Cabrera ◽  
Vanessa Fuchs-Tarlovsky

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e029084 ◽  
Author(s):  
Nida Zahid ◽  
Wardah Khalid ◽  
Khabir Ahmad ◽  
Shireen Shehzad Bhamani ◽  
Iqbal Azam ◽  
...  

BackgroundCancer is a devastating disease and has detrimental effects on the quality of life (QoL) of cancer survivors and interferes with their treatment compliance. The aim of the study is to assess resilience and QoL among cancer survivors and to evaluate the important factors affecting their resilience and QoL, with respect to the Pakistani cultural context.Method and analysisA cross-sectional study will be conducted at a tertiary care hospital in Karachi, Pakistan. A minimum sample size of 250 head and neck cancers and 250 brain tumour survivors with 10% inflation for non-response rate will be required. The SD of QoL and resilience will range from 16.5 to 40.8 for head and neck cancer, and 12.7 to 34.1 for brain tumour, at 5% level of significance, with 2.5 precision. QoL will be assessed by European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30, EORTC QLQ-H&N35 and EORTC QLQ-BN20 and resilience will be evaluated by Wagnild and Young’s 14-item scale. Mean±SD will be reported for resilience and QoL scores. Unadjusted and adjusted β-coefficients, with 95% CI, will be reported by using multiple linear regression analysis. Correlation analysis will also be performed using Pearson or Spearman rank correlation coefficients. A p value of <0.05 will be considered significant.Ethics and disseminationEthical approval has been obtained from the Aga Khan University Pakistan’s Ethical Review Committee. Written informed consent will be taken from the participants by trained research assistants. A trained psychologist will provide on-spot counselling to the participants and those identified with severe depression will be referred to a psychiatrist. The study materials will be kept under lock and key and the electronic data base will be password protected and will only be accessed by the research team. The study findings will be disseminated through publications conferences and workshops and research briefs.Trial registration numberClinicaltrials.gov registry (NCT03466762).


BMC Cancer ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Corinne Vannimenus ◽  
◽  
Hélène Bricout ◽  
Olivier Le Rouzic ◽  
François Mouawad ◽  
...  

2021 ◽  
Vol 11 (2) ◽  
pp. 215-218
Author(s):  
Manali Deb Barma ◽  
Meignana Arumugham Indiran ◽  
Pradeep Kumar R ◽  
Arthi Balasubramaniam ◽  
M.P Santhosh Kumar

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