Multi-layer Hybrid Classification Model of COVID-19 Chest X-ray Images v1

Author(s):  
Thanakorn Poomkur

The coronavirus disease of 2019(COVID-19) has been declared a pandemic and has raised worldwide concern. Lung inflammation and respiratory failure are commonly observed in moderate-to-severe cases. Radiography or chest X-ray imaging is compulsory for diagnosis, and interpretation is commonly performed by skilled medical specialists. In this study, we propose anew computer-aided diagnosis (CADx) tool for identifying chest X-ray images of COVID-19 infection using a multi-layer hybrid classification model (MLHC). The MLHC-COVID-19 consists of two layers, Layer I: Healthy and non-Healthy; Layer II: COVID-19 and non-COVID-19. The MLHC-COVID-19 was evaluated in real COVID-19 cases. The classification results showed promising performance comparable with other existing techniques considering the accuracy, sensitivity, and specificity of 96.20%, 96.20%, and 0.971%, respectively. This demonstrates the effectiveness of the MLHC-COVID-19 in classifying chest X-ray images, enhancing the accuracy of chest X-ray image interpretation with a reduction in the interpretation time. Furthermore, a detailed comparison of the MLHC-COVID-19 with other techniques has been presented.

2020 ◽  
Author(s):  
Mundher Taresh ◽  
Ningbo Zhu ◽  
Talal Ahmed Ali Ali

AbstractNovel coronavirus pneumonia (COVID-19) is a contagious disease that has already caused thousands of deaths and infected millions of people worldwide. Thus, all technological gadgets that allow the fast detection of COVID-19 infection with high accuracy can offer help to healthcare professionals. This study is purposed to explore the effectiveness of artificial intelligence (AI) in the rapid and reliable detection of COVID-19 based on chest X-ray imaging. In this study, reliable pre-trained deep learning algorithms were applied to achieve the automatic detection of COVID-19-induced pneumonia from digital chest X-ray images.Moreover, the study aims to evaluate the performance of advanced neural architectures proposed for the classification of medical images over recent years. The data set used in the experiments involves 274 COVID-19 cases, 380 viral pneumonia, and 380 healthy cases, which was collected from the available X-ray images on public medical repositories. The confusion matrix provided a basis for testing the post-classification model. Furthermore, an open-source library PyCM* was used to support the statistical parameters. The study revealed the superiority of Model VGG16 over other models applied to conduct this research where the model performed best in terms of overall scores and based-class scores. According to the research results, deep learning with X-ray imaging is useful in the collection of critical biological markers associated with COVID-19 infection. The technique is conducive for the physicians to make a diagnosis of COVID-19 infection. Meanwhile, the high accuracy of this computer-aided diagnostic tool can significantly improve the speed and accuracy of COVID-19 diagnosis.


2021 ◽  
Author(s):  
Thanakorn Poomkur ◽  
Thakerng Wongsirichot

The coronavirus disease of 2019 (COVID-19) has been declared a pandemic and has raised worldwide concern. Lung inflammation and respiratory failure are commonly observed in moderate-to-severe cases. Chest X-ray imaging is compulsory for diagnosis, and interpretation is commonly performed by skilled medical specialists. Many studies have been conducted using machine learning approaches such as Deep Learning (DL) with acceptable accuracy. However, other dimensions such as computational time were less discussed. Thus, our work is motivated to design anew computer-aided diagnosis (CADx) tool for identifying chest X-ray images of COVID-19 infection using machine learning techniques including Decision Tree (DT), Support Vector Machine (SVM), and Neural Networks (NNs). Our work is designed with the concept of multi-layer classification architecture and performs with minimal computational time and acceptable classification results. First, image segmentation, image enhancement and feature extraction techniques are performed. Second, machine learning techniques are selected based on classification performance. Finally, selected machine learning techniques are assembled into a multi-layer hybrid classification model for COVID-19 (MLHC-COVID-19). Specifically, the MLHC-COVID-19 consists of two layers, Layer I: Healthy and Unhealthy; Layer II: COVID-19 and non-COVID-19.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Aysen Degerli ◽  
Mete Ahishali ◽  
Mehmet Yamac ◽  
Serkan Kiranyaz ◽  
Muhammad E. H. Chowdhury ◽  
...  

AbstractComputer-aided diagnosis has become a necessity for accurate and immediate coronavirus disease 2019 (COVID-19) detection to aid treatment and prevent the spread of the virus. Numerous studies have proposed to use Deep Learning techniques for COVID-19 diagnosis. However, they have used very limited chest X-ray (CXR) image repositories for evaluation with a small number, a few hundreds, of COVID-19 samples. Moreover, these methods can neither localize nor grade the severity of COVID-19 infection. For this purpose, recent studies proposed to explore the activation maps of deep networks. However, they remain inaccurate for localizing the actual infestation making them unreliable for clinical use. This study proposes a novel method for the joint localization, severity grading, and detection of COVID-19 from CXR images by generating the so-called infection maps. To accomplish this, we have compiled the largest dataset with 119,316 CXR images including 2951 COVID-19 samples, where the annotation of the ground-truth segmentation masks is performed on CXRs by a novel collaborative human–machine approach. Furthermore, we publicly release the first CXR dataset with the ground-truth segmentation masks of the COVID-19 infected regions. A detailed set of experiments show that state-of-the-art segmentation networks can learn to localize COVID-19 infection with an F1-score of 83.20%, which is significantly superior to the activation maps created by the previous methods. Finally, the proposed approach achieved a COVID-19 detection performance with 94.96% sensitivity and 99.88% specificity.


2021 ◽  
Vol 29 (1) ◽  
pp. 19-36
Author(s):  
Çağín Polat ◽  
Onur Karaman ◽  
Ceren Karaman ◽  
Güney Korkmaz ◽  
Mehmet Can Balcı ◽  
...  

BACKGROUND: Chest X-ray imaging has been proved as a powerful diagnostic method to detect and diagnose COVID-19 cases due to its easy accessibility, lower cost and rapid imaging time. OBJECTIVE: This study aims to improve efficacy of screening COVID-19 infected patients using chest X-ray images with the help of a developed deep convolutional neural network model (CNN) entitled nCoV-NET. METHODS: To train and to evaluate the performance of the developed model, three datasets were collected from resources of “ChestX-ray14”, “COVID-19 image data collection”, and “Chest X-ray collection from Indiana University,” respectively. Overall, 299 COVID-19 pneumonia cases and 1,522 non-COVID 19 cases are involved in this study. To overcome the probable bias due to the unbalanced cases in two classes of the datasets, ResNet, DenseNet, and VGG architectures were re-trained in the fine-tuning stage of the process to distinguish COVID-19 classes using a transfer learning method. Lastly, the optimized final nCoV-NET model was applied to the testing dataset to verify the performance of the proposed model. RESULTS: Although the performance parameters of all re-trained architectures were determined close to each other, the final nCOV-NET model optimized by using DenseNet-161 architecture in the transfer learning stage exhibits the highest performance for classification of COVID-19 cases with the accuracy of 97.1 %. The Activation Mapping method was used to create activation maps that highlights the crucial areas of the radiograph to improve causality and intelligibility. CONCLUSION: This study demonstrated that the proposed CNN model called nCoV-NET can be utilized for reliably detecting COVID-19 cases using chest X-ray images to accelerate the triaging and save critical time for disease control as well as assisting the radiologist to validate their initial diagnosis.


2021 ◽  
Vol 11 (2) ◽  
pp. 411-424 ◽  
Author(s):  
José Daniel López-Cabrera ◽  
Rubén Orozco-Morales ◽  
Jorge Armando Portal-Diaz ◽  
Orlando Lovelle-Enríquez ◽  
Marlén Pérez-Díaz

2021 ◽  
Author(s):  
Ali Mohammad Alqudah ◽  
Shoroq Qazan ◽  
Ihssan S. Masad

Abstract BackgroundChest diseases are serious health problems that threaten the lives of people. The early and accurate diagnosis of such diseases is very crucial in the success of their treatment and cure. Pneumonia is one of the most widely occurred chest diseases responsible for a high percentage of deaths especially among children. So, detection and classification of pneumonia using the non-invasive chest x-ray imaging would have a great advantage of reducing the mortality rates.ResultsThe results showed that the best input image size in this framework was 64 64 based on comparison between different sizes. Using CNN as a deep features extractor and utilizing the 10-fold methodology the propose artificial intelligence framework achieved an accuracy of 94% for SVM and 93.9% for KNN, a sensitivity of 93.33% for SVM and 93.19% for KNN and a specificity of 96.68% for SVM and 96.60% for KNN.ConclusionsIn this study, an artificial intelligence framework has been proposed for the detection and classification of pneumonia based on chest x-ray imaging with different sizes of input images. The proposed methodology used CNN for features extraction that were fed to two different types of classifiers, namely, SVM and KNN; in addition to the SoftMax classifier which is the default CNN classifier. The proposed CNN has been trained, validated, and tested using a large dataset of chest x-ray images contains in total 5852 images.


Author(s):  
José Daniel López-Cabrera ◽  
Rubén Orozco-Morales ◽  
Jorge Armando Portal-Díaz ◽  
Orlando Lovelle-Enríquez ◽  
Marlén Pérez-Díaz

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