scholarly journals Association of folic acid and vitamin B12 deficiency in children with iron deficiency anaemia

2016 ◽  
Vol 3 (5) ◽  
pp. 358-363
Author(s):  
Dr Chithambaram Nagalingam Saroja ◽  
◽  
Dr Joy L P D’Souza ◽  
Keyword(s):  
Folic Acid ◽  
Iron Deficiency ◽  
Vitamin B12 ◽  
Iron Deficiency Anaemia ◽  
Vitamin B12 Deficiency ◽  
Deficiency Anaemia ◽  
B12 Deficiency

scholarly journals Prevalence of Folic Acid And Vitamin B12 Deficiency in Anemic Adolescents

2020 ◽  
Vol 11 (3) ◽  
pp. 4630-4635
Author(s):  
Mayank Jain ◽  
Girish Ganesh Joag ◽  
Kshirsagar V Y
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Health Concern ◽  
Folic Acid Deficiency ◽  
Cross Sectional ◽  
Female Ratio ◽  
Deficiency Anaemia ◽  
Acid Deficiency ◽  
B12 Deficiency

Adolescents may enjoy nourishment trends, macrobiotic weight control plans and semi-starvation regimens in calories, nutrients and minerals. Protein need in a juvenile for every unit body weight is higher than that of grown-up; however, not exactly a quickly developing newborn child. Adolescence has higher nutrient and mineral needs contrasted and individuals all things considered other life stages. A community-based cross-sectional study of 200 school going anaemic adolescents of age group 10 – 19 years. A predesigned semi-organized survey was readied dependent on the audit of writing on Adolescent iron deficiency. The study included 200 anaemic adolescents belonging to two schools, 89 were males, and 111 were females. Male: female ratio was 1.25:1. Among a total of 200 participants, 122 anaemic adolescents belonged to early adolescence. The mean age of anaemic adolescent participants of this study was 13.19 years with a standard deviation of 1.23. among the participants, 137 anaemic adolescents took a vegetarian diet, and 63 anaemic adolescents took a mixed diet. There were three participants underweight according to BMI classification, and 190 had normal range of BMI, 132 adolescents had moderate anaemia (Hb- 8.0 to 10.9 ). Majority of 66.5%(133/200) had Vitamin B12 deficiency anaemia, 72.5%(145/200) had folic acid deficiency anaemia, and 58.5% (117/200) had combined Vitamin B12 and folic acid deficiency anaemia. Prevalence of anaemia in adolescent is a significant public health concern. Supplementation with not only iron and folic acid but also Vitamin B12 may be need of the day. Besides supplementation adequate education regarding quality food, cooking practices and health education is also necessary to be emphasized in adolescents.

scholarly journals Assessing the Frequency, Investigation, and Management of Post-operative Anaemia in Hip Fracture Patients

2021 ◽  
Author(s):  
David Livingstone McCormack ◽  
Orla Costigan ◽  
Emily McGarry ◽  
Shane O’Hanlon ◽  
Conor Hurson
Keyword(s):  
Hip Fracture ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Vitamin B12 Deficiency ◽  
Folate Deficiency ◽  
University Hospital ◽  
Major Surgery ◽  
Deficiency Anaemia ◽  
Retrospective Audit ◽  
B12 Deficiency

Abstract BackgroundPost-operative anaemia affects up to 90% of patients undergoing major surgery [1]. Post-operative anaemia can contribute to slower rehabilitation, increased morbidity, and increased mortality [2]. AimsWe aimed to examine the frequency, investigation, and management of anaemia in patients admitted to St. Vincent’s University Hospital (SVUH) with a hip fracture.MethodsA retrospective audit, examining all patients who were admitted to SVUH with a hip fracture between the 1st of April and the 30th of June 2020, was performed. ResultsA total of 58 patients were included. Upon admission, 29.3% (n = 17) of patients were anaemic. Post-operatively, 91.4% of patients (n = 53) were anaemic. 43.1% (n = 25) of patients had iron studies, ferritin, folate and B12 levels measured. Iron deficiency anaemia was detected in 22.4% (n = 13) of patients, folate deficiency was detected in 10.3% (n = 6), and no patients were found to have vitamin B12 deficiency. Of the patients with iron deficiency anaemia, 15.4% (n = 2) were given IV iron infusions and 7.7% (n = 1) received a prescription for oral iron. Of the 6 patients with folate deficiency, 33.3% (n = 2) received a prescription for folic acid. Red cell transfusions were given to 13.8% (n = 8) of patients. Upon discharge, 89.7% (n = 52) of patients remained anaemic. ConclusionsAnaemia is an under-investigated and under-treated complication of hip fractures.

scholarly journals ETIOLOGICAL PROFILE OF 50 CASES 0F ANAEMIA IN CKD

2020 ◽  
pp. 1-2
Author(s):  
Yalavarthi Hema Choudary ◽  
E. Karthik ◽  
Ch. Sudhakar
Keyword(s):  
Chronic Disease ◽  
Kidney Disease ◽  
Iron Deficiency ◽  
Clinical Examination ◽  
Iron Deficiency Anaemia ◽  
Vitamin B12 Deficiency ◽  
Deficiency Anaemia ◽  
Anaemia Of Chronic Disease ◽  
B12 Deficiency ◽  
Erythropoietin Deficiency

Background and objectives: Anaemia is a common and significant complication of chronic kidney disease (CKD). When present it may cause symptoms such as fatigue and shortness of breath. It is associated with reduced quality of life and increased cardiovascular disease, hospitalizations, cognitive impairment and mortality. As kidney disease progresses, anaemia increases in prevalence affecting nearly all patients with stage V CKD. In patients with CKD, anaemia is defined as the situation in which the concentration of haemoglobin (Hb) in the blood is below 2 times the SD of the mean Hb of the general population. As the pathogenesis of anaemia in CKD is mutlifactorial, this study is intended to know various etiological factors responsible for anaemia in CKD patients. Methods: 50 patients who met with inclusion criteria and exclusion criteria are subjected to detail clinical examination and investigations. Depending upon data obtained, results are evaluated and the percentage of various types of anaemia in CKD was calculated. Results: At the end of study, anaemia of chronic disease (60%) constitutes the commonest cause of anaemia in CKD, followed by iron deficiency anaemia (30%) and megaloblastic anaemia (10%) due to vitamin B12 deficiency. Conclusion: Among 50 cases of anaemia in CKD, anaemia of chronic disease due to erythropoietin deficiency was the most common cause followed by iron deficiency anaemia. Usually clinical examination and routine simple investigations will clinch the diagnosis in most of the cases.

Population-Based Prevalence of Anemia, Iron, Folic Acid and Vitamin B12 Deficiency among Young Adults in Israel.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 3754-3754
Author(s):  
Drorit Merkel ◽  
Ran Balicer ◽  
Nadav Davidovitch ◽  
Itamar Grotto ◽  
Salman Zarka ◽  
...  
Keyword(s):  
Young Adults ◽  
Folic Acid ◽  
Iron Deficiency ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Paternal Education ◽  
B12 Deficiency ◽  
Iron Folic Acid ◽  
Education And Immigration ◽  
Prevalence Of Anemia

Abstract Background: The prevalence of anemia and iron deficiency among adolescents and young adults in Israel has not yet been assessed. Studies performed among specific populations in Israel demonstrated highly variable rates of anemia of 6–58%, with iron deficiency rates of 13–38%. We have set out to investigate the prevalence of anemia, iron, folic acid and vitamin B12 deficiency among young males and females that are requited to the army in Israel (IDF). Methods: A random sample of 366 new recruits to the IDF (270 males and 96 females) participated in the study and undergone blood testing for Hemoglobin, Iron, Transferrin, Ferritin, Vitamin B12, Folic acid on recruitment day. Results: Anemia among females (Hb<12 gr/dl), was 15.1% compared with 11.4% among males (Hb<14 gr/dl). Transferrin saturation values indicating iron deficiency (15%>) were also more prevalent among females compared with males (28.1% and 9.7%, respectively), as were low ferritin rates (37.2% and 14.3%, respectively). Vitamin B-12 deficiency (<180 pg/ml) was found in 6.6–9.6% of the subjects, and folic acid deficiency was detected in 6.4–11.7% of the subjects. Low-level paternal education and immigration were two factors found to be negatively associated with anemia. Smoking was associated with low ferritin levels in males. Anemia and iron levels were not affected significantly by the type of service designed, as combat soldiers or for clerical work. Conclusions: Anemia and iron deficiency occur frequently among young adults requited to the IDF. They were more prevalent among females; but in males the prevalence is higher than expected. Low content of iron in the diet, infection like H Pylori and engaging in strenuous exercise preparing to service, may contribute to depleted iron stores. Low-level paternal education and immigration was surprisingly protecting factor, may be as a result of different eating habits. Anemia and iron deficiency, are known to reduce physical work capacity and mental performance, therefore it is important to perform more research to identify possible etiologies for intervention like education for proper nutrition, and adjustment of the diet in the military to tackle this prevalent problem.

scholarly journals Prevalence of Iron, Folic Acid and Vitamin B12 Deficiency in Patients with Thalassemia Minor

2013 ◽  
Vol 7 (4) ◽  
pp. 83 ◽  
Author(s):  
Suheyl Asma ◽  
Cigdem Gereklioglu ◽  
Ahmet Erdogan ◽  
Mahmut Yeral ◽  
Mutlu Kasar ◽  
...  
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Thalassemia Minor ◽  
B12 Deficiency ◽  
Iron Folic Acid

Brief Report: Observations on Conjugated and Unconjugated Blood Folate Levels in Megaloblastic Anemia and the Effects of Vitamin B12

Blood ◽  
1965 ◽  
Vol 26 (3) ◽  
pp. 354-359 ◽  
Author(s):  
K. N. JEEJEEBHOY ◽  
S. M. PATHARE ◽  
J. M. NORONHA
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Megaloblastic Anemia ◽  
Vitamin B12 Deficiency ◽  
Cellular Level ◽  
B12 Deficiency

Abstract Vitamin B12 deficiency was associated with a rise in unconjugated folates and marked depletion of intracellular conjugated folates. The changes could be reversed by giving vitamin B12. These results probably indicate a way by which vitamin B12 and folic acid are interrelated at the cellular level.

scholarly journals Iron deficiency anemia and megaloblastic anemia in obese patients

2017 ◽  
Vol 55 (1) ◽  
pp. 3-7 ◽  
Author(s):  
Mahmoud Arshad ◽  
Sara Jaberian ◽  
Abdolreza Pazouki ◽  
Sajedeh Riazi ◽  
Maryam Aghababa Rangraz ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Morbid Obesity ◽  
Iron Deficiency ◽  
Vitamin B12 ◽  
Iron Deficiency Anemia ◽  
Megaloblastic Anemia ◽  
Vitamin B12 Deficiency ◽  
Deficiency Anemia ◽  
Obese Patients ◽  
B12 Deficiency

Abstract Background. The association between obesity and different types of anemia remained uncertain. The present study aimed to assess the relation between obesity parameters and the occurrence of iron deficiency anemia and also megaloblastic anemia among Iranian population. Methods and Materials. This cross-sectional study was performed on 1252 patients with morbid obesity that randomly selected from all patients referred to Clinic of obesity at Rasoul-e-Akram Hospital in 2014. The morbid obesity was defined according to the guideline as body mass index (BMI) equal to or higher than 40 kg/m2. Various laboratory parameters including serum levels of hemoglobin, iron, ferritin, folic acid, and vitamin B12 were assessed using the standard laboratory techniques. Results. BMI was adversely associated with serum vitamin B12, but not associated with other hematologic parameters. The overall prevalence of iron deficiency anemia was 9.8%. The prevalence of iron deficiency anemia was independent to patients’ age and also to body mass index. The prevalence of vitamin B12 deficiency was totally 20.9%. According to the multivariable logistic regression model, no association was revealed between BMI and the occurrence of iron deficiency anemia adjusting gender and age. A similar regression model showed that higher BMI could predict occurrence of vitamin B12 deficiency in morbid obese patients. Conclusion. Although iron deficiency is a common finding among obese patients, vitamin B12 deficiency is more frequent so about one-fifth of these patients suffer vitamin B12 deficiency. In fact, the exacerbation of obesity can result in exacerbation of vitamin B12 deficiency.

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