Population-Based Prevalence of Anemia, Iron, Folic Acid and Vitamin B12 Deficiency among Young Adults in Israel.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 3754-3754
Author(s):  
Drorit Merkel ◽  
Ran Balicer ◽  
Nadav Davidovitch ◽  
Itamar Grotto ◽  
Salman Zarka ◽  
...  

Abstract Background: The prevalence of anemia and iron deficiency among adolescents and young adults in Israel has not yet been assessed. Studies performed among specific populations in Israel demonstrated highly variable rates of anemia of 6–58%, with iron deficiency rates of 13–38%. We have set out to investigate the prevalence of anemia, iron, folic acid and vitamin B12 deficiency among young males and females that are requited to the army in Israel (IDF). Methods: A random sample of 366 new recruits to the IDF (270 males and 96 females) participated in the study and undergone blood testing for Hemoglobin, Iron, Transferrin, Ferritin, Vitamin B12, Folic acid on recruitment day. Results: Anemia among females (Hb<12 gr/dl), was 15.1% compared with 11.4% among males (Hb<14 gr/dl). Transferrin saturation values indicating iron deficiency (15%>) were also more prevalent among females compared with males (28.1% and 9.7%, respectively), as were low ferritin rates (37.2% and 14.3%, respectively). Vitamin B-12 deficiency (<180 pg/ml) was found in 6.6–9.6% of the subjects, and folic acid deficiency was detected in 6.4–11.7% of the subjects. Low-level paternal education and immigration were two factors found to be negatively associated with anemia. Smoking was associated with low ferritin levels in males. Anemia and iron levels were not affected significantly by the type of service designed, as combat soldiers or for clerical work. Conclusions: Anemia and iron deficiency occur frequently among young adults requited to the IDF. They were more prevalent among females; but in males the prevalence is higher than expected. Low content of iron in the diet, infection like H Pylori and engaging in strenuous exercise preparing to service, may contribute to depleted iron stores. Low-level paternal education and immigration was surprisingly protecting factor, may be as a result of different eating habits. Anemia and iron deficiency, are known to reduce physical work capacity and mental performance, therefore it is important to perform more research to identify possible etiologies for intervention like education for proper nutrition, and adjustment of the diet in the military to tackle this prevalent problem.

2013 ◽  
Vol 7 (4) ◽  
pp. 83 ◽  
Author(s):  
Suheyl Asma ◽  
Cigdem Gereklioglu ◽  
Ahmet Erdogan ◽  
Mahmut Yeral ◽  
Mutlu Kasar ◽  
...  

Blood ◽  
2021 ◽  
Vol 138 (Supplement 1) ◽  
pp. 4158-4158
Author(s):  
Riya Bansal ◽  
Aaron Frank ◽  
Anna Aledia ◽  
Drew Park ◽  
Smeet Madhani ◽  
...  

Abstract Introduction Anemia, including Iron Deficiency Anemia (IDA), is a prevalent public health crisis around the world. In IDA, red blood cells are unable to oxygenate tissues in the body due to the lack of essential iron. India has had a particularly high consistent prevalence of IDA since the National Family Health Survey began in 1991. Other forms of anemia can arise due to a lack of vitamin B12, folic acid, and other micronutrients that make up hemoglobin, the oxygen-carrying in red blood molecules. The villages of Dhank, Kolki, and Bhimora in the state of Gujarat, India have not been focused on in great depth for the prevalence and severity of anemia. Researchers sought to understand the prevalence of anemia in rural areas from a public health standpoint. Understanding the prevalence of anemia in specific regions in India is imperative to identifying where to focus therapies that target iron deficiency and other causes of anemia, such as through the administration of iron, folic acid, vitamin B12, vitamin C, and deworming medications. Methods and Materials Blood samples were taken to measure hemoglobin levels (g/dl) utilizing the glucometer device from two samples: boys and girls ages 0-18, and women ages 18-45 in the villages of Dhank, Kolki, and Bhimora villages in the state of Gujarat. Sample sizes were n=17,111 children and n=9,151 women. Researchers at the University of California, Irvine School of Medicine teamed up with the public health research team to statistically analyze hemoglobin level data, understanding prevalence of anemia in in the three villages. Researchers calculated the prevalence of anemia in both groups based on World Health Organization (WHO) criteria. Results The results show levels of moderate and severe anemia within the states of Kolki, Bhimora, and Dhank for children aged 0-18 and women aged 18-45. In the children group, the highest level of "moderate" to "severe anemia" was in Bhimora. The lowest level of "severe anemia" and highest level of "no anemia" were in Kolki. Similar results were seen in the women's group. In the women's group, the highest level of "moderate" and "severe anemia" were in Bhimora. The lowest level of "severe anemia" and highest level of "no anemia" were in Kolki. Conclusion Anemia is a serious public health crisis within the state of Gujarat, specifically in the villages of Kolki, Bhimora, and Dhank for children 0-18 and women 18-45, as indicated by the high prevalence of moderate and severe anemia in these areas. These findings call for interventions to combat this public health issue. Future study of the data will show which specific socioeconomic factors (caste, class, working status, etc.) are associated with lower hemoglobin levels. These future studies, in turn, will guide the targeted deployment of iron, folic acid, vitamin B12, vitamin C, and deworming tablets along with extensive educational intervention. Figure 1 Figure 1. Disclosures No relevant conflicts of interest to declare.


2021 ◽  
Vol 104 (2) ◽  
pp. 003685042110076
Author(s):  
Nazmi Mutlu Karakaş

Background: In this study, the aim was to evaluate the prevalence of vitamin D, vitamin B12, ferritin, and folate deficiencies in adolescence to clarify the need for early diagnosis and therapy. Methods: The medical records of adolescents between 10 and 18 years of age between 01 September 2018 and 28 February 2019 as healthy with non-specific complaints, or due to well-child care visits, were analyzed retrospectively. Results: A total of 1847/2507 (73.6%) adolescents were included in the study. The prevalence of vitamin D deficiency was 25.7% (n: 178/691). Vitamin B12 deficiency prevalence was 69.2% (n: 753/1088). The prevalence of anemia and ferritin deficiency was 4.8% and 13.26%. The prevalence of folate deficiency was 37.9% (n: 413/1088). VDD prevalence was statistically significantly higher in females than males (F/M:116/62). VB12D prevalence, the number and mean age of females with hemoglobin deficiency, and low ferritin levels was found to be statistically significantly higher in females than males. Conclusions: The prevalence of vitamin D, vitamin B12, folate deficiency and low ferritin levels was found to be high among adolescents. In particular, adolescents admitting with non-specific complaints and for control purposes in big cities must be considered to be at risk for the deficiency of these vitamins and low level of ferritin.


2021 ◽  
Vol 12 (2) ◽  
pp. 54-58
Author(s):  
Vinay Krishnamurthy ◽  
Akhila Rao Kerekoppa

Background: Diabetes is one of the largest global health emergencies of the 21st century. Prevalence of anemia in diabetic patients is two to three times higher than for patients with comparable renal impairment and iron stores in the general population. Aims and Objective: This study was done to analyse the prevalence of anemia and its profile in patients with preserved renal function. Materials and Methods: One-hundred diabetic patients with anemia with normal renal functions were selected. Complete blood count, peripheral blood smear, iron studies, vitamin B12 levels were assessed. Diabetic control was monitored by HbA1c. Patients were identified to have specific type of anemia, based on iron profile and vitamin B12 levels. Severity of anemia was also assessed. Appropriate statistical tests were applied to analyse the results. Results: Mean age of subjects in the study group was 53.4±13.6 years. The mean haemoglobin level was 9.41±2.18 g/dl. Out of the 100 cases, 43 patients had iron deficiency anemia, 40 patients had anemia of inflammation, and 8 patients had vitamin B12 deficiency, 8 patients had combined iron and vitamin B12 deficiency, and 1 patient had pancytopenia. Mean HbA1c was higher in iron deficient individuals with a significant p value and mean HbA1c was lower in Vitamin B12 deficient individuals. Among the cases, 16% had mild anemia, 61% had moderate anemia, and 23% had severe anemia. Severe anemia had a significantly lower HbA1c, which was statistically significant. Conclusion: According to our study, iron deficiency anemia was the commonest, followed by anemia of inflammation in diabetic patients with preserved renal function. Diabetes being a pro-inflammatory state had a higher incidence of anemia of inflammation compared to general population. We have to identify and acknowledge the higher prevalence of Anemia of Inflammation in diabetic patients in the absence of renal dysfunction.


Blood ◽  
1965 ◽  
Vol 26 (3) ◽  
pp. 354-359 ◽  
Author(s):  
K. N. JEEJEEBHOY ◽  
S. M. PATHARE ◽  
J. M. NORONHA

Abstract Vitamin B12 deficiency was associated with a rise in unconjugated folates and marked depletion of intracellular conjugated folates. The changes could be reversed by giving vitamin B12. These results probably indicate a way by which vitamin B12 and folic acid are interrelated at the cellular level.


2017 ◽  
Vol 55 (1) ◽  
pp. 3-7 ◽  
Author(s):  
Mahmoud Arshad ◽  
Sara Jaberian ◽  
Abdolreza Pazouki ◽  
Sajedeh Riazi ◽  
Maryam Aghababa Rangraz ◽  
...  

Abstract Background. The association between obesity and different types of anemia remained uncertain. The present study aimed to assess the relation between obesity parameters and the occurrence of iron deficiency anemia and also megaloblastic anemia among Iranian population. Methods and Materials. This cross-sectional study was performed on 1252 patients with morbid obesity that randomly selected from all patients referred to Clinic of obesity at Rasoul-e-Akram Hospital in 2014. The morbid obesity was defined according to the guideline as body mass index (BMI) equal to or higher than 40 kg/m2. Various laboratory parameters including serum levels of hemoglobin, iron, ferritin, folic acid, and vitamin B12 were assessed using the standard laboratory techniques. Results. BMI was adversely associated with serum vitamin B12, but not associated with other hematologic parameters. The overall prevalence of iron deficiency anemia was 9.8%. The prevalence of iron deficiency anemia was independent to patients’ age and also to body mass index. The prevalence of vitamin B12 deficiency was totally 20.9%. According to the multivariable logistic regression model, no association was revealed between BMI and the occurrence of iron deficiency anemia adjusting gender and age. A similar regression model showed that higher BMI could predict occurrence of vitamin B12 deficiency in morbid obese patients. Conclusion. Although iron deficiency is a common finding among obese patients, vitamin B12 deficiency is more frequent so about one-fifth of these patients suffer vitamin B12 deficiency. In fact, the exacerbation of obesity can result in exacerbation of vitamin B12 deficiency.


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