scholarly journals Application of improved percutaneous cystolithotripsy in patients with benign prostatic hyperplasia

2021 ◽  
Vol 22 (4) ◽  
pp. 54-59
Author(s):  
T. Kh. Nazarov ◽  
I. V. Rychkov ◽  
V. A. Nikolaev ◽  
K. E. Trubnikova

Introduction. The article presents an improved method of percutaneous cystolithotripsy. The results of its application are described and a comparison is made with the traditional method of transurethral cystolithotripsy with lithoextraction. The study objective is development of a comprehensive method of treating patients with bladder stones arising against the background of bladder outlet obstruction caused by benign prostatic hyperplasia (BPH), assessment of its effectiveness and safety.Materials and methods. The treatment was carried out in 56 patients with bladder stones arising on the background of BPH at the age from 42 to 89 years. According to the proposed method, 20 patients with BPH (main group) were operated on. Transurethral cystolithotripsy (control group) was performed in 36 patients. The results of the performed operations were compared with each other.Results. According to the comparison results, it is noted that the proposed method of percutaneous cystolithotripsy is performed faster and more efficiently, due to the fixation of the calculus in the basket. Due to the presence of a laparoscopic bag that completely isolates the stone from the bladder wall, there were no intraoperative complications. Drug therapy made it possible to quickly level the symptoms of cystitis. The patients were discharged 4-6 days after surgery with a cystostomy, which was removed after treatment for BPH.Conclusion. The proposed complex treatment of patients with bladder stones on the background of BPH is a safe method and has clear advantages over traditional transurethral, contact cystolithotripsy with lithoextraction.

2021 ◽  
pp. 5-9
Author(s):  
Prasenjit Bhowmik ◽  
Soumendranath Mandal ◽  
Gaurav Sharma ◽  
Bandhan Bahal ◽  
Prashant Gupta ◽  
...  

Objectives: To dene the diagnostic accuracy of intravesical protrusion of prostate (IPP), bladder wall thickness (BWT) and prostate volume (PV) in diagnosis of bladder outlet obstruction (BOO) and prediction of future acute urinary retention (AUR). A prospective Materials and methods: study of 127 patients, presenting with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH) were enrolled with 50 patients among them manifesting AUR. 35 normal persons were selected as control group. After inclusion, all patients underwent transabdominal ultrasound and pressure ow urodynamic study (UDS). UDS parameter, BOO index (BOOI) were used as a reference standard for stratifying the patients into two groups, BOO and non-BOO. The sono-morphological parameters, IPP, BWT and PV were used to compare between these two groups with calculating the diagnostic accuracy for each individual index. IPP, BWT Results: and PV had statistically signicant difference between group 1 (BOOI < 40) and 2 ( BOOI > 40) with strong correlation with BOOI. The Pearson's correlation coefcient (r) for IPP, BWT and PV were 0.762, 0.702 and 0.660 respectively. The AUC for IPP, BWT and PV were 0.824, 0.786 and 0.650 with highest accuracy for IPP (79.2%) at cutoff value of 7 mm. Using the same threshold value, IPP had higher statistical difference than BWT in predicting AUR with similar diagnostic accuracy of IPP and BWT together. IPP and BWT in conjunction with PV in place Conclusions: of UDS had good clinical utility in diagnosis of BOO due to BPH and future AUR prediction.


1996 ◽  
Vol 63 (3) ◽  
pp. 346-350
Author(s):  
A. Botturi ◽  
C. Simeone ◽  
G. Pezzotti ◽  
S. Cosciani Cunico

IPSS has a recognised utility in quantifying the symptoms of outlet obstruction, even if its specificity for benign prostatic hyperplasia has not been proved. Uroflowmetry can also define micturition patterns, but not the degree of obstruction. We correlated the symptom scores and the uroflowmetrograms in the screening of outlet obstruction. A group of 121 patients was evaluated: 111 subjects were observed for voiding symptoms and 10 normal patients were included as a control group. Qmax, IPSS and three new parameters suggested by Nishimoto and coll. (Qmax/T100, TQmax/T100, VV/T100 x Qmax) were considered for all patients. All the values, calculated for each patient, were correlated using Student's T test. A statistically significant correlation between IPSS and Nishimoto's parameters was observed when the latter were indicative of an abnormal flow.


2021 ◽  
Vol 21 (4) ◽  
pp. 47-53
Author(s):  
G. E. Roitberg ◽  
K. G. Mkrtchyan ◽  
N. G. Kulchenko

Background. The etiology of benign prostatic hyperplasia (BPH) has not been fully studied. The main role in the induction of prostate tissue proliferation is assigned to the metabolism of testosterone. Recently, it has been reported that one of the risk factors for BPH is a chronic violation of the blood supply to the prostate.The study objective is to determine the level of reproductive hormones in blood serum and prostate tissue when creating a model of chronic ischemia.Materials and methods. The model of chronic pelvic ischemia was created in 10 white non-linear mature rats by partial ligation of the inferior vena cava. The control group of the study consisted of 10 male rats of the same age. After 1.5 months, we performed a hormonal study in all rats (n = 20) determining the concentration of testosterone, dihydrotestosterone and estradiol in the blood and prostate tissue. Also, in all animals (n = 20), a morphological study of the prostate was performed.Results. We’ve found a significant increase in prostate mass in the main group of rats by 16.4 % (p <0.05). Animals with BPH and impaired blood supply to the prostate had changes in their hormonal status: increased levels of testosterone (p <0.05) and dihydrotestosterone (p >0.05) in the prostate tissue.Conclusion. Long-term ischemic disorders in the prostate may be a trigger factor for the development of BPH due to an increase in the concentration of testosterone.


2018 ◽  
Vol 19 (4) ◽  
pp. 46-53
Author(s):  
A. B. Bat’ko

The study objectiveis to evaluate clinical effectiveness of a phytopharmaceutical Vialissil® for treatment of patients with benign prostatic hyperplasia (BPH) and erectile dysfunction.Materials and methods. At the multi-specialty clinic “Family Doctor” (Saint Petersburg) 34 patients aged from 55 to 67 years (mean age 59.6 + 0.7 years) with BPH and concomitant erectile dysfunction without the need for surgical intervention were examined. All patients received previously prescribed symptomatic therapy for BPH and erectile dysfunction (a-adrenoblockers and phosphodiesterase type 5 inhibitors on demand). The treatment group included 18 patients who additionally received Vialissil® as capsules once a day for 30 days. The remaining 16 patients were the control group.Results.After treatment, intensity of general symptoms decreased more in the treatment group than in the control group (by 10 and 4 points, respectively). After the course of therapy, erectile function improved in both groups but only in the treatment group these dynamics were statistically significant. An increase in testosterone level was statistically significant only after combination therapy with Vialissil® (by 16.5 %), and blood level of biologically accessible (active) testosterone increased twofold.Conclusion.Combination therapy for BPH and erectile dysfunction including administration of the Vialissil® phytopharmaceutical more effectively decreases disease intensity compared to standard therapy.


2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Navin Shrestha ◽  
Huanchun Hu ◽  
Le Zhou ◽  
Bo Wang

Benign prostatic hyperplasia, which can be abbreviated as prostatic hyperplasia, is a urinary system disease that has a high incidence in middle-aged and elderly male populations in China. The incidence of benign prostatic hyperplasia is increasing year by year. Patients with benign prostatic hyperplasia are prone to have bladder outlet obstruction, which in turn leads to an increase in residual urine volume in the bladder and impurities in the urine, such as upper urinary calculi that enter the bladder, urine crystals, various exfoliated cells, etc. If these substances stay in the bladder for a long time, stones in the bladder will be generated. Benign prostatic hyperplasia with bladder stones can severely obstruct the urinary tract, causing clinical symptoms such as urinary tract infections, urinary urgency, frequent urination, and dysuria. These symptoms seriously affects the physical and mental health of patients, leading to low levels of normal work and quality of life. With the development of medical technology, surgical treatment is commonly used in clinical practice. Among them, transurethral prostatectomy is widely used in clinical treatment, and has achieved good results.


2008 ◽  
Vol 54 (2) ◽  
pp. 419-426 ◽  
Author(s):  
Matthias Oelke ◽  
Joyce Baard ◽  
Hessel Wijkstra ◽  
Jean J. de la Rosette ◽  
Udo Jonas ◽  
...  

2020 ◽  
Vol 11 (2) ◽  
pp. 197-203 ◽  
Author(s):  
Amirreza Abedi ◽  
Mohammad Reza Razzaghi ◽  
Amirhossein Rahavian ◽  
Ebrahim Hazrati ◽  
Fereshte Aliakbari ◽  
...  

Several therapeutic approaches such as holmium laser enucleation of the prostate (HoLEP) have been introduced to relieve bladder outlet obstruction caused by benign prostatic hyperplasia (BPH). Compared with other techniques including the transurethral resection of the prostate (TURP) and simple open prostatectomy, HoLEP results in a shorter hospital stay and catheterization time and fewer blood loss and transfusions. HoLEP is a size-independent treatment option for BPH with average gland size from 36 g to 170 g. HoLEP is a safe procedure in patients receiving an anticoagulant and has no significant influence on the hemoglobin level. Also, HoLEP is an easy and safe technique in patients with a prior history of prostate surgery and a need for retreatment because of adenoma regrowth. The postoperative erectile dysfunction rate of patients treated with HoLEP is similar to TURP or open prostatectomy and about 77% of these patients experience loss of ejaculation. Patients with transitional zone volume less than 30 mL may suffer from persistent stress urinary incontinence following HoLEP so other surgical techniques like bipolar TURP are a good choice for these patients. In young patients, considering HoLEP with high prostate-specific antigen density and a negative standard template prostate biopsy, multiparametric MRI needs to be considered to exclude prostate cancer.


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