MODELING THE GLOBAL ENGINEERING PROCESS IN AEROSPACE ORGANIZATION

Recent work on the crystallisation of inorganic crystals under compressed monomolecular surfactant films has shown that two dimensional templates can be used to promote the oriented nucleation of solids. When a suitable long alkyl chain surfactant is cast on the crystallisation media a monodispersied population of crystals forms exclusively at the monolayer/solution interface. Each crystal is aligned with a specific crystallographic axis perpendicular to the plane of the monolayer suggesting that nucleation is facilitated by recognition events between the nascent inorganic solid and the organic template.For example, monolayers of the long alkyl chain surfactant, stearic acid will promote the oriented nucleation of the calcium carbonate polymorph, calcite, on the (100) face, whereas compressed monolayers of n-eicosyl sulphate will induce calcite nucleation on the (001) face, (Figure 1 & 2). An extensive program of research has confirmed the general principle that molecular recognition events at the interface (including electrostatic interactions, geometric homology, stereochemical complementarity) can be used to promote the crystal engineering process.

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Reliability and maintainability within the dynamic systems-engineering process

10.2514/6.1989-5047 ◽

1989 ◽

Author(s):

MICHAEL WISKERCHEN ◽

R. PITTMAN

Keyword(s):

Systems Engineering ◽

Dynamic Systems ◽

Engineering Process

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Perancangan dan Pembuatan Alat Bantu Meja Putar untuk Mesin Cnc 4 Axis

Jurnal Riset Teknologi Industri ◽

10.26578/jrti.v10i2.2568 ◽

2016 ◽

Vol 10 (2) ◽

pp. 162-171

Author(s):

Hafid Hafid ◽

Tatang Sutisna

Keyword(s):

Processing Time ◽

Rotary Table ◽

Engineering Process ◽

Cnc Machine ◽

Economical Analysis ◽

Machining Center ◽

Design And Manufacturing ◽

The Cost ◽

Productivity And Competitiveness

The design and manufacturing of the rotary table with the specification Ø 170 mm (6 inches) for CNC machine 4 axis has been done. The objective of manufacturing a rotary table is to increase the efficiency of CNC machine Hardford 4 axis to be above 80% in line machining center CV. IM’s workshop. The engineering methods was taken, consist of: working preparation, manufacturing of working drawing, engineering process, the manufacturing and testing. The prototype has been tested and operated, the resulting of increasing productivity of which were as follows: the process of assembling was increased to be 3 time ( before 1 time) and processing time for a specific case reduced from 5 hours to 3 hours, number of operators for the case of assembling the rotary reduced to 1 person (before 4 persons), safety and security become to be better. The results show increased efficiency of CNC machine Hardford, from under 50% to be above 80%. Based on the economical analysis obtained by the cost of good sold (C.G.S) of the rotary table is IDR 34.060.000. The results presented in this paper is expected to be case study for developing a business of the metal and engineering SMEs domestic to the effort of improving efficiency, quality, productivity and competitiveness in global market.ABSTRAKPerancangan dan pembuatan alat bantu meja putar (rotary table) dengan spesifikasi teknis Ø 170 mm (6 inci) untuk mesin CNC 4 axis telah dilakukan. Tujuan pembuatan rotary table adalah untuk meningkatkan efisiensi mesin CNC Hardford 4 axis di atas 80% pada line machining center Bengkel CV. IM. Metode rancang bangun yang dilakukan, meliputi: persiapan kerja, pembuatan gambar kerja, proses engineering, pembuatan dan uji coba. Prototip tersebut telah diuji coba dan dioperasikan dengan hasil peningkatan produktivitas sebagai berikut: proses pengerjaan bongkar pasang meningkat menjadi 3 kali (sebelumnya 1 kali) dan waktu pengerjaan untuk kasus tertentu berkurang dari 5 jam menjadi 3 jam, jumlah operator untuk kasus bongkar pasang rotary berkurang menjadi 1 orang (sebelumnya 4 orang), keselamatan kerja dan keamanan menjadi lebih baik. Hasil peningkatan berupa efisiensi mesin CNC Hardford 4 axis dari sebelumnya di bawah 50% menjadi di atas 80%. Berdasarkan hasil perhitungan analisis ekonomi diperoleh harga pokok produksi (HPP) alat bantu meja putar adalah sebesar Rp. 34.060.000. Bahasan ini diharapkan menjadi contoh kasus bagi pengembangan usaha IKM logam dan mesin dalam negeri untuk meningkatkan efisiensi, mutu, produktivitas dan keunggulan daya saing di pasar global.Kata kunci: alat bantu meja putar, mesin CNC, harga pokok produksi

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Journal of Chemical Engineering & Process Technology

10.35248/2157-7048 ◽

2020 ◽

Keyword(s):

Chemical Engineering ◽

Engineering Process ◽

Process Technology

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Affecting HEK293 Cell Growth and Production Performance by Modifying the Expression of Specific Genes

Cells ◽

10.3390/cells10071667 ◽

2021 ◽

Vol 10 (7) ◽

pp. 1667

Author(s):

Laura Abaandou ◽

David Quan ◽

Joseph Shiloach

Keyword(s):

Cell Line ◽

Cell Lines ◽

Hek293 Cell ◽

Chinese Hamster ◽

Production Performance ◽

Cellular Processes ◽

Hek293 Cell Line ◽

Global Engineering ◽

Genomic Tools ◽

Serum Free Suspension

The HEK293 cell line has earned its place as a producer of biotherapeutics. In addition to its ease of growth in serum-free suspension culture and its amenability to transfection, this cell line’s most important attribute is its human origin, which makes it suitable to produce biologics intended for human use. At the present time, the growth and production properties of the HEK293 cell line are inferior to those of non-human cell lines, such as the Chinese hamster ovary (CHO) and the murine myeloma NSO cell lines. However, the modification of genes involved in cellular processes, such as cell proliferation, apoptosis, metabolism, glycosylation, secretion, and protein folding, in addition to bioprocess, media, and vector optimization, have greatly improved the performance of this cell line. This review provides a comprehensive summary of important achievements in HEK293 cell line engineering and on the global engineering approaches and functional genomic tools that have been employed to identify relevant genes for targeted engineering.

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Information Quality Assessment for Data Fusion Systems

Data ◽

10.3390/data6060060 ◽

2021 ◽

Vol 6 (6) ◽

pp. 60

Author(s):

Miguel A. Becerra ◽

Catalina Tobón ◽

Andrés Eduardo Castro-Ospina ◽

Diego H. Peluffo-Ordóñez

Keyword(s):

Data Fusion ◽

Information Quality ◽

Engineering Process ◽

Comprehensive Description ◽

Research Issues ◽

Fusion Systems ◽

General Data ◽

Fusion Engineering ◽

And Performance ◽

Key Aspects

This paper provides a comprehensive description of the current literature on data fusion, with an emphasis on Information Quality (IQ) and performance evaluation. This literature review highlights recent studies that reveal existing gaps, the need to find a synergy between data fusion and IQ, several research issues, and the challenges and pitfalls in this field. First, the main models, frameworks, architectures, algorithms, solutions, problems, and requirements are analyzed. Second, a general data fusion engineering process is presented to show how complex it is to design a framework for a specific application. Third, an IQ approach, as well as the different methodologies and frameworks used to assess IQ in information systems are addressed; in addition, data fusion systems are presented along with their related criteria. Furthermore, information on the context in data fusion systems and its IQ assessment are discussed. Subsequently, the issue of data fusion systems’ performance is reviewed. Finally, some key aspects and concluding remarks are outlined, and some future lines of work are gathered.

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