Effectiveness, safety and assessing the results of drug therapy in patients with epilepsy

On June 26, 2021, a meeting of the experts of the Russian League Against Epilepsy (RLAE) was held, dedicated to the effectiveness, safety and assessing the results of drug therapy in patients with epilepsy. Having considered the history of the issue and guided by domestic and foreign experience, the participants discussed the problems associated with the use of various antiepileptic drugs for different forms of epilepsy in patients of different sex and age. Special attention was paid to psychiatric comorbidity in patients with epilepsy, increasing their compliance with treatment and quality of life. The article presents the Resolution of RLAE experts meeting adopted as a result of the discussion.

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QUALITY OF LIFE IN PATIENTS WITH CHRONIC VENOUS DISEASES AND METHODS OF ITS IMPROVEMENT (review)

Inter Collegas ◽

10.35339/ic.5.2.64-68 ◽

2018 ◽

Vol 5 (2) ◽

pp. 64-68

Author(s):

N. Pytetska

Keyword(s):

Quality Of Life ◽

Drug Therapy ◽

Work Capacity ◽

Modern Medicine ◽

Comprehensive Analysis ◽

New Methods ◽

Treatment And Prevention ◽

Venous Diseases ◽

History Of

QUALITY OF LIFE IN PATIENTS WITH CHRONIC VENOUS DISEASES AND METHODS OF ITS IMPROVEMENT (review)N.I. Pytetska Assessment of the quality of life is one of the leading directions in modern medicine and continues to develop intensively, remaining an integral part of comprehensive analysis of new methods of diagnosis, treatment and prevention. This article provides information about the history of the concept "quality of life" and the ambiguity of terminology. Particular attention is paid to the necessity of studying this indicator in patients with chronic veins diseases, the relevance of this direction in the early stages of the disease, as well as medicines able to solve the main tasks of drug therapy, to restore work capacity and, as a result improve the patient's life quality.Key words: quality of life, chronic venous diseases, diosmin. ЯКІСТЬ ЖИТТЯ ХВОРИХ НА ХРОНІЧНІ ЗАХВОРЮВАННЯ ВЕН ТА МЕТОДИ ЇЇ ПОКРАЩЕННЯ (огляд)Питецька Н.І.Вивчення якості життя є одним із провідних напрямків сучасної медицини й продовжує інтенсивно розвиватись, залишаючись невід'ємною частиною всебічного аналізу нових методів діагностики, лікування і профілактики. У даній статті представлено інформацію про історію виникнення поняття «якість життя», неоднозначність термінології. Особливуувагу приділено необхідності оцінки даного показника у хворих на хронічні захворювання вен, актуальності цього напрямку на ранніх стадіях захворювання, а також лікарським засобам, які здатні вирішувати основні завдання медикаментозної терапії, відновлювати працездатність і підвищувати якість життя пацієнта.Ключові слова: якість життя, хронічні захворювання вен, діосмін. КАЧЕСТВО ЖИЗНИ БОЛЬНЫХ С ХРОНИЧЕСКИМИ ЗАБОЛЕВАНИЯМИ ВЕН И МЕТОДЫ ЕГО УЛУЧШЕНИЯ (обзор)Питецкая Н.И.Изучение качества жизни является одним из ведущих направлений современной медицины и продолжает интенсивно развиваться, оставаясь неотъемлемой частью всестороннего анализа новых методов диагностики, лечения и профилактики. В данной статье представлена информация об истории возникновения понятия «качество жизни», неоднозначности терминологии. Особое внимание уделено необходимости оценки данного показателя у больных хроническими заболеванияи вен, актуальности этого направления на ранних стадиях заболевания, а также лекарственным препаратам, которые способны решать основные задачи медикаментозной терапии, восстанавливать трудоспособность и повышать качество жизни пациента.Ключевые слова: качество жизни, хронические заболевания вен, диосмин.

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Psychiatric comorbidity and quality of life in patients with epilepsy on anti-epileptic monotherapy and polytherapy

Tzu Chi Medical Journal ◽

10.4103/tcmj.tcmj_34_21 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

Jagriti Yadav ◽

Priti Singh ◽

Surekha Dabla ◽

Rajiv Gupta

Keyword(s):

Quality Of Life ◽

Psychiatric Comorbidity ◽

Patients With Epilepsy

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Association of non-adherence to antiepileptic drugs and seizures, quality of life, and productivity: Survey of patients with epilepsy and physicians

Epilepsy & Behavior ◽

10.1016/j.yebeh.2008.03.009 ◽

2008 ◽

Vol 13 (2) ◽

pp. 316-322 ◽

Cited By ~ 127

Author(s):

Collin A. Hovinga ◽

Miya R. Asato ◽

Ranjani Manjunath ◽

James W. Wheless ◽

Stephanie J. Phelps ◽

...

Keyword(s):

Quality Of Life ◽

Antiepileptic Drugs ◽

Patients With Epilepsy

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Psychosocial Problems and Physical Activity at Different Ages in Patients with Epilepsy

Baltic Journal of Sport and Health Sciences ◽

10.33607/bjshs.v2i89.156 ◽

2018 ◽

Vol 2 (89) ◽

Author(s):

Elvyra Grinienė ◽

Viktorija Pečinina

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Antiepileptic Drugs ◽

Physical Inactivity ◽

Age Groups ◽

Psychosocial Problems ◽

Health Problems ◽

Activity Levels ◽

Patients With Epilepsy

Research background and hypothesis. Physical inactivity of patients with epilepsy is associated with the course of the disease, treatment, preconceived attitudes and myths that their physical activity might be dangerous and cause seizures (Steinhoff et al., 1996; Nakken, 2001 ).The aim of our research was to examine the links between the psychosocial problems of patients’ with epilepsy, their hysical activity, self-reported quality of life as well as their connection with patients’ age. Research methods. The participants were 209 patients with epilepsy from three different regions (Šiauliai, Panevėžys and Pasvalys) of Lithuania. The subjects were selected with the help of quantitative closed-type survey – QOLIE-89 and IPAQ international questionnaire. The research findings were compared between two age groups: younger (20–39 years of age) and senior (40–59 years of age) subjects. Research results. The main psychosocial problems for patients with epilepsy were concerns about possible injuries during the seizures, experience of shame and other social restraint, health problems that might occur as a result of taking antiepileptic drugs for a long period of time, negative effects of antiepileptic drugs and memory impairments. These problems were more common among younger respondents (p < 0.05). Physical activity levels in patients with epilepsy were inadequate and different. The main factor that contributed to these differences was patients’ age. Younger respondents trained more in their leisure time, while seniors spent more time reading or sleeping (p = 0.002).Younger patients lacked knowledge about the most appropriate types of physical activities, senior respondents were inactive were to the disapproval of medical professionals and their health problems (p = 0.006). Younger respondents evaluated their lifestyle as good enough more often than seniors. Discussion and conclusion. Psychosocial problems and physical inactivity of patients with epilepsy were connected with their age. Younger respondents more often than seniors were physically active and their self-reported quality of life was good.Keywords: age of patients with epilepsy, social problems, physical activity, evaluation of lifestyle.

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A review on cost effective analysis of antiepileptic drugs

International Journal of Bioassays ◽

10.21746/ijbio.2017.9.6 ◽

2017 ◽

Vol 6 (9) ◽

pp. 5507 ◽

Cited By ~ 1

Author(s):

Uthara S.S. ◽

Mohammed Basheer ◽

Anil Babu A.

Keyword(s):

Quality Of Life ◽

Developing Countries ◽

Antiepileptic Drugs ◽

Low Cost ◽

Cost Effective ◽

Global Burden ◽

Patients With Epilepsy ◽

Effective Analysis

80% of the epilepsy patients were resides in developing countries. 12 million patients with epilepsy were in India that is One-sixth of the global burden is due to epilepsy. Those diseases were treated properly there is a greater reduction in seizure and people may leads to proper life, if untreated that may become a large increase in burden. Drugs are the main treatment for epilepsy. As compared with conventional AEDs newer drugs are much expensive some newer drugs were 10 to 20 times costlier than older drugs. if those expensive drugs reduce the seizure events, improves the quality of life and with lesser ADRs then the benefit justify the higher cost of the drug. The epilepsy burden can be reduced mainly by giving epilepsy care at low cost, given the lack of expertise in the management of epilepsy in poor areas.

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