Comparative analysis of efficiency of some antiepileptic drugs monotherapy with the assessment of the dynamics of quality of life in patients with epilepsy

2021 ◽  
Vol 429 ◽  
pp. 119168
Author(s):  
Alimardon Ismatov ◽  
Kamola Mirzaeva
Keyword(s):  
Quality Of Life ◽  
Comparative Analysis ◽  
Antiepileptic Drugs ◽  
Patients With Epilepsy

Association of non-adherence to antiepileptic drugs and seizures, quality of life, and productivity: Survey of patients with epilepsy and physicians

2008 ◽  
Vol 13 (2) ◽  
pp. 316-322 ◽  
Author(s):  
Collin A. Hovinga ◽  
Miya R. Asato ◽  
Ranjani Manjunath ◽  
James W. Wheless ◽  
Stephanie J. Phelps ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiepileptic Drugs ◽  
Patients With Epilepsy

scholarly journals Psychosocial Problems and Physical Activity at Different Ages in Patients with Epilepsy

2018 ◽  
Vol 2 (89) ◽  
Author(s):  
Elvyra Grinienė ◽  
Viktorija Pečinina
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Antiepileptic Drugs ◽  
Physical Inactivity ◽  
Age Groups ◽  
Psychosocial Problems ◽  
Health Problems ◽  
Activity Levels ◽  
Patients With Epilepsy

Research background and hypothesis. Physical inactivity of patients with epilepsy is associated with the course of the disease, treatment, preconceived attitudes and myths that their physical activity might be dangerous and cause seizures (Steinhoff et al., 1996; Nakken, 2001 ).The aim of our research was to examine the links between the psychosocial problems of patients’ with epilepsy, their hysical activity, self-reported quality of life as well as their connection with patients’ age. Research  methods.  The  participants  were  209  patients  with  epilepsy  from  three  different  regions  (Šiauliai, Panevėžys and Pasvalys) of Lithuania. The subjects were selected with the help of quantitative closed-type survey – QOLIE-89 and IPAQ international questionnaire. The research findings were compared between two age groups: younger (20–39 years of age) and senior (40–59 years of age) subjects. Research results. The main psychosocial problems for patients with epilepsy were concerns about possible injuries during the seizures, experience of shame and other social restraint, health problems that might occur as a result of taking antiepileptic drugs for a long period of time, negative effects of antiepileptic drugs and memory impairments. These problems were more common among younger respondents (p < 0.05). Physical activity levels in patients with epilepsy were inadequate and different. The main factor that contributed to these differences was patients’ age. Younger respondents trained more in their leisure time, while seniors spent more time reading or sleeping (p = 0.002).Younger patients lacked knowledge about the most appropriate types of physical activities, senior  respondents  were  inactive  were  to  the  disapproval  of  medical  professionals  and  their  health  problems  (p = 0.006). Younger respondents evaluated their lifestyle as good enough more often than seniors. Discussion  and  conclusion.  Psychosocial  problems  and  physical  inactivity  of  patients  with  epilepsy  were connected with their age. Younger respondents more often than seniors were physically active and their self-reported quality of life was good.Keywords: age of patients with epilepsy, social problems, physical activity, evaluation of lifestyle.

A review on cost effective analysis of antiepileptic drugs

2017 ◽  
Vol 6 (9) ◽  
pp. 5507 ◽  
Author(s):  
Uthara S.S. ◽  
Mohammed Basheer ◽  
Anil Babu A.
Keyword(s):  
Quality Of Life ◽  
Developing Countries ◽  
Antiepileptic Drugs ◽  
Low Cost ◽  
Cost Effective ◽  
Global Burden ◽  
Patients With Epilepsy ◽  
Effective Analysis

80% of the epilepsy patients were resides in developing countries. 12 million patients with epilepsy were in India that is One-sixth of the global burden is due to epilepsy. Those diseases were treated properly there is a greater reduction in seizure and people may leads to proper life, if untreated that may become a large increase in burden. Drugs are the main treatment for epilepsy. As compared with conventional AEDs newer drugs are much expensive some newer drugs were 10 to 20 times costlier than older drugs. if those expensive drugs reduce the seizure events, improves the quality of life and with lesser ADRs then the benefit justify the higher cost of the drug. The epilepsy burden can be reduced mainly by giving epilepsy care at low cost, given the lack of expertise in the management of epilepsy in poor areas.

scholarly journals Effectiveness, safety and assessing the results of drug therapy in patients with epilepsy

2021 ◽  
Vol 13 (3) ◽  
pp. 306-310
Author(s):  
Article Editorial
Keyword(s):  
Quality Of Life ◽  
Drug Therapy ◽  
Antiepileptic Drugs ◽  
Psychiatric Comorbidity ◽  
Foreign Experience ◽  
History Of ◽  
Patients With Epilepsy

On June 26, 2021, a meeting of the experts of the Russian League Against Epilepsy (RLAE) was held, dedicated to the effectiveness, safety and assessing the results of drug therapy in patients with epilepsy. Having considered the history of the issue and guided by domestic and foreign experience, the participants discussed the problems associated with the use of various antiepileptic drugs for different forms of epilepsy in patients of different sex and age. Special attention was paid to psychiatric comorbidity in patients with epilepsy, increasing their compliance with treatment and quality of life. The article presents the Resolution of RLAE experts meeting adopted as a result of the discussion.

scholarly journals Antiepileptic drugs and quality of life in patients with epilepsy: A tertiary care hospital-based study

2019 ◽  
Vol 5 (2) ◽  
pp. 249-254
Author(s):  
Rizaldy Taslim Pinzon ◽  
Fransiscus Buwana ◽  
Rosa De Lima Renita Sanyasi ◽  
Andre Dharmawan Wijono ◽  
Jesisca .
Keyword(s):  
Quality Of Life ◽  
Antiepileptic Drugs ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Patients With Epilepsy

Features and methods of assessing health-related quality of life and cognitive functions in patients with glial tumors

2020 ◽  
pp. 47-56
Author(s):  
Vera Arsenyeva ◽  
Boris Martynov ◽  
Gennadiy Bulyshchenko ◽  
Dmitriy Svistov ◽  
Boris Gaydar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Functions ◽  
Well Being ◽  
Health Related Quality ◽  
Number Of Patients ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
Patients With Epilepsy

Gliomas make up about 8 cases per 100,000 population and the number of patients with this disease is only increasing. There can be not only various types of neurological deficits among the symptoms, but also personal and emotional changes, that seriously affects the quality of life. The modern model of health care includes not only recovery of the patient’s physical functions, but also his or her psychosocial well-being. In particular, the assessment and study of the characteristics of health-related quality of life, as well as cognitive functions in patients with gliomas, is increasingly recognized as an important criterion when considering the effectiveness of treatment. To date, the features of health related quality of life and cognitive functions of patients with epilepsy and acute cerebral circulation disorders have been studied sufficiently, and, as a result, techniques have been developed that accurately assess the QOL and CF in patients with these diseases. These are QOLIE-31 and QOLIE-AD-48 questionnaires for patients with epilepsy. This is the National Institutes of Health Stroke Scale (NIHSS), Orgogozo stroke scale (OSS), World Federation of Neurological Surgeons (WFNS) scale for the clinical assessment of subarachnoid hemorrhage (SAH) for patients with acute cerebrovascular accident. At the same time, there are no generally accepted methods for assessing quality of life and neurocognitive functions that are sensitive to changes in the condition of patients with gliomas in the early postoperative period by the time of discharge from the hospital. As a result, there is no systematic information on the dynamics of the quality of life of such patients, their neurocognitive functioning. The purpose of this article was to study the literature on QOL and CF in patients affected by neurological and neurosurgical disorders for the further selection of optimal methods for assessing dynamics of the condition of patients with glial brain tumors before and after surgery. At the moment, such requirements are only partially met by the EORTC QLQ-C30 questionnaire and its application EORTC QLQ-BN20.

Psychiatric and psychosocial morbidity 1 year after epilepsy surgery

2020 ◽  
pp. 1-8
Author(s):  
S. Patel ◽  
M. Clancy ◽  
H. Barry ◽  
N. Quigley ◽  
M. Clarke ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Epilepsy Surgery ◽  
Refractory Epilepsy ◽  
Post Surgery ◽  
Axis I ◽  
Patients With Epilepsy ◽  
The Impact

Abstract Objectives: There is a high rate of psychiatric comorbidity in patients with epilepsy. However, the impact of surgical treatment of refractory epilepsy on psychopathology remains under investigation. We aimed to examine the impact of epilepsy surgery on psychopathology and quality of life at 1-year post-surgery in a population of patients with epilepsy refractory to medication. Methods: This study initially assessed 48 patients with refractory epilepsy using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), the Hospital Anxiety and Depression Scale (HADS) and the Quality of Life in Epilepsy Inventory 89 (QOLIE-89) on admission to an Epilepsy Monitoring Unit (EMU) as part of their pre-surgical assessment. These patients were again assessed using the SCID-I, QOLIE-89 and HADS at 1-year follow-up post-surgery. Results: There was a significant reduction in psychopathology, particularly psychosis, following surgery at 1-year follow-up (p < 0.021). There were no new cases of de novo psychosis and surgery was also associated with a significant improvement in the quality of life scores (p < 0.001). Conclusions: This study demonstrates the impact of epilepsy surgery on psychopathology and quality of life in a patient population with refractory surgery. The presence of a psychiatric illness should not be a barrier to access surgical treatment.

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