Trends, Characteristics, and Success Rates of Treatment for Severe Early Childhood Caries Under General Anesthesia: A Retrospective Study in Northwest China

2021 ◽  
Vol 45 (4) ◽  
pp. 278-283
Author(s):  
Fei Liu ◽  
Keyu Yang ◽  
Panxi Wang ◽  
Tiantian Wu ◽  
Jinyi Li ◽  
...  
Keyword(s):  
Early Childhood ◽  
Retrospective Study ◽  
Early Childhood Caries ◽  
Composite Resin ◽  
Dental Treatment ◽  
Northwest China ◽  
Success Rates ◽  
Pulp Therapy ◽  
Severe Early Childhood Caries

Background/Objective: To retrospectively analyze the characteristics, tendencies, and success rates of dental treatments for severe early childhood caries (SECC) under general anesthesia (GA) in in northwest China. Study design: Children diagnosed with SECC were included in this retrospective study. From January 2015 to December 2018, they received dental treatment under GA at Affiliated Stomatology Hospital of Xi’an Jiaotong University. Demographic information, caries status and treatment characteristics were collected from electronic medical record system. Success rates of different treatments at 6-month and 12-month follow up were also analyzed. Results: A total of 846 children (477 male, 369 female) received dental treatment under GA. The case number was increased from 148 in 2015 to 278 in 2018. There were 81.2% and 70.8% of the children participated the 6-month and 12-month follow up. SSC and pulpotomy was the most successful restorations and pulp therapy, with the success rate of 97.09% and 93.98% in 12-month follow up, respectively. The use of crown restorations (including composite resin crown and stainless steel crown) and pulp reservation therapies (including indirect pulp therapy and pulpotomy) were significantly increased while composite resin filling and pulpectomy decreased during 2015 to 2018. Conclusion: There has been an increasing demand for dental treatment under GA for children with SECC in northwest China, with a trend toward younger ages. With better clinical outcomes, crown restorations and pulp reservation therapies were the fastest-growing treatments under GA.

Chemotherapy Induced Dental Changes in a Child with Medulloblastoma: A Case Report

2014 ◽  
Vol 38 (3) ◽  
pp. 251-254 ◽  
Author(s):  
B Peretz ◽  
H Sarnat ◽  
J Kharouba
Keyword(s):  
Early Childhood ◽  
Case Report ◽  
General Anesthesia ◽  
Early Childhood Caries ◽  
Dental Treatment ◽  
Gingival Tissue ◽  
Primary Molars ◽  
Dental Examination ◽  
Severe Early Childhood Caries

We describe the dental findings and therapeutic management of a child aged three years and eight months with medulloblastoma treated by surgical resection at age eight months followed by 20 months of chemotherapy. Thin and short roots of the primary molars were observed, as were microdontia and anodontia of the premolars. The boy suffered from severe early childhood caries (ECC). Dental treatment was carried out under general anesthesia. Follow-up examinations at three, six and twelve months after the initial dental treatment revealed healthy gingival tissue and no new caries. The boy passed away before the next scheduled follow-up dental examination.

Longitudinal Evaluation of Salivary Iga-S in Children with Early Childhood Caries Before and After Restorative Treatment

2019 ◽  
Vol 43 (4) ◽  
pp. 239-243 ◽  
Author(s):  
Aline dos Santos Letieri ◽  
Liana Bastos Freitas-Fernandes ◽  
Ana Paula Canedo Valente ◽  
Tatiana Kelly da Silva Fidalgo ◽  
Ivete Pomarico Ribeiro de Souza
Keyword(s):  
Early Childhood ◽  
Streptococcus Mutans ◽  
Flow Rate ◽  
Total Protein ◽  
Early Childhood Caries ◽  
Dental Treatment ◽  
Restorative Treatment ◽  
Lactobacillus Spp ◽  
Childhood Caries

Background: Our aim was to compare salivary levels of secretory immunoglobulin A (s-IgA) in children with early childhood caries (ECCG) and those who are caries-free (CFG) and verify these levels in a follow-up period after restorative treatment. Materials and methods: We selected 46 systemically healthy children in the complete primary dentition period, who were allocated into two groups: CFG (n = 23) and ECCG (dmf-s > 0; n = 23). Unstimulated whole saliva was obtained at baseline from both groups and during the follow-up period (7 days, 1, 2 and 3 months) in the ECCG group. The s-IgA was measured using an ELISA assay, and total protein was assessed using the Bradford method. We also evaluated the flow rate (mL/min), Streptococcus mutans and Lactobacillus spp. counting using selective media plaques. The data were submitted to statistical analysis using the software SPSS 20.0 (SPSS Inc, IL, USA) with a confidence interval set at 95%. Results: Salivary s-IgA levels were higher in baseline of ECCG than in CFG (p<0.05). No statistically significant differences were observed between s-IgA salivary levels at baseline and the evaluations after dental treatment in ECCG (p>0.05). However, we observed two different changes in s-IgA levels among participants: one group presented s-IgA reduction, and the other group demonstrated its maintenance. It was shown that patients from the ECCG group who presented a reduction in s-IgA levels during follow-up also showed a decrease in Streptococcus mutans and Lactobacillus spp. count (p<0.05), in contrast to patients who did not present this reduction. The flow rate and total protein were similar between groups (p>0.05). Conclusions: The present data support the idea that children with early childhood caries present higher levels of s-IgA in saliva than caries-free children. The restorative dental treatment does not have a significant influence on salivary levels of this immunoglobulin during the follow-up period.

scholarly journals Microbiota of Severe Early Childhood Caries before and after Therapy

2011 ◽  
Vol 90 (11) ◽  
pp. 1298-1305 ◽  
Author(s):  
A.C.R. Tanner ◽  
R.L. Kent ◽  
P. Lif Holgerson ◽  
C.V. Hughes ◽  
C.Y. Loo ◽  
...  
Keyword(s):  
Early Childhood ◽  
Early Childhood Caries ◽  
Lower Detection ◽  
Before And After ◽  
Dietary Component ◽  
Prevotella Species ◽  
Post Therapy ◽  
Severe Early Childhood Caries ◽  
Childhood Caries

Severe early childhood caries (ECC) is difficult to treat successfully. This study aimed to characterize the microbiota of severe ECC and evaluate whether baseline or follow-up microbiotas are associated with new lesions post-treatment. Plaque samples from 2- to 6-year-old children were analyzed by a 16S rRNA-based microarray and by PCR for selected taxa. Severe-ECC children were monitored for 12 months post-therapy. By microarray, species associated with severe-ECC (n = 53) compared with caries-free (n = 32) children included Slackia exigua (p = 0.002), Streptococcus parasanguinis (p = 0.013), and Prevotella species (p < 0.02). By PCR, severe-ECC-associated taxa included Bifidobacteriaceae (p < 0.001), Scardovia wiggsiae (p = 0.003), Streptococcus mutans with bifidobacteria (p < 0.001), and S. mutans with S. wiggsiae (p = 0.001). In follow-up, children without new lesions (n = 36) showed lower detection of taxa including S. mutans, changes not observed in children with follow-up lesions (n = 17). Partial least-squares modeling separated the children into caries-free and two severe-ECC groups with either a stronger bacterial or a stronger dietary component. We conclude that several species, including S. wiggsiae and S. exigua, are associated with the ecology of advanced caries, that successful treatment is accompanied by a change in the microbiota, and that severe ECC is diverse, with influences from selected bacteria or from diet.

Prosthetic Rehabilitation in a Four-year-old Child with Severe Early Childhood Caries: A Case Report

2009 ◽  
Vol 10 (2) ◽  
pp. 90-97 ◽  
Author(s):  
Thaís Manzano Parisotto ◽  
Cíntia Maria de Souza-e-Silva ◽  
Carolina Steiner-Oliveira ◽  
Marinês Nobre-dos-Santos ◽  
Maria Beatriz Duarte Gavião
Keyword(s):  
Stainless Steel ◽  
Early Childhood ◽  
Case Report ◽  
Early Childhood Caries ◽  
Dental Treatment ◽  
Prosthetic Rehabilitation ◽  
Oral Rehabilitation ◽  
Removable Prosthesis ◽  
Severe Early Childhood Caries ◽  
Childhood Caries

Abstract Aim The purpose of this case report was to describe the oral rehabilitation of a 4-year-old girl presenting early childhood caries (ECC). Background ECC is highly prevalent in developing countries and its severity increases with age. This disease implies serious consequences for the development of the stomatognathic system and for the child's quality of life. As young children are usually anxious about dental treatment, their level of co-operation is limited, leading to a challenging situation. Case Report A 4-year-old girl was brought by her mother for dental treatment with the complaint of pain. The clinical examination revealed extensive carious coronary destructions. After preventive and curative measures, the oral rehabilitation was performed; it included the use of stainless steel crowns, resin filled celluloid crowns with previous cementation of glass post pins when necessary, an amalgam restoration, orthodontic treatment, and a partial removable prosthesis. The child has been monitored in the Pediatric Dentistry Clinic at 4-monthly intervals. Summary The oral rehabilitation was able to reestablish the oral health in the primary arches mutilated by early childhood caries. This is important for the establishment of an adequate mixed and permanent dentition, for proper facial and maxillary growth, and to the child's psychological and social development. Clinical Significance The full management, including preventive, psychological, and curative measures of a young child with severe ECC was found successful after 8 months of follow up. This result can encourage the clinicians to seek a cost-effective technique such as stainless steel crowns, resin filled celluloid crowns, and partial removable prosthesis to reestablish the oral functions and improve the child's psycho-social development. Citation Parisotto TM, Souza-e-Silva CM, Steiner-Oliveira C, Nobre-dos-Santos M, Gavião MBD. Prosthetic Rehabilitation in a Four-year-old Child with Severe Early Childhood Caries: A Case Report. J Contemp Dent Pract 2009 March; (10)2:090-097.

Magnetic Bead-Based Salivary Peptidome Profiling Analysis for Severe Early Childhood Caries

2014 ◽  
Vol 49 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Yan Si ◽  
Shuang Ao ◽  
Weijian Wang ◽  
Feng Chen ◽  
Shuguo Zheng
Keyword(s):  
Mass Spectrometry ◽  
Early Childhood ◽  
Early Childhood Caries ◽  
Expression Profiles ◽  
Salivary Protein ◽  
Preschool Age ◽  
Diagnostic Model ◽  
Peptide Mass ◽  
Severe Early Childhood Caries ◽  
Childhood Caries

Objective: To investigate the differential salivary protein expression profiles between children with severe early childhood caries (S-ECC) and caries-free (CF) children at the age of 3 years. Methods: We used matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) combined with weak cation exchange magnetic beads, and peptide mass fingerprints were created by scanning mass spectrometry signals. Salivary samples from 20 children were analyzed (10 for each group). Results: Eleven protein peaks were significantly different (p < 0.05) between the two groups. Eight of these peaks were higher in the S-ECC group and three were higher in the CF group. To establish a diagnostic model for discrimination between the two groups, we chose three peptides (3,186.2, 3,195.8 and 3,324.8 Da) that exhibited the best fitted curve, by which the two groups were better separated when compared with other combinations. Conclusions: The salivary biomarkers identified revealed significant differences between the CF and the S-ECC group. Our results provide novel insight into the salivary protein profile of preschool-age children with dental caries and may lead to the development of a new strategy for screening high-risk populations.

scholarly journals Dental Treatments under the General Anesthesia in a Child with Keratitis, Ichthyosis, and Deafness Syndrome

2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Sera Sımsek Derelioglu ◽  
Yücel Yılmaz ◽  
Sultan Keles
Keyword(s):  
Early Childhood ◽  
Case Report ◽  
General Anesthesia ◽  
Early Childhood Caries ◽  
Sensorineural Deafness ◽  
Oral Symptoms ◽  
Severe Early Childhood Caries ◽  
Childhood Caries

KID syndrome is a rare genodermatosis characterized by keratitis, ichthyosis, and sensorineural deafness. Although the dermatological, ophthalmologic, and sensorineural defects are emphasized in the literature, oral and dental evaluations are so superficial. In this case report, dental and oral symptoms of a three year and five months old boy with KID syndrome, suffering severe Early Childhood Caries (s-ECC) and dental treatments done under General Anesthesia (GA) were reported.

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