Effectiveness of treatment with carbamide peroxide and hydrogen peroxide in subjects affected by dental fluorosis: a clinical trial

2004 ◽  
Vol 28 (1) ◽  
pp. 63-67 ◽  
Author(s):  
Juan Pablo Loyola-Rodriguez ◽  
Amaury de Jesus Pozos-Guillen ◽  
Felipe Hernandez-Hernandez ◽  
Rocio Berumen-Maldonado ◽  
Nuria Patiño-Marin

Dental fluorosis is an endemic dental health problem around the world; so, it is important to develop clinical alternatives that are non-invasive and inexpensive. In this study, nightguard vital bleaching technique (NVBT), using carbamide and hydrogen peroxide as active agents, has shown itself to be effective in whitening teeth affected by dental fluorosis. Carbamide peroxide at 10 and 20% and hydrogen peroxide at 7.5% showed good clinical effectiveness in improving clinical appearence, but it is important to point out that clinical success is only in cases of class 1 to 3 of the Tooth Surface Index of Fluorosis. When comparing 10 and 20% concentrations of carbamide peroxide, there was no difference in the clinical effectiveness (p>0.05); but when comparing both concentrations of carbamide peroxide against hydrogen peroxide, results showed that carbamide peroxide was more effective in whitening in cases of dental fluorosis, the difference being statistically significant (p<0.05). NVBT has two advantages: it is a non-invasive technique and the relationship cost/benefit is excellent; only a few patients reported tenderness or mild tooth sensitivity.

2018 ◽  
Vol 91 (2) ◽  
pp. 229-233 ◽  
Author(s):  
Sanket Hans Pandey ◽  
Pallav Mahesh Patni ◽  
Pradeep Jain ◽  
Arpita Chaturvedi

Introduction. Non-vital bleaching is a non-invasive technique to treat the intrinsic discoloration of teeth of several etiologies. Hydrogen peroxide and sodium perborate are commonly used bleaching agents.Aim. The aim of this case report is to demonstrate the non-vital bleaching technique in maxillary anterior teeth.Method. Maxillary central incisors were isolated with rubber dam and root canal treatment was performed. Barrier space preparation was done using a heated instrument. Glass ionomer cement was used a barrier material. Mixture of hydrogen peroxide and sodium perborate was placed in the canal and sealed with intermediate restorative material. After 1 week, the procedure was repeated to achieve the desired results.Conclusion. Non-vital bleaching is a minimally invasive procedure to restore the esthetics of a discolored non-vital tooth. However, care should be taken to prevent any post-operative complications.


2019 ◽  
Vol 8 (9) ◽  
pp. 1387 ◽  
Author(s):  
Marta Delsoglio ◽  
Najate Achamrah ◽  
Mette M. Berger ◽  
Claude Pichard

Indirect calorimetry (IC) is considered as the gold standard to determine energy expenditure, by measuring pulmonary gas exchanges. It is a non-invasive technique that allows clinicians to personalize the prescription of nutrition support to the metabolic needs and promote a better clinical outcome. Recent technical developments allow accurate and easy IC measurements in spontaneously breathing patients as well as in those on mechanical ventilation. The implementation of IC in clinical routine should be promoted in order to optimize the cost–benefit balance of nutrition therapy. This review aims at summarizing the latest innovations of IC as well as the clinical indications, benefits, and limitations.


2021 ◽  
Vol 6 (3) ◽  
pp. 181-184
Author(s):  
Manish Sundesha

Non-vital bleaching is a non-invasive technique for the treatment of intrinsic discoloration of teeth. Hydrogen peroxide and sodium perborate are commonly used bleaching agents. The aim of this case report is to demonstrate the non-vital bleaching technique in maxillary anterior teeth. Maxillary central incisors were isolated and root canal treatment was performed. Barrier space preparation was done using a heated instrument. Glass ionomer cement was used a barrier material. Mixture of hydrogen peroxide was placed in the canal and sealed with intermediate restorative material. After 1 week, the procedure was repeated to achieve the desired results. Non-vital bleaching is a minimally invasive procedure to restore the esthetics of a discoloured non-vital tooth. However, care should be taken to prevent any post-operative complications.


Zygote ◽  
2000 ◽  
Vol 8 (1) ◽  
pp. 15-24 ◽  
Author(s):  
James R. Trimarchi ◽  
Lin Liu ◽  
D. Marshal Porterfield ◽  
Peter J.S. Smith ◽  
David L. Keefe

The physiology of the early embryo may be indicative of embryo vitality and therefore methods for non-invasively monitoring physiological parameters from embryos could improve preimplantation diagnoses. The self-referencing electrophysiological technique is capable of non-invasive measurement of the physiology of individual cells by monitoring the movement of ions and molecules between the cell and the surrounding media. Here we use this technique to monitor gradients of calcium, potassium, oxygen and hydrogen peroxide around individual mouse preimplantation embryos. The calcium-sensitive electrode in self-referencing mode identified a region of elevated calcium concentration (∼0.25 pmol) surrounding each embryo. The calcium gradient surrounding embryos was relatively steep, such that the region of elevated calcium extended into the medium only 4 μm from the embryo. By contrast, using an oxygen-sensitive electrode an extensive gradient of reduced dissolved oxygen concentration was measured surrounding the embryo and extended tens of micrometres into the medium. A gradient of neither potassium nor hydrogen peroxide was observed around unperturbed embryos. We also demonstrate that monitoring the physiology of embryos using the self-referencing technique does not compromise their subsequent development. Blastocysts studied with the self-referencing technique implanted and developed to term at the same frequency as did unexamined, control embryos. Therefore, the self-referencing electrode provides a valuable non-invasive technique for studying the physiology and pathophysiology of individual embryos without hindering their subsequent development.


2020 ◽  
Vol 48 (10) ◽  
pp. 030006052096753
Author(s):  
Qingqing Wang ◽  
Qingfei Meng ◽  
Jian Meng

Dental fluorosis is a dental condition caused by excessive intake of fluoride during enamel formation, which can lead to color abnormalities or defects on the tooth surface. The resultant abnormal appearance ranges in severity from mildly white and opaque to dark brown, which substantially affects patients’ esthetic characteristics and self-confidence. Treatment methods include tooth whitening or restoration. This clinical report describes the use of a minimally invasive esthetic technique in a 22-year-old woman with moderate dental fluorosis. The treatment plan included enamel microabrasion, at-home bleaching for 2 weeks, and subsequent resin infiltration for each tooth under a rubber dam. After 2 years of follow-up, evaluation of the patient’s esthetic appearance revealed that teeth affected by dental fluorosis could be successfully treated with a minimally invasive technique involving microabrasion, at-home bleaching, and resin infiltration.


2009 ◽  
Vol 79 (1) ◽  
pp. 122-126 ◽  
Author(s):  
Virna Cavalcante Patusco ◽  
Gil Montenegro ◽  
Marcos Augusto Lenza ◽  
Adilson Alves de Carvalho

Abstract Objective: To test the hypothesis that there is no difference between the action of at-home and in-office vital bleaching on the shear bond strength of metallic brackets bonded with composite resin 24 hours after bleaching. Materials and Methods: Forty-five human upper premolars were randomly divided into three groups: (1) control, (2) 10% carbamide peroxide at-home bleached, and (3) 35% hydrogen peroxide in-office bleached. Twenty-four hours after bleaching the teeth were pumiced, bonded with metallic brackets, and stored in distilled water. One day after bonding the shear bond strength of the brackets was determined. Results: The mean shear bond strength of Group 1 (control) and Group 2 (carbamide peroxide bleached) were not statistically different. Group 3 (hydrogen peroxide bleached) had a significantly lower mean shear bond strength than Group 1 and Group 2. Conclusions: The hypothesis is rejected. Use of 10% carbamide peroxide bleaching does not significantly alter shear bond strength values. On the other hand, use of 35% hydrogen peroxide bleaching significantly reduces these values and diminishes the amount of resin remnant on the tooth surface after bracket debonding.


2014 ◽  
pp. 9-18
Author(s):  
Thi Linh Giang Truong ◽  
Vu Quoc Huy Nguyen

Background: Assessment of fetal health plays the most important role in prenatal care because of influence of the prediction of gestational outcome. One of the main aims of routine antenatal care is to identify the ‘ at risk ‘ fetus in order to apply clinical interventions which could results in reduced perinatal morbidity and mortality. Doppler ultrasound is a non invasive technique whereby the movement of blood is studied by detecting the change in frequence of reflected sound, Doppler blood flow velocity waves form of fetal side (umbilical artery, middle cerebral artery ...) and maternal side ( uterine arteries) are discussed and monograms for routine practice are presented. Recently this method is important tool for qualifying high risk pregnancies and help early forecasts the health of the babies and mothers disorder. Doppler sonography in obstetrics is a widely accepted functional method of examining the prediction of gestational outcome. Key words: Doppler, umbilical artery, middle cerebral artery, uterine arteries


2019 ◽  
Vol 15 (2) ◽  
pp. 138-144
Author(s):  
Fabiana Vieira Lima ◽  
Aline Farias ◽  
Cassiana Mendes ◽  
Simone Gonçalves Cardoso ◽  
Marcos Antônio Segatto Silva

Background: The carbamide peroxide is the most commonly active ingredient used for home dental whitening products, its quantification in pharmaceutical products is of extreme importance due to the relation with the products potency and the previously related low carbamide peroxide stability. Once, there is only one official carbamide peroxide determination based on iodometric titration, this method is time-consuming and generates a lot of residues. The aim of this study was to carry out development and validation of a simple and fast ultraviolet spectrophotometer assay to quantify an innovative dental whitening gel. Methods: The proposed method was validated according international conference on harmonization guideline. Procedure is based on the iodide/iodine redox chemistry; iodine released through the action of hydrogen peroxide of carbamide peroxide with ultraviolet detection at 350 nm. Results: The procedure was linear in the concentration range of 1.0-4.0 µg/mL, specific to the excipients, robust for the evaluated parameters (variation of wavelength (± 5 nm); reagent addition (± 10%)), showing the results of RSD 1.88 and 0.39% respectively. Repeatability precision was RSD = 1.42%, with accurate RSD = 2.15% by adding reference solution. The assay used only water as solvent for sample preparation. In comparison to the pharmacopeial method, the latter is more time-consuming, as it generates a lot of residues, and it could not quantify small CP dosages. Conclusion: Thus, the proposed method was proved to be suitable to determine carbamide peroxide during the development and characterization of nanoparticle formulations in the present study.


2021 ◽  
Vol 6 (1) ◽  
pp. e000766
Author(s):  
Ismail Mayet ◽  
Shelley-Ann McGee ◽  
Naseer Ally ◽  
Hassan Dawood Alli ◽  
Mohammed Tikly ◽  
...  

ObjectiveTo compare the cost implications of botulinum neurotoxin (BNT) injection to surgery in infantile esotropia (IE) in a public/government funded hospital.Methods and analysisA simple costing comparison was undertaken for a randomised clinical trial in IE. Patients were randomised to receive either BNT or standard surgery. The participants in the BNT arm were further subdivided into subgroups based on their age in months and degree of esotropia in prism dioptres (PD) at presentation: G1 ≤60 PD/24 months, G2 ≤24 months/>60 PD, G3 >24 months/≤60 PD, G4 >24 months/>60 PD. The costs were calculated for each arm from primary treatment to eventual satisfactory outcome defined as orthophoria or microtropia (≤10 PD). A bottom-up costing analysis was done for single and multiple procedures for each arm. Comprehensive variable costs as well as fixed costs were calculated at each point of intervention and expressed in local currency ZAR (US$1=ZAR15.00). Costing was analysed for surgery and BNT subgroups (based on clinical success)ResultsThere were 101 patients enrolled in the trial. 54 in the BNT arm and 47 in the surgery arm. Cost for single surgery and single BNT was ZAR 7743.04 and 1713.14, respectively. A favourable clinical outcome was achieved in 72% of surgery arm and 37% of BNT arm. The mean cost for eventual favourable outcome in BNT arm was ZAR9158.08 and in surgery arm ZAR9124.27 (p=0.26). Mean cost in G1 was ZAR6328.45, in G2 ZAR7197.45, in G3 ZAR11891.93 and G4 ZAR12882.44 (p=0.018).ConclusionBNT has a cost–benefit in IE and is a viable option in the primary treatment of IE in resource constrained regions. Clinical outcomes and economic benefit in smaller angle of esotropia and younger patients are comparable to surgery.


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