An efficient synthesis of bis-indolyloxindoles from (phenylimino)indolin-2-ones and 1H-indole catalyzed by Citric acid

2015 ◽  
Vol 2 (8) ◽  
pp. 365-370
Keyword(s):  
Citric Acid ◽  
Efficient Synthesis

Solvent-free and efficient synthesis of bicyclic 2-pyridone derivatives for endoplasmic reticulum imaging

2021 ◽  
Author(s):  
Xiaoyun Ran ◽  
Qian Zhou ◽  
Jin Zhang ◽  
Shanqiang Wang ◽  
Gui Wang ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Citric Acid ◽  
Core Structure ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
The Core ◽  
Catalyst Free ◽  
Synthesis Approach ◽  
Ethylenediamine Derivatives

Started from citric acid (CA) and ethylenediamine derivatives, a solvent-free, catalyst-free and highly yield synthesis approach for bicyclic 2-pyridones was presented. Continuing to modify the core structure, a series of...

ChemInform Abstract: Green Approach for the Efficient Synthesis of Quinolines Promoted by Citric Acid.

ChemInform ◽  
2009 ◽  
Vol 40 (7) ◽  
Author(s):  
Ramu Enugala ◽  
Sreelatha Nuvvula ◽  
Vijay Kotra ◽  
Ravi Varala ◽  
Srinivas R. Adapa
Keyword(s):  
Citric Acid ◽  
Efficient Synthesis ◽  
Green Approach

One-pot, Green and Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones or Thiones Catalyzed by Citric Acid

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Arash Ghorbani-Choghamarani ◽  
Tahereh Taghipour ◽  
Gouhar Azadi
Keyword(s):  
Citric Acid ◽  
Efficient Synthesis ◽  
One Pot

Green Approach for the Efficient Synthesis of Quinolines Promoted by Citric Acid

Heterocycles ◽  
2008 ◽  
Vol 75 (10) ◽  
pp. 2523 ◽  
Author(s):  
Srinivas R. Adapa ◽  
Ramu Enugala ◽  
Sreelatha Nuvvula ◽  
Vijay Kotra ◽  
Ravi Varala ◽  
...  
Keyword(s):  
Citric Acid ◽  
Efficient Synthesis ◽  
Green Approach

An efficient synthesis of 2-hydroxy-gibberellins

1986 ◽  
Vol 29 (9) ◽  
pp. 1109-1112
Author(s):  
M Beale
Keyword(s):  
Efficient Synthesis

A new facile and efficient synthesis of trans-(+)-sobrerol by biotransformation of α-pinene using extremophiles microorganisms

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
LA Vilaseca ◽  
J Quillaguamán ◽  
L Fuentes ◽  
O Sterner
Keyword(s):  
Efficient Synthesis

Coadministration of citric acid allows oxytetracycline dose reduction in yellowtail Seriola quinqueradiata infected with Vibrio anguillarum

2020 ◽  
Vol 140 ◽  
pp. 25-29
Author(s):  
K Akiyama ◽  
N Hirazawa ◽  
A Hatanaka
Keyword(s):  
Body Weight ◽  
Citric Acid ◽  
Effective Treatment ◽  
Dose Reduction ◽  
Vibrio Anguillarum ◽  
Enhancing Effect ◽  
Bacterial Diseases ◽  
Seriola Quinqueradiata ◽  
Poor Efficacy

Oxytetracycline (OTC) has been commonly used as an effective antibiotic against various fish bacterial diseases, including vibriosis. In this study, the absorption-enhancing effect of citric acid on oral OTC pharmacokinetics and treatment of artificial Vibrio anguillarum infection was evaluated in juvenile yellowtail Seriola quinqueradiata followed by serum OTC concentration analysis. When 25 mg kg-1 body weight (BW) OTC was administered in combination with 1250 mg kg-1 BW citric acid, the serum OTC concentration reached almost the same concentration as that of the group treated with 50 mg kg-1 BW OTC. This coadministration successfully suppressed mortality due to vibriosis similar to the group treated with 50 mg kg-1 BW OTC. Conversely, poor efficacy was observed when only 25 mg kg-1 BW OTC was administered. These results suggest that coadministration of citric acid can be beneficial in reducing the dose of OTC needed for effective treatment, and thus contributes to the goal of reduced use of this antibiotic in aquaculture.

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