A clinical case of the novel coronavirus (COVID-19) reinfection in a health care worker

2021 ◽  
Vol 27 (2) ◽  
pp. 195-200
Author(s):  
Irina V. Kovtyukh ◽  
Gennady E. Gendlin ◽  
Igor G. Nikitin ◽  
Ekaterina V. Kabirova ◽  
Olga Yu. Markina

The peculiarities of immune responses to a novel coronavirus infection (COVID-19) and the possibility of reinfection due to the variability of humoral immunity are currently under discussion. This article presents a case of COVID-19 reinfection in a health care worker.

2021 ◽  
Vol 9_2021 ◽  
pp. 232-236
Author(s):  
Shklyaev A.E. Shklyaev A ◽  
Bessonov A.G. Bessonov A ◽  
Chushyalova D.A. Chushyalova D ◽  
Mikhailova M.D. Mikhailova M ◽  
Meleshkina M.V. Meleshkina M ◽  
...  

2020 ◽  
Vol 4 (4) ◽  
pp. 214-218
Author(s):  
R.F. Khamitov ◽  

Acute respiratory infections of the upper and lower respiratory tract are currently the leading cause of human morbidity, mainly due to the seasonal rise of the incidence rates of viral infections. This results in the heavy burden of annual health care costs. The COVID-19 pandemic exacerbated the problem. The associations between respiratory viruses and bacteria are not always clear thus accounting for the diversity of the risks of the complicated course and fatal outcomes of various bacterial viral coinfections. Influenza virus is associated with the high rate of bacterial complications (in particular, during seasonal peaks). Meanwhile, this is less typical of the novel coronavirus infection. In addition, several studies demonstrate the competitive edge of SARS-CoV-2 when interacting with other respiratory viruses. The specificities of viral bacterial associations greatly affect the treatment whose inadequacy (in particular, the prescription of antibiotics) is the leading cause of the increasing antimicrobial resistance of contemporary germs. The novel coronavirus infection SARS-CoV-2 is no exception in terms of inappropriate antibiotic prescribing as occurred often in the seasonal rise of acute respiratory viral infections. The understanding of this issue, the optimization of treatment strategies, and a reduction in health care costs will allow for preserving antibiotics as a class of highly effective medications. KEYWORDS: acute respiratory infections, COVID-19, bacterial coinfection, outpatient care, lung damage, antimicrobial therapy. FOR CITATION: Khamitov R.F. Acute respiratory infections in outpatient care in the era of the COVID-19 pandemic: the role and position of antibacterial therapy. Russian Medical Inquiry. 2020;4(4):214–218. DOI: 10.32364/2587-6821-2020-4-4-214-218.


2021 ◽  
Vol 17 (2) ◽  
pp. 4-15
Author(s):  
E. P. Pavlikova ◽  
M. A. Agapov ◽  
P. S. Malakhov ◽  
E. A. Galliamov ◽  
Yu. S. Esakov ◽  
...  

During the care of patients with novel coronavirus infection at the Lomonosov MSU Medical Research and Education Center from April 21 to June 13, 2020, we observed cases of spontaneous mediastinal emphysema (spontaneous pneumomediastinum) as a manifestation or a probable complication of COVID-19.The aim of the paper. To provide clinical case descriptions and approaches to the management of patients with spontaneous pneumomediastinum in COVID-19 associated pneumonia, as they are not addressed in the current clinical guidelines, and therefore are worthy of special attention.Among 224 patients with laboratory-confirmed diagnosis of the novel coronavirus infection COVID-19, five cases of pneumomediastinum without pneumothorax were identified. Of these, in two cases the pneumomediastinum developed during noninvasive lung ventilation (NLV) (one case) and invasive lung ventilation (one case). In three cases, spontaneous mediastinal emphysema was not associated with lung ventilation. By the time of publication, one case of pneumomediastinum was completed, and four patients remained hospitalized. All five patients were males aged from 52 to 84 years.This paper presents in depth the description of two cases of mediastinal and subcutaneous emphysema in patients with COVID-19.


2021 ◽  
pp. 22-26
Author(s):  
S. V. Orlova ◽  
E. A. Nikitina ◽  
E. V. Prokopenko ◽  
L. Yu. Volkova ◽  
A. N. Vodolazkaya

Thousands of studies have been conducted to study the new SARS-CoV-2 coronavirus, its infectious properties, transmission routes and all associated with the clinical manifestations and severity of COVID-19, especially with potential treatments. Lactoferrin is a member of the transferrin family, which is synthesized by epithelial cells of mammalian internal glands and is widely present in various secretory fluids such as milk, saliva, tears, and nasal secretions. Lactoferrin is one of the components of the innate humoral immunity, regulates the functions of immunocompetent cells and is a acute phase protein. Lactoferrin has strong antioxidant and anti-inflammatory properties. This review assesses the possibility of using lactoferrin as a supplement in immunocorrective therapy programs for viral diseases, including the novel coronavirus infection COVID-19.


2021 ◽  
Vol 93 (5) ◽  
Author(s):  
Daria G. Rumiantceva ◽  
Margarita M. Urumova ◽  
Shandor F. Erdes

The novel coronavirus infection COVID-19 (SARS-CoV-2) is now known to cause a variety of extrapulmonary complications, including cardiovascular, neurological and dermatological complications, many of which occur or last several weeks after infection. We present a clinical case of a patient who first developed symptoms of ankylosing spondylitis 2 weeks after recovering from COVID-19. The patient was prescribed therapy in accordance with international and Russian recommendations for the management of patients with ankylosing spondylitis with a positive effect in the form of absence arthritis, enthesitis and reducing the inflammatory back pain.


2020 ◽  
Vol 34 (1-2) ◽  
pp. 24-27
Author(s):  
Aakash Pandita ◽  
Girish Gupta

The world has recently been hit by a pandemic caused by the novel Coronavirus infection. The infection is highly contagious and possesses a significant risk for health care workers caring for the infected patients. With more than 200 countries being affected and around 3,00,000 deaths across the globe, the essential supply of masks and personal protective equipment has been falling short of the ever increasing need. In such crisis there is a need for innovating and designing endogenous masks and equipment to avoid compromise in care of the effected patients and for safeguarding the health of health care workers.


2021 ◽  
Vol 162 (17) ◽  
pp. 643-651
Author(s):  
Zoltán Szekanecz ◽  
Krisztina Bogos ◽  
Tamás Constantin ◽  
Béla Fülesdi ◽  
Veronika Müller ◽  
...  

Összefoglaló. Az új típusú koronavírus-fertőzés (COVID–19) nagy terhet ró az egészségügyi ellátórendszerre és a társadalomra. A betegségnek három nagy szakasza van, melyek alapvetően meghatározzák a kezelést. Az I–IIA fázisban az antivirális, míg a IIB–III. fázisban a gyulladásgátló kezelés áll előtérben, melyhez intenzív terápiás, szupportív kezelés csatlakozik. A jelen ajánlás kizárólag a gyógyszeres kezelésre vonatkozik, és a rendelkezésre álló bizonyítékok alapján foglalja össze a terápiás lehetőségeket. Emellett egy javasolt kezelési algoritmust is tartalmaz. Orv Hetil. 2021; 162(17): 643–651. Summary. The novel coronavirus infection (COVID-19) places a heavy burden on the health care system and our society. There are three major stages in the disease that fundamentally determine treatment approaches. Phases I–IIA require primarily antiviral treatment. In phases IIB–III, anti-inflammatory treatment is needed accompanied by intensive and supportive care. This recommendation applies only to pharmacotherapy and summarizes the therapeutic options based on the available evidence. It also includes a proposed treatment algorithm. Orv Hetil. 2021; 162(17): 643–651.


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