scholarly journals The use of computer techniques to optimize the diagnosis of tuberculosis in HIV-infected patients at the secondary diseases stage

Author(s):  
Karina T. Umbetova ◽  
Daria D. Arutyunova ◽  
Andrey N. Gerasimov ◽  
Olga F. Belaya ◽  
Valerii A. Malov ◽  
...  

Вackground: The course of tuberculosis in HIV-infected patients has no significant clinical and diagnostic differences from damage to organs and systems of other etiology. The growth of new cases of HIV / TB co-infection necessitates a revision of diagnostic approaches, their improvement in order to increase the efficiency of examination and management of HIV-infected patients, depending on the stage and indicators of the immune status. The aim of the study was to determine by the method of complex statistical processing the main clinical and laboratory-instrumental criteria for improving the diagnosis of tuberculosis in HIV-infected patients at the stage of secondary diseases. Methods: The study design was retrospective. The object of the research was the case histories of 113 patients with HIV infection at the stage of secondary diseases (classification by V.I. Methods of parametric and nonparametric statistics, computer analysis of images with the gradient program proposed by Dr. Sci. A.N. Gerasimov, to assess the possibility of using micro- and macro-preparations of tissues and organs of patients with HIV infection. Results: Using the method of correlation adaptometry, it was found that there are no significant differences in the clinical course of HIV-infected patients with tuberculosis of various localization, and with lesions of the respiratory organs of other etiology. The use of multivariate probability models made it possible to identify significant diagnostic risk factors for lethal outcome - 66.7% of patients with further lethal outcome complained of chest pain during breathing (p = 0.004), and ESR was significantly accelerated in patients with a lethal outcome in the hospital 77 1.99 (p = 0.019). Conclusion: The multicomplex instrumental and laboratory examination makes it possible to diagnose tuberculosis of various localization at the initial stage of development. The use of computer techniques optimizes and unifies the diagnostic search in patients with HIV infection and determines the timely treatment tactics

2018 ◽  
Vol 10 (3) ◽  
pp. 61-69 ◽  
Author(s):  
D. D. Arutyunova ◽  
K. T. Umbetova ◽  
Yu. G. Parchomenko ◽  
O. A. Tishkevich ◽  
E. V. Volchkova ◽  
...  

The development of mesenteric lymphadenitis is typical for patients with HIV infection at the stage of secondary diseases. The purpose of our study is to decipher the etiology of lymphadenitis in patients with HIV infection at the stage of secondary diseases. The analysis of disease histories of 113 HIV infection patients at the stage of secondary diseases with the use of statistical processing was carried out. The article presents examples that characterize the polymorphism of clinical variants of the development of mesadenitis in HIVinfected patients with stage 4B, which has developed as a result of the influence of various etiological factors.


Author(s):  
D. D. Arutyunova ◽  
A. N. Gerasimov ◽  
Karina T. Umbetova ◽  
N. V. Maloletneva ◽  
O. F. Belaya ◽  
...  

At the stage of secondary HIV disease, the tuberculosis process often loses its specificity, which makes it difficult to diagnose timely, first of all, tuberculosis and leads to late appointment of etiotropic therapy. The purpose of our study was to study the characteristics of tuberculosis infection course in patients with HIV at the stage of secondary diseases using correlation adaptometry. The analysis of disease histories of 113 HIV infection patients at the stage of secondary diseases with the use of statistical processing was carried out. Using correlation adaptometry, it was established that HIV-infected patients do not have significant differences in the course and clinical manifestations of pulmonary and extrapulmonary forms of tuberculosis.


2021 ◽  
pp. 34-41
Author(s):  
Mohamed Hamada ◽  
Daniya Temirkhanova ◽  
Diana Serikbay ◽  
Sanzhar Salybekov ◽  
Saltanat Omarbek

The main objective of the research is identifying the effectiveness of artificial intelligence in the business sphere of Kazakhstan. The urgency of this problem is due to the fact that the Kazakhstani market for artificial intelligence is at the initial stage of development. The main obstacle to the introduction of artificial intelligence is the unpreparedness of managers of small and medium-sized businesses for the application of artificial intelligence technologies and, of course, the high cost of their implementation. In the study, we proceeded from the key thesis that business in Kazakhstan is striving for digital transformation. We set a goal to determine the attitude and degree of readiness of Kazakhstani business to the implementation and practical application of artificial intelligence, to describe the cases of using artificial intelligence by Kazakhstani business, to identify the main questions that arise in business at this stage, to study the legal aspects of using artificial intelligence in business and to present the big picture compliance / inconsistency of the existing legal framework with the goals and objectives of the development of artificial intelligence, provide recommendations for eliminatinge xisting barriers and stimulating businesses to implement the technology. Within the framework of this study, the concept of artificial intelligence is defined in its broadest sense - as a set of technologies for processing various types of data and information, in particular those capable of interpreting such data, extracting knowledge and using it to achieve certain goals.


2008 ◽  
Vol 7 (2) ◽  
pp. 444-450 ◽  
Author(s):  
M.L. Camparoto ◽  
B. Fulan ◽  
C.M. Colli ◽  
M.L. Paludo ◽  
A.L. Falavigna-Guilherme ◽  
...  

2009 ◽  
Vol 45 (2) ◽  
pp. 189-200 ◽  
Author(s):  
Carolina Fracalossi Rediguieri

The study shows how nanotechnology evolves in developed countries and Brazil, raising aspects of private and governmental initiatives. The investigation was based in scientific literature, electronic articles and conference reports. Several sources of literature were used, including electronic databases and reference lists. By this study, it was observed that, although nanotechnology is in initial stage of development all over the world, the developed countries have had growing public and private investments in the area each year. In those countries, there is a concern toward both, the formation of specialists in nanotechnology and the transference of technology developed in universities and research institutes to industry. In Brazil, the study showed that despite the growing concern of investigators, national research centers and financial centers toward the development of the nanotechnology, there is still a need for more investment and formation of area specialists.


1970 ◽  
Vol 6 (3) ◽  
pp. 320-326 ◽  
Author(s):  
L. V. Al'tshuler ◽  
A. V. Balabanov ◽  
V. A. Batalov ◽  
V. A. Rodionov ◽  
D. M. Tarasov

Author(s):  
Yunusov Kh.B

This concept creates favorable conditions for the development and implementation of mechanisms for the development of school science education in Samarkand region of the Republic of Uzbekistan taking into account the programs developed and implemented at the current stage of development of the region. This approach allows us to strengthen the position with staffing for teachers (biology, chemistry, physics, mathematics) of the secondary school and to achieve the integration of rural and city schools to create a single educational space. It will increase the motivation of students and activate the work of teachers of biology, chemistry, physics, and mathematics, which will lead to the full formation of the initial stage of professional orientation in the natural sciences


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