scholarly journals Molecular mechanisms of cyclic transformation of the endometrium

2019 ◽  
Vol 68 (1) ◽  
pp. 5-12
Author(s):  
Gulrukhsor Kh. Tolibova ◽  
Tatyana G. Tral ◽  
Eduard K. Ailamazyan ◽  
Igor Yu. Kogan
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Structural Transformation ◽  
Molecular Mechanisms ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
Biological Interactions ◽  
Genetically Determined

Structural transformation of the endometrium during the menstrual cycle is a genetically determined process and is provided by complex molecular-biological interactions aimed at the onset and development of pregnancy. Sex steroid hormones play a key role in endometrial morphogenesis, which mediate or directly affect angiogenesis and immunogenesis.

Fundamental Frequency Variations Across the Menstrual Cycle and the Use of an Oral Contraceptive Pill

2020 ◽  
Vol 63 (4) ◽  
pp. 1033-1043
Author(s):  
Filipa M. B. Lã ◽  
Nuria Polo
Keyword(s):  
Oral Contraceptive ◽  
Standard Deviation ◽  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Fundamental Frequency ◽  
Oral Contraceptive Pill ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
Contraceptive Pill ◽  
The Voice

Purpose Concentrations of sex steroid hormones—estrogens, progesterone, and testosterone—have been associated with premenstrual and menstrual vocal symptoms. However, the extent to which these symptoms may be reflected on acoustical features of the voice is still debated. This study investigates variations in fundamental frequency ( f o ) and related parameters in connected speech across phases of the menstrual cycle and during the use of a combined oral contraceptive pill (OCP). Method Electrolaryngographic recordings were made, and blood samples were collected at three different phases of the menstrual cycle—menstrual, follicular, and luteal—for placebo and OCP use. These two conditions were blindly and randomly allocated in the study. Speaking f o (SFF), SFF standard deviation, SFF rate of change, SFF slope, maximum and minimum f o , and f o range were extracted for nine healthy females while reading a phrase from the Rainbow Passage. Concentrations of sex hormones were analyzed in serum. Nonparametric statistical tests were carried out to assess differences between phases and conditions. Results SFF, its standard deviation, and maximum f o were significantly different between phases of the menstrual cycle for placebo use only. Menstrual phase showed the lowest values. Maximum and minimum f o were significantly different between placebo and OCP use for menstrual and follicular phases, respectively. Conclusions Fluctuations in sex steroid hormones across the menstrual cycle alter f o in speech more than a particular hormonal concentration. OCP use seems to have a stabilizing effect on the voice relative to f o and related parameters in speech.

scholarly journals A study on influence of different phases of menstrual cycle on hematological parameters

2021 ◽  
Vol 38 (3) ◽  
pp. 308-311
Author(s):  
Vijayashri Basavaraj HANCHINAL ◽  
Ambhuja SAMBRANI ◽  
Vineet BALJOSHI
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Hematological Parameters ◽  
Endocrine System ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
Monocyte Count ◽  
Significant Difference ◽  
The Impact ◽  
Fertile Women

Menstruation is the most common phenomenon observed in fertile women. Menstrual cycle (MC) is of 3 phases: proliferative phase, secretory phase and menstruation phase. It is controlled by endocrine system. Natural fluctuations in sex steroid hormones during MC causes changes in hematological parameters. The aim of the present study to assess the impact of different phases of MC on hematological parameters. The study was conducted in KIMS, Hubli, from 01st March 2011 to 31st March 2012. Women aged between 20-30 years with regular menstrual cycle of 27-30 days were included in the study. During each visit, the subjects’ blood was collected and analyzed using KX-21 SYSMEX for various hematological parameters. A total of 50 healthy young women were included in the study. On statistical comparing of hematological parameters, hematocrit, hemoglobin, neutrophil count and eosinophil count showed a significant difference while no statistically significant difference was observed in RBC, leucocyte count, lymphocyte count, monocyte count, erythrocyte sedimentation rate (ESR) and platelet count between different phases of MC. To conclude, the hematological parameters during the MC are highly dependent on the phasic changes in the immune response mechanism and sex steroid hormones.

Influence of the Menstrual Cycle Phase on Marathon Performance in Recreational Runners

2020 ◽  
pp. 1-4
Author(s):  
M. Greenhall ◽  
R.S. Taipale ◽  
J.K. Ihalainen ◽  
A.C. Hackney
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Luteal Phase ◽  
Female Athletes ◽  
Complete Information ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
Cycle Phase ◽  
Marathon Running ◽  
Marathon Performance

Purpose: To examine the potential impact of fluctuations in sex steroid hormones across the menstrual cycle (MC) on marathon running performance of recreational female athletes. Methods: A survey questionnaire was administered to recreational, nonelite runners who had completed multiple marathons within the last 18 months. Results: A total of 599 questionnaires were returned and deemed viable for review. From these, 185 survey participants were found to have complete information and eligibility to have their surveys used in the statistical analysis. A total of 106 women had their best marathon performance in the luteal phase (high sex steroid hormones) of the MC, and 79 had their best performance in the follicular phase (low sex steroid hormones) of the MC (responses were significantly different; z-score value = 1.11; P < .05). Conclusion: Recreational female runners have varying performances in the marathon across their MC phases, specifically performing better in the luteal phase of the cycle.

Atherosclerosis and sex hormones: current concepts

2010 ◽  
Vol 119 (12) ◽  
pp. 493-513 ◽  
Author(s):  
Amparo C. Villablanca ◽  
Muthuvel Jayachandran ◽  
Carole Banka
Keyword(s):  
Hormone Therapy ◽  
Steroid Hormones ◽  
Sex Hormones ◽  
Vessel Wall ◽  
Molecular Mechanisms ◽  
Disease Risk ◽  
Sex Steroid Hormones ◽  
Metabolic Effects ◽  
Sex Steroid

CVD (cardiovascular disease) is the leading cause of death for women. Considerable progress has been made in both our understanding of the complexities governing menopausal hormone therapy and our understanding of the cellular and molecular mechanisms underlying hormone and hormone receptor function. Understanding the interplay of atherosclerosis and sex steroid hormones and their cognate receptors at the level of the vessel wall has important ramifications for clinical practice. In the present review, we discuss the epidemiology of CVD in men and women, the clinical impact of sex hormones on CVD, and summarize our current understanding of the pathogenesis of atherosclerosis with a focus on gender differences in CVD, its clinical presentation and course, and pathobiology. The critical animal and human data that pertain to the role of oestrogens, androgens and progestins on the vessel wall is also reviewed, with particular attention to the actions of sex hormones on each of the three key cell types involved in atherogenesis: the endothelium, smooth muscle cells and macrophages. Where relevant, the systemic (metabolic) effects of sex hormones that influence atherogenesis, such as those involving vascular reactivity, inflammation and lipoprotein metabolism, are discussed. In addition, four key current concepts in the field are explored: (i) total hormone exposure time and coronary heart disease risk; (ii) the importance of tissue specificity of sex steroid hormones, critical timing and the stage of atherosclerosis in hormone action; (iii) biomarkers for atherosclerosis with regard to hormone therapy; and (iv) the complex role of sex steroids in inflammation. Future studies in this field will contribute to guiding clinical treatment recommendations for women and help define research priorities.

scholarly journals Influence of sex-steroid hormones on the regulation of lymphocyte beta 2-adrenoceptors during the menstrual cycle.

1994 ◽  
Vol 37 (6) ◽  
pp. 583-588 ◽  
Author(s):  
NM Wheeldon ◽  
DM Newnham ◽  
WJ Coutie ◽  
JA Peters ◽  
DG McDevitt ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
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