On the dietetic treatment of gastric ulcers and hyperacidic catarrhs

1927 ◽  
Vol 23 (10) ◽  
pp. 1003-1009
Author(s):  
N. E. Kavetsky ◽  
K. S. Promakhin
Keyword(s):  
Gastric Secretion ◽  
Gastric Juice ◽  
Dietary Treatment ◽  
Gastric Ulcers ◽  
Duodenal Ulcers ◽  
Complete Cure ◽  
Dietetic Treatment

Dietary treatment of gastric and duodenal ulcers is currently given great importance, and quite a number of methods have been proposed for this purpose (Lehnboe, Lenhartz, Senator, Rosenfeld, Petren, Riegel, Steesma, Vasiliev, Schnabel, Zweig, Boas, Yarotsky, Sippy and others). Having no possibility to stop here on all these ways, we will touch only the diet proposed by Prof. A. I. Yarotsky. This diet, based on works of I.P. Pavlov school, is directed to change the very character of gastric secretion. Its task is not only to eliminate subjective sufferings of the patient, but also to lead him to complete cure and decrease of acidity of gastric juice (prof. Yarotsky attaches particular importance to the latter).

Cimetidine Utilization in Denmark 1977–1981

1986 ◽  
Vol 14 (1) ◽  
pp. 7-14 ◽  
Author(s):  
K. Schmidt ◽  
J. Mosbech ◽  
E. Worsøe
Keyword(s):  
Geographical Variation ◽  
Application Rate ◽  
Hospital Utilization ◽  
Gastric Ulcers ◽  
Age Group ◽  
Utilization Pattern ◽  
Duodenal Ulcers ◽  
National Board ◽  
Ulcer Disease ◽  
Proxy Variables

A description of development in the utilization pattern of cimetidine (Tagamet) in Denmark is given on the basis of 19 154 granted applications for individual drug reimbursement submitted to the National Board of Health from the initial registration of cimetidine in September 1977 until general reimbursement was introduced in July 1981. The application rate per 100000 inhabitants increased steeply from 49 in 1978 to 148 in 1980 and decreased to 127 in 1981. Despite this rapid introduction, however, hospital utilization for ulcer disease was constant during this period. Half of the applications treated diagnosed duodenal ulcers and a third gastric ulcers. Only 50% of those gastric ulcers were diagnosed by endoscopy. The age-specific application rate reached a peak in the age group of 50–69 years. There was a considerable geographical variation in the rate of application. The reason for this is unknown, since the variations in the ages of patients and years of application were different in different counties, and no correlation between application rate and proxy variables for standard of health and special interest in ulcer disease between the different counties could be shown.

scholarly journals Incidence of Duodenal Ulcers and Gastric Ulcers in a Western Population: Back to Where It Started

2009 ◽  
Vol 23 (9) ◽  
pp. 604-608 ◽  
Author(s):  
Marcel JM Groenen ◽  
Ernst J Kuipers ◽  
Bettina E Hansen ◽  
Rob J Th Ouwendijk
Keyword(s):  
Gastric Ulcers ◽  
Bleeding Complications ◽  
Upper Gastrointestinal Endoscopy ◽  
Peptic Ulcers ◽  
Duodenal Ulcers ◽  
Ulcer Disease ◽  
Treatment Regimens ◽  
H Pylori ◽  
Upper Gastrointestinal ◽  
Over Time

BACKGROUND/OBJECTIVES: As recently as 40 years ago, a decline in the incidence of peptic ulcers was observed. The discovery of Helicobacter pylori had a further major impact on the incidence of ulcer disease. Our aim was to evaluate the trends in the incidence and bleeding complications of ulcer disease in the Netherlands.METHODS: From a computerized endoscopy database of a district hospital, the data of all patients who underwent upper gastrointestinal endoscopy from 1996 to 2005 were analyzed. The incidence of duodenal and gastric ulcers, with and without complications, were compared over time.RESULTS: Overall, 20,006 upper gastrointestinal endoscopies were performed. Duodenal ulcers were diagnosed in 696 (3.5%) cases, with signs of bleeding in 158 (22.7%). Forty-five (6.5%) of these ulcers were classified as Forrest I and 113 (16.2%) as Forrest II. Gastric ulcers were diagnosed in 487 cases (2.4%), with signs of bleeding in 60 (12.3%). A Forrest 1 designation was diagnosed in 19 patients (3.9%) and Forrest 2 in 41 patients (8.4%). The incidence of gastric ulcers was stable over time, while the incidence of duodenal ulcers declined.CONCLUSIONS: The incidence of duodenal ulcer disease in the Dutch population is steadily decreasing over time. Test and treatment regimens for H pylori have possibly contributed to this decline. With a further decline in the prevalence of H pylori, the incidence of gastric ulcers is likely to exceed the incidence of duodenal ulcers in the very near future, revisiting a similar situation that was present at the beginning of the previous century.

scholarly journals Prevalence of Helicobacter pylori infection among patients undergoing upper gastrointestinal endoscopy

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Vudumula Vijaya Lakshmi
Keyword(s):  
Duodenal Ulcer ◽  
Helicobacter Pylori ◽  
Normal Population ◽  
Gastric Ulcers ◽  
Upper Gastrointestinal Endoscopy ◽  
Contributing Factors ◽  
Duodenal Ulcers ◽  
Female Ratio ◽  
Ulcer Disease ◽  
H Pylori

Helicobacter pylori (H. pylori) has a role in the multifactorial etiology of peptic ulcer disease. A link between H. pylori infection and duodenal ulcer disease is now established. Other contributing factors and their interaction with the organism may initiate the ulcerative process. The fact that eradication of H. pylori infection leads to a long-term cure in the majority of duodenal ulcer patients and the fact that the prevalence of infection is higher in ulcer patients than in the normal population are cogent arguments in favor of it being the primary cause of the ulceration. This study was under taken at the Department of surgery, Narayana medical college, Nellore from January 2007 to July 2008. A total of 150 patients with duodenal ulcers, gastric ulcers, antral gastritis, gastric carcinoma and dyspepsia of any kind were studied. Maximum number of cases were in the age group of 31 years to 50 years among both sexes and number of cases gradually decreased after 50 years of age in males and females. Males were more in number and male to female ratio is (2.75:1) approximately 3:1.

scholarly journals Therapeutic Potency of Gallium verum Extract on Ethanol-Induced Gastric Ulcer in Rats

2021 ◽  
Vol 12 (5) ◽  
pp. 6010-6020
Keyword(s):  
Gastric Juice ◽  
Gastric Ulcers ◽  
Ethanol Administration ◽  
Gastric Injury ◽  
Glutathione S Transferase ◽  
Histological Lesion ◽  
Immunohistochemical Markers ◽  
Ulcer Group ◽  
Tnf Α ◽  
Promising Treatment

Gallium verum, lady's bedstraw is an herbaceous annual plant belonging to the genus Rubiaceae; it possessed antioxidant, cytotoxic for cancer cells, antimicrobial, protective and endocrine effects. This work aimed to investigate the curative effects of G. verum extract on gastric ulcers following absolute ethanol administration in the healthy rat. Eighteen rats were randomly divided into three main groups; rats were fastened for 24 hours before ethanol administration. All groups except control administered ethanol (5 ml/kg body weight; orally). The rats were administrated distilled water (Ulcer group) or G. verum extract (100mg/kg) one hour later. G. verum extract caused a significant decrease in ulcer index, gastric juice volume, malondialdehyde, and nitric oxide, while gastric juice pH, glutathione, glutathione-S-transferase, and catalase increased significantly. The histological lesion score showed a significant enhancement in group G. verum compared to the ulcer group that scored the highest pathological destruction score. Immunohistochemical markers of NF-κB p65 and TNF-α showed a significant decrease in G. verum group. G. verum extract is a promising treatment modality against gastric injury through its powerful antioxidant, acid neutralizing, healing promotion, and ant-inflammation effects.

On the pathology of gastric secretion of the peasant population

1930 ◽  
Vol 26 (12) ◽  
pp. 1190-1194
Author(s):  
V. E. Rodionov
Keyword(s):  
Gastric Secretion ◽  
Gastric Juice ◽  
Motor Function ◽  
Laboratory Data ◽  
The State ◽  
Objective Data ◽  
Gastric Diseases ◽  
Gastric Glands ◽  
Chemical Studies ◽  
Physiological Structure

As you know, the majority of gastric suffering is based on the pathology of the secretory and motor function of the stomach, depending or without it on the organic changes in its anatomical and physiological structure. In the presence of a complex of anamnestic and objective data, the state of secretion in each given case is laid on the basis for the diagnosis of gastric diseases, why the laboratory data in connection with the clinic serve as the starting material in our article. We took the result of chemical studies of gastric juice carried out in the Ardatov laboratory for 10 years from 1919 to 1928 inclusive in the amount of 2277 cases. We believe that this material is sufficient to reveal some aspects of the pathology of the function of the gastric glands depending on the conditions of nutrition and life of the peasant population, especially since in relation to nutrition during this period of time the population was in very different conditions.

Radiotherapy for gastric ulcers in the light of radiobiology and clinical data

1934 ◽  
Vol 30 (2) ◽  
pp. 310-316
Author(s):  
R. Ya. Gasul
Keyword(s):  
Gastric Juice ◽  
Clinical Data ◽  
Gastric Ulcers ◽  
Malignant Neoplasms ◽  
X Rays

In spite of the fact that already in 1913 the first quite successful attempts were made to treat gastric ulcers with X-rays (Kodo) and to influence the secretion and acidity of gastric juice with the help of illumination (Brgel, 1916), the clinic has not yet shown sufficient interest in the use of X-rays in the treatment of ulcers and their complications. Some clinicians still believe that only malignant neoplasms are treated with X-rays, and only those that are rejected by surgeons.

Inhibition of gastric secretion by thyroid preparations

1959 ◽  
Vol 196 (6) ◽  
pp. 1262-1265 ◽  
Author(s):  
E. S. Nasset ◽  
V. W. Logan ◽  
M. L. Kelley ◽  
Mary Thomas
Keyword(s):  
Gastric Secretion ◽  
Gastric Juice ◽  
Gradual Decline ◽  
Heidenhain Pouch ◽  
Significant Fall ◽  
Lean Beef ◽  
Inhibition Of Gastric Secretion

Four dogs with Thomas gastric pouches and one dog with a Heidenhain pouch were stimulated to secrete gastric juice by feeding 100 gm of lean beef. Feeding whole desiccated thyroid ordinarily caused a significant fall in volume of gastric juice and in the total quantity of HCl secreted. Crystalline thyroxine yielded erratic results and one trial with triiodothyronine produced a significant increase in gastric secretion. Thyroidectomy in one dog resulted in a gradual decline in secretion, but hypothyroidism produced by administration of mercaptoimidazole in another animal lead to a significant increase in secretion.

Chronic gastroduodenal ulcers in patients with diabetes mellitus

2003 ◽  
Vol 49 (1) ◽  
pp. 5-10
Author(s):  
Yu. L. Fedorchenko
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Clinical Course ◽  
Gastrin Level ◽  
Gastric Ulcers ◽  
Peptic Ulcers ◽  
Duodenal Ulcers ◽  
Patients With Diabetes ◽  
H Pylori

The clinical picture, course, and treatment of gastroduodenal ul­cers (GDU) in diabetics were studied. A total of 395 diabetics were examined; GDU were detected in 36. The incidence of gas­tric and duodenal ulcers was similar in patients with insulin-de­pendent diabetes mellitus, while in patients with non-insulin-de- pendent diabetes gastric ulcers predominated. The clinical pic­ture of the disease, gastric acid production, Helicobacter pylori infection, and blood gastrin levels were studied in all patients with ulcers. The efficiency of GDU treatment with quamatel, raniti­dine, and antacids was evaluated. The clinical course of GDU in diabetics was asymptomatic. The highest incidence of H. pylori, infection was observed in patients with type 1 diabetes with con­comitant peptic ulcers. Serum gastrin levels were more frequently increased in patients with type 1 diabetes and duodenal ulcers and normal in patients with type 2 diabetes. Quamatel therapy was highly effective in diabetics with GDU. Ulcers healed in 85% patients and blood gastrin level significantly decreased after 3- week therapy. GDU in diabetics are characterized by specific lo­cation, clinical course, laboratory and instrumental features, which allows a differentiated approach to therapy of these pa­tients.

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