scholarly journals Comparison between the efficacy plant and synthetic origin dental products in the treatment of chronic catarrhal gingivitis.

2020 ◽  
Vol 101 (1) ◽  
pp. 25-30
Author(s):  
Y S Lyamin ◽  
Yu S Fedorova ◽  
P V Kulpin ◽  
N I Suslov ◽  
D V Kucheryavyi
Keyword(s):  
Quality Of Life ◽  
Comparison Group ◽  
Main Group ◽  
Subjective Quality ◽  
Control Group ◽  
Chlorhexidine Digluconate ◽  
Subjective Quality Of Life ◽  
Complex Therapy ◽  
Complex Drug

Aim. Comparative clinical study of hygienic dental product of plant origin based -mangostin [1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one], a xanthone from mangosteen fruit, having antimicrobial and anti-inflammatory activity in the treatment of chronic generalized catarrhal gingivitis. Methods. The study included 319 patients aged 22 to 45 years. All patients were divided into two groups: the control group 20 people (males 40%, females 60%), average age 34.88.00 years; the comparison group 20 people (males 45%, females 55%), average age 35.07.10 year; the main group 20 people (males 40%, females 60%), average age 34.97.86 years. There were no statistically significant differences between all groups (p 0.05). The nosological form of the disease in the studied patients is chronic generalized catarrhal gingivitis (K05.1). Treatment in all groups was carried out using the standard regimen of complex therapy of chronic generalized catarrhal gingivitis. Therapy of the main group patients was supplemented by the use of the hygienic gel containing 1% -mangostin [1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one], whereas treatment of the comparison group patients was supplemented by the complex preparation containing 1% metronidazole and 0.25% chlorhexidine digluconate. The dental examination included a questionnaire with the registration of subjective data (patient complaints) and objective data on the state of the tissues of the mouth (index score) before and after therapy, as well as the dynamics of the indicators fixing during the entire treatment. Results. The performing a comparative study of the treatment effectiveness of chronic generalized catarrhal gingivitis, using a dental hygienic gel containing 1% -mangostin [1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one] as a part of complex therapy in comparison with the standard complex treatment regimen supplemented by dental product containing 1% metronidazole and 0.25% chlorhexidine digluconate, showed a marked improvement in subjective quality of life of patients. Pain during individual oral hygiene and food intake (decrease to 0%, p1 0.05, p2 0.05), a feeling of bursting in the gum (decrease to 0%, p1 0.05, p2 0.05), bad breath (decrease to 0%, p1 0.05, p2 0.05) and bleeding gums (decrease to 0%, p1 0.05, p2 0.05) were completely eliminated. Compared to the control group, OHI-S index of the main group decreased by 79% (from 1.9 to 0.4, p1 0.001, p2 0.001), PI index decreased by 80.6% (from 3.1 to 0.6, p1 0.001, p2 0.001) and SBI index decreased by 100% (from 3 to 0, p1 0.001, p2 0.001). During the course of treatment of patients with chronic generalized catarrhal gingivitis, a decrease in the average values of the PMA index was observed. In the group of patients using hygienic gel as a supplement to treatment, the decrease in this index was 85% (from 651.53 to 100.82%; p1 0.001, p2 0.05), and when using a complex drug containing 1% metronidazole and 0.25% chlorhexidine digluconate, the value of the PMA index decreased by 51% (from 611.17 to 301.4%; p1 0.001), in the control group, the index value decreased by 28% (from 671.67 to 481.26%; p1 0.001). Conclusion. In assessing of the subjective quality of life and index indicators of the periodontal status in the treatment of chronic generalized catarrhal gingivitis, the best results were observed in the group using a dental hygiene gel based on -mangostin [1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one], a xanthone from mangosteen fruit, compared with the control group and the group using a complex drug (1% metronidazole and 0.25% chlorhexidine digluconate).

scholarly journals Peculiarities of Quality of Life in Patients with Pemphigus Vulgaris according to the Results of the Analysis of the SF-36V2 Questionnaires and Dermatological Index of Quality of Life in the Background of Glucocorticosteroid Therapy

2021 ◽  
Vol 6 (6) ◽  
pp. 123-133
Author(s):  
V. A. Litvinov ◽  
Keyword(s):  
Quality Of Life ◽  
Comparison Group ◽  
Negative Impact ◽  
Pemphigus Vulgaris ◽  
Clinical Problem ◽  
Subjective Health ◽  
Main Group ◽  
Control Group ◽  
Index Of Quality

The purpose of the study was to carry out a comparative assessment of the parameters of the quality of life in patients with pemphigus vulgaris according to the results of the analysis of the SF-36V2 questionnaires and the dermatological index of the quality of life against the background of glucocorticosteroid therapy. Materials and methods. The results of the study are based on the data of a comprehensive study and further follow-up of 47 patients with pemphigus vulgaris (of which 30 are the main group and 17 are the comparison group) who were hospitalized at the Zaporizhzhya Regional Skin and Venereal Clinical Dispensary, Zaporizhzhia. At the time of observation, the majority of patients were aged 61-70 years old. As a control group, 20 apparently healthy people were examined, randomized by age and sex. Results and discussion. Pemphigus vulgaris is a severe systemic dermatosis, which, according to the literature, accounts for about 1% in the structure of dermatological pathology, the main pathomorphological sign of which is acantholysis. Although the share of pemphigus vulgaris in the structure of dermatological pathology is 0.6 per 100 thousand people per year, the severity of the disease and its outcome determine the relevance of further study of the pathogenesis of dermatosis and the search for new effective therapies. The etiology of true pemphigus still remains unclear. The obtained results of questioning the patients with the SF-36V2 questionnaires and the dermatological index of quality of life indicate a significant negative impact of pemphigus vulgaris on the key parameters of the quality of life of patients in the main group and in the comparison group before treatment – the ability to perform their daily duties, work or study, have personal relationships, and also on the desire to be treated and adhere to all the rules of the therapy. Patients with pemphigus vulgaris in the group of monotherapy with glucocorticosteroids had statistically worse indicators of the quality of life after treatment than patients with additional use of Armadin, which was characterized by a low level of physical activity, an increase in the role of physical and psychoemotional problems in everyday life, general discomfort and subjective health. Conclusion. Evaluation of the quality of life of patients allowed for a more qualified study of the health disorders of patients with pemphigus vulgaris, to see the essence of the clinical problem, to select the most optimal treatment regimen for each patient, and also to assess the expected results in terms of parameters that are on the verge of a scientific approach and evidence-based medicine on the one hand, and also the subjective point of view of patients with pemphigus vulgaris on the other hand

Cognitive determinants of community functioning and quality of life in homeless adults with mental illness: 6-year follow-up from the At Home/Chez Soi Study Toronto site

2021 ◽  
pp. 1-9
Author(s):  
K. M. Gicas ◽  
C. Mejia-Lancheros ◽  
R. Nisenbaum ◽  
R. Wang ◽  
S. W. Hwang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Functional Outcomes ◽  
Verbal Learning ◽  
Subjective Quality ◽  
Subjective Quality Of Life ◽  
Homeless Adults ◽  
Community Functioning ◽  
At Home

Abstract Background High rates of physical and mental health comorbidities are associated with functional impairment among persons who are homeless. Cognitive dysfunction is common, but how it contributes to various functional outcomes in this population has not been well investigated. This study examines how cognition covaries with community functioning and subjective quality of life over a 6-year period while accounting for the effects of risk and protective factors. Methods Participants were 349 homeless adults (mean age = 39.8) recruited from the Toronto site of the At Home/Chez Soi study, a large Canadian randomized control trial of Housing First. Participants completed up to four clinical evaluations over 6 years. Factor scores were created to index verbal learning and memory (vLM) and processing speed-cognitive flexibility (PSCF). The primary outcomes were community functioning and subjective quality of life. Risk factors included lifetime homelessness, mental health diagnoses, medical comorbidity, and childhood adversity. Linear mixed-effects models were conducted to examine cognition-functional outcome associations over time, with resilience as a moderator. Results Better vLM (b = 0.787, p = 0.010) and PSCF (b = 1.66, p < 0.001) were associated with better community functioning, but not with quality of life. Resilience conferred a protective effect on subjective quality of life (b = 1.45, p = 0.011) but did not moderate outcomes. Conclusions Our findings suggest a need to consider the unique determinants of community functioning and quality of life among homeless adults. Cognition should be prioritized as a key intervention target within existing service delivery models to optimize long-term functional outcomes.

Existential/spiritual resources and the subjective quality of life experiences among elderly adults

2015 ◽  
Vol 13 (4) ◽  
pp. 123-168 ◽  
Author(s):  
Magdalena Kapała
Keyword(s):  
Quality Of Life ◽  
The Elderly ◽  
Subjective Quality ◽  
Modern World ◽  
Life Questionnaire ◽  
Elderly Adults ◽  
Subjective Quality Of Life ◽  
Spiritual Resources ◽  
Two Phases

AbstractMy paper presents the results of a research study on the relationship between existential/spiritual resources, that is, spiritual sensitivity (a disposition to experience spirituality, manifested in the embracement of the nature of things in the transcendent and final perspective, in moral sensitivity, and the ability to find meaning in paradoxical and limiting situations), spiritual sensitivity components and subjective quality of life (a generalized attitude to one’s own life mode, in the four existential dimensions: psychophysical, psycho-social, subjective, and metaphysical). Study subjects were older adults (60+, n = 522) living in the current, dynamic, uncertain and fluid modern world conditions. The study had two phases – quantitative and qualitative (narrative interviews). To measure the phenomena, the Spiritual Sensitivity Inventory (Straś-Romanowska, Kowal, & Kapała, 2013) and the Quality of Life Questionnaire (Straś-Romanowska, Oleszkowicz, & Frąckowiak, 2004) were used. The results obtained confirmed a strong mutual relationship between spiritual resources and quality of life, also providing an answer to some questions about the nature of spiritual sensitivity, and its integrating, pro-development and pro-health role in the elderly adults’ life in the post-modern era.

THE SIGNIFICANCE OF OBJECTIVE DETERMINANTS FOR THE SUBJECTIVE QUALITY OF LIFE

1998 ◽  
Vol 60 (1) ◽  
pp. 113-114 ◽  
Author(s):  
Peter Herschbach ◽  
Gerhard Henrich
Keyword(s):  
Quality Of Life ◽  
Subjective Quality ◽  
Subjective Quality Of Life

Determinants of subjective quality of life in post acute patients with schizophrenia

2003 ◽  
Vol 253 (5) ◽  
pp. 228-235 ◽  
Author(s):  
Andreas Bechdolf ◽  
Joachim Klosterkötter ◽  
Martin Hambrecht ◽  
Bärbel Knost ◽  
Christina Kuntermann ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Subjective Quality ◽  
Subjective Quality Of Life ◽  
Acute Patients
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