scholarly journals The effectiveness of volume guarantee ventilation in newborns

2021 ◽  
Vol 10 (2) ◽  
pp. 165-172
Author(s):  
Il’dar M. Ziganshin ◽  
Ajnagul’ Zh. Bayalieva ◽  
Anna A. Babintseva ◽  
Gul’nar R. Shaimardanova

Background. An important goal of treating respiratory disorders in newborns during the first stage of perinatal care is effective and safe pulmonary ventilation, enabling the administration of surfactant therapy, reducing alveolar dead space, and providing adequate gas exchange. Objective. The aim of this study is to improve the quality of newborns respiratory therapy using double pressure and volume control at the first stage of perinatal care. Materials and methods. The study involved newborns from week 27 to week 42 gestation with respiratory failure requiring invasive pulmonary ventilation. The ventilation mode was evaluated with pressure control and volume guarantee option compared with routine pressure ventilation. For the comparative characteristic of the compared ventilation methods, we used targets, such as the duration of artificial pulmonary ventilation, reduction of FiO2, dynamics of venous blood lactate, peak and average pressure in the respiratory tract, dynamics of lung compliance, and the development of complications. Results and conclusions. Given the heterogeneity of lung damage in newborns, the use of the guaranteed volume option reduced the duration of mechanical ventilation, the development frequency of IVH, and the frequency of surfactant use.

2003 ◽  
Vol 48 (2) ◽  
pp. 46-48 ◽  
Author(s):  
D St J O Reilly ◽  
R Carter ◽  
E Bell ◽  
J Hinnie ◽  
P J°Galloway

The cardio-pulmonary and biochemical changes observed in a case of McArdle's disease, exercising with increasing work rates to exhaustion in °the “second-wind” phase of exercise are reported for the first time. A °work rate of 2 75–325 °watts was achieved. Venous blood lactate remained unchanged throughout. The plasma ammonium level reached a plateau of approximately 400 °mmol/l at 100 °watts. At a work rate of 150–175 watts the ratio of O2 consumption to CO2 production increased, the inverse of an anaerobic threshold. Maximal cardio-pulmonary responses were achieved at 200 watts. During the final periods of exercise from 200 to 275/325 °watts pulmonary ventilation did not significantly change but there was a decrease in the venous blood H+ concentration, and pO2 and in increase in the pCO2 Creatine supplementation at 25 °g/day for five days did not improve exercise performance.


1993 ◽  
Vol 75 (6) ◽  
pp. 2727-2733 ◽  
Author(s):  
K. H. McKeever ◽  
K. W. Hinchcliff ◽  
D. F. Gerken ◽  
R. A. Sams

Four mature horses were used to test the effects of two doses (50 and 200 mg) of intravenously administered cocaine on hemodynamics and selected indexes of performance [maximal heart rate (HRmax), treadmill velocity at HRmax, treadmill velocity needed to produce a blood lactate concentration of 4 mmol/l, maximal mixed venous blood lactate concentration, maximal treadmill work intensity, and test duration] measured during an incremental treadmill test. Both doses of cocaine increased HRmax approximately 7% (P < 0.05). Mean arterial pressure was 30 mmHg greater (P < 0.05) during the 4- to 7-m/s steps of the exercise test in the 200-mg trial. Neither dose of cocaine had an effect on the responses to exertion of right atrial pressure, right ventricular pressure, or maximal change in right ventricular pressure over time. Maximal mixed venous blood lactate concentration increased 41% (P < 0.05) with the 50-mg dose and 75% (P < 0.05) with the 200-mg dose during exercise. Administration of cocaine resulted in decreases (P < 0.05) in the treadmill velocity needed to produce a blood lactate concentration of 4 mmol/l from 6.9 +/- 0.5 and 6.8 +/- 0.9 m/s during the control trials to 4.4 +/- 0.1 m/s during the 200-mg cocaine trial. Cocaine did not alter maximal treadmill work intensity (P > 0.05); however, time to exhaustion increased by approximately 92 s (15%; P < 0.05) during the 200-mg trial.(ABSTRACT TRUNCATED AT 250 WORDS)


Resuscitation ◽  
2012 ◽  
Vol 83 ◽  
pp. e27-e28
Author(s):  
Charlotte Barfod ◽  
Lars Hyldborg Lundstrøm ◽  
Marlene Mauson Pankoke Lauritzen ◽  
Jakob Klim Danker ◽  
György Sölétormos ◽  
...  

2017 ◽  
Vol 15 (1) ◽  
pp. 22-26 ◽  
Author(s):  
Leandro C. Felippe ◽  
Guilherme A. Ferreira ◽  
Fernando De-Oliveira ◽  
Flavio O. Pires ◽  
Adriano E. Lima-Silva

2021 ◽  
Author(s):  
Congli Zeng ◽  
David Lagier ◽  
Jae-Woo Lee ◽  
Marcos F. Vidal Melo

Pulmonary atelectasis is common in the perioperative period. Physiologically, it is produced when collapsing forces derived from positive pleural pressure and surface tension overcome expanding forces from alveolar pressure and parenchymal tethering. Atelectasis impairs blood oxygenation and reduces lung compliance. It is increasingly recognized that it can also induce local tissue biologic responses, such as inflammation, local immune dysfunction, and damage of the alveolar–capillary barrier, with potential loss of lung fluid clearance, increased lung protein permeability, and susceptibility to infection, factors that can initiate or exaggerate lung injury. Mechanical ventilation of a heterogeneously aerated lung (e.g., in the presence of atelectatic lung tissue) involves biomechanical processes that may precipitate further lung damage: concentration of mechanical forces, propagation of gas–liquid interfaces, and remote overdistension. Knowledge of such pathophysiologic mechanisms of atelectasis and their consequences in the healthy and diseased lung should guide optimal clinical management.


1988 ◽  
Vol 69 (5) ◽  
pp. 677-682 ◽  
Author(s):  
Honorio T. Benzon ◽  
J. Richard Toleikis ◽  
Laura L. Meagher ◽  
Barry A. Shapiro ◽  
Chung-hsin Ts'ao ◽  
...  

2012 ◽  
Vol 203 ◽  
pp. 18-21
Author(s):  
Hui Fang ◽  
Wei Tang ◽  
Yan Jing Meng

The paper analyzes the method of direct tension control, provides repaired method of closed loop speed for tension control of underfeed winder, and designs the systematic hardware figuration and software to effectively meet the demands of different volume control. Furthermore, the problems including pressure control of pressing roller, load distribution control of two-drum winder, tension control of paper, and dynamic compensation control were analyzed and solved through the design of hardware and software of S7-300 PLC.


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