scholarly journals Comparative evaluation of the results of conservative and surgical methods of treatment of children with destructive forms of pyelonephritis

2021 ◽  
Vol 11 (3) ◽  
pp. 339-350
Author(s):  
Galina I. Kuzovleva ◽  
Elena V. Grushitskaya ◽  
Oleg V. Staroverov ◽  
Vera V. Rostovskaya ◽  
Oleg S. Shmyrov ◽  
...  

BACKGROUND: The relevance of destructive pyelonephritis in pediatric practice is determined by frequency of various complications of the disease associated with a high risk of irreversible morphofunctional changes in parenchyma of affected kidney, the lack of tactical consensus in the professional community and regulatory documents regulating the procedure for diagnostic and therapeutic support of this contingent of patients. AIM: Substantiation of the tactics of effective treatment children with destructive pyelonephritis, based on the results of a multifactorial retrospective analysis of the course and outcomes of the disease. MATERIALS AND METHODS: The results of the analysis of medical documentation of 38 patients with destructive pyelonephritis aged 3204 months (median 93.5) who received inpatient treatment in 20152019 in three specialized clinics in Moscow are presented. RESULTS: More than half of the patients (28 children) in the acute period of the disease received conservative therapy, including infusion and antibacterial, the escalation of which was carried out with the preservation or increase of manifestations of the systemic inflammatory response syndrome, as well as negative dynamics according to ultrasound or CT data. In the group of patients (n = 10), indications for surgical treatment were formulated decapsulation of the kidney, opening of apostemas and abscessed foci, drainage of the paranephral space. During the examination in catamnesis, realized in 50%. It was found that in the majority (91%) of children treated conservatively, a statistically significant decrease in the volume of the kidney on the affected side was registered. These complications were not detected among the operated patients. CONCLUSION: The pharmacy of choice for starting antibacterial therapy should be inhibitor-protected beta-lactams, carbapenems, if the etiological significance of staphylococcus is suspected, it is advisable to connect linezolid. In case of laboratory signs of hypercoagulation, it is necessary to connect anticoagulants. Surgical tactics can minimize the risk of complications associated with the purulent-destructive process, contributing to regenerative processes in the kidney parenchyma. The objectification of the results of the catamnestic examination is due to the performance of nephroscintigraphy.

2019 ◽  
Vol 19 (1-2) ◽  
pp. 140-148
Author(s):  
A. R Amirov ◽  
O. A Lobkarev ◽  
R. A Bodrova

Urinary incontinence is an unsolved problem in urology. Awareness of the predisposing risk factors and the etiology of urinary incontinence contributes to its prevention, to facilitate timely diagnosis and the choice of the correct tactics for the correction of urinary disorders. The main causes of incontinence may be dysfunction of the detrusor, its hyperactivity, hyperreflexia, low elasticity, disruption of the sphincter apparatus, paradoxical ishuria, and extraurethral incontinence. In the treatment of incontinence, it was originally recommended to use conservative therapy; in the absence of effect, one can think of surgical methods of treatment depending on the degree of the disorder. This review considers literature data on the identification of risk factors and etiology in the development of urinary incontinence.


GYNECOLOGY ◽  
2019 ◽  
Vol 21 (5) ◽  
pp. 12-15
Author(s):  
Anastasiia S Safronova ◽  
Mikhail Yu Vysokikh ◽  
Vladimir D Chuprynin ◽  
Natalia A Buralkina

There is currently no consensus on the etiopathogenetic nature of endometriosis. The causes of aggressive, progressive, infiltrative growth of endometrioid tissue also remain unclear. An important problem remains the high recurrence rate of endometriosis, despite the availability of modern drug and surgical methods of treatment. The study of the central signaling pathways and the search for new key molecules is of paramount importance for a better understanding of the pathogenesis of the disease, and is also an important step in the development of new strategies for the diagnosis, prevention and treatment of endometriosis.


2019 ◽  
Vol 65 (6) ◽  
pp. 868-876
Author(s):  
Anton Yarikov ◽  
Anton Yermolaev ◽  
Igor Smirnov ◽  
Anton Denisov ◽  
Olga Perlmutter ◽  
...  

Epidemiological studies show an increase in the number of people with cancer. Bone metastases are a frequent manifestation of generalized cancer, because it is in malignant tumors of the spine more often than other bones of the skeleton becomes a target for metastasis. The article describes in detail the methods of diagnosis of spinal lesions in cancer pathology. Particular attention is paid to the scales reflecting the severity of the patient’s condition, the degree of spinal cord damage, the severity of pain in metastasis to the spine, the prognosis of survival in oncovertebrology and evaluation of the stability of the spine in metastatic lesions. Further, the paper presents non-radical (decompression, vertebroplasty) and radical (spondylectomy, corporectomy) surgical methods of treatment


1927 ◽  
Vol 23 (4) ◽  
pp. 425-429
Author(s):  
N. S. Utochnikova

The treatment of inflammatory diseases of the female genitalia has long been one of the most important tasks of the gynecologist. With the development of surgery, surgical methods of treatment began to be applied: exudates were removed, the uterus and inflamed appendages were extirpated, etc.; but the danger of surgical intervention on the one hand, and on the other - the severe consequences of removal of organs such as ovaries, especially in young women - forced gynecologists to spend much effort in discovering and improving non-operative methods of treatment of inflammatory diseases of the female genital parts. Among these methods, physical methods such as water, mud, light baths, massage, etc., as well as those related to electricity have long been prominent.


2020 ◽  
Vol 5 (1) ◽  
pp. 37-39
Author(s):  
G. Cordy

The author praises the Thure Brandt's method of treatment diseases of female genital organs and says that he has come to the development of this method to such perfection that new work in this area can only be directed at the discovery of the newest information on the physiology and pathology of the female genital apparatus, for the Thure Brandt's method to be shown to the indications for method and the reason for his success. It is also known that in case of uterine prolapse, in old and neglected cases, this method of raising the uterus and massage can give an amazingly quick and perfect result, in other cases it is not. Obviously, failure is the result of various anatomical relationships, and, according to the author, the bending of the uterus back and its side positions, where pessaries and surgical methods of treatment are more intelligent.


2017 ◽  
pp. 43-48
Author(s):  
A. I. Nedozymovany ◽  
E. A. Dementeva ◽  
D. E. Popov ◽  
S. V. Vasiliev

Despite of lots conservative and surgical methods of treatment, the problem of anal incontinence is relevant today and remains unresolved. Since the beginning of the 1990s attempts ofimplantation of bulking agents in order to increase the basal pressure in the anal canal were begun. Domestic product “ДАМ+” used in the study. OBJECTIVE. To determine the indications for injection of bulking agents for the treatment of anal incontinence. Research the possibility of using the drug “ДАМ+,” with assessment of treatment outcomes. During a period of 2014 to 2016 there were 30 patients with anal incontinence of various etiologies involved in research. The mean age was 47,5 ± 6,5 years. Injection of bulking agent “ДАМ+” were performed by the punction of submucosa of the anal canal in 3 points, andfollowed by a comparative analysis of the survey after treatment. Average follow-up was 12,1 ± 0,97 months. The study we have identified indications for the implementation of bulking agents for correction of anal incontinence, and the estimation results.


2010 ◽  
Vol 9 (2) ◽  
pp. 99-101
Author(s):  
L. Ya. Kovalʹchuk ◽  
B. T. Stepan

1937 ◽  
Vol 33 (4) ◽  
pp. 490-491
Author(s):  
M. V. Dunier

The question of an internal hernia of the abdominal cavity is still little developed both from the anatomical and from the clinical side; as well as little developed surgical methods of treatment of these hernias.


Author(s):  
Niushen Zhang

The first-line treatment of trigeminal neuralgia can be very effective, but side effects are often difficult for patients to tolerate. This chapter is a guide to the broad selection of medical therapies currently available for the treatment of trigeminal neuralgia which includes oral therapies and other non-surgical methods of treatment such as IV medications, nasal sprays, topical ointments, and injections. The discussion of each treatment includes discussion of its evidence in current literature, its proposed mechanism of action, its dosing and appropriate setting for clinical use, and its side effect profile.


Author(s):  
Marissa Hagan ◽  
Ashit K. Shetty

‘Transient ischaemic attack (TIA) in the older person’ explores the new definitions of TIA (transient ischaemic attack) especially in the context of modern imaging methods, epidemiology of this common condition and its implications for everyone, the pathophysiology, common and less common clinical presentations, the differential diagnoses (including transient mono-ocular blindness, transient global amnesia, migraine, amyloid spells, and others), the risk factors (modifiable and non-modifiable), prognosis, risk scoring (ABCD2, ABCD2i, ABCD3i), investigation methods, and various pharmacological, non-pharmacological, and surgical methods of treatment. Lastly, this chapter discusses issues about TIA in the real world and the issues facing various stroke services around the world.


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