The Mackenzie Mountains EarthScope Project: Studying Active Deformation in the Northern North American Cordillera from Margin to Craton

2019 ◽  
Vol 91 (1) ◽  
pp. 521-532 ◽  
Author(s):  
Michael G. Baker ◽  
David C. Heath ◽  
Derek L. Schutt ◽  
Richard C. Aster ◽  
Joel F. Cubley ◽  
...  
Keyword(s):  
Michigan State University ◽  
Canadian Cordillera ◽  
State University ◽  
Geographic Variations ◽  
Active Deformation ◽  
North American Cordillera ◽  
Colorado State University ◽  
Mackenzie Mountains ◽  
The University

Abstract The Mackenzie Mountains EarthScope Project—a collaboration between Colorado State University, the University of Alaska, Michigan State University, and Yukon College—deployed a roughly linear, 40-station broadband seismographic network. This network crossed the actively deforming Northern Canadian Cordillera and the Mackenzie Mountains in Yukon, Canada; it also extended into the Canadian Shield in Northwest Territories, Canada. The array was deployed between July 2016 and August 2018 (with four pilot stations installed in July 2015 and three extended stations operating through August 2019) coinciding with and complementing the deployment of the EarthScope Transportable Array to Alaska and western Canada. In this article, we present an overview of project scientific objectives, station configurations, and site conditions; discuss environmental challenges, including those that resulted in station downtime (e.g., spring flooding and encounters with bears); and suggest potential solutions to such subarctic challenges for the benefit of future deployments in comparable regions. We also include an initial characterization of seasonal and geographic variations in ambient seismic noise for the northwestern Canadian Cordillera.

scholarly journals Preface: Modern Heterocycle Synthesis and Functionalization

Synlett ◽  
2021 ◽  
Vol 32 (02) ◽  
pp. 140-141
Author(s):  
Louis-Charles Campeau ◽  
Tomislav Rovis
Keyword(s):  
Active Pharmaceutical Ingredient ◽  
Associate Professor ◽  
Columbia University ◽  
State University ◽  
Heterocycle Synthesis ◽  
Colorado State University ◽  
University Of Toronto ◽  
Process Chemistry ◽  
The University ◽  
Small Molecule Therapeutics

obtained his PhD degree in 2008 with the late Professor Keith Fagnou at the University of Ottawa in Canada as an NSERC Doctoral Fellow. He then joined Merck Research Laboratories at Merck-Frosst in Montreal in 2007, making key contributions to the discovery of Doravirine (MK-1439) for which he received a Merck Special Achievement Award. In 2010, he moved from Quebec to New Jersey, where he has served in roles of increasing responsibility with Merck ever since. L.-C. is currently Executive Director and the Head of Process Chemistry and Discovery Process Chemistry organizations, leading a team of smart creative scientists developing innovative chemistry solutions in support of all discovery, pre-clinical and clinical active pharmaceutical ingredient deliveries for the entire Merck portfolio for small-molecule therapeutics. Over his tenure at Merck, L.-C. and his team have made important contributions to >40 clinical candidates and 4 commercial products to date. Tom Rovis was born in Zagreb in former Yugoslavia but was largely raised in southern Ontario, Canada. He earned his PhD degree at the University of Toronto (Canada) in 1998 under the direction of Professor Mark Lautens. From 1998–2000, he was an NSERC Postdoctoral Fellow at Harvard University (USA) with Professor David A. Evans. In 2000, he began his independent career at Colorado State University and was promoted in 2005 to Associate Professor and in 2008 to Professor. His group’s accomplishments have been recognized by a number of awards including an Arthur C. Cope Scholar, an NSF CAREER Award, a Fellow of the American Association for the Advancement of Science and a ­Katritzky Young Investigator in Heterocyclic Chemistry. In 2016, he moved to Columbia University where he is currently the Samuel Latham Mitchill Professor of Chemistry.

Stereocontrolled C-O Ring Construction: The Fuwa/Sasaki Synthesis of Attenol A

2011 ◽  
Author(s):  
Douglass Taber
Keyword(s):  
Gold Catalysis ◽  
Membered Ring ◽  
Allylic Alcohol ◽  
State University ◽  
Prins Cyclization ◽  
University Of Florida ◽  
University Of Pittsburgh ◽  
Colorado State University ◽  
Institute Of Technology ◽  
The University

Since five-membered ring ethers often do not show good selectivity on equilibration, single diastereomers are best formed under kinetic control. Aaron Aponick of the University of Florida demonstrated (Organic Lett. 2008, 10, 669) that under gold catalysis, the allylic alcohol 1 cyclized to 2 with remarkable diastereocontrol. Six-membered rings also formed with high cis stereocontrol. Ian Cumpstey of Stockholm University showed (Chem. Commun. 2008, 1246) that with protic acid, allylic acetates such as 3 cyclized with clean inversion at the allylic center, and concomitant debenzylation. J. Stephen Clark of the University of Glasgow found (J. Org. Chem. 2008, 73, 1040) that Rh catalyzed cyclization of 5 proceeded with high selectivity for insertion into Ha, leading to the alcohol 6. Saumen Hajra of the Indian Institute of Technology, Kharagpur took advantage (J. Org. Chem. 2008, 73, 3935) of the reactivity of the aldehyde of 7, effecting selective addition of 7 to 8, to deliver, after reduction, the lactone 9. Tomislav Rovis of Colorado State University observed (J. Org. Chem. 2008, 73, 612) that 10 could be cyclized selectively to either 11 or 12. Nadège Lubin-Germain, Jacques Uziel and Jacques Augé of the University of Cergy- Pontoise devised (Organic Lett. 2008, 10, 725) conditions for the indium-mediated coupling of glycosyl fluorides such as 13 with iodoalkynes such as 14 to give the axial C-glycoside 15. Katsukiyo Miura and Akira Hosomi of the University of Tsukuba employed (Chemistry Lett. 2008, 37, 270) Pt catalysis to effect in situ equilibration of the alkene 16 to the more stable regioisomer. Subsequent condensation with the aldehyde 17 led via Prins cyclization to the ether 18. Paul E. Floreancig of the University of Pittsburgh showed (Angew. Chem. Int. Ed. 2008, 47, 4184) that Prins cyclization could be also be initiated by oxidation of the benzyl ether 19 to the corresponding carbocation. Chan-Mo Yu of Sungkyunkwan University developed (Organic Lett. 2008, 10, 265) a stereocontrolled route to seven-membered ring ethers, by Pd-mediated stannylation of allenes such as 21, followed by condensation with an aldehyde.

Other Methods for Carbocyclic Construction: The Porco Synthesis of (-)-Hyperibone K

2013 ◽  
Author(s):  
Douglass F. Taber
Keyword(s):  
Oxidative Cyclization ◽  
Florida State University ◽  
State University ◽  
Colorado State University ◽  
Intramolecular Alkylation ◽  
University Of Wisconsin ◽  
Tokyo Institute ◽  
Institute Of Technology ◽  
University Of Bristol ◽  
The University

Varinder K. Aggarwal of the University of Bristol described (Angew. Chem. Int. Ed. 2010, 49, 6673) the conversion of the Sharpless-derived epoxide 1 into the cyclopropane 2. Christopher D. Bray of Queen Mary University of London established (Chem. Commun. 2010, 46, 5867) that the related conversion of 3 to 5 proceeded with high diastereocontrol. Javier Read de Alaniz of the University of California, Santa Barbara, extended (Angew. Chem. Int. Ed. 2010, 49, 9484) the Piancatelli rearrangement of a furyl carbinol 6 to allow inclusion of an amine 7, to give 8. Issa Yavari of Tarbiat Modares University described (Synlett 2010, 2293) the dimerization of 9 with an amine to give 10. Jeremy E. Wulff of the University of Victoria condensed (J. Org. Chem. 2010, 75, 6312) the dienone 11 with the commercial butadiene sulfone 12 to give the highly substituted cyclopentane 13. Robert M. Williams of Colorado State University showed (Tetrahedron Lett. 2010, 51, 6557) that the condensation of 14 with formaldehyde delivered the cyclopentanone 15 with high diastereocontrol. D. Srinivasa Reddy of Advinus Therapeutics devised (Tetrahedron Lett. 2010, 51, 5291) conditions for the tandem conjugate addition/intramolecular alkylation conversion of 16 to 17. Marie E. Krafft of Florida State University reported (Synlett 2010, 2583) a related intramolecular alkylation protocol. Takao Ikariya of the Tokyo Institute of Technology effected (J. Am. Chem. Soc. 2010, 132, 11414) the enantioselective Ru-mediated hydrogenation of bicyclic imides such as 18. This transformation worked equally well for three-, four-, five-, six-, and seven-membered rings. Stefan France of the Georgia Institute of Technology developed (Org. Lett. 2010, 12, 5684) a catalytic protocol for the homo-Nazarov rearrangement of the doubly activated cyclopropane 20 to the cyclohexanone 21. Richard P. Hsung of the University of Wisconsin effected (Org. Lett. 2010, 12, 5768) the highly diastereoselective rearrangement of the triene 22 to the cyclohexadiene 23. Strategies for polycyclic construction are also important. Sylvain Canesi of the Université de Québec devised (Org. Lett. 2010, 12, 4368) the oxidative cyclization of 24 to 25.

Enantioselective Synthesis of Alcohols and Amines: The Fujii/Ohno Synthesis of (+)-Lysergic Acid

2015 ◽  
Author(s):  
Douglass F. Taber
Keyword(s):  
Kinetic Resolution ◽  
Lysergic Acid ◽  
Enantioselective Synthesis ◽  
Amino Acid Derivative ◽  
State University ◽  
University Of Arkansas ◽  
Keto Ester ◽  
Colorado State University ◽  
Quaternary Center ◽  
The University

Ramón Gómez Arrayás and Juan C. Carretero of the Universidad Autónoma de Madrid effected (Chem. Commun. 2011, 47, 6701) enantioselective conjugate borylation of an unsaturated sulfone 1, leading to the alcohol 2. Robert E. Gawley of the University of Arkansas found (J. Am. Chem. Soc. 2011, 133, 19680) conditions for enantioselective ketone reduction that were selective enough to distinguish between the ethyl and propyl groups of 3 to give 4. Vicente Gotor of the Universidad de Oviedo used (Angew. Chem. Int. Ed. 2011, 50, 8387) an overexpressed Baeyer-Villiger monoxygenase to prepare 6 by dynamic kinetic resolution of 5. Li Deng of Brandeis University prepared (J. Am. Chem. Soc. 2011, 133, 12458) 8 in high ee by kinetic enantioselective migration of the alkene of racemic 7. Bernhard Breit of the Freiburg Institute for Advanced Studies established (J. Am. Chem. Soc. 2011, 133, 20746) the oxygenated quaternary center of 10 by the addition of benzoic acid to the allene 9. Keith R. Fandrick of Boehringer Ingelheim constructed (J. Am. Chem. Soc. 2011, 133, 10332) the oxygenated quaternary center of 13 by enantioselective addition of the propargylic nucleophile 12 to 11. Yian Shi of Colorado State University devised (J. Am. Chem. Soc. 2011, 133, 12914) conditions for the enantioselective transamination of the α-keto ester 14 to the amine 15. Professor Deng added (Adv. Synth. Catal. 2011, 353, 3123) 18 to an enone 17 to give the protected amine 19. Song Ye of the Institute of Chemistry, Beijing effected (J. Am. Chem. Soc. 2011, 133, 15894) elimination/addition of an unsaturated acid chloride 20 to give the γ-amino acid derivative 22. Frank Glorius of the Universität Münster added (Angew. Chem. Int. Ed. 2011, 50, 1410) an aldehyde 23 to 24 to give the amide 25. Sentaro Okamoto of Kanagawa University designed (J. Org. Chem. 2011, 76, 6678) an organocatalyst for the enantioselective Steglich rearrangement of 26, creating the aminated quaternary center of 27. Most impressive of all was the report (Org. Lett. 2011, 13, 5460) by Hélène Lebel of the Université de Montréal of the direct enantioselective C–H amination of 28 to give 29.

C–O Ring Formation

2017 ◽  
Author(s):  
Tristan H. Lambert
Keyword(s):  
Science And Technology ◽  
State University ◽  
University Of Michigan ◽  
Colorado State University ◽  
Boston University ◽  
Chapel Hill ◽  
Chiral Phosphoric Acid ◽  
National University ◽  
University Of Bristol ◽  
The University

The enantioselective bromocyclization of dicarbonyl 1 to form dihydrofuran 3 using thiocarbamate catalyst 2 was developed (Angew. Chem. Int. Ed. 2013, 52, 8597) by Ying-Yeung Yeung at the National University of Singapore. Access to dihydrofuran 5 from the cyclic boronic acid 4 and salicylaldehyde via a morpholine-mediated Petasis borono-Mannich reaction was reported (Org. Lett. 2013, 15, 5944) by Xian-Jin Yang at East China University of Science and Technology and Jun Yang at the Shanghai Institute of Organic Chemistry. Chiral phosphoric acid 7 was shown (Angew. Chem. Int. Ed. 2013, 52, 13593) by Jianwei Sun at the Hong Kong University of Science and Technology to catalyze the enantioselective acetalization of diol 6 to form tetrahydrofuran 8 with high stereoselectivity. Jan Deska at the University of Cologne reported (Org. Lett. 2013, 15, 5998) the conversion of glutarate ether 9 to enantiopure tetrahy­drofuranone 10 by way of an enzymatic desymmetrization/oxonium ylide rearrange­ment sequence. Perali Ramu Sridhar at the University of Hyderabad demonstrated (Org. Lett. 2013, 15, 4474) the ring-contraction of spirocyclopropane tetrahydropyran 11 to produce tetrahydrofuran 12. Michael A. Kerr at the University of Western Ontario reported (Org. Lett. 2013, 15, 4838) that cyclopropane hemimalonate 13 underwent conver­sion to vinylbutanolide 14 in the presence of LiCl and Me₃N•HCl under microwave irradiation. Eric M. Ferreira at Colorado State University developed (J. Am. Chem. Soc. 2013, 135, 17266) the platinum-catalyzed bisheterocyclization of alkyne diol 15 to fur­nish the bisheterocycle 16. Chiral sulfur ylides such as 17, which can be synthesized easily and cheaply, were shown (J. Am. Chem. Soc. 2013, 135, 11951) by Eoghan M. McGarrigle at the University of Bristol and University College Dublin and Varinder K. Aggarwal at the University of Bristol to stereoselectively epoxidize a variety of alde­hydes, as exemplified by 18. The amine 20-catalyzed tandem heteroconjugate addition/Michael reaction of quinol 19 and cinnamaldehyde to produce bicycle 21 with very high ee was reported (Chem. Sci. 2013, 4, 2828) by Jeffrey S. Johnson at the University of North Carolina, Chapel Hill. Quinol ether 22 underwent facile photorearrangement–cycloaddition to 23 under irradiation, as reported (J. Am. Chem. Soc. 2013, 135, 17978) by John A. Porco, Jr. at Boston University and Corey R. J. Stephenson, now at the University of Michigan.

Lessons Learned About Outreach and Engagement at the Michigan State University Institute for the Study of Youth Sports

2017 ◽  
Vol 6 (4) ◽  
pp. 303-310 ◽  
Author(s):  
Daniel Gould
Keyword(s):  
Youth Sports ◽  
Community Outreach ◽  
Sports Participation ◽  
Lessons Learned ◽  
Social Effects ◽  
Michigan State University ◽  
State University ◽  
The Face ◽  
The University

The mission of the Institute for the Study of Youth Sports (ISYS) is to provide leadership, scholarship, and outreach that “transforms” the face of youth sports in ways that maximize the beneficial physical, psychological, and social effects of participation for children and youth while minimizing detrimental effects. Since its inception in 1978, ISYS has partnered with numerous organizations to promote healthy youth sports participation. In this article, the general steps ISYS takes to form and facilitate partnerships are addressed. Four long-term partnerships are also described. The services provided to these organizations are described and the advantages and challenges of working with partners, in general, are delineated. How these partnerships are used to facilitate the teaching, outreach-engagement, and scholarship components of the Michigan State University land grant mission are also described. The case of ISYS shows that conducting community outreach and engagement projects greatly enhance the scholarly mission of the university.

Book Reviews

2015 ◽  
Vol 53 (1) ◽  
pp. 118-119
Keyword(s):  
Institutional Economics ◽  
Michigan State University ◽  
State University ◽  
James Madison ◽  
John Maynard Keynes ◽  
Thorstein Veblen ◽  
Classical Economics ◽  
Self Sufficiency ◽  
The University ◽  
Political Economic

Theodore Burczak of Denison University reviews “Documents Related to John Maynard Keynes, Institutionalism at Chicago and Frank H. Knight”, by Ross B. Emmett. The Econlit abstract of this book begins: “Eight papers explore topics related to John Maynard Keynes, institutionalism at the University of Chicago, and Frank H. Knight. Papers discuss the original 1933 “National Self-Sufficiency” lecture by Keynes—its political economic context and purpose (Mark C. Nolan); “National Self-Sufficiency” (Keynes); studying institutional economics at Chicago in the 1930s—the case of Arthur Bloomfield (Pier Francesco Asso and Luca Fiorito); Thorstein Veblen and his analysis of business enterprise (Bloomfield); Knight on institutionalism and economics (Ross B. Emmett); institutional history and the classical economics (Knight); the friendship of Knight and Frederick D. Kershner (Emmett); and the correspondence between Knight and Kershner, 1915-51 (Emmett). Emmett is at James Madison College at Michigan State University.”

scholarly journals Cooperation, Collaboration and Coordination: Education Librarians in Michigan

2017 ◽  
Vol 22 (3) ◽  
pp. 13
Author(s):  
Katherine Corby ◽  
Shellie Jeffries ◽  
Darlene P. Nichols
Keyword(s):  
Michigan State University ◽  
Institutional Changes ◽  
State University ◽  
University Of Michigan ◽  
Education Programs ◽  
Research Libraries ◽  
Wayne State University ◽  
Level Of Activity ◽  
Economic Forces ◽  
The University

Formation of the Michigan Research Libraries Triangle consortium in 1991 served to bring the education librarians of Michigan State University, the University of Michigan and Wayne State University into a working relationship. The education programs at each institution have unique histories shaped by demographic, political and economic forces. The evolution of the programs profoundly influenced the physical and philosophical development of the education libraries at each institution and the education librarians have based their cooperation on the historic roles and unique strengths of each library 's collection. The level of activity and opportunityfor cooperation has fluctuated over the years due to institutional changes. 

scholarly journals Reviewer Acknowledgements

2017 ◽  
Vol 6 (1) ◽  
pp. 169
Author(s):  
Robert Smith
Keyword(s):  
Education And Training ◽  
Economic Research ◽  
Michigan State University ◽  
State University ◽  
American University ◽  
Kwazulu Natal ◽  
National University ◽  
The University ◽  
And Training

Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 6, Number 1Brenda L. Shook, National University, USACagla Atmaca, Pamukkale University, TurkeyCarole Fern Todhunter, The University of Nottingham, UKCharlotte Alverson, University of Oregon, USAChosang Tendhar, Long Island University (LIU), USAEnisa Mede, Bahcesehir University, TurkeyErica D. Shifflet-Chila, Michigan State University, USAGreg Rickwood, Nipissing University, CanadaHyesoo Yoo, Virginia Tech., USAIoannis Syrmpas, University of Thessaly, GreeceJohn Cowan, Edinburgh Napier University, UKLinda J. Rappel, Yorkville University/University of Calgary, CanadaMan-fung Lo, The Hong Kong Polytechnic University, Hong KongMassimiliano Barattucci, Ecampus University, ItalyMaurizio Sajeva, Pellervo Economic Research PTT, FinlandMehmet Inan, Marmara University, TurkeyMichail Kalogiannakis, University of Crete, GreeceMin Gui, Wuhan University, ChinaNerina Fernanda Sarthou, Universidad Nacional del Centro de la Provincia de Buenos Aires, ArgentinaPirkko Siklander, University of Lapland, FinlandRichard H. Martin, Mercer University, USARichard Penny, University of Washington Bothell, USARiyadh Tariq Kadhim Al-Ameedi, Babylon University, IraqRufaidah Kamal Abdulmajeed, Baghdad University, IraqSadia Batool, Preston University Islamabad, PakistanSelloane Pitikoe, University of Kwazulu-Natal, South AfricaSenem Seda Şahenk Erkan, Marmara University, TurkeySeyyedeh Mina Hamedi, Ferdowsi University of Mashhad, IranSisi Chen, American University of Health Sciences, USATilanka Chandrasekera, Oklahoma State University, USAYalçın Dilekli, Aksaray University, TurkeyYerlan Seisenbekov, Kazakh National Pedagogical University, KazakhstanYi Lu, American Institute for Research, USAYuChun Chen, Louisiana Tech University, USARobert SmithEditorial AssistantOn behalf of,The Editorial Board of Journal of Education and Training StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://jets.redfame.com

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