scholarly journals Ginsenoside content in suspension cultures of Panax quinquefolium L. cultivated in shake flasksand stirred-tank bioreactor

2018 ◽  
Vol 72 (1) ◽  
pp. 15 ◽  
Author(s):  
Ewa Kochan ◽  
Sylwia Caban ◽  
Grażyna Szymańska ◽  
Piotr Szymczyk ◽  
Anna Lipert ◽  
...  
Keyword(s):  
Large Scale ◽  
Raw Materials ◽  
Scale Up ◽  
Fold Increase ◽  
Suspension Cultures ◽  
Stirred Tank ◽  
Small Scale ◽  
Panax Quinquefolium ◽  
Stirred Tank Bioreactor ◽  
Shake Flasks

<p>Plant suspension cultures are described as a source for the acquisition of medicinal secondary metabolites which in the future may become an alternative to traditional raw materials. This study demonstrates that the cell cultures of one of the ginseng species – Panax quinquefolium L. synthesize ginsenosides, which are triterpene saponins having a multidirectional pharmacological effects. Tested suspension cultures were run on a small scale in the shake flasksand in scale up of the process in a 10-liter stirred tank. In the shake flasks,the highest biomass yield (2.28 gl-1 for dry and 33.99 gl-1 for fresh weight) was reached on day 30 of culture, and the highest content of saponins (2.66 mg g -1 dw) was determined on day 28 of culture. In the bioreactor, nearly 2.67 and 3-fold increase of respectively dry and fresh biomass was recorded in relation to the inoculum. Large-scale cultures synthesized protopanaxatriol derivatives such as Rg1 and Re ginsenosides, however, no saponins belonging to the protopanaxadiol derivatives were reported.</p>

scholarly journals Isoflavone production in Cyclopia subternata Vogel (honeybush) suspension cultures grown in shake flasks and stirred-tank bioreactor

2013 ◽  
Vol 97 (19) ◽  
pp. 8467-8477 ◽  
Author(s):  
Adam Kokotkiewicz ◽  
Maria Luczkiewicz ◽  
Wiktor Kowalski ◽  
Anna Badura ◽  
Natalia Piekus ◽  
...  
Keyword(s):  
Suspension Cultures ◽  
Stirred Tank ◽  
Stirred Tank Bioreactor ◽  
Shake Flasks

Scale‐up processing with different microparticle agent for β‐mannanase production in a large‐scale stirred tank bioreactor

2020 ◽  
Author(s):  
Hilal Nur Gürler ◽  
Selime Benemir Erkan ◽  
Ali Ozcan ◽  
Cansu Yılmazer ◽  
Ercan Karahalil ◽  
...  
Keyword(s):  
Large Scale ◽  
Scale Up ◽  
Stirred Tank ◽  
Stirred Tank Bioreactor

Monoterpenoid Oxindole Alkaloid Production by Uncaria tomentosa (Willd) D.C. Cell Suspension Cultures in a Stirred Tank Bioreactor

2008 ◽  
Vol 21 (3) ◽  
pp. 786-792 ◽  
Author(s):  
Gabriela Trejo-Tapia ◽  
Carlos M. Cerda-García-Rojas ◽  
Mario Rodríguez-Monroy ◽  
Ana C. Ramos-Valdivia
Keyword(s):  
Cell Suspension ◽  
Cell Suspension Cultures ◽  
Suspension Cultures ◽  
Stirred Tank ◽  
Alkaloid Production ◽  
Stirred Tank Bioreactor ◽  
Uncaria Tomentosa

scholarly journals ANALYSIS OF THE FUCTIONAL ROLE OF RICE MILLING COMPANY ON THE WELFARE OF RICE FARMERS IN THE SUB-DISTRICT BUAY MADANG TIMUR DISTRICT OKU TIMUR

Jurnal AKTUAL ◽  
2019 ◽  
Vol 16 (1) ◽  
pp. 47
Author(s):  
Aisah Aisah
Keyword(s):  
Large Scale ◽  
Raw Materials ◽  
Small Scale ◽  
Functional Roles ◽  
Medium Scale ◽  
Rice Farmers ◽  
Result Show ◽  
Rice Milling ◽  
Processing And Storage

Rice Milling Company is rice industry’s oldest and largest classified in Indonesia, which is able to absorb more than 10 million workers, handles more than 40 million tons of grain.  Rice Milling Company agro-industy is the central point, because this is where the main product is obtained in the form of rice and raw materials for advanced processing of food and industrial products.  Rice Miling Unit in the district of OKU Timur there is some skala, ranging form small-scale, medium-scale to large-scale.  Fuctional benefits of each different scale milling is also different.  The average rice farmers often sell gabahnya to the rice milling unit closest to the place residence, whether it is large-scale, medium and small.  Rice produced by the milling-grinding different quality.  Usually when a large-scale millimg yield of rice is cleaner than the other scale.  But it does not become a reference for milling grain milling usually depends on consumer demand.  The purpose of the study are : 1.  To determine levels of volume (tonnage) and the retention time of each service fuctional rice storage (barns) wich carried a different scale rice milling unit.  2.  To determine differences in the bebefits of economic transactions received by farmers and rice millers of different scale of business, especially when seen from the level of the milling costs, the purchase price of rice by rice milling unit, and the quality of milling services and service scale.  The result show that : the fuctional role of each is different milling.  Large-scale milling has three fuctional roles are : Processing, storage and distribution.  Medium-scale miling functional has two roles, namely : processing and distribution.  While small-scale rice milling unit has only two functional roles are : processing and storage.

scholarly journals Combined measurement of velocity and temperature in liquid metal convection

2019 ◽  
Vol 876 ◽  
pp. 1108-1128 ◽  
Author(s):  
Till Zürner ◽  
Felix Schindler ◽  
Tobias Vogt ◽  
Sven Eckert ◽  
Jörg Schumacher
Keyword(s):  
Reynolds Number ◽  
Liquid Metal ◽  
Large Scale ◽  
Scale Up ◽  
Convection Cell ◽  
Small Scale ◽  
Convection Flow ◽  
Large Scale Circulation ◽  
Large Scale Flow ◽  
The Impact

Combined measurements of velocity components and temperature in a turbulent Rayleigh–Bénard convection flow at a low Prandtl number of $Pr=0.029$ and Rayleigh numbers of $10^{6}\leqslant Ra\leqslant 6\times 10^{7}$ are conducted in a series of experiments with durations of more than a thousand free-fall time units. Multiple crossing ultrasound beam lines and an array of thermocouples at mid-height allow for a detailed analysis and characterization of the complex three-dimensional dynamics of the single large-scale circulation roll in a cylindrical convection cell of unit aspect ratio which is filled with the liquid metal alloy GaInSn. We measure the internal temporal correlations of the complex large-scale flow and distinguish between short-term oscillations associated with a sloshing motion in the mid-plane as well as varying orientation angles of the velocity close to the top/bottom plates and the slow azimuthal drift of the mean orientation of the roll as a whole that proceeds on a time scale up to a hundred times slower. The coherent large-scale circulation drives a vigorous turbulence in the whole cell that is quantified by direct Reynolds number measurements at different locations in the cell. The velocity increment statistics in the bulk of the cell displays characteristic properties of intermittent small-scale fluid turbulence. We also show that the impact of the symmetry-breaking large-scale flow persists to small-scale velocity fluctuations thus preventing the establishment of fully isotropic turbulence in the cell centre. Reynolds number amplitudes depend sensitively on beam-line position in the cell such that different definitions have to be compared. The global momentum and heat transfer scalings with Rayleigh number are found to agree with those of direct numerical simulations and other laboratory experiments.

Radial Profiles of Particle Velocity in a Large Scale CFB Downer

2004 ◽  
Vol 2 (1) ◽  
Author(s):  
Zhen Qian ◽  
Minghui Zhang ◽  
Hao Yu ◽  
Fei Wei
Keyword(s):  
Particle Velocity ◽  
Large Scale ◽  
Circulating Fluidized Bed ◽  
Scale Up ◽  
Radial Profile ◽  
Small Scale ◽  
Wall Region ◽  
Radial Profiles ◽  
Peak Value ◽  
Near Wall

Radial profiles of particle velocity in a large scale (418 mm I.D.) downward Circulating Fluidized Bed (CFB downer) were obtained via a Laser Doppler Velocimetry (LDV) system. Results show that particle velocity is gradually increasing along the radial direction and there exists a peak value in the near wall region. Such unique radial profile shape can be explained by the solids accumulating trend in the near wall region of the downer. Experiment results in this large scale downer are also compared with those obtained by other researchers in small scale units so as to investigate the scale-up effect on the radial particle velocity distribution in the downer.

scholarly journals Inulinolytic activity of broths ofAspergillus nigerATCC 204447 cultivated in shake flasks and stirred tank bioreactor

2017 ◽  
Vol 17 (9) ◽  
pp. 1006-1020 ◽  
Author(s):  
Anna Kowalska ◽  
Anna Antecka ◽  
Piotr Owczarz ◽  
Marcin Bizukojć
Keyword(s):  
Stirred Tank ◽  
Stirred Tank Bioreactor ◽  
Shake Flasks
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