scholarly journals Effects of oophorectomy on the lumbar spine of Wistar rats submitted to vibratory platform treatment

2020 ◽  
Vol 37 (5) ◽  
pp. 318-325
Author(s):  
AL de Freitas Tavares ◽  
AL Peretti ◽  
CM Martin Kakihata ◽  
M Neves ◽  
CG Brandão ◽  
...  

Introduction: This study evaluated the effect of the vibratory platform on the lumbar spine morphology of Wistar rats submitted to hormonal deprivation by oophorectomy. Material and method: Twenty rats were divided into four groups: Pseudo-oophorectomy (GP), Pseudo-oophorectomy Treated (GPT), Oophorectomy (GO), Oophorectomy Treated (GOT). After 60 days of postoperative, the treated groups started exercises on a vibratory platform in the frequency parameters of 60 Hz, alternating vibration with amplitude of 2 mm, acceleration of 57.6 m/s² and time of 10 minutes, three times in the during the four week period. Following the euthanasia of the animals, the lumbar spine was dissected and processed for analysis of the anterior and posterior longitudinal ligaments, intervertebral disc height (IVD), nucleus pulposus (NP) height, radiographic density of the lumbar vertebrae and IVD morphology. Results: The results showed a decrease in the height of the NP associated to the GO and morphological alterations such as lamellar disorganization and presence of rifts in the fibrous ring, alterations of the structural limits and decrease of the NP cavity; while the other groups presented organized lamellae, peripheral and nuclear region well delimited and wide cavity of the nucleus. Conclusion: In this way, it can be concluded that the oophorectomy protocol promoted a decrease in the height of the NP of the IVD and that the exercise in the vibratory platform did not generate lesions in the analyzed tissues, as well as preserved the structural organization of the IVD and the height of the NP of oophorectomized rats.

2021 ◽  
pp. 219256822199668
Author(s):  
Yusuke Murakami ◽  
Tadao Morino ◽  
Masayuki Hino ◽  
Hiroshi Misaki ◽  
Hiroshi Imai ◽  
...  

Study Design: Retrospective observational study. Objective: To investigate the relationship between the extent of ligament ossification and the range of motion (ROM) of the lumbar spine and develop a new scoring system. Methods: Forty-three patients (30 men and 13 women) with lumbar spinal canal stenosis who underwent decompression from January to December 2018. Ligament ossification at L1/2 to L5/S was assessed on plain X-ray (Xp) and computed tomography (CT) using a modified Mata scoring system (0 point: no ossification, 1 point: ossification of less than half of the intervertebral disc height, 2 points: ossification of half or more of the intervertebral disc height, 3 points: complete bridging), and the intra-rater and inter-rater reliability of the scoring was assessed. The relationship of the scores with postoperative lumbar ROM was investigated. Result: Intra-rater reliability was high (Cronbach’s α was 0.74 for L5/S on Xp but 0.8 or above for other sections), as was inter-rater reliability (Cronbach’s α was 0.8 or above for all the segments). ROM significantly decreased as the score increased (scores 1 to 2, and 2 to 3). A significant moderate negative correlation was found between the sum of the scores at L1/2-L5/S and the ROM at L1-S (ρ = − 0.4493, P = 0.025). Conclusion: Our scoring system reflects lumbar mobility and is reproducible. It is effective for assessing DISH in fractures and spinal conditions, and monitoring effects on treatment outcomes and changes over time.


Spine ◽  
2016 ◽  
Vol 41 (24) ◽  
pp. 1917-1924 ◽  
Author(s):  
Douglas G. Chang ◽  
Robert M. Healey ◽  
Alexander J. Snyder ◽  
Jojo V. Sayson ◽  
Brandon R. Macias ◽  
...  

Author(s):  
Anna L. Falkowski ◽  
Balazs K. Kovacs ◽  
Robyn M. Benz ◽  
Patrick Tobler ◽  
Stephan Schön ◽  
...  

Abstract Objectives Supine lumbar spine examinations underestimate body weight effects on neuroforaminal size. Therefore, our purpose was to evaluate size changes of the lumbar neuroforamina using supine and upright 3D tomography and to initially assess image quality compared with computed tomography (CT). Methods The lumbar spines were prospectively scanned in 48 patients in upright (3D tomographic twin robotic X-ray) and supine (30 with 3D tomography, 18 with CT) position. Cross-sectional area (CSA), cranio-caudal (CC), and ventro-dorsal (VD) diameters of foramina were measured by two readers and additionally graded in relation to the intervertebral disc height. Visibility of bone/soft tissue structures and image quality were assessed independently on a 5-point Likert scale for the 18 patients scanned with both modalities. Descriptive statistics, Wilcoxon’s signed-rank test (p < 0.05), and interreader reliability were calculated. Results Neuroforaminal size significantly decreased at all levels for both readers from the supine (normal intervertebral disc height; CSA 1.25 ± 0.32 cm2; CC 1.84 ± 0.24 cm2; VD 0.88 ± 0.16 cm2) to upright position (CSA 1.12 ± 0.34 cm2; CC 1.78 ± 0.24 cm2; VD 0.83 ± 0.16 cm2; each p < 0.001). Decrease in intervertebral disc height correlated with decrease in foraminal size (supine: CSA 0.88 ± 0.34 cm2; CC 1.39 ± 0.33 cm2; VD 0.87 ± 0.26 cm2; upright: CSA 0.83 ± 0.37 cm2, p = 0.010; CC 1.32 ± 0.33 cm2, p = 0.015; VD 0.80 ± 0.21 cm2, p = 0.021). Interreader reliability for area was fair to excellent (0.51–0.89) with a wide range for cranio-caudal (0.32–0.74) and ventro-dorsal (0.03–0.70) distances. Image quality was superior for CT compared with that for 3D tomography (p < 0.001; κ, CT = 0.66–0.92/3D tomography = 0.51–1.00). Conclusions The size of the lumbar foramina is smaller in the upright weight-bearing position compared with that in the supine position. Image quality, especially nerve root delineation, is inferior using 3D tomography compared to CT. Key Points • Weight-bearing examination demonstrates a decrease of the neuroforaminal size. • Patients with higher decrease in intervertebral disc showed a narrower foraminal size. • Image quality is superior with CT compared to 3D tomographic twin robotic X-ray at the lumbar spine.


2021 ◽  
Author(s):  
Xiaolong Chen ◽  
Stone Sima ◽  
Harvinder Sandhu ◽  
Jeff Kuan ◽  
Ashish Diwan

Purpose: To evaluate intra- and inter-rater agreement and reliability of seven reported disc height index (DHI) measurement methods on standing lateral X-ray of lumbar spine. Methods: The adult patients who had standing lateral X-ray of lumbar spine were recruited. Seven methods were used to measure DHI of each lumbar intervertebral disc level. Bland and Altman Limits of Agreement (LOA) with standard difference were calculated to examine intra- and inter-rater agreements between two out of seven methods for DHI. Intra-class correlations (ICC) with 95% confidence intervals were calculated to assess intra- and inter-rater reliability. Results: The intra-rater reliability in DHI measurements for 288 participants were ICCs from 0.807 (0.794, 0.812) to 0.922 (0.913, 0.946) by rater 1 (SS) and from 0.827 (0.802, 0.841) to 0.918 (0.806, 0.823) by rater 2 (XC). Method 2, 3, and 5 on all segmental levels had bias (95% CI does not include zero) or/and out of the acceptable cut-off proportion (>50%). A total of 609 outliers in 9174 segmental levels LOA range. Inter-rater reliability was good-to-excellent in all but method 2 (0.736 (0.712, 0.759)) and method 5 (0.634 (0.598, 0.667)). ICCs of related lines to good-to-excellent reliability methods was excellent in all but only indirect line in method 1 and 4 (ICCs lie in the range from 0.8 to 0.9). Conclusion: Following structured protocol, intra- and inter-rater reliability was good-to-excellent for most DHI measurement methods on X-ray. However, in the presence of vertebral rotation, one should exercise caution in using complicated methods to define vertebral landmarks. Keywords: Lumbar disc herniation, discectomy, disc height, disc height index, agreement, reliability.


Spine ◽  
2001 ◽  
Vol 26 (19) ◽  
pp. 2112-2118 ◽  
Author(s):  
Kazuhiro Chiba ◽  
Yoshiaki Toyama ◽  
Morio Matsumoto ◽  
Hirofumi Maruiwa ◽  
Masahiko Watanabe ◽  
...  

Author(s):  
Nina Korbozerova ◽  
Olena Obruchnikova

Complex attributive sentences in the Spanish language of the medieval period are characterized by a vague expression of the degree of syntactic subordination. During the XII-XVI centuries there is a process of constant enrichment of meanings and forms of complex attributive sentences. The final formation of the structural organization of a complex attributive sentence ended in the XVII century, in the period of unification and formation of the national Spanish language. Starting from the Old Spanish period, the externally formal homogeneity of models of a complex attributive sentence is disturbed by deep internal complications of semantic connections between the main and subordinate parts. Thus, in the Middle Spanish period, a complex attributive sentence gradually reformatted its structural organization by strengthening the contact position of the nominal center of subordination with the conjunctions and strengthening bilateral links between predicative components, which further contributed to the normalization of the position of the subordinate part. On the other hand, there is an intensive mutual replacement of some conjunctions with others. In the Old Spanish period, the conjunctions bigan to lose their uncoordinated lexical correlation between the correlative word and the supporting noun in the main part. This trend contributed to the consolidation of the structural organization of a complex attributive sentence, which was realized in the early Spanish period.


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