scholarly journals Drug utilization study in diabetic patients seeking medical treatment in a north Indian rural medical college hospital

2018 ◽  
Vol 7 (5) ◽  
pp. 912
Author(s):  
Shweta Sharma ◽  
S. C. Chopra ◽  
D. K. Sharma ◽  
Juhi Singla ◽  
Vinod Kapoor
Keyword(s):  
Chronic Disease ◽  
Drug Utilization ◽  
Demographic Data ◽  
Tertiary Care ◽  
General Medicine ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Diabetic Patients ◽  
Care Hospital ◽  
College Hospital

Background: Diabetes Mellitus is a chronic disease and its life-long management causes burden on lifestyle and financial condition of the patients. Drug utilization studies provide useful insights into the current prescribing practices.Methods: To evaluate the drug utilization pattern of anti-diabetic drugs in diabetic patients. A prospective observational study was carried out in adult diabetic patients visiting the Wards and Outpatient Department of General Medicine of a tertiary care hospital. The demographic data and utilization of different classes of anti-diabetic agents as well as individual drugs were analyzed.Results: In 125 patients (Male-65, Female-60), a total of 379 drugs (average 3.032±2.05) were used per day, out of which 76 (20.05%) were rational fixed dose combinations (FDCs) and 261 (68.86%) were prescribed from National List of Essential Medicines (NLEM) 2015. The number of drugs prescribed to be ingested was 326 (86.01%) and 63 (16.62%) were injectables.Conclusions: It was found that the prescription tendencies of the doctors were quite rational. More improvement can be done by sensitizing them to prescribe more drugs from NLEM. The limitations in the affordability of rural population should be taken care of while prescribing drugs for this chronic disease.

scholarly journals A Drug Utilisation Study of Antihyperglycaemic Agents in a Rural Tertiary Care Hospital

2017 ◽  
Vol 6 (1) ◽  
pp. 1357
Author(s):  
Naidu CDM ◽  
Vardhan A ◽  
Bankar MA ◽  
Sharma S ◽  
Raghuvanshi VS ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Demographic Data ◽  
Tertiary Care ◽  
General Medicine ◽  
Diabetic Patients ◽  
Defined Daily Dose ◽  
Care Hospital ◽  
Utilization Pattern

<p><strong>Background</strong>: Diabetes mellitus is an emerging non communicable, life style disease. The aim was to evaluate the drug utilization pattern of anti-diabetic drugs in diabetic outpatients and monitor the adverse drug reactions (ADRs) associated with anti-diabetic therapy.</p><p><strong>Materials and</strong> <strong>methods</strong>: A prospective observational study was carried out in adult diabetic patients from the Department of General Medicine of a rural tertiary care hospital in October 2013- December 2014 after obtaining written informed consent from the patient and approval from institutional ethics committee. Demographic data, drug utilization pattern, cost of the antidiabetic drugs along with defined daily dose was calculated. ADRs due to anti-diabetic drugs were summarized.</p><p><strong>Results</strong>: A total of 450 patients were enrolled in the study of which there was male preponderance and majority belong to geriatric age. The most common comorbidity was hypertension. Insulin was most commonly prescribed drug during hospital stay and metformin at the time of discharge. Of the combination therapy dual therapy of metformin and glimipiride was most preferred. The total antihyperglycaemic drug consumption was 15.65 DDD/100 bed days. 67 ADR were reported of which the most common was hypoglycaemia.</p><p><strong>Conclusions</strong>: The study showed insulin and metformin were the most commonly used drugs. The prescribing trend also appears to be moving towards combination therapy particularly two drug therapies. The most commonly reported ADR was hypoglycaemia.</p>

scholarly journals Pattern of Cardiovascular Drugs Use in Outpatient Department in a Tertiary Care Hospital of Bangladesh

2018 ◽  
Vol 32 (2) ◽  
pp. 65-69
Author(s):  
Udoy Shankar Roy ◽  
AKM Monwarul Islam ◽  
Mohsin Ahmed ◽  
Murshidur Rahman Khan ◽  
Nihar Ranjan Sarker
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cardiovascular Drugs ◽  
Medical College Hospital ◽  
Outpatient Department ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College

Objective: The objective of the present study was to provide recent population-based information on use of cardiovascular drugs in outpatients in a tertiary care hospital of Dhaka, Bangladesh.Methods: A prospective study of cardiovascular prescriptions of Outpatient Department of Department of Cardiology of Shaheed Suhrawardy Medical college hospital Dhaka, Bangladesh was carried out. A total of 215 prescriptions were collected for the study in Shaheed Suhrawardy Medical College Hospital Dhaka, Bangladesh from July 2015 to June 2016. The prescriptions were evaluated for rationality based on WHO model list of essential medicines. The prescriptions were critically analyzed using predetermined parameters.Results: Out of 215 prescriptions collected, 120 drugs were found to be repeatedly prescribed. The results revealed that all single dose formulations prescribed were rationally in accordance with WHO essential drug list whereas fixed dose combinations prescribed remain questionable. A pattern of polypharmacy was clearly evident.Conclusion: Medications are a critical modality for prolongation and improved quality of life. Campaign and intervention should be focused on patients with more than three diagnostic cardiovascular conditions in order to minimize polypharmacy in patients particularly elderly.Bangladesh Heart Journal 2017; 32(2) : 65-69

scholarly journals DRUG UTILIZATION PATTERN IN GERIATRIC PATIENTS ATTENDING OUT PATIENT DEPARTMENT AT RURAL TERTIARY CARE HOSPITAL IN MAHARASHTRA.

2017 ◽  
Vol 10 (2) ◽  
pp. 314
Author(s):  
Tushar B Nishandar ◽  
Anand S Kale ◽  
Harshal N Pise
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Drug Prescription ◽  
Demographic Data ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Essential Medicines ◽  
Care Hospital ◽  
Drug Prescribing ◽  
Prescription Pattern

Objective: To observe a prescription pattern in elderly patients attending outpatient department (OPD) and evaluating prescriptions according to theWorld Health Organization (WHO) prescription indicators.Methods: A cross-sectional observational study was conducted from July to September 2015. Patients of either gender, age 60 years or more, attending OPD in tertiary care hospital were included in the study. Prescriptions of medical practitioners were collected and evaluated for demographic data and the WHO drug prescribing indicators.Results: A total of 600 patients were enrolled in the study. The majority of the patients were in the age group 60-69 years (66.33%) with male preponderance (61%). The average number of drugs per prescription was 3.41. Out of 2045 drugs prescribed, 1261 drugs (61.66%) were prescribed by their generic name and 784 drugs (38.33%) were prescribed by their brand name. 1700 drugs (83.12%) prescribed were from the WHOs essential medicines list 2015. Total encounters involving injectable usage were 0.15%. Drugs acting on the cardiovascular system (21.12%) were the most frequently prescribed, followed by nonsteroidal anti-inflammatory drugs (NSAIDs) (20%). Ranitidine (16.62%) is the most frequently prescribed drug. Conclusions: In this study, drug prescription pattern was rational as per the WHO drug prescribing indicators. However, issues such as polypharmacy and inaccuracies of dose and duration were seen.Keywords: Drug utilization study, Geriatric, Outpatient department, Rational use of medicines.

scholarly journals Utilization trends of drugs in patients admitted with ischemic heart disease in a tertiary care teaching hospital

2020 ◽  
Vol 9 (6) ◽  
pp. 956
Author(s):  
Ayan Roy ◽  
Sashi Bhushan Biswal ◽  
Nayan Kumar Patel ◽  
Prajit Saswat Hota ◽  
Bhabagrahi Rath
Keyword(s):  
Drug Utilization ◽  
Angiotensin Receptor Blockers ◽  
Tertiary Care ◽  
Chronic Stable Angina ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Evidence Based ◽  
Care Hospital ◽  
Clinical Practices ◽  
Β Blockers

Background: Coronary artery disease (CAD) takes the highest toll of lives across the world as well as India. Prompt diagnosis and effective treatment is lifesaving. Drug utilization studies scrutinize the appropriateness of treatment and provide favourable feedbacks to strengthen clinical practices. Several other studies have reported underuse of four evidence-based medicines namely aspirin, β-blockers, angiotensin-converting enzyme inhibitors (ACE-I) or angiotensin receptor blockers (ARB), and statins in patients with CAD. Polypharmacy, injection overuse is some of the shortcomings. The objectives of this study was to describe treatment practices in terms of different disease spectrum and drug utilization (group-wise and individually) for inpatients with CAD using core prescription indicators by WHO.Methods: A cross-sectional study of 4-month duration was undertaken for patients with CAD admitted to cardiology indoor of a tertiary care hospital. A total no of 143 prescriptions was screened and analyzed.Results: Males (67.13%) were more in number than females (32.87%). Age group from (57-66) topped in frequency (61.05%) ahead of (67 to 76) group (38.46%). Average no of drugs per patient were 8.056±1.97 and 5.86±0.14 for cardiovascular drugs. Prescription in generics (45.49%), antibiotics (0.61%), fixed-dose combinations (FDCs) (0.52%) and injectables (28.47%) were noted. The most common categories of CAD were ST-segment elevated myocardial infarction (69.23%) followed by chronic stable angina (17.48%). Antiplatelets (100%), hypolipidemics (99.3%), antianginals (60.14%), β-blockers (37.06%) and ACE-I/ARBs (27.97%) were utilized. Drugs from the national list of essential medicines were 66.49%.Conclusions: Among four evidence-based drugs, use of β-blockers and ACE-I/ARBs were inappropriately low. Polypharmacy and overuse of Injectable drugs are noted.

scholarly journals Prescribing patterns of cardiovascular drugs in cardiology outpatient department in a tertiary care hospital in Western Odisha

2020 ◽  
Vol 10 (1) ◽  
pp. 23
Author(s):  
Ayan Roy ◽  
Nayan Kumar Patel
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cardiovascular Drugs ◽  
Prescribing Patterns ◽  
World Health ◽  
Fixed Dose ◽  
Care Hospital ◽  
Clinical Practices ◽  
Common Diagnosis

Background: Cardiovascular morbidity plays a villainous role globally as well as countries like India. Additionally, irrational prescription incurs greater damage to health and wellbeing. Drug utilization studies scrutinize the appropriateness of treatment and provide favorable feedbacks to strengthen clinical practices. The objective of the study was to describe treatment practices in cardiology outpatient and drug utilization pattern using core prescribing indicators by World Health Organization (WHO).Methods: A cross-sectional, observational study of 4-month duration was undertaken for cardiology Outdoor patients at a tertiary care hospital. 615 prescriptions were screened and analyzed.Results: Males (59.84%) were more in number than females (40.16%). Average number of the prescribed drugs per patient were 4.32±2.7 and (3.73±1.1 for cardiovascular drugs). Generic prescription was 60.98%. Percentage encounters with antibiotics 4.11, injectables 2.92%, fixed-dose combinations (FDCs) (11.8%) were documented. Drugs from the National List of Essential Medicines were 75.89%. The most common diagnosis was ischemic heart disease (68.29%). Hypolipidemics (78.25%) followed by antiplatelets (71.14%) were toppers in cardiovascular drug. Antiulcer drugs (PPI/Antacids) comprised 58.54% of total prescriptions.Conclusions: Less adherence to EDL, less generic prescriptions, use of FDC are major shortcomings. Areas to further rationalization like optimal use of evidence based medication like beta-blockers, newer anticoagulants/anti-platelet agents and newer anti-anginal agents are identified.

scholarly journals A PROSPECTIVE STUDY ON ANTIMICROBIAL UTILIZATION PATTERN IN OUTPATIENT DEPARTMENT AT TERTIARY CARE HOSPITAL, PUNE, INDIA.

2018 ◽  
Vol 11 (5) ◽  
pp. 131
Author(s):  
Sarang A Deshmukh ◽  
Yashasvi Agarwal ◽  
Harshita Hiran ◽  
Uma Bhosale
Keyword(s):  
Antimicrobial Agents ◽  
Demographic Data ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Antibiotic Use ◽  
Oral Dosage ◽  
Fixed Dose ◽  
Care Hospital ◽  
Prescribing Practices ◽  
Cross Sectional

 Objective: The objective of the study was to evaluate antimicrobial prescription pattern in outpatient departments.Method: This was a prospective, cross-sectional and observational study over 12 weeks total 400 prescriptions of either gender and age; containing antimicrobial agents (AMAs) were analyzed for demographic data and the WHO prescribing indicators.Results: Most of prescription were given to men (n=262). The most common group of AMA used was Cephalosporins (n=141, 35.25%); of which Ceftriaxone was most commonly prescribed (n=73, 18.25%). 10 AMAs were from the WHO essential medicine list AMAs. Men outnumbered women in prescribing antibiotics (n=262 vs. 138). Most of AMAs receivers were between 26 and 35 years (n=128, 32%). Amoxicillin+Clavulanic acid fixed-dose combination was most common (n=84, 21%). Most of the prescriptions were containing four drugs per prescriptions (n=130, 32.5%). Only 10% of the prescription was given by generic name and rest 90% were given by brand name. Oral dosage form of AMAs was predominant (n=340, 85%). Vitamins and supplement were most common comedication received by patients.Conclusion: Antibiotic use was found to be reasonable and rational in most of the cases. However, still, prescribers should improve prescribing practices and make it more rational.

scholarly journals DRUG UTILIZATION STUDY IN OPHTHALMOLOGY OUTPATIENT DEPARTMENT IN A GOVERNMENT TERTIARY CARE HOSPITAL IN MAHARASHTRA

2018 ◽  
Vol 11 (7) ◽  
pp. 167
Author(s):  
Nishandar Tb ◽  
Kale As ◽  
Pise Hn ◽  
Jambhrunkar Sd
Keyword(s):  
Drug Utilization ◽  
Drug Exposure ◽  
Tertiary Care Hospital ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Essential Medicines ◽  
World Health ◽  
Care Hospital ◽  
Age Group

Objective: Drug utilization research is an essential part of pharmacoepidemiology as it describes the extent, nature, and determinants of drug exposure. Indiscriminate use of topical antibiotics, steroids, and nonsteroidal anti-inflammatory drugs causes histological and structural changes in the conjunctiva. The present study was proposed to investigate prescription and drug utilization practices in ophthalmology outpatient department (OPD) in a government tertiary care hospital in Maharashtra.Methodology: An observational, cross-sectional study was conducted in a tertiary care teaching hospital of rural Maharashtra, India, from January 2015 to June 2016 after approval of the institutional ethics committee. Patients of all age group and of either gender attending ophthalmology OPD in a tertiary care hospital were included in the study. Patients not willing to consent as well as follow-up patients were excluded from the study. Data collection was done in a predesigned pro forma. Prescriptions were evaluated for demographic data, World Health Organization (WHO) core drug prescription indicators. Statistical analysis was performed using Microsoft Office Excel® 2007.Results: In a total of 600 patients, females outnumbered males. A bit less than a half of patients belonged to the age group of 19–45 years. An average number of drugs per encounter was (1080/600), i.e. 1.8. Of 1080 total drugs prescribed, 678 drugs (62.78%) were prescribed by their generic name. 1027/1080 (95.09%) drugs were prescribed from the National List of Essential Medicines and 671/1080 (62.13%) drugs prescribed were from the WHO- Essential medicines List. Total encounters having antibiotics and injectable formulations were 274 (45.66%) and 4 (0.66%), respectively.Discussion: Drug utilization studies (DUS) are a tool for assessing the prescribing, dispensing, and distribution of drugs. The main aim of DUS is to facilitate rational use of medicines. Overall findings of the study suggest that ophthalmologists’ drug prescribing habits were appropriate to a larger extent in the current setting.

Drug utilization study in diabetic patients attending medicine outpatient department of a tertiary care hospital

2014 ◽  
Vol 35 (1) ◽  
pp. 8-13
Author(s):  
Satish D. Suthar ◽  
Nirav K. Dholaria ◽  
Dinesh A. Chavda ◽  
Jiyo Chacko ◽  
Nishant B. Bhansali ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Drug Utilization Study

scholarly journals Drug utilization pattern among geriatrics according to anatomical therapeutic chemical and defined daily dose classification in a tertiary care hospital

2019 ◽  
Vol 8 (9) ◽  
pp. 1989
Author(s):  
T. Muneswar Reddy ◽  
Thammi Setty Durga Prasad ◽  
Allikesam Hemalatha ◽  
Vanam Chanukya ◽  
Bandi Lakshmi Sirisha
Keyword(s):  
Drug Utilization ◽  
Anatomical Therapeutic Chemical ◽  
Tertiary Care ◽  
Essential Medicines ◽  
World Health ◽  
Defined Daily Dose ◽  
Care Hospital ◽  
Utilization Pattern ◽  
Geriatric Population ◽  
Daily Dose

Background: This study was conducted to determine the drug utilization pattern among geriatric inpatients in general medicine department of the hospital.Methods: An observational, prospective study was conducted for a period of six months (November 2016 to April 2017) among 200 geriatric patients; demographic details, education, occupation, diagnosis and drug details were recorded. The drugs were categorized by anatomical therapeutic classification (ATC) and defined daily dose (DDD) was calculated. The World Health Organization (WHO) prescribing indicators were assessed.Results: The majority of the patients (59%) were in age group of 60-69 years. Cardiovascular diseases were common among geriatrics. Most commonly prescribed drug was Pantoprazole (81.7%). Drugs were assigned with ATC/DDD codes according to the guidelines of WHO. Drugs prescribed by their generic names were 56.64% and 43% of drugs that were included in the National Essential Medicines List.Conclusions: Clinical pharmacist have to collaborate and work together with physicians in selecting and adjusting the dose among geriatric population in order to reduce development of potential adverse drug reactions, serious drug related complications and drug interaction.

scholarly journals Prescribing pattern of antidiabetic drugs in tertiary care hospital

2021 ◽  
Vol 10 (3) ◽  
pp. 251
Author(s):  
Anil Kumar P. ◽  
Raj Kumar K.
Keyword(s):  
Diabetes Mellitus ◽  
Lifestyle Modification ◽  
Tertiary Care ◽  
Hypoglycemic Agents ◽  
Fixed Dose ◽  
Multiple Drug ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Prescribing Pattern

Background: The aim of the current study was to investigate the prescribing pattern of anti-diabetic drugs in diabetic patients attending tertiary care teaching hospital in Kurnool.Methods: A prospective, cross-sectional, observational survey was carried out in 100 patients of diabetes mellitus attending diabetes outpatient/medicine outpatient departments, to assess their prescribing pattern of anti-diabetic drugs.Results: Average number of anti-diabetic drugs per prescription was 1.4. Metformin (biguanide) was the commonest prescribed individual drug among oral hypoglycemic agents. Fixed dose combination of biguanide and sulfonylurea was prescribed commonly. Monotherapy dominated over polytherapy and there was a higher percentage of use of insulin in type 2 diabetics.Conclusions: OHAs still dominate the prescribing pattern, but there was a shifting trend toward the use of insulin preparations in the management of type 2 diabetes mellitus. Intensification of current drug treatment as well as planning multiple drug interventions with lifestyle modification is necessary.

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