scholarly journals Analysis of prescriptions for completeness in a tertiary care teaching hospital

Author(s):  
Jyothsnya Srinivasa ◽  
Shubhatara Swamy

Background: Prescribing errors are major problems among medication errors. Prescribing errors include mistakes or inaccuracies when choosing and ordering treatments, such as wrong doses or illegible prescriptions. Most of these errors result in no harm or have low to moderate harm however, some result in severe harm or death. There are economic consequences attributed to prescribing errors.Methods: The aim of the study was to analyse the prescriptions for completeness. The prospective observational study was conducted in outpatient department of different specialities in a tertiary care teaching hospital. Prescriptions with atleast one antibiotic, was collected through duplicate copies from the prescribing doctors. The data obtained from prescriptions were analysed and the conclusions were drawn using descriptive analysis.Results: A total of 1516 prescriptions with 3957 drugs were prescribed, out of which 1697 were antibiotics. Average number of drugs per prescription was 2.6 and average number of antibiotics per prescription was 1.1. Patient’s name, age, and gender were mentioned in 99%, 87.8%, and 96% of prescriptions respectively. Generic drug names were used in 0.7% of prescriptions. Out of 1681 antibiotics prescribed in 1574 had appropriate dosage form.Conclusions: The present study highlights the problem of incomplete prescriptions and extensive use of brand names. Intervention strategies focused on education and training, introduction of strict feedback control and monitoring systems are highly effective in reducing prescription errors.

Author(s):  
Vandana Badar ◽  
Vidisha Parulekar ◽  
Priti Garate

Objectives: The objectives of the study were as follows: (1) To study the prescription patterns in Respiratory tract infections (RTI) in indoor patients in pediatric wards. (2) To check the rationality of treatment according to Modified Kunin’s rationality criteria. (3)To analyze the data of RTI by Anatomical Therapeutic Chemical classification.Methods: It was a non-interventional, prospective, observational study which was conducted in indoor pediatric patients in a tertiary care teaching hospital in India. Data were analyzed and evaluated according to the WHO rational use of drugs guidelines.Study sample: The study sample was 174.Study duration: The study duration was August 15, 2016–September 15, 2016.Results: Males (63.79%) were more as compared to females (36.20%), and the highest number of cases was seen in infants (62.06%). Acute bronchiolitis (54.02%) was highest in the incidence followed by Wheeze Associated Lower Respiratory Tract Infection (WALRI) (30.45%). The average duration of patient stay in hospital was 4.71 days whereas 93.33% were polytherapy and mostly prescribed antibiotic was amoxicillin-clavulanic acid in acute bronchiolitis and WALRI. Salbutamol (40.84%) and Ipratropium Bromide (39.43%) were the commonly prescribed respiratory medicines. Oral route (42.27%) was the most common route of administration. 56.11% drugs were prescribed by generic name.Conclusion: Standard treatment guidelines for the treatment of RTI need to be urgently developed and strictly implemented.


Author(s):  
Binu K. M. ◽  
Jenil Johny ◽  
Doddayya Hiremath

Background: The endocrine disorders such as diabetes mellitus, hypothyroidism and hyperthyroidism along with world’s ageing population has increased the burden of health care systems. The present study aimed to assess the prescribing pattern of drugs in endocrine disease like diabetes and thyroid disorder and to evaluate the drug use in given healthcare against programmed criteria and standards.Methods: A prospective observational study was conducted in 220 patients over six months in a tertiary care teaching hospital. Patients who are diagnosed with endocrine disorder in various (general medicine, surgery and Orthopedics) inpatient departments of study hospital.Results: A prospective observational study was carried out by reviewing prescriptions of 220 patients with lifestyle disorders such as, DM (120), hyperthyroidism (50) and hypothyroidism (50). In diabetes, most of the patients were prescribed with biguanides 75 (47.17%) followed by sulfonylureas 56 (35.22%), alpha-glycosidase inhibitors 20 (12.58%), dipeptidyl peptidase 4 inhibitors 5 (3.14%), meglitinides 2 (1.26%) and thiazolidinediones 1 (0.63%). Most of the prescription containing insulin Actrapid and insulin Mixtard 14 (82.35%) followed by insulin Actrapid and insulin NPH 2 (11.76%), insulin Mixtard and insulin Glargine 1 (5.89%). In hypothyroidism most of the patients were prescribed with propylthiouracil 28 (56%) followed by methimazole 26 (44%). Levothyroxine is the best choice of drug for hypothyroid disorder.Conclusions: Our study found that treatment and management of endocrine disorders were not rational. There is a need of clinical pharmacist involvement for a better patient care in these disorders.


Author(s):  
A. R. Malahat ◽  
C. Deepa Latha ◽  
Sudhakar K. ◽  
Deepika Baloju ◽  
G. Vijayalakshmi

Objective: This study attempts to analyze the severe ADRs in a tertiary care centre and assess their seriousness, outcome, causality and severity. We emphasize on the need for reporting of ADRs by all healthcare professionals as it will reduce the burden of morbidity due to drugs and ensure better and more efficient healthcare. To analyse and evaluate the severe ADVERSE DRUG REACTIONs reported from various departments in a Tertiary care Teaching hospital.Methods: It is a prospective observational study that was carried out over a period of 6 mo (from July 2016 to December 2016) to assess the percentage of severe adverse drug reactions reported to the Pharmacovigilance cell of a tertiary care teaching hospital. The data collected included patient’s demographic details, presenting complaints, clinical diagnosis and details of the drug(s) prescribed. The data was analysed for causality (as per the WHO-UMC scale) and severity (as per Hartwig and Siegel scale).Results: Out of 64 ADRs reported, 17 were serious. The majority of serious ADRs were categorized as probable (82.35%), whilst 1(5.8%) was categorized as possible and 2(11.76%) as certain in nature. The criteria for the majority of serious ADRs were hospitalization (%) followed by intervention to prevent permanent impairment or damage (%).Conclusion: The highest percentage of severe cases was reported with Antitubercular therapy (23.5%) followed by analgesics (23%) and anti epileptic agents (17.6%).


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