scholarly journals Meconium stained liquor and perinatal outcome

2018 ◽  
Vol 7 (12) ◽  
pp. 5056
Author(s):  
Aruna Biradar ◽  
Shreedevi Kori ◽  
Neelamma Patil ◽  
S. R. Mudanur
Keyword(s):  
Apgar Score ◽  
Fetal Heart Rate ◽  
Neonatal Intensive Care ◽  
Fetal Heart ◽  
Birth Asphyxia ◽  
Meconium Aspiration Syndrome ◽  
P Value ◽  
Operative Interference ◽  
Nicu Admission ◽  
Meconium Stained Amniotic Fluid

Background: The aim of this study is to know the association between the meconium stained amniotic fluid and its association with the perinatal outcome.Methods: All the patients coming to present hospital for delivery with meconium stained liquor during the study period were included in the study.Results: 163 cases with meconium stained liquor (MSAF) were included in the study, 124(76.1%) and 39(23.9%) had thin and thick MSAF respectively. Among these cases, thick MSAF was more associated with high fetal heart rate (FHR) variability (p value- 0.030), associated with increased rate of operative interference (64.1%; p value- 0.001), abnormal Apgar score (p value-0.003 at 1min and 0.001 at 5min) and increased neonatal intensive care unit (NICU) admission (33.3%; p value - <0.001).Conclusions: Present study showed that thick meconium is associated with more complications like increased operative interference, birth asphyxia, meconium aspiration syndrome, low Apgar score, prolonged NICU stay and overall increased perinatal mortality compared to thin meconium stained liquor. As the gestational age increased the incidence of meconium increased and a greater number of thick meconium had abnormal CTG.

A comparative study on feto-maternal outcome in patients with meconium stained liquor versus clear liquor

2021 ◽  
Vol 10 (11) ◽  
pp. 4119
Author(s):  
Kalpesh Patel ◽  
Radha Rastogi
Keyword(s):  
Amniotic Fluid ◽  
Neonatal Intensive Care ◽  
Fetal Heart ◽  
Acute Hypoxia ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Singleton Pregnancy ◽  
Fetal Movements ◽  
Nicu Admission ◽  
Meconium Stained Amniotic Fluid

Background: Meconium is sterile, thick, black-green, odourless material, formed by accumulation of debris in the fetal intestine. This meconium, when leaks out intra-natally, due to hypoxia, can change the whole scenario, increasing intra-natal foetal risk, morbidity, and possibly causing mortality, depending upon the operative factors. Aims and objectives were to know the perinatal outcome in patients with meconium stained amniotic fluid. To study the complications of meconium stained amniotic fluid in the neonates.Methods: Reverse-transcription polymerase chain reaction (RTPCR) negative women, gestational age >37 weeks with cephalic presentation and singleton pregnancy with meconium stained liquor (grade I, II, and III) after spontaneous or artificial rupture of membranes during labour. Delivery was expedited, when fetal heart rate abnormalities were detected, by safest mode of delivery. The Apgar score of neonates, neonatal intensive care unit (NICU) admission, number of days of hospitalization and birth asphyxia were recorded.Results: A Total 11 patients with pre-eclampsia which presented with meconium stained liquor (MSL). 6 patients with prolonged labour presented with MSL. 8 had thin, 15 had thick MSL and 3 patients of clear liquor. 2 children developed persistent pulmonary hypertension of the newborn (PPHN) in case of MSL group. 25 children required oxygen support and antibiotics after delivery. Mean hospital stay was 2.81 days in MSL and 1.33 days in clear liquor group.Conclusions: Chronic hypoxia is more damaging and dangerous than acute hypoxia, due to longer time it has continued the damage. This can be very effectively achieved by improving the Antenatal care, and intra natal vigilance. Proper monitoring of patients in intrapartum period of following parameters like fetal heart sound, uterine contractions, fetal movements.

scholarly journals Oligohydramnios at third trimester and perinatal outcome

1970 ◽  
Vol 11 (1) ◽  
pp. 33-36 ◽  
Author(s):  
N Nazlima ◽  
B Fatima
Keyword(s):  
Heart Rate ◽  
Apgar Score ◽  
Fetal Heart Rate ◽  
Perinatal Outcome ◽  
Fetal Heart ◽  
P Value ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
Increased Risk ◽  
Nicu Admission

Objectives: The purpose of this study to assess the effect of oligohydramnios on perinatal outcome especially at third trimester of pregnancy. Methods: This prospective and observational study was conducted in a private specialized hospital at Dhaka city from January to December 2009. In this study 78 singleton pregnant females with gestational age from 28 - 42 weeks with less amniotic fluid index (AFI) were analyzed for perinatal outcome. Data were expressed as number (percentage). Proportion test was performed for comparison between two groups , P value <0.05 was taken as level of significance. Results:Women with oligohydramnios were significantly associated with an abnormal antepartum fetal heart rate (FHR), meconium stained fluid, Apgar score less than 7 or NICU admission. Also subjects with AFI of 5.0 cm or less had a higher rate of cesarean section for fetal distress. Conclusions: Antepartum oligohydramnios is associated with an increased risk of fetal heart rate abnormalities. Although in our population it is not predictive of adverse perinatal outcome as measured by low apgar score and NICU admission, yet this may be reflective of the aggressive antepartum and intrapartum management that these patients received. DOI: http://dx.doi.org/10.3329/bjms.v11i1.9820 BJMS 2012; 11(1): 33-36

scholarly journals Study of length of umbilical cord and fetal outcome: a study of 1000 deliveries

2017 ◽  
Vol 6 (9) ◽  
pp. 3770
Author(s):  
Shiva Kumar H. C. ◽  
Chandrashekhar T. Tharihalli ◽  
Chandrashekhar K. ◽  
Suman F. Gaddi
Keyword(s):  
Heart Rate ◽  
Umbilical Cord ◽  
Apgar Score ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Birth Asphyxia ◽  
Fetal Outcome ◽  
The Body ◽  
Operative Interference ◽  
Cord Length

Background: Human embryo develops inside the body of the mother. One of the important part of the fetoplacental unit is the umbilical cord. The umbilical cord is the lifeline of the fetus. Objective of present study was to investigate the correlation of umbilical cord length with fetal parameters like APGAR score, sex, weight, and length, and its effect on labor.Methods: This prospective study conducted in the Department of OBG of VIMS, Bellary, from 1st February 2016 to 31st January 2017. The 1000 pregnant women of >37 weeks were studied following delivery for length of umbilical cord, any loop around neck, trunk, shoulder and number of loops of cord; knots of cord etc. Fetal parameters recorded were sex, weight, and length of the newborn and APGAR score at 1 and 5 min.Results: Cord length varied from 22 to 126 cm. The mean cord length was 66 cm (±10 cm). Maximum cases have cord length of 61and 70 cm. Lower 5th percentile and upper 5th percentile considered as short and long cord. Short-cord group was associated with significantly higher (p<0.05) incidence of LSCS cases. The incidence of all types of cord complications increases as the cord length increases (p<0.001). Nuchal cords had higher mean cord length and as the number of loops in a nuchal cord increases to two or more loops, the operative interference and fetal heart abnormalities increases. Fetal heart rate abnormalities and birth asphyxia increase with extremes of cord length (p<0.001).Conclusions: Short and long cords are associated with increased incidence of cord complications, operative interference, intrapartum complications, increased fetal heart rate abnormalities, and birth asphyxia. But cord length did not vary according to the weight, length, and sex of the baby.

scholarly journals An observational study of meconium aspiration syndrome and its immediate outcome with relation to thick and thin meconium stained amniotic fluid

2018 ◽  
Vol 5 (2) ◽  
pp. 552
Author(s):  
Sushant Kumar ◽  
Minni Rani Akhouri
Keyword(s):  
Amniotic Fluid ◽  
Neonatal Intensive Care ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Meconium Aspiration Syndrome ◽  
P Value ◽  
Meconium Aspiration ◽  
Clinical Criteria ◽  
The Mean ◽  
Meconium Stained Amniotic Fluid

Background: Meconium-stained amniotic fluid (MSAF) accounts for approximately 10-15% of live births and Meconium aspiration syndrome occurs in 5% among infants born through MSAF. The purpose of this study was to evaluate the outcome in neonates with meconium aspiration syndrome with regard to thin and thick meconium. Methods: A prospective cohort study of inborn neonates was done from April 2016 to August 2017 admitted in neonatal intensive care unit, Department of Paediatrics and Neonatology, RIMS, Ranchi after obtaining written informed consent from the parents or guardian and diagnosis of MAS was made depending on the clinical criteria and its clinical outcome was observed. MAS babies were studied on the basis of thin and thick meconium stained amniotic fluid.Results: The mean birth weight in thin meconium was 2760±394. The mean APGAR score in thin meconium at 1 minute (3.57±1.01) and 5 minutes (5.57±1.62) was significantly more than thick meconium. The mode of delivery in thin meconium was commonly by cesarean section (76.9%). There was need for resuscitation in 46.1% in thin meconium neonates which was significantly higher than neonates born with thick meconium 6.6% (P value 0.000). The most common complication in thin meconium was birth asphyxia (69.2%), followed by ARF and septicemia. Death was significantly higher in neonates born with thin meconium (69.2%)as compared to thick (20%) with P value of 0.000Conclusions: Amniotic fluid with thin meconium may cause more respiratory and other complications in neonates than amniotic fluid with thick meconium. Hence proper diagnosis and timely intervention can reduce the morbidity and mortality in neonates with meconium aspiration syndrome.

scholarly journals Fetal heart rate patterns in patients with thick meconium staining of amniotic fluid and its association with perinatal outcome

2017 ◽  
Vol 6 (3) ◽  
pp. 1030 ◽  
Author(s):  
Dharna Desai ◽  
Nandita Maitra ◽  
Purvi Patel
Keyword(s):  
Heart Rate ◽  
Amniotic Fluid ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Caesarean Section Rate ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Neonatal Morbidity ◽  
P Value ◽  
Meconium Staining

Background: This study assesses the role of abnormal fetal heart rate tracing patterns in patients with thick meconium staining of the amniotic fluid and its association with perinatal outcomes.Methods: Prospective unmatched case-control study on 2 groups of 136 subjects each- cases had thick MSAF and controls had clear liquor with abnormal fetal heart rate tracings on cardiotocography.Results: Gestational age (GA) >40 weeks, was found to have a significant association with MSAF (p value 0.01556 CI 95%). Premature Rupture of membranes at term (PROM) showed a significant association with MSAF with an OR of 2.25 (95% CI 1.37, 3.7); Post datism had significantly higher odds for being a risk factor for MSAF with an OR (3.194) (CI 95% 1.003-10.165). MSAF was not found to be significantly associated with abnormal trace on CTG. Neonatal morbidity (MAS, birth asphyxia, sepsis, HIE) had statistically higher odds in cases 1.669 (0.884-3.150) as compared to controls.Conclusions: No particular cardio-tocograph pattern can be considered to have a poor prognostic value in the presence of thick MSAF and the decision to deliver and the mode of delivery should be based on the overall assessment and the stage and progress of labor. While management should be individualized, a higher Caesarean section rate in thick MSAF can be justified to ensure a better outcome for the neonate even in the presence of a normal CTG trace.

scholarly journals Comparative analysis of maternal and fetal outcome in meconium stained amniotic fluid and clear liquor in primigravida

2020 ◽  
Vol 9 (2) ◽  
pp. 482
Author(s):  
Deepali S. Kapote ◽  
Apeksha M. Mohite ◽  
Anam Syed
Keyword(s):  
Heart Rate ◽  
Amniotic Fluid ◽  
Apgar Score ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Birth Asphyxia ◽  
Fetal Outcome ◽  
Control Group ◽  
Singleton Pregnancy ◽  
Meconium Staining

Background: The present study was undertaken to evaluate the significance of MSAF and its fetal outcome in parturients.Methods: A total of 121 pregnant women who had completed more than 37 weeks of gestation with live singleton pregnancy, spontaneous onset of labor and at term with adequate pelvis were included in the study. All (121) low risk primigravida with MSAF were studied to identify maternal and fetal outcome and compared with equal number of cases with clear amniotic fluid. Meconium stained cases were clinically classified into two groups- thin (54 cases) and thick (67 cases). MSAF on spontaneous or artificial rupture of membranes were monitored with fetal heart rate abnormality, 1- and 5-minutes Apgar score, NICU admissions and neonatal complications as outcome variables.Results: Overall incidence of meconium staining of AF during labour was 7.71%. The common fetal heart rate abnormalities i.e. bradycardia was seen in 36% in MSG. Apgar score of less than 7 was observed in MSG at 5 minutes in 5% of cases, in thick group. Major neonatal complication was birth asphyxia in MSG (18.18%) that was more in thick MSG (14.87%). MAS were observed in 6 cases in thick and 4 cases in thin meconium stained cases. NICU care was required in 18% cases in MSG and in control group it was required in 7% cases. Neonatal morbidity was more in newborn with thick meconium group (52%) compared to thin meconium group (20%).Conclusions: The present study confirmed that meconium staining of amniotic fluid adversely influences the fetal outcome.

scholarly journals A prospective clinical study of foetomaternal outcome in relation to oligohydramnios in pregnancies beyond 36 weeks of gestation

2020 ◽  
Vol 9 (6) ◽  
pp. 2342
Author(s):  
B. S. Meena ◽  
Nimisha Gupta ◽  
Oby Nagar ◽  
Swati Trivedi
Keyword(s):  
Respiratory Distress ◽  
Apgar Score ◽  
Neonatal Intensive Care ◽  
Mode Of Delivery ◽  
Meconium Aspiration Syndrome ◽  
Vital Role ◽  
Prospective Clinical Study ◽  
Meconium Aspiration ◽  
Pregnant Females ◽  
Nicu Admission

Background: Amniotic fluid is contributed by both mother and foetus. It plays a vital role in foetal growth. The main purpose of this study was to evaluate the foetomaternal outcome in pregnant females with oligohydramnios beyond 36 weeks of gestation.Methods: This study was conducted on 230 pregnant females beyond 36 weeks of gestation with decreased liquor clinically and confirmed sonographically. It was conducted from May 2018 to May 2019. Females with leaking per vaginum, patients who did not give consent and with intrauterine foetal death were excluded. Complete labour record was made. Assessment of maternal outcome was done in terms of mode of delivery and foetal outcome was done in terms of birth weight, Apgar score at one and five-minute, respiratory distress, meconium aspiration, seizures in first 24 hours of life, congenital malformations, neonatal intensive care unit admission and death of baby.Results: A total of 230 pregnant females met the inclusion criteria who were having AFI <5. 121 (53%) females were primigravida and 119 (52%) underwent for caesarean section. Most common indication of LSCS was foetal distress. Apgar score at 1 minute was <7 in 97 (42%) babies and after 5 minutes, it was <7 in 93 (40%) babies. Other neonatal outcome results were IUGR in 59 (26%) babies, meconium aspiration syndrome in 52 (23%) babies, respiratory distress in 92 (40%) babies, congenital malformation in 6 (3%) babies, NICU admission of 93 (40%) babies and neonatal death of 11 (5%) babies.Conclusions: Oligohydramnios increases the chances of maternal morbidity and perinatal morbidity and mortality.

scholarly journals Influence of foetal inflammation on the development of meconium aspiration syndrome in term neonates with meconium-stained amniotic fluid

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7049 ◽  
Author(s):  
Kyoko Yokoi ◽  
Osuke Iwata ◽  
Satoru Kobayashi ◽  
Kanji Muramatsu ◽  
Haruo Goto
Keyword(s):  
Amniotic Fluid ◽  
Apgar Score ◽  
Neonatal Intensive Care ◽  
Meconium Aspiration Syndrome ◽  
Univariate Logistic Regression Analysis ◽  
Term Neonates ◽  
Meconium Aspiration ◽  
Independent Variable ◽  
Male Sex ◽  
Meconium Stained Amniotic Fluid

Background Meconium-stained amniotic fluid is observed in approximately 10–15% of all deliveries; however, only 5% of neonates with meconium-stained amniotic fluid develop meconium aspiration syndrome (MAS). Although foetal distress and subsequent sympathetic stimulation have been considered as the primary upstream events of MAS, this clinical complication sometimes occurs due to other pathologies, such as intraamniotic inflammation. The aim of this study was to investigate whether the incidence of MAS is associated with the presence of funisitis and chorioamnionitis in term neonates with meconium-stained amniotic fluid. Methods Between April 2013 and March 2015, a total of 95 term neonates with meconium-stained amniotic fluid, who were hospitalized at a neonatal intensive care unit, were enrolled in the study. The placenta and umbilical cord were histopathologically examined. Clinical variables and histopathological findings associated with the incidence of MAS were studied. Results A total of 36 neonates developed MAS. Univariate logistic regression analysis revealed that a heavier birth weight, male sex, 1-min Apgar score ≤ 7, funisitis (but not chorioamnionitis), and elevated acute-phase inflammatory reaction score were associated with increased incidence of MAS (all p < 0.05). The multivariate model comprised funisitis (OR = 5.03, 95% CI [1.63–15.5], 1-min Apgar score ≤ 7 (OR = 2.74, 95% CI [1.06–7.09], and male sex (OR = 3.4, 95% CI [1.24–9.34]. Conclusion In neonates with meconium-stained amniotic fluid, funisitis, as well as low 1-min Apgar score and male sex, was identified as an independent variable for MAS development. Intraamniotic inflammation might be involved in the pathological mechanisms of MAS.

Association of Fetal Heart Rate Baseline Change and Neonatal Outcomes

2017 ◽  
Vol 34 (09) ◽  
pp. 879-886 ◽  
Author(s):  
Molly Stout ◽  
Julia López ◽  
Ryan Colvin ◽  
George Macones ◽  
Alison Cahill ◽  
...  
Keyword(s):  
Heart Rate ◽  
Fetal Heart Rate ◽  
Neonatal Intensive Care ◽  
Fetal Heart ◽  
Fetal Monitoring ◽  
Neonatal Outcomes ◽  
Arterial Ph ◽  
Electronic Fetal Monitoring ◽  
Nicu Admission ◽  
Normal Neonates

Objective The objective of this study was to describe the incidence of baseline change within normal range during labor and its prediction of neonatal outcomes. Materials and Methods This was a prospective cohort of singleton, nonanomalous, term neonates with continuous electronic fetal monitoring and normal baseline fetal heart rate throughout the last 2 hours of labor. We determined baseline in 10-minute segments using Eunice Kennedy Shriver National Institute of Child Health and Human Development criteria. We evaluated baseline changes of ≥ 20 and ≥ 30 bpm for association with acidemia (umbilical cord arterial pH ≤ 7.10) and neonatal intensive care unit (NICU) admission. Finally, we performed a sensitivity analysis of normal neonates, excluding those with acidemia, NICU admission, or 5-minute Apgar < 4. Results Among all neonates (n = 3,021), 1,267 (41.9%) had change ≥ 20 bpm; 272 (9.0%) had ≥ 30 bpm. Among normal neonates (n = 2,939), 1,221 (41.5%) had change ≥20 bpm. Acidemia was not associated with baseline change of any direction or magnitude. NICU admission was associated with decrease ≥ 20 bpm (adjusted odds ratio [aOR]: 2.93; 95% confidence interval [CI]: 1.19 – 7.21) or any direction ≥ 20 bpm (aOR: 4.06; 95% CI: 1.46–11.29). For decrease ≥ 20 bpm, sensitivity and specificity were 40.0 and 81.7%; for any direction ≥ 20 bpm, 75.0 and 58.3%. Conclusion Changes of normal baseline are common in term labor and poorly predict morbidity, regardless of direction or magnitude.

FETOMATERNAL OUTCOME IN MECONIUM STAINED AMNIOTIC FLUID IN A TERTIARY RURAL HEALTH CARE CENTRE

2021 ◽  
pp. 31-33
Author(s):  
Yeshwanthini J ◽  
Mahendra G ◽  
Ravindra S Pukale
Keyword(s):  
Heart Rate ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Birth Asphyxia ◽  
Well Being ◽  
Fetal Outcome ◽  
Meconium Aspiration Syndrome ◽  
Medical Sciences ◽  
Health Care Centre ◽  
Fetal Heart Rate Monitoring

Background: The study was undertaken to determine the correlation of amniotic uid stained with meconium (MSAF) with maternal and fetal outcome. Methods: This prospective observational study was carried out in the Department of Obstetrics and gynecology, Sri Adichunchanagiri Institute of Medical Sciences, BG Nagara for over a period of 6 months between July 2020 and December 2020. A total of 168 pregnant women were included in the study. MSAF on spontaneous or articial rupture of membranes were monitored during labour with fetal heart rate abnormality, consistency of liquor, 1 minute and 5 minute Apgar score, LSCS, instrumental delivery, NICU admissions and neonatal complications as outcome variables. Results: Women were divided into two groups: 69 were cases with meconium stained amniotic uid (MSAF) and 99 were controls with clear amniotic uid. Among 69 cases with MSAF 17.4% were unbooked & 82.6% were booked (at least 3 visits in rst trimester), 79.7% were between 20-30 years of age group. Primigravida's constituted 55.1% in the study group. Approximately 34.8% had gestational ages of >39- 40 weeks. Caesarean section done in cases of MSAF accounted for 55.1% Normal deliveries were 36.2% in cases and 45.5% in controls. Conclusions: Presence of MSAF is worrisome for both the obstetrician and pediatricians view as it increases surgical intervention, birth asphyxia, MAS & NICU admissions. Continuos fetal heart rate monitoring during labour and reassurance of fetal well-being by acid-base assessment were most signicant factors in the reduction of meconium aspiration syndrome

Sign in / Sign up

Export Citation Format

Share Document