A comparative study on feto-maternal outcome in patients with meconium stained liquor versus clear liquor

2021 ◽  
Vol 10 (11) ◽  
pp. 4119
Author(s):  
Kalpesh Patel ◽  
Radha Rastogi
Keyword(s):  
Amniotic Fluid ◽  
Neonatal Intensive Care ◽  
Fetal Heart ◽  
Acute Hypoxia ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Singleton Pregnancy ◽  
Fetal Movements ◽  
Nicu Admission ◽  
Meconium Stained Amniotic Fluid

Background: Meconium is sterile, thick, black-green, odourless material, formed by accumulation of debris in the fetal intestine. This meconium, when leaks out intra-natally, due to hypoxia, can change the whole scenario, increasing intra-natal foetal risk, morbidity, and possibly causing mortality, depending upon the operative factors. Aims and objectives were to know the perinatal outcome in patients with meconium stained amniotic fluid. To study the complications of meconium stained amniotic fluid in the neonates.Methods: Reverse-transcription polymerase chain reaction (RTPCR) negative women, gestational age >37 weeks with cephalic presentation and singleton pregnancy with meconium stained liquor (grade I, II, and III) after spontaneous or artificial rupture of membranes during labour. Delivery was expedited, when fetal heart rate abnormalities were detected, by safest mode of delivery. The Apgar score of neonates, neonatal intensive care unit (NICU) admission, number of days of hospitalization and birth asphyxia were recorded.Results: A Total 11 patients with pre-eclampsia which presented with meconium stained liquor (MSL). 6 patients with prolonged labour presented with MSL. 8 had thin, 15 had thick MSL and 3 patients of clear liquor. 2 children developed persistent pulmonary hypertension of the newborn (PPHN) in case of MSL group. 25 children required oxygen support and antibiotics after delivery. Mean hospital stay was 2.81 days in MSL and 1.33 days in clear liquor group.Conclusions: Chronic hypoxia is more damaging and dangerous than acute hypoxia, due to longer time it has continued the damage. This can be very effectively achieved by improving the Antenatal care, and intra natal vigilance. Proper monitoring of patients in intrapartum period of following parameters like fetal heart sound, uterine contractions, fetal movements.

scholarly journals Meconium stained liquor and perinatal outcome

2018 ◽  
Vol 7 (12) ◽  
pp. 5056
Author(s):  
Aruna Biradar ◽  
Shreedevi Kori ◽  
Neelamma Patil ◽  
S. R. Mudanur
Keyword(s):  
Apgar Score ◽  
Fetal Heart Rate ◽  
Neonatal Intensive Care ◽  
Fetal Heart ◽  
Birth Asphyxia ◽  
Meconium Aspiration Syndrome ◽  
P Value ◽  
Operative Interference ◽  
Nicu Admission ◽  
Meconium Stained Amniotic Fluid

Background: The aim of this study is to know the association between the meconium stained amniotic fluid and its association with the perinatal outcome.Methods: All the patients coming to present hospital for delivery with meconium stained liquor during the study period were included in the study.Results: 163 cases with meconium stained liquor (MSAF) were included in the study, 124(76.1%) and 39(23.9%) had thin and thick MSAF respectively. Among these cases, thick MSAF was more associated with high fetal heart rate (FHR) variability (p value- 0.030), associated with increased rate of operative interference (64.1%; p value- 0.001), abnormal Apgar score (p value-0.003 at 1min and 0.001 at 5min) and increased neonatal intensive care unit (NICU) admission (33.3%; p value - <0.001).Conclusions: Present study showed that thick meconium is associated with more complications like increased operative interference, birth asphyxia, meconium aspiration syndrome, low Apgar score, prolonged NICU stay and overall increased perinatal mortality compared to thin meconium stained liquor. As the gestational age increased the incidence of meconium increased and a greater number of thick meconium had abnormal CTG.

scholarly journals The study of meconium staining of amniotic fluid and foetal outcome

2018 ◽  
Vol 7 (10) ◽  
pp. 4042 ◽  
Author(s):  
Bhagyashri Gavhane ◽  
Sarika Thakare ◽  
Sachin Wankhede
Keyword(s):  
Amniotic Fluid ◽  
Perinatal Mortality ◽  
Prospective Observational Study ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Singleton Pregnancy ◽  
Foetal Outcome ◽  
The Mean ◽  
Meconium Staining ◽  
Meconium Stained Amniotic Fluid

Background: This study was carried out to determine the effect of meconium stained amniotic fluid on mode of delivery and correlation of thick and thin meconium with foetal outcome.Methods: This prospective observational study was carried out in the Department of obstetrics and gynecology, IGGMC Nagpur from September 2015 to August 2017. All pregnant women in labor with cephalic presentation with singleton pregnancy with meconium stained liquor irrespective of age, parity and stage of labor were enrolled in this study. 200 consecutive study subjects who fulfilled inclusion criteria were included in the study.Results: Out of 200 cases of MSAF, thick meconium was seen in 53.5% cases and thin meconium constituted 46.5% of the cases. The mean gestational age in present study was 39.31 ± 0.89 weeks. Overall incidence of LSCS in meconium stained amniotic fluid is 65.5%. The thick Meconium stained grades had significantly higher NICU admissions when compared to the thin meconium grades (p<0.05). In present study, the total perinatal mortality was 4%.Conclusions: MSAF were associated with higher rate of caesarean delivery. It causes birth asphyxia, MAS, increases NICU admissions and perinatal mortality.

scholarly journals An observational study of meconium aspiration syndrome and its immediate outcome with relation to thick and thin meconium stained amniotic fluid

2018 ◽  
Vol 5 (2) ◽  
pp. 552
Author(s):  
Sushant Kumar ◽  
Minni Rani Akhouri
Keyword(s):  
Amniotic Fluid ◽  
Neonatal Intensive Care ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Meconium Aspiration Syndrome ◽  
P Value ◽  
Meconium Aspiration ◽  
Clinical Criteria ◽  
The Mean ◽  
Meconium Stained Amniotic Fluid

Background: Meconium-stained amniotic fluid (MSAF) accounts for approximately 10-15% of live births and Meconium aspiration syndrome occurs in 5% among infants born through MSAF. The purpose of this study was to evaluate the outcome in neonates with meconium aspiration syndrome with regard to thin and thick meconium. Methods: A prospective cohort study of inborn neonates was done from April 2016 to August 2017 admitted in neonatal intensive care unit, Department of Paediatrics and Neonatology, RIMS, Ranchi after obtaining written informed consent from the parents or guardian and diagnosis of MAS was made depending on the clinical criteria and its clinical outcome was observed. MAS babies were studied on the basis of thin and thick meconium stained amniotic fluid.Results: The mean birth weight in thin meconium was 2760±394. The mean APGAR score in thin meconium at 1 minute (3.57±1.01) and 5 minutes (5.57±1.62) was significantly more than thick meconium. The mode of delivery in thin meconium was commonly by cesarean section (76.9%). There was need for resuscitation in 46.1% in thin meconium neonates which was significantly higher than neonates born with thick meconium 6.6% (P value 0.000). The most common complication in thin meconium was birth asphyxia (69.2%), followed by ARF and septicemia. Death was significantly higher in neonates born with thin meconium (69.2%)as compared to thick (20%) with P value of 0.000Conclusions: Amniotic fluid with thin meconium may cause more respiratory and other complications in neonates than amniotic fluid with thick meconium. Hence proper diagnosis and timely intervention can reduce the morbidity and mortality in neonates with meconium aspiration syndrome.

scholarly journals Perinatal outcome in meconium-stained amniotic fluid at term: a single center prospective study

2020 ◽  
Vol 10 (1) ◽  
pp. 107
Author(s):  
Vandana Mohapatra ◽  
Sujata Misra ◽  
Tapas Ranjan Behera
Keyword(s):  
Caesarean Section ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Perinatal Outcome ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Control Group ◽  
Study Group ◽  
The Mean ◽  
Meconium Stained Amniotic Fluid

Background: The presence of meconium-stained amniotic fluid is a sign of fetal compromise and is associated with increased perinatal morbidity. The objective of this study was to determine the perinatal outcome in pregnant women at term with meconium-stained amniotic fluid (MSAF) and compare it with the outcome associated with clear liquor. Methods: A prospective observational, study was conducted in the department of obstetrics and gynecology, VIMSAR, Burla from January, 2013 to June, 2013. Pregnant women with singleton pregnancy, cephalic presentation at term were included in the study. Total 135 cases of MSAF (study group) were compared with 165 randomly selected controls with clear liquor. Outcome measures were fetal heart rate (FHR) abnormality, mode of delivery, Apgar score, neonatal intensive care unit (NICU) admission, diagnosis of meconium aspiration syndrome (MAS), birth asphyxia and neonatal death. Statistical analysis was done by using the mean and Chi-square test with or without Yates’ correction.  Results: The mean gestational age for meconium staining in the present study was 40.31±0.48 weeks. Caesarean section was the most common mode of delivery in MSAF group whereas vaginal delivery was most common in control group. Significantly higher number of babies in the study group required NICU admissions. The incidence of MAS and birth asphyxia too was statistically higher among babies born to study group as compared to control group.Conclusions: MSAF has significant adverse effect on the perinatal outcome, as it increases the caesarean section rates, NICU admissions, MAS and birth asphyxia.

scholarly journals Study on Meconium stained fluid-perinatal outcome

2018 ◽  
Vol 7 (2) ◽  
pp. 587
Author(s):  
Soumya Harikumar ◽  
Aparna Rajesh
Keyword(s):  
Amniotic Fluid ◽  
Fetal Heart ◽  
Mode Of Delivery ◽  
Perinatal Outcomes ◽  
Perinatal Morbidity ◽  
Neonatal Complications ◽  
Heart Monitoring ◽  
Admission Test ◽  
Meconium Stained Amniotic Fluid ◽  
Very High

Background: The objective of this study is to find a correlation between the presence of MSAF in mothers with co- morbidities like PIH and GDM and to study the fetal heart variability in cases with MSAF and the significance of an admission test. This study also throws a light on the perinatal outcomes associated with MSAF.Methods: 100 women in labor with Meconium stained amniotic fluid were taken in this study. An admission test was done for all patients, along with continuous fetal heart monitoring was done in the presence of MSAF. Effect of thin and thick meconium on fetus was studied. The cases with maternal co-morbidities were closely monitored along with the mode of delivery, Apgar score, birth weight, resuscitation of baby was studied. All the newborns born through meconium stained liquor were followed up to one week of neonatal life.Results: Out of a total of 100 cases there was 60 cases with thick meconium with a non-reactive NST seen in 65% cases with thick MSAF and 32.5% cases with thin MSAF. 79% of cases with MSAF underwent emergency LSCS. The neonatal complications were more with thick meconium stained liquor accounting to 28.3% incidence of MAS, 23.3% of sepsis, 3.3%of pneumonitis and 21.7% of birth asphyxia.Conclusions: This study ascertained the need for an admission test and continuous CTG monitoring in cases detected to have meconium stained amniotic fluid. Co-morbidities like GDM did have a small role to play though the incidence was not very high. The neonatal complications were more common among cases with thick meconium stained liquor and probably the use of procedures like amnioinfusion can bring down the incidence of perinatal morbidity along with the rate of caesarean sections.

scholarly journals Fetal heart rate patterns in patients with thick meconium staining of amniotic fluid and its association with perinatal outcome

2017 ◽  
Vol 6 (3) ◽  
pp. 1030 ◽  
Author(s):  
Dharna Desai ◽  
Nandita Maitra ◽  
Purvi Patel
Keyword(s):  
Heart Rate ◽  
Amniotic Fluid ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Caesarean Section Rate ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Neonatal Morbidity ◽  
P Value ◽  
Meconium Staining

Background: This study assesses the role of abnormal fetal heart rate tracing patterns in patients with thick meconium staining of the amniotic fluid and its association with perinatal outcomes.Methods: Prospective unmatched case-control study on 2 groups of 136 subjects each- cases had thick MSAF and controls had clear liquor with abnormal fetal heart rate tracings on cardiotocography.Results: Gestational age (GA) >40 weeks, was found to have a significant association with MSAF (p value 0.01556 CI 95%). Premature Rupture of membranes at term (PROM) showed a significant association with MSAF with an OR of 2.25 (95% CI 1.37, 3.7); Post datism had significantly higher odds for being a risk factor for MSAF with an OR (3.194) (CI 95% 1.003-10.165). MSAF was not found to be significantly associated with abnormal trace on CTG. Neonatal morbidity (MAS, birth asphyxia, sepsis, HIE) had statistically higher odds in cases 1.669 (0.884-3.150) as compared to controls.Conclusions: No particular cardio-tocograph pattern can be considered to have a poor prognostic value in the presence of thick MSAF and the decision to deliver and the mode of delivery should be based on the overall assessment and the stage and progress of labor. While management should be individualized, a higher Caesarean section rate in thick MSAF can be justified to ensure a better outcome for the neonate even in the presence of a normal CTG trace.

scholarly journals Comparative analysis of maternal and fetal outcome in meconium stained amniotic fluid and clear liquor in primigravida

2020 ◽  
Vol 9 (2) ◽  
pp. 482
Author(s):  
Deepali S. Kapote ◽  
Apeksha M. Mohite ◽  
Anam Syed
Keyword(s):  
Heart Rate ◽  
Amniotic Fluid ◽  
Apgar Score ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Birth Asphyxia ◽  
Fetal Outcome ◽  
Control Group ◽  
Singleton Pregnancy ◽  
Meconium Staining

Background: The present study was undertaken to evaluate the significance of MSAF and its fetal outcome in parturients.Methods: A total of 121 pregnant women who had completed more than 37 weeks of gestation with live singleton pregnancy, spontaneous onset of labor and at term with adequate pelvis were included in the study. All (121) low risk primigravida with MSAF were studied to identify maternal and fetal outcome and compared with equal number of cases with clear amniotic fluid. Meconium stained cases were clinically classified into two groups- thin (54 cases) and thick (67 cases). MSAF on spontaneous or artificial rupture of membranes were monitored with fetal heart rate abnormality, 1- and 5-minutes Apgar score, NICU admissions and neonatal complications as outcome variables.Results: Overall incidence of meconium staining of AF during labour was 7.71%. The common fetal heart rate abnormalities i.e. bradycardia was seen in 36% in MSG. Apgar score of less than 7 was observed in MSG at 5 minutes in 5% of cases, in thick group. Major neonatal complication was birth asphyxia in MSG (18.18%) that was more in thick MSG (14.87%). MAS were observed in 6 cases in thick and 4 cases in thin meconium stained cases. NICU care was required in 18% cases in MSG and in control group it was required in 7% cases. Neonatal morbidity was more in newborn with thick meconium group (52%) compared to thin meconium group (20%).Conclusions: The present study confirmed that meconium staining of amniotic fluid adversely influences the fetal outcome.

scholarly journals Clinical study of babies born through meconium stained amniotic fluid

2019 ◽  
Vol 6 (2) ◽  
pp. 491 ◽  
Author(s):  
Shilpasri Y. M. ◽  
Madhurya B.
Keyword(s):  
Amniotic Fluid ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Fetal Monitoring ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration ◽  
Medical College ◽  
Meconium Stained Amniotic Fluid

Background: Meconium stained amniotic fluid has been considered a sign of fetal distress and associated with poor fetal outcome, but others considered meconium passage by fetus is physiological phenomena and produce environmental hazards to fetus before birth. Such magnitude of different opinion was the object behind taking up of this study and aim was to find out incidence and effect of meconium in terms of morbidity and mortality.Methods: Two hundred babies born with meconium stained amniotic fluid considering the inclusion and exclusion criteria from December 2012 to June 2013 in the Department of Paediatrics, Cheluvamba hospital attached to Mysore Medical College and Research Institute, Mysore. Fetal monitoring, mode of delivery, Apgar score, birth weight, resuscitation of baby are noted. All babies followed-up up to 1st week of neonatal life.Results: In present study 200 babies born through meconium stained amniotic fluid was randomly selected-thin 37% and thick 63%. Major complications like birth asphyxia, meconium aspiration syndrome, early neonatal death seen in 5.5% (11 cases), morbidity in 37%, 12.5% in thin and 24.5% in thick MSAF. Causes of death were meconium aspiration syndrome in 3 cases, sepsis in 1 case, pneumonia in 1 case and birth asphyxia in 6 cases.Conclusions: Immediate airway management, need for suction and intubation should be guided by state of newborn rather than presence of meconium. Timely diagnosis and management of meconium stained amniotic fluid may improve fetal outcome. From present study authors conclude that MSAF adversely affect fetal outcome mostly by thick meconium.

scholarly journals Meconium-stained amniotic fluid as a risk factor for perinatal asphyxia

2019 ◽  
Vol 6 (2) ◽  
pp. 325
Author(s):  
Vidhi Mehta ◽  
Adarsh E. ◽  
Spoorthi . ◽  
Archana . ◽  
Muhammed Hassan
Keyword(s):  
Amniotic Fluid ◽  
Medical Records ◽  
Neonatal Intensive Care ◽  
Perinatal Asphyxia ◽  
Mode Of Delivery ◽  
Fetal Outcome ◽  
Meconium Aspiration Syndrome ◽  
Efficient Delivery ◽  
Meconium Stained Amniotic Fluid ◽  
Delivery Room Management

Background: The aim of this study was to find out immediate fetal outcome in meconium-stained amniotic fluid in relation to perinatal asphyxia.Methods: This retrospective study includes medical records of all neonates admitted to Neonatal Intensive Care Unit (NICU) between December 2016 and July 2018. The variables reviewed are age, sex, weight, mode of delivery, gestational age, presence of meconium aspiration syndrome (MAS) and perinatal asphyxia.Results: Out of 408 total admissions in NICU, 69.1% were male babies and remaining 30.9% were female babies. In the study out of 36 subjects with Perinatal Asphyxia, 38.9% had MAS and 61.1% had not MAS. Out of 372 subjects without perinatal asphyxia, 93.8% had no MAS and 6.2% had MAS. There was significant association between MAS and perinatal asphyxia. Odds ratio was 9.656. i.e. those with MAS had 9.656 times higher risk for perinatal asphyxia.Conclusions: The management of MAS, which is a perinatal problem, requires a well concerted and coordinated action by the obstetrician and pediatrician. Prompt and efficient delivery room management can minimize the sequelae of aspirated meconium and decrease the chance of perinatal asphyxia in the new born babies.

scholarly journals MECONIUM STAINED AMNIOTIC FLUID AND ITS NEONATAL OUTCOME IN A RURAL TERTIARY CARE CENTER NEAR MATHURA

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Nitin Gyaras Puria ◽  
Krishna Pada Dutta
Keyword(s):  
Amniotic Fluid ◽  
Neonatal Outcome ◽  
Care Center ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Neonatal Morbidity ◽  
Meconium Aspiration Syndrome ◽  
Morbidity And Mortality ◽  
Nicu Admission ◽  
Meconium Stained Amniotic Fluid

The presence of meconium stained amniotic fluid (MSAF) is a sign of fetal compromise. It is associated with significant neonatal morbidity and mortality. MSAF is frequently associated with high cesarean rate, prolonged labour,low APGAR scores, increased rate of birth asphyxia; increased NICU admission, meconium aspiration syndrome and neonatal death. The aim of this prospective study is to correlate the effect of meconium stained amniotic fluid on neonatal outcome. Keywords: Meconium stained amniotic fluid, Neonatal morbidity and mortality, NICU.

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