scholarly journals Efficacy of intracuff dexamethasone in reducing the incidence of post-operative sore throat: an original article

Author(s):  
Reshma Sugathan ◽  
Sumesh Raj

Background: Postoperative sore throat is the most common and most distressing complaint of patients after general anaesthesia with cuffed endotracheal tube. By this study our aim was to assess the efficacy of intracuff dexamethasone in reducing the incidence of this distressing postoperative symptom.Methods: Patients were divided into two groups D and N depending on cuff filling with dexamethasone and normal saline respectively. The cuff was prefilled with dexamethasone or normal saline  one hour prior to intubation to allow time for cuff to be saturated following which the cuff was deflated. General anaesthesia was administered and patients were intubated, and cuff inflated with drug according to group allocated. Patients were assessed and graded for sore throat using VAS scale both at rest and with swallowing. Assessment was done one hour, six, 12 and 24hours post operatively. Presence of hoarseness of voice and cough was assessed on a 2-point scale 0=absent and 1=present, 24hrs after surgery.Results: The incidence of sore throat at 24hours postoperative was reduced in group D than in group N. 4 patients (8%) in group D had sore throat while 27 patients (57%) in group N had sore throat at 24hours. This was statistically significant (p<0.05). The cough incidence was reduced in group D while there was no difference in incidence of hoarseness of voice between the two groups.Conclusions: Intracuff dexamethasone decreases the incidence of postoperative sore throat when compared to intracuff normal saline. Dexamethasone also reduces postoperative cough incidence but does not reduce the incidence of hoarseness of voice.

Author(s):  
Anjali Modak ◽  
Eshana Rasheed ◽  
Nikhil Bhalerao ◽  
Pallavi Devulkar

Background & Objective: In the post operative period, Sore throat is a common morbidity following tracheal intubation. The aim was to compare ketamine nebulisation with ketamine gargle to see the effectiveness of nebulisation over gargle in reducing the incidence and severity of post operative sore throat (POST). Methods: In this prospective, randomized study 80 patients between 18-64 year, of either sex belonging to ASA I/II, scheduled for elective surgery under general anaesthesia, were assigned into two groups of 40 patients each. Group GK received preservative free ketamine 50mg in 29 ml of saline, gargled for 30 seconds and Group NK received ketamine 50 mg in 4ml of normal saline via nebulisation for 15 min. General anaesthesia was induced 5 min later in both the groups. Postoperatively sore throat was assessed at 0, 2, 4, 24 hrs using four point scale (0-3). Results: The incidence of POST at 0, 2, 4, 24 hrs was 27%, 25%, 20% and 17% respectively in GK group and 20%, 17.5%, 12.5% and 7.5% in NK group respectively with no statistical difference between the two.. None of the patients in either group experienced severe sore throat. Conclusion: Ketamine nebulisation seemed to represent an effective alternative to ketamine gargle for reliving Post Operative sore throat.


2018 ◽  
Vol 6 (2) ◽  
pp. 73-77 ◽  
Author(s):  
Muhammad Sazzad Hossain ◽  
Mamunur Rashid ◽  
Anisur Rahman Babu ◽  
Devashis Saha ◽  
Debasish Banik

Background: Postoperative sore throat (POST) though a minor sequel after general anaesthesia with endotracheal intubation, it can be distressing to the patient.Objective: The effectiveness of lubricating endotracheal tube with 0.05% betamethasone gel or intravenous dexamethasone in reducing the postoperative sore throat was compared.Materials and method: This was a prospective study carried out among ninety ASA I and II informed consenting patients aged 20-50 years undergoing elective surgery under general anaesthesia with endotracheal intubation. The patients were randomly divided into three groups with thirty subjects in each group. Betamethasone gel (0.05%) was applied over endotracheal tube over 15 cm mark from the tip in group I, intravenous dexamethasone was given in group II and group III was taken as control. In post-anaesthesia care unit, an anesthesiologist interviewed all patients on postoperative sore throat at 1 hour, 6 hours and 24 hours after operation.Results: At 24 hours following extubation, there was statistically significant lower incidence of post-operative sore throat (POST) in betamethasone group compared to other two groups (betamethasone group 3.33%, dexamethasone group 20% and control group 26.66%, p<0.05). When the groups were compared in pairs at 24 hours, there was statistically significant difference in the incidence of POST between betamethasone group and dexamethasone group and also betamethasone group and control group with lower incidence of POST in betamethasone group, p<0.05. It was also observed that there was no significant difference of POST between dexamethasone and control group at 1 hour, 6 hours or 24 hours, p>0.05.Conclusion: It can be concluded that the use of 0.05% betamethasone gel to lubricate widely the endotracheal tube prior to intubation effectively reduces postoperative sore throat, compared to intravenous dexamethasone administration.Delta Med Col J. Jan 2018 6(2): 73-77


2021 ◽  
pp. 15-16
Author(s):  
Stalin Ramamoorthy ◽  
Muthukumar Thangaraj

Background and Objectives: Controlled comparison between 0.05% betamethasone gel, 2% lidocaine jelly, lubricating gel applied over endotracheal tube to reduce postoperative sore throat, cough, and hoarseness of voice at 0,6,&24 hrs Materials And Methods: This study compares the incidence of postoperative sore throat, cough, and hoarseness ovoice after general anaesthesia when applying betamethasone gel (betamethasone group-B) or lidocaine jelly( lidocaine group -L) on the tracheal tube. 120 ASAclass I and II patients undergoing elective surgeries under general anaesthesia with orotracheal intubation were randomized into three groups: betamethasone gel, lidocaine jelly, and control groups (C group). In the post-anaesthesia care unit, all patients were interviewed on postoperative sore throat, cough, and hoarseness of voice at 0, 6, and 24 h after surgery. Results and Conclusion:Awide spread application of betamethasone gel (B) on the endotracheal tube decreases the incidence and severity of postoperative sore throat, cough, and hoarseness of voice as compared to lignocaine group(L) and control group (c).


1997 ◽  
Vol 32 (4) ◽  
pp. 533
Author(s):  
Tae Gan Ryu ◽  
Jong Sul Kim ◽  
Young Cheol Park ◽  
Suk Min Yoon ◽  
Young Seok Choi ◽  
...  

1970 ◽  
Vol 5 (1) ◽  
pp. 25-28
Author(s):  
Nadeem Parvez Ali ◽  
Md Tauhid-ul-Mulck ◽  
Mahbub Noor ◽  
Md Torab Mollick ◽  
Masud Ahmed ◽  
...  

A prospective study was carried on 120 patients undergoing surgical operations lasting less than 90 minutes. The incidence of postoperative sore throat, dysphasia and hoarseness of voice with 2% lidocaine (Group L) as endotracheal cuff inflating agent was compared with that with distilled water (Group D) and air (Group A). Seventy two percent of lidocaine group in comparison to 60% distilled water group and 37% air group experienced none of the above complications during the entire study period. Only 5% in lidocaine group had sore throat after 22-24 hours compared to 20% in the distilled water group and 45% in the air group. Twenty three percent complained of dysphasia in both lidocaine and distilled water group after 1-3 hours compared to 45% in air group. After 22-24 hours it completely resolved in lidocaine group compared to 20% persisting in the other two groups. Twenty three percent complained of hoarseness in lidocaine group as compared to 35% and 55% in distilled water and air groups respectively after 1-3 hours. This completely resolved in lidocaine group but persisted in 20% and 45% in the distilled water and air group respectively after 22-24 hours. The results showed an advantage in using lidocaine as an endotracheal tube cuff inflating agent in reducing postoperative sore throat, dysphasia and hoarseness in comparison to distilled water and air. Key Words: Lidocain, Endotracheal tube (ETT) cuff inflating agent.   doi: 10.3329/jafmc.v5i1.2847 JAFMC Bangladesh. Vol 5, No 1 (June) 2009 pp.25-28


2018 ◽  
Vol 5 (1) ◽  
pp. 10-15 ◽  
Author(s):  
Sujita Manandhar ◽  
Kishor Manandhar ◽  
Sharad Khakrel

Introductions: Postoperative sore throat (POST) is a commonly seen adverse event after general anesthesia with endotracheal intubation. Dexamethasone, a potent corticosteroid with anti-inflammatory action is the most popular steroid studied in this regard with positive results. Methods: This randomized, prospective, double-blinded, placebo-controlled study was conducted on one hundred and ten adult patients of either sex, American Society of Anesthesiologists physical status I & II, undergoing elective surgeries requiring endotracheal tube intubation. After obtaining written informed consent, they were randomly divided into Control (A, n=55) and Dexamethasone (B, n=55) groups and received either an injection of Dexamethasone (Group B) 8 mg intravenously or an equivalent volume of Normal Saline (Group A) just before entering the operating theatre. All the patients received a similar anesthesia with endotracheal tube intubation and at the end of surgery, extubated and transferred to the post-anesthesia care unit. The incidence and severity of sore throat were assessed at 1, 6 and 24 hours post-extubation. Severity of sore throat were graded on a 4 point scale, p <0.05 was considered significant. Results: Incidence of POST in Dexamethasone group was found significantly low compared to the control group up to six hours (p<0.05) but was comparable at 24 hours post extubation. Severity of POST in the study group was of lower grade in compare to control group. Conclusions: Prophylactic intravenous Dexamethasone 8 mg administered to patients undergoing elective surgeries requiring endotracheal tube intubation significantly reduces the incidence and severity of POST up to six hours post-extubation.


Sign in / Sign up

Export Citation Format

Share Document