scholarly journals Helicobacter pylori infection among type 2 diabetics: a case control study

2020 ◽  
Vol 8 (3) ◽  
pp. 1047
Author(s):  
Hafiz Qazi Muhammad Amir ◽  
Omaila Ikram ◽  
Muhammad Tayyab Zia ◽  
Fareha Kashan Theba ◽  
Naila Ikram ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Case Control Study ◽  
Case Control ◽  
Helicobacter Pylori Infection ◽  
P Value ◽  
Type 2 Diabetics ◽  
Dyspeptic Symptoms ◽  
H Pylori ◽  
Control Study

Background: Helicobacter pylori infection has been associated with hyperglycemia among type 2 diabetics. The objective of this study was to compare the H. pylori infection frequency in diabetic and non-diabetic patients.Methods: This case-control study was done at Al-Tibri Medical College and Hospital from May 2019 to August 2019. After written and informed consent, patients between 18-75 years with epigastric burning, dyspepsia, regurgitation were included and with history of eradication therapy, antibiotic or NSAID use in the last 6 months or surgery of upper GI tract months were excluded. Type 2 diabetics were placed in one group and non-diabetic individuals in another. Both groups were compared for presence of H. pylori infection. Data was analysed using SPSS. Demographic variables included age, gender and status of H. pylori infection. Quantitative data was expressed as frequency and percentages. Chi-square test was applied to test for significance keeping p-value of <0.05 statistically significant.Results: From 480 patients, 355 patients showed positive H. pylori, among them 282 were diabetic and 73 non-diabetic (p-value <0.001). Amongst the 355 diabetics, 55% were male Among 73 non-diabetics, 64% were male. All the patients in the study had dyspeptic symptoms and complained of dyspepsia, epigastric burning and regurgitation.Conclusions: A substantial relationship between H. pylori infection among type 2 diabetes mellitus patients was observed compared to non-diabetics. As a result, diabetic patients having active dyspeptic symptoms should undergo further confirmatory tests for diagnosing H. pylori infection.

scholarly journals Helicobacter pylori risk in type 2 diabetes mellitus: a hospital based case-control study

2017 ◽  
Vol 4 (10) ◽  
pp. 3419 ◽  
Author(s):  
Rajesh S. ◽  
Reshma S. ◽  
Shruthi Kamal V.
Keyword(s):  
Helicobacter Pylori ◽  
Case Control Study ◽  
Case Control ◽  
Diabetic Patients ◽  
Type Ii ◽  
Dyspeptic Symptoms ◽  
H Pylori ◽  
Type 2 Diabetic ◽  
Control Study

Background: The aim of this study is to determine the frequency of Helicobacter pylori (H. pylori) infection in Type 2 diabetic and non-diabetic patients with dyspeptic symptoms and to compare the frequency of H. pylori infection in both groups.Methods: This was a hospital-based case-control study was conducted on 196 subjects in the Department of General Surgery, Saveetha Medical College and Hospital (tertiary care hospital) from March 2016 to November 2016. Patients were divided into two groups i.e. type 2 diabetics with poor glycemic control with dyspeptic symptoms and non-diabetics with dyspeptic symptoms. Each group consisted of 98 patients. All type 2 diabetic patients of ≥35 years of age with poor glycemic control both gender and the known cases with history of dyspepsia, epigastric pain or bloating for more than a month were screened for helicobacter pylori infection. The collected data of both groups was evaluated and separated for analysisResults: Majority of the patients were male with mean age±SD, 50±12. Among the type II diabetic group with dyspeptic symptoms, H. pylori was positive in 70/98 (71.4%), whereas in non-diabetic group with dyspeptic symptoms H. pylori was positive in 51/98 (52%) cases.Conclusion: Type II diabetic patients with dyspeptic symptoms are more prone and at risk to acquire H. pylori infection. Therefore, proper monitoring of blood glucose level and screening for H. pylori infection are effective preventive measures for this chronic infection. 

scholarly journals COBALAMIN DEFICIENCY

2016 ◽  
Vol 23 (02) ◽  
pp. 176-181
Author(s):  
Shumaila Shaikh ◽  
Azhar Memon ◽  
Muhammad Atif Ata ◽  
Haji Khan Khoharo
Keyword(s):  
Helicobacter Pylori ◽  
Case Control Study ◽  
Case Control ◽  
University Hospital ◽  
Cobalamin Deficiency ◽  
P Value ◽  
Significant Difference ◽  
Design Case ◽  
H Pylori ◽  
Control Study

Objectives: The present study aims to evaluate the serum cobalamin inHelicobacter pylori (H. pylori) infected patients. Study Design: Case control study. Place andDuration: Department of Medicine, Isra University Hospital Hyderabad from March 2013- April2014. Methodology: A sample of 109 subjects including Helicobacter pylori positive subjectsand controls were selected according to study criteria. Centrifugation of blood was performedat 4000 rpm for 10 minutes and sera were stored at -20oC. Blood sera were used for H. pyloriserological testing. Blood counting was performed on hematoanalyzer. Cobas e411 analyzerwas used for detection of cobalamin. 64 kD H. pylori antigens was detected by ELISA. Thedata was entered into SPSS version 21.0. (IBM, Incorporation, USA) A 2-tailed p-value of ≤0.05was considered significant for statistical analysis. Results: Of total 109, 54.1% (n=59) wereH. pylori seropositive cases and others were controls i.e. 45.9% (n=50). Cases and controlsshowed cobalamin levels of 290±49.3 vs. 351±32.9 pg/ml respectively (p=0.0001). Red bloodcell indices were found to show statistically significant difference between cases and controls(p=0.001). Conclusion: Serum cobalamin deficiency was noted in both Helicobacter pyloripositive and controls, however deficiency was more pronounced in Helicobacter pylori positivesubjects.

Quality of life in type 2 diabetics with gastroesophageal reflux disease: a case control study

2013 ◽  
Vol 45 (4) ◽  
pp. 194-199 ◽  
Author(s):  
R. Promberger ◽  
A. Spitzer ◽  
J. Ott ◽  
J. Lenglinger ◽  
W. Eilenberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Case Control Study ◽  
Case Control ◽  
Type 2 Diabetics ◽  
Control Study

scholarly journals Helicobacter pylori Infection as a Risk Factor for Hepatocellular Carcinoma: A Case-Control Study in Ethiopia

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Hailemichael Desalegn Mekonnen ◽  
Henok Fisseha ◽  
Tewodros Getinet ◽  
Fisseha Tekle ◽  
Peter R. Galle
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Case Control Study ◽  
Clinical History ◽  
Case Control ◽  
Chronic Liver ◽  
P Value ◽  
H Pylori ◽  
Control Study

Background and Aims.Hepatocellular carcinoma is a major cause of cancer death worldwide, accounting for over half a million deaths per year. Its incidence varies with geographic locations and the type of etiologic factors. In Ethiopia, unidentified causes of liver disease are of sizeable proportion. Recent studies have shown an association of H. pylori infection with different spectrums of chronic liver disease. This study was conducted at St. Paul’s Hospital Millennium Medical College in Ethiopia and assesses liver cancer and the association with H. pylori infection.Method.A prospective case-control study conducted on patients with chronic liver disease presenting with a suspicious liver lesion and diagnosed to have HCC in the Gastrointestinal (GI) Clinic of St. Paul’s Hospital MMC from Dec 30, 2016, to Nov 1, 2017 G.C. Descriptive surveys on clinical history and physical examination and laboratory profiles were obtained, and the clinical course of the patients including the type of treatment was followed prospectively. Control cases were taken from adult patients without evidence of liver disease in the internal medicine clinic coming for routine evaluation. After collection data were analyzed using SPSS version 23 and associations were assessed using chi-square test. Binary logistic regression was used to assess the association of HCC with different variables and H. pylori infection. All variables with p-value <0.05 were considered as statistically significant.Results.One hundred twenty patients were analyzed with equal representation of cases and controls. The majority of patients with HCC were male with a mean age of 36 years. Older age adjusted Odds Ratio (AOR) (95%CI, p-value) 1.07(1.03-1.09, <0.001), viral hepatitis B (AOR) (95%CI, p-value) 6.19 (1.92-19.93, 0.002), and H. pylori infection (AOR) (95%CI, p-value) 5.22 (2.04–13.31, <0.001) were statistically significantly associated with HCC.Conclusion.H. pylori infection is associated with HCC in this case-control study. This study supports the emerging evidence of H. pylori association with other extra-gastric manifestations.

scholarly journals Inverse association between Helicobacter pylori infection and childhood asthma in Greece: a case-control study

GERMS ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 182-187 ◽  
Author(s):  
Christina Tsigalou ◽  
Theocharis G Konstantinidis ◽  
Dimitrios Cassimos ◽  
Alexandros Karvelas ◽  
Anastasia Grapsa ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Childhood Asthma ◽  
Case Control Study ◽  
Case Control ◽  
Helicobacter Pylori Infection ◽  
Inverse Association ◽  
Control Study

scholarly journals A Case-Control Study of Association of Helicobacter pylori Infection With Morbid Obesity in Taiwan

2005 ◽  
Vol 165 (13) ◽  
pp. 1552 ◽  
Author(s):  
Ming-Shiang Wu ◽  
Wei-Jei Lee ◽  
Hsih-Hsi Wang ◽  
Shi-Pei Huang ◽  
Jaw-Town Lin
Keyword(s):  
Morbid Obesity ◽  
Helicobacter Pylori ◽  
Case Control Study ◽  
Case Control ◽  
Helicobacter Pylori Infection ◽  
Control Study
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