scholarly journals Collagen dressing versus silver sulfadiazine dressings in partial thickness burns-prospective study

2021 ◽  
Vol 8 (5) ◽  
pp. 1496
Author(s):  
Sunil Mathew ◽  
Nawaz Shariff ◽  
Sreeramulu P. N. ◽  
Krishnaprasad .
Keyword(s):  
Cost Effective ◽  
Healing Time ◽  
Research Centre ◽  
Painful Condition ◽  
Partial Thickness ◽  
Group I ◽  
Reduction Of Pain ◽  
Prolonged Hospital ◽  
Partial Thickness Burns ◽  
Silver Sulphadiazine

Background: Occurrence, pathophysiology and management of burns is complex. It is a painful condition and topical management of burns is a challenging task. An ideal topical dressing which allows faster healing with reduction of pain, prevent infection, leads to a good scar formation and which is cost effective is required. Thus, there is a need to study the effectiveness of collagen dressing in comparison with conventional silver sulphadiazine dressing (SSD) in terms of pain score, healing time and cost efficiency.Methods: This prospective randomized comparative study includes patients with partial thickness burns, <40% BSA and not older than 48 hours, admitted to department of surgery of RL Jalappa hospital and research centre Tamaka Kolar during the period December 2019 to March 2020. 34 patients were studied, these patients were randomized into collagen dressing or silver sulphadiazine dressing group of 17 each.Results: The 34 patients admitted with partial thickness burns, <40% BSA were divided into two equal and comparable groups. Patients subjected to collagen dressings were classified under group I and those who underwent 1% silver sulphadiazine dressings were classified as group II.Conclusions: The collagen dressing is more cost effective than SSD. SSD has disadvantage of the large number of dressings prolonged hospital stay, amount pain, loss of time and labour of the patient and the accompanying person which make collagen dressing more cost effective as it is most of the time a single dressing.

scholarly journals Management of facial burns

2020 ◽  
Vol 8 ◽  
Author(s):  
David G Greenhalgh
Keyword(s):  
Skin Grafting ◽  
Healing Time ◽  
The Body ◽  
Full Thickness ◽  
Partial Thickness ◽  
Facial Burns ◽  
The Face ◽  
Partial Thickness Burns

Abstract Burns to the face affect a part of the body that cannot be hidden and thus exposes potentially major changes in appearance to society. Therefore, it is incumbent upon the caregiver to optimize healing and minimize scarring. The goal for partial-thickness burns is to have them heal within 2–3 weeks to minimize healing time. For full-thickness burns there needs to be strategies to optimize the outcomes for skin grafting and minimize scarring. The goal of this review is to discuss the best way to improve the outcomes of these devastating injuries.

scholarly journals Ultrasonographic findings of re-epithelialized skin after partial-thickness burns

2018 ◽  
Vol 6 ◽  
Author(s):  
Jong Dae Kim ◽  
Suk Joon Oh ◽  
Sun Gyu Kim ◽  
Song Vogue Ahn ◽  
Yu Jin Jang ◽  
...  
Keyword(s):  
Medical Records ◽  
Normal Skin ◽  
Healing Time ◽  
Ultrasound Images ◽  
Strongly Correlated ◽  
Varying Thickness ◽  
Partial Thickness ◽  
The Difference ◽  
Partial Thickness Burns ◽  
The Relationship

Abstract Background This study aimed to investigate the difference between ultrasonographic findings of normal skin and those of re-epithelialized skin after partial-thickness burns and to evaluate the relationship between these findings and clinical outcomes. Methods This study retrospectively analysed the ultrasound images of re-epithelialized skin after partial-thickness burns and contralateral normal skin from January 2016 to December 2016. A total of 155 lesions from 148 patients were analysed with ultrasound images, and healing time was documented. The scar status of each lesion was evaluated through medical records and photographs. We analysed the difference in ultrasonographic findings between normal skin and re-epithelialized skin after partial-thickness burns and statistically analysed the relationship between healing time, scar status and ultrasonographic findings. Results The re-epithelialized skin after partial-thickness burns was significantly thicker than the contralateral normal skin, and the echogenicity was significantly lower. The ultrasound images of the re-epithelialized skin after partial-thickness burns showed the characteristic findings of low-echogenic bands (LEB), and the proportion of LEB thickness is strongly correlated with healing time. In the multivariate analysis of scar status, only the proportion of LEB thickness was statistically significant. Conclusion In this study, we found that there were ultrasonographic differences between re-epithelialized skin after partial-thickness burns and normal skin and that an LEB of varying thickness was formed after re-epithelialization. The thickness of the LEB in re-epithelialized skin after partial-thickness burns increased with healing time and was related to scar status.

A comparative study of 1% silver sulphadiazine (Flammazine®) versus an enzyme alginogel (Flaminal®) in the treatment of partial thickness burns

Burns ◽  
2013 ◽  
Vol 39 (6) ◽  
pp. 1234-1241 ◽  
Author(s):  
Henk Hoeksema ◽  
David Vandekerckhove ◽  
Jozef Verbelen ◽  
Alexander Heyneman ◽  
Stan Monstrey
Keyword(s):  
Comparative Study ◽  
Partial Thickness ◽  
Partial Thickness Burns ◽  
Silver Sulphadiazine

Microbial cellulose dressing compared with silver sulphadiazine for the treatment of partial thickness burns: A prospective, randomised, clinical trial

Burns ◽  
2018 ◽  
Vol 44 (8) ◽  
pp. 1982-1988 ◽  
Author(s):  
Ahmed Aboelnaga ◽  
Moustafa Elmasry ◽  
Osama A. Adly ◽  
Mohamed A. Elbadawy ◽  
Ashraf H. Abbas ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomised Clinical Trial ◽  
Microbial Cellulose ◽  
Partial Thickness ◽  
Partial Thickness Burns ◽  
Silver Sulphadiazine

scholarly journals The Introduction of a Protocol for the Use of Biobrane for Facial Burns in Children

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
A. D. Rogers ◽  
S. Adams ◽  
H. Rode
Keyword(s):  
Standard Of Care ◽  
Healing Time ◽  
Partial Thickness ◽  
Facial Burns ◽  
Aesthetic Results ◽  
Cadaver Skin ◽  
The Face ◽  
One Year ◽  
Partial Thickness Burns ◽  
Historical Controls

Biobrane has become an indispensible dressing with three established indications in acute burns care at our institution: (1) as the definitive dressing of superficial partial thickness facial burns, (2) after tangential excision of deep burns when autograft or cadaver skin is unavailable, and (3) for graft reduction. This paper details our initial experience of Biobrane for the management of superficial partial thickness facial burns in children and the protocol that was compiled for its optimal use. A retrospective analysis of theatre records, case notes and photographs was performed to evaluate our experience with Biobrane over a one-year period. Endpoints included length of stay, analgesic requirements, time to application of Biobrane, healing times, and aesthetic results. Historical controls were used to compare the results with our previous standard of care. 87 patients with superficial partial thickness burns of the face had Biobrane applied during this period. By adhering to the protocol we were able to demonstrate significant reductions in hospital stay, healing time, analgesic requirements, nursing care, with excellent cosmetic results. The protocol is widely accepted by all involved in the optimal management of these patients, including parents, anaesthetists, and nursing staff.

The Optimal Treatment for Partial Thickness Burns: A Cost-Utility Analysis of Skin Allograft vs. Topical Silver Dressings

2020 ◽  
Vol 41 (3) ◽  
pp. 450-456 ◽  
Author(s):  
Clifford C Sheckter ◽  
Nickolas L Meyerkord ◽  
Yunna L Sinskey ◽  
Pariss Clark ◽  
Katarina Anderson ◽  
...  
Keyword(s):  
Sensitivity Analysis ◽  
Probabilistic Sensitivity Analysis ◽  
Cost Effective ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis ◽  
Skin Allograft ◽  
Partial Thickness ◽  
Partial Thickness Burns ◽  
Quality Adjusted Life

Abstract Introduction Partial thickness burns not undergoing surgical excision are treated with topical silver products including silver sulfadiazine (SSD) and Mepilex Ag. Skin allograft is a more costly alternative that acts as definitive wound coverage until autogenous epithelialization. Economic constraints and the movement toward value-based care demand cost and outcome justification prior to adopting more costly products. Methods A cost-utility analysis was performed comparing skin allograft to SSD and Mepilex Ag using decision tree analysis. The base case modeled a superficial partial thickness 20% total body surface area burn. Utilities were derived from expert opinion on the basis of personal experience. Costs were derived from 2019 Medicare payments. Quality adjusted life years were calculated using rollback method assuming standard life expectancies in the United States. Probabilistic sensitivity analysis was performed to asses model robustness. Results The incremental costs of skin allograft to Mepilex Ag and SSD were $907.71 and $1257.86, respectively. The incremental quality adjusted life year (QALY) gains from allograft over Mepilex Ag and SSD were 0.011 and 0.016. This yielded an incremental cost-utility ratio for allograft vs. Mepilex Ag of $84,189.29/QALY compared with an incremental cost-utility ratio of $79,684.63/QALY for allograft vs. SSD. Assuming willingness-to-pay thresholds of $100,000/QALY, probabilistic sensitivity analysis demonstrated that allograft was cost effective to Mepilex Ag in 62.1% of scenarios, and cost effective to SSD in 64.9% of simulations. Conclusion Skin allograft showed greater QALYs compared with topical silver dressings at a higher cost. Depending on willingness-to-pay thresholds, skin allograft may be a considered a cost-effective treatment of partial-thickness burns.

scholarly journals Porcine Xenograft and Epidermal Fully Synthetic Skin Substitutes in the Treatment of Partial-Thickness Burns: A Literature Review

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 432
Author(s):  
Herbert L. Haller ◽  
Sigrid E. Blome-Eberwein ◽  
Ludwik K. Branski ◽  
Joshua S. Carson ◽  
Roselle E. Crombie ◽  
...  
Keyword(s):  
Healing Time ◽  
Subsequent Treatment ◽  
Skin Substitute ◽  
Skin Substitutes ◽  
Burn Treatment ◽  
Advantages And Disadvantages ◽  
Partial Thickness ◽  
Partial Thickness Burn ◽  
Partial Thickness Burns ◽  
Porcine Xenograft

Background and Objectives: Porcine xenografts have been used successfully in partial thickness burn treatment for many years. Their disappearance from the market led to the search for effective and efficient alternatives. In this article, we examine the synthetic epidermal skin substitute Suprathel® as a substitute in the treatment of partial thickness burns. Materials and Methods: A systematic review following the PRISMA guidelines has been performed. Sixteen Suprathel® and 12 porcine xenograft studies could be included. Advantages and disadvantages between the treatments and the studies’ primary endpoints have been investigated qualitatively and quantitatively. Results: Although Suprathel had a nearly six times larger TBSA in their studies (p < 0.001), it showed a significantly lower necessity for skin grafts (p < 0.001), and we found a significantly lower infection rate (p < 0.001) than in Porcine Xenografts. Nonetheless, no significant differences in the healing time (p = 0.67) and the number of dressing changes until complete wound healing (p = 0.139) could be found. Both products reduced pain to various degrees with the impression of a better performance of Suprathel® on a qualitative level. Porcine xenograft was not recommended for donor sites or coverage of sheet-transplanted keratinocytes, while Suprathel® was used successfully in both indications. Conclusion: The investigated parameters indicate that Suprathel® to be an effective replacement for porcine xenografts with even lower subsequent treatment rates. Suprathel® appears to be usable in an extended range of indications compared to porcine xenograft. Data heterogeneity limited conclusions from the results.

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