Impact of health education on attitude regarding oral anti-diabetic drug adherence in type 2 diabetes mellitus, Bengaluru

Background: Diabetes mellitus, especially type 2 diabetes is an emerging global epidemic and public health problem and associated with high morbidity and mortality among patients. Positive attitude is important for the management of drug adherence in diabetes, hence the present study was taken to assess the effectiveness of health education on oral anti-diabetic drug adherence.Methods: A descriptive and interventional study was conducted at urban health training centre of a medical college, Bengaluru from November 2015 to March 2016. A total of 70 type 2 diabetes mellitus patients only on oral anti-diabetic drugs willing to give informed consent were included in the study. A pre-tested semi-structured proforma was administered and information about socio-demographic profile, and impact of health education intervention on attitude was obtained.Results: Most of the subjects were female (80%), in the age group of 35-45 yrs (34%), illiterate (40%), unemployed (67%) with Class IV (78%) socio-economic status according to modified Kuppuswamy Classification 2014. The mean ±SD age was 52.47±11.06 years. Significant improvement in attitude regarding adherence to oral anti-diabetic medication was found in study subjects following health education intervention.Conclusions: The study revealed that health education regarding the importance of drug adherence is needed to build positive attitude in study subjects.

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Pathophysiology of type 2 diabetes mellitus in youth: the evolving chameleon

Arquivos Brasileiros de Endocrinologia & Metabologia ◽

10.1590/s0004-27302009000200008 ◽

2009 ◽

Vol 53 (2) ◽

pp. 165-174 ◽

Cited By ~ 22

Author(s):

Hala Tfayli ◽

Silva Arslanian

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Beta Cell ◽

Polycystic Ovary ◽

Significant Proportion ◽

Public Health Problem ◽

Family History Of Diabetes ◽

Beta Cell Failure

Type 2 diabetes mellitus (T2DM) in children and adolescents is an important Public Health problem against the backdrop of the epidemic of childhood obesity. The clinical presentation of T2DM in youth is heterogeneous from minimal symptomatology to diabetic ketoacidosis. The increasing rates of youth T2DM have paralleled the escalating rates of obesity, which is the major risk factor impacting insulin sensitivity. Additional risk factors include minority race, family history of diabetes mellitus, maternal diabetes during pregnancy, pubertal age group and conditions associated with insulin resistance (IR) - such as polycystic ovary syndrome (PCOS). The pathophysiology of T2DM has been studied extensively in adults, and it is widely accepted that IR together with beta-cell failure are necessary for the development of clinical diabetes mellitus in adulthood. However, pathophysiologic studies in youth are limited and in some cases conflicting. Similar to adults, IR is a prerequisite, but beta-cell failure is necessary for progression from normal glucose tolerance to prediabetes and frank diabetes in youth. Even though rates of T2DM in youth are increasing, the overall prevalence remains low if compared with type 1 diabetes mellitus (T1DM). However, as youth with T1DM are becoming obese, the clinical distinction between T2DM and obese T1DM has become difficult, because of the overlapping clinical picture with evidence of islet cell autoimmunity in a significant proportion of clinically diagnosed youth with T2DM. The latter are most likely obese children with autoimmune T1DM who carry a misdiagnosis of T2DM. Further research is needed to probe the pathophysiological, immunological, and metabolic differences between these two groups in the hopes of assigning appropriate therapeutic regimens. These challenges combined with the evolving picture of youth T2DM and its future complications provide unending opportunities for acquisition of new knowledge in the field of childhood diabetes.

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"The group facilitates everything": meanings patients with type 2 diabetes mellitus assigned to health education groups

Revista Latino-Americana de Enfermagem ◽

10.1590/0104-1169.0056.2506 ◽

2014 ◽

Vol 22 (6) ◽

pp. 980-987 ◽

Cited By ~ 4

Author(s):

Lucas Pereira de Melo ◽

Edemilson Antunes de Campos

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Health Education ◽

Healthcare Workers ◽

Participant Observation ◽

Ethnographic Study ◽

Public Health Care ◽

Structured Interviews

OBJECTIVE: to interpret the meanings patients with type 2 diabetes mellitus assign to health education groups.METHOD: ethnographic study conducted with Hyperdia groups of a healthcare unit with 26 informants, with type 2 diabetes mellitus, and having participated in the groups for at least three years. Participant observation, social characterization, discussion groups and semi-structured interviews were used to collect data. Data were analyzed through the thematic coding technique.RESULTS: four thematic categories emerged: ease of access to the service and healthcare workers; guidance on diabetes; participation in groups and the experience of diabetes; and sharing knowledge and experiences. The most relevant aspect of this study is the social use the informants in relation to the Hyperdia groups under study.CONCLUSION: the studied groups are agents producing senses and meanings concerning the process of becoming ill and the means of social navigation within the official health system. We expect this study to contribute to the actions of healthcare workers coordinating these groups given the observation of the cultural universe of these individuals seeking professional care in the various public health care services.

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Association of KCNQ1rs2237892C ⟶ T Gene with Type 2 Diabetes Mellitus: A Meta-Analysis

Journal of Diabetes Research ◽

10.1155/2021/6606830 ◽

2021 ◽

Vol 2021 ◽

pp. 1-9

Author(s):

Wen-Jia Han ◽

Jian-Yi Deng ◽

Hua Jin ◽

Li-Ping Yin ◽

Jin-Xia Yang ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Gene Polymorphism ◽

Genetic Model ◽

Meta Analysis ◽

High Morbidity ◽

Genome Wide Association Studies ◽

Asian Populations

Background. Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases in adults, causing high morbidity and mortality worldwide. In recent years, the prevalence of T2DM has been increasing significantly, and genome-wide association studies (GWAS) have shown that KCNQ1 significantly increases the risk of T2DM. Objective. To find large-scale evidence on whether the KCNQ1rs2237892C⟶T gene polymorphism is associated with T2DM susceptibility. Methods. A comprehensive review of the Chinese and English literature on the association of T2DM with KCNQ1rs2237892 is published by PubMed and Baidu Academic. The included literature was part or all of the studied loci which were evaluated for association with T2DM. Forest plots were made of the included literature to analyze the association of KCNQ1 with polymorphisms of the studied loci, and funnel plots and Egger’s test were used to evaluate the publication bias of the selected included literature. Results. Ten case-control studies including a total of 7027 cases and 8208 controls met our inclusion criteria. Allele (C allele frequency distribution) (OR: 1.19; 95% CI: 0.87,1.62; P < 0.00001 ), recessive (OR: 0.73; 95% CI: 0.45,1.18; P < 0.00001 ) genetic model under the full population was observed between KCNQ1rs2237892C⟶T gene polymorphism and T2DM without a significant relationship. In a stratified analysis by race, a meaningful association was found in non-Asian populations under the allelic genetic model, but no association was found in Asian populations. Conclusion. This meta-analysis showed no significant association between the rs2237892 polymorphism of the KCNQ1 gene and the risk of T2DM.

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Monitoring System for Glycemic Control in Patients with Type 2 Diabetes Mellitus, Based on Mobile Technology, Telemetry, and Health Education

Proceedings of the 4th World Congress on Electrical Engineering and Computer Systems and Science ◽

10.11159/icbes18.156 ◽

2018 ◽

Author(s):

Eduardo Toledo ◽

Daniel Cárdenas ◽

Miguel Angulo ◽

Edgard Oporto

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Glycemic Control ◽

Health Education ◽

Monitoring System ◽

Mobile Technology

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The Effect of Health Education on Control Glycemic at Type 2 Diabetes Mellitus Patients

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2020.3371 ◽

2020 ◽

Vol 8 (E) ◽

pp. 133-137

Author(s):

Rusdiana Rusdiana ◽

Maya Savira ◽

Sry Suryani Widjaja ◽

Dedi Ardinata

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Health Care ◽

Type 2 Diabetes Mellitus ◽

Glycemic Control ◽

Health Education ◽

Diabetic Patients ◽

The Mean ◽

Educational Course

AIM: The aim of this study was to evaluate the effect of short-term education on glycemic control (glycated hemoglobin [HbA1c] and fasting blood sugar [FBS]) among type 2 diabetes mellitus patients attending to primary health care (PHC) in Medan Johor of North Sumatera, Indonesia. METHODS: The study was performed on type 2 diabetes mellitus patients in Johor PHC, Medan of North Sumatera, on 40 patients with type 2 diabetes mellitus. We took the samples of all the patients of type 2 diabetes mellitus who attend PHC in Medan Johor. The patients received for 3 months intervention by education. An educational course of diabetes together with exercise training and nutritional education was designed for the study population in order to increase the patients’ knowledge and attitude toward diabetes and to increase their participation in the self-monitoring of glycemic control. Samples of FBS and HbA1c were recorded for each patient at the time of the baseline survey, then health education was conducted to the diabetic patients of both sexes attending PHC. The patients received standard advice on diet management and variation about activity. We put HbA1c <6.5% as cut limit for the control of diabetes mellitus. RESULTS: All 40 type 2 diabetes patients completed the educational course. The mean of age of the samples is 62.53 years old, the mean of body mass index was 24.81 kg/m, and the mean of waist size was 92.15 cm. Before the education, the mean of FBS level was 238.83 mg/dl and the mean of Hba1c value is 8.90%. After education, the FBS was 216.88 mg/dl, the mean of HbA1c value was 8.74%. CONCLUSION: The effect of health education in Johor Public Health Care Medan city reduced glycemic control (FBS) in type 2 diabetes mellitus patients, North Sumatera, Indonesia.

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