scholarly journals Non-salivary and non-intestinal orbital adenocarcinoma

2020 ◽  
Vol 6 (5) ◽  
pp. 983
Author(s):  
Pedro Clarós ◽  
Aymar Diandaga Maleka ◽  
Agnieszka Walag ◽  
Andrés Clarós
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Clinical Case ◽  
Histopathological Examination ◽  
Metastatic Potential ◽  
Low Grade ◽  
High Grade ◽  
Resonance Imaging ◽  
Tumor Biopsy ◽  
The Subject

<p>The non-salivary and non-intestinal adenocarcinomas are glandular tumors that include cases of low grade with low metastatic potential and high-grade ones, with aggressive metastatic potential. We present a clinical case of a 47 years old patient, referred to an ENT specialist because of swelling of the inner corner of right eye. Computed tomography (CT) and magnetic resonance imaging showed a proliferation process. The histopathological examination of the tumor biopsy revealed a high grade, non-salivary and non-intestinal orbital adenocarcinoma. Afterwards we review the literature on the subject. The primary non-salivary and non-intestinal orbital adenocarcinoma is characterized by locoregional aggressiveness, making treatment difficult and often mutilating. The prognosis is generally unfavourable. The clinician must exclude a malignant process of lacrimal sac in any patient presenting with a mass of the inner corner of the eye, with the help of the CT associated with magnetic resonance imaging. At the slightest doubt, the biopsy must be obtained. The treatment is multidisciplinary.</p>

Role of magnetic resonance imaging in prediction of chondrosarcoma of bone grade

2021 ◽  
pp. 21-24
Author(s):  
A. V. Fedorova ◽  
N. V. Kochergina ◽  
A. B. Bludov ◽  
I. V. Boulycheva ◽  
E. A. Sushentsov ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Diagnostic Value ◽  
Low Grade ◽  
High Grade ◽  
Resonance Imaging ◽  
Accurate Definition ◽  
Definition Of ◽  
Decisive Rule

Purpose. Determining the diagnostic value of magnetic resonance imaging in the accurate definition of chondrosarcoma of bone grade at the pre-surgery examination. Material and methods. We analyzed examination data (magnetic resonance imaging with no contrast enhancement) of 70 patients with chondrosarcoma (35 patients with low-grade chondrosarcoma and 35 patients with high grade chondrosarcoma). Informative weighted coefficients were determined separately for ‘learning’ and ‘examination’ samples. On the basis of weighted coefficients, the decisive rule was created for differentiation between low-grade and high-grade chondrosarcoma. Results. The sensitivity of the method was 87.0%, specificity was 95.6%, total correct classification was 91.03%. Conclusion. Magnetic resonance imaging is a highly informative method for prediction of chondrosarcoma grade at the pre-surgery examination.

MUCINOUS LOW-GRADE ADENOCARCINOMA ARISING IN AN INTRACRANIAL ENTEROGENOUS CYST

Neurosurgery ◽  
2008 ◽  
Vol 62 (4) ◽  
pp. E972-E973 ◽  
Author(s):  
Marco Gessi ◽  
Federico G. Legnani ◽  
Emanuela Maderna ◽  
Cecilia Casali ◽  
Carlo L. Solero ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Malignant Transformation ◽  
Histopathological Examination ◽  
Present Report ◽  
Cranial Nerves ◽  
Residual Tumor ◽  
Magnetic Resonance Imaging Scan ◽  
Low Grade ◽  
Resonance Imaging

Abstract OBJECTIVE Enterogenous cysts (ECs) of the central nervous system are developmental malformations that occur in the spinal canal, posterior fossa, or cerebral hemispheres. They are usually benign lesions, and malignant transformation is rare. To date, only three cases of malignant transformation have been reported in the literature. We present a case of a cerebellopontine EC showing foci of epithelial dysplasia and malignant transformation into a low-grade papillary mucinous adenocarcinoma. CLINICAL PRESENTATION A 25 year-old man with a 6-year history of hypoacusia presented to our department with facial nerve deficit, visual disturbances, and gait instability. A magnetic resonance imaging scan demonstrated a multiloculated cerebellopontine angle cyst with supratentorial hydrocephalus. INTERVENTION A retrosigmoidal approach was used to achieve cyst removal. This was followed several months later by ventriculoperitoneal shunt placement. The cyst was adherent to the brainstem, cranial nerves, and vessels, and it resembled a thin encapsulated structure filled with mucinous-like substance. No solid component was identified. Histopathological examination revealed an EC with foci of malignant transformation in a mucinous papillary adenocarcinoma. Magnetic resonance imaging was performed 5 months postoperatively due to progressive clinical worsening; this scan revealed lesion recurrence with severe brainstem compression. Emergency surgery was performed, and a large decompression was achieved. Subsequent follow-up computed tomographic scans showed progression of the residual tumor. The patient's neurological condition rapidly worsened, ultimately resulting in death. CONCLUSION The present report suggests that a careful histological examination of all ECs after surgery should be made to exclude dysplastic foci or carcinomatous transformation. Although the clinical behavior of ECs with malignant trasformation is unpredictable, surgery remains the treatment of choice. The use of possible adjuvant chemo- or radiotherapy has not been established.

Utility of intravoxel incoherent motion magnetic resonance imaging and arterial spin labeling for recurrent glioma after bevacizumab treatment

2018 ◽  
Vol 59 (11) ◽  
pp. 1372-1379 ◽  
Author(s):  
Fuminori Miyoshi ◽  
Yuki Shinohara ◽  
Atsushi Kambe ◽  
Keita Kuya ◽  
Atsushi Murakami ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Diffusion Coefficient ◽  
Magnetic Resonance ◽  
Tumor Progression ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Intravoxel Incoherent Motion ◽  
Low Grade ◽  
High Grade ◽  
Resonance Imaging

Background Detecting recurrence of glioma on magnetic resonance imaging (MRI) is getting more and more important, especially after administration of new anti-tumor agent. However, it is still hard to identify. Purpose To examine the utility of intravoxel incoherent motion (IVIM) MRI and arterial spin labeling-cerebral blood flow (ASL-CBF) for recurrent glioma after initiation of bevacizumab (BEV) treatment. Material and Methods Thirteen patients (7 men, 6 women; age range = 41–82 years) with glioma (high grade, n = 11; low grade, n = 2) were enrolled in the study. IVIM parameters including apparent diffusion coefficient (ADC), true diffusion coefficient (D), and perfusion fraction (f) were obtained with 14 different b-values. We identified tumor progression during BEV therapy by MRI monitoring consisting of diffusion-weighted imaging (DWI), fluid-attenuated inversion recovery (FLAIR) imaging, and contrast-enhanced T1-weighted (CE-T1W) imaging by measuring tumor area. We also measured each parameter of IVIM and ASL-CBF, and calculated relative ADC (rADC), relative D (rD), relative f (rf), and relative CBF (rCBF) by obtaining the ratio between each area and the contralateral cerebral white matter. We calculated the rate of change (Δ) by subtracting values from those from the preceding MRI study, and obtained Spearman’s rank correlation coefficient (rs). Results Tumor progression was identified in nine patients (high grade, n = 7; low grade, n = 2). Negative correlations were identified between ΔrD and ΔDWI area (rs = –0.583), and between ΔrD and ΔCE-T1W imaging area (rs = –0.605). Conclusion Tumor progression after BEV treatment can be identified by decreasing rD.

Diffusion tensor analysis of peritumoral edema using lambda chart analysis indicative of the heterogeneity of the microstructure within edema

2005 ◽  
Vol 102 (2) ◽  
pp. 336-341 ◽  
Author(s):  
Ken-ichi Morita ◽  
Hitoshi Matsuzawa ◽  
Yukihiko Fujii ◽  
Ryuichi Tanaka ◽  
Ingrid L. Kwee ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Low Grade ◽  
High Grade ◽  
Peritumoral Edema ◽  
Resonance Imaging ◽  
Content Type ◽  
Water Diffusivity ◽  
High Grade Gliomas ◽  
Fine Print

Object. Histopathological studies indicate that cerebral edema associated with tumors (peritumoral edema) does not represent a single pathophysiological or clinical entity. In this study the authors investigated peritumoral edema by performing lambda chart analysis (LCA), a noninvasive technique that can be used to make visible and analyze apparent water diffusivity in tissues in vivo, and assessed the utility of LCA in differentiating high-grade gliomas from nonglial tumors. Methods. The water diffusivity characteristics of peritumoral edema associated with four tumor groups—12 high-grade gliomas, five low-grade gliomas, 11 metastatic tumors, and 15 meningiomas—were assessed in 43 patients by performing magnetic resonance imaging with the aid of a 3-tesla magnetic resonance imaging system. In all tumor groups, peritumoral edema exhibited greater trace values and reduced anisotropy compared with normal white matter. Edema associated with high-grade gliomas had significantly higher trace values than edema associated with the other three tumor groups, although the anisotropic angles of those groups were comparable. Conclusions. Lambda chart analysis identified two distinct types of peritumoral edema: edema associated with high-grade gliomas and edema associated with low-grade gliomas or nonglial tumors. The apparent water diffusivity was significantly greater in high-grade gliomas, whereas the anisotropy in these lesions was comparable to that of edema in other tumors. These findings indicated that water movement in areas of edema, predominantly in the extracellular spaces, was less restricted in high-grade gliomas, a phenomenon that likely reflected the destruction of the extracellular matrix ultrastructure by malignant cell infiltration and consequently greater water diffusion. Although preliminary, this study indicates that LCA could be used as a clinical tool for differentiating high-grade gliomas and for evaluating the extent of cellular infiltration.

Multiparametric Magnetic Resonance Imaging for Discriminating Low-Grade From High-Grade Prostate Cancer

2015 ◽  
Vol 50 (8) ◽  
pp. 490-497 ◽  
Author(s):  
Eline K. Vos ◽  
Thiele Kobus ◽  
Geert J.S. Litjens ◽  
Thomas Hambrock ◽  
Christina A. Hulsbergen-van de Kaa ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Low Grade ◽  
High Grade ◽  
Resonance Imaging ◽  
Multiparametric Magnetic Resonance Imaging

Multiple myeloma manifesting as an intraventricular brain tumor

2009 ◽  
Vol 110 (4) ◽  
pp. 737-739 ◽  
Author(s):  
Joo-Hun David Eum ◽  
Astrid Jeibmann ◽  
Werner Wiesmann ◽  
Werner Paulus ◽  
Heinrich Ebel
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Myeloma ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Lateral Ventricle ◽  
Histopathological Examination ◽  
Brain Parenchyma ◽  
Resonance Imaging

Primary intracerebral manifestation of multiple myeloma is rare and usually arises from the meninges or brain parenchyma. The authors present a case of multiple myeloma primarily manifesting within the lateral ventricle. A 67-year-old man was admitted with headache accompanied by slowly progressing right hemiparesis. Magnetic resonance imaging showed a large homogeneous contrast-enhancing intraventricular midline mass and hydrocephalus. The tumor was completely resected, and histopathological examination revealed plasmacytoma. After postoperative radio- and chemotherapy, vertebral osteolysis was detected as a secondary manifestation of multiple myeloma.

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