scholarly journals Visual analogue score and endoscopic domain analysis to assess the outcome of microdebrder in sinonasal diseases

2021 ◽  
Vol 7 (4) ◽  
pp. 633
Author(s):  
Anil S. Harugop ◽  
O. Padmavathy ◽  
Shama A. Bellad ◽  
Reshma Ramesh ◽  
Rajesh R. Havaldar
Keyword(s):  
Visual Analogue Scale ◽  
Scoring System ◽  
Analogue Scale ◽  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Postoperative Outcome ◽  
Visual Analogue Score ◽  
Care Hospital ◽  
Sinonasal Disease

<p class="abstract"><strong>Background: </strong>The use of microdebrider in various sinonasal diseases have been sparingly understood. The present study aims to find out the effectiveness of a microdebrider in different sinonasal diseases by using each domain of visual analogue scale (VAS) and confirming the findings by diagnostic nasal endoscopy.</p><p class="abstract"><strong>Methods: </strong>A prospective observational study was done among patients with sinonasal disease between January 2019 to March 2020 in our tertiary care hospital. A subjective visual analogue scale (VAS) was completed by every patient for all domains according to Lund and Mackay symptom scoring system. Using Lund Kennedy scoring, polyp, edema and discharge were assessed preoperatively. Patients were followed up for 1 week, 6 weeks and 3 months. At 3 months both VAS and Lund Kennedy scoring was done. Post operatively scarring and crusting were assessed separately.</p><p class="abstract"><strong>Results: </strong>There was a significant improvement in domains post operatively in all the diseases considered (p=0.001). In Lund Kennedy endoscopic scoring system there was significant improvement in all the domain that was taken into consideration (p=0.001). Inter-disease domain comparison was also made.</p><p class="abstract"><strong>Conclusions:</strong> The study substantiates the use of microdebrider in various sinonasal disease. Microdebrider being a modern multipurpose instrument plays a significant role in complete clearance of the disease with good postoperative outcome.</p>

scholarly journals Assessment of adverse drug reaction profile of the disease-modifying anti-rheumatic drugs at the department of orthopaedics in a tertiary care hospital, Silchar, Assam, India

2019 ◽  
Vol 8 (5) ◽  
pp. 1007
Author(s):  
Vijoy S. Kairi ◽  
Pinaki Chakravarty ◽  
Arun Kumar Sipani
Keyword(s):  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Early Recognition ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Case Record ◽  
Medical College ◽  
Disease Modifying ◽  
Reaction Profile

Background: The mainstay of treatment of Rheumatoid Arthritis (RA) is the use of the disease-modifying anti-rheumatic drugs (DMARDs). Methotrexate, sulfasalazine and hydroxychloroquine are some of the DMARDs which are used in combination for the treatment of RA. The current study was undertaken to assess the adverse drug reactions (ADRs) of DMARDs that are commonly encountered with the treatment of RA.Methods: The present study was designed as a prospective, observational study on newly diagnosed patients with RA. Patients diagnosed with RA above 18 years (excluding pregnant women) of either sex who were prescribed DMARDs in combination were included. ADRs reported spontaneously by the patients and also responses obtained in a questionnaire related to likely ADRs from the patients was recorded in the case record form. Statistical analysis was done using graph pad and p value <0.05 was considered to be statistically significant.Results: A total of 47 patients attending the Outpatient Department of Orthopaedics, Silchar Medical College and Hospital, Silchar, Assam, India were screened for the study. ADRs were monitored up to the last visit on 41 patients excluding the patients who were lost and who were not able to adhere to the treatment. A total of 27 ADRs were reported from 19 ADR forms. Gastrointestinal manifestations were the most common adverse effects of combination DMARDs seen in 10 patients (24.39%). Severity assessment done using modified Hartwig and Siegel scale that showed majority of the ADRs were mild (74.07%).Conclusions: Present study showed that DMARDs are well-tolerated and have an acceptable toxicity profile as majority of ADRs seen were mild. It was however difficult to prevent the occurrence of ADRs. Proper monitoring of therapy is needed for early recognition of ADRs.

scholarly journals EFFECTIVENESS OF AUTOLOGOUS SERUM THERAPY IN CHRONIC URTICARIA: A PROSPECTIVE OBSERVATIONAL STUDY IN TERTIARY CARE HOSPITAL

2016 ◽  
Vol 5 (17) ◽  
pp. 822-827
Author(s):  
Rakesh Kumar Patel ◽  
Anil Kumar Gupta ◽  
Santosh Kumar Singh ◽  
Harleen Chhachhi ◽  
Pawan Kumar Patel ◽  
...  
Keyword(s):  
Observational Study ◽  
Chronic Urticaria ◽  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Autologous Serum ◽  
Care Hospital ◽  
Serum Therapy

Epidemiology of nosocomial infections in medicine intensive care unit at a tertiary care hospital in northern India

2008 ◽  
Vol 38 (4) ◽  
pp. 233-235 ◽  
Author(s):  
Shabina Habibi ◽  
Naveet Wig ◽  
Sunil Agarwal ◽  
Surendra K Sharma ◽  
Rakesh Lodha ◽  
...  
Keyword(s):  
Intensive Care ◽  
Nosocomial Infections ◽  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Blood Stream Infection ◽  
Tertiary Care ◽  
Blood Stream ◽  
Care Hospital ◽  
Northern India ◽  
Third Generation Cephalosporins

This prospective observational study describes the rates of nosocomial infections (NI), the sites of infection, the pathogens involved, their antibiogram and the risk factors at a tertiary care hospital in northern India. In 62 of the 182 enrolled patients 95 episodes of NI were recorded (incidence rate 28.6/1000 person days): pneumonia (77%); urinary tract infection (24%) and blood stream infection (24%). All isolates of Acinetobacter, Pseudomonas and Klebsiella and 83.3% of Escherichia coli were resistant to the third generation cephalosporins. An increased duration of the time spent in intensive care units and days of intervention were associated with incident NI.

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