scholarly journals A rare case of invasive fungal sinusitis by co-infection of two fungi in a post COVID-19 patient: a case report

2021 ◽  
Vol 7 (8) ◽  
pp. 1361
Author(s):  
Timna Chungath ◽  
Deepak Dileep Kumar ◽  
Shalu Susan Mathew ◽  
Jijo Paul
Keyword(s):  
Case Report ◽  
Nasal Cavity ◽  
Liposomal Amphotericin ◽  
Rare Case ◽  
Patient Survival ◽  
Severe Headache ◽  
Fungal Sinusitis ◽  
Invasive Fungal Sinusitis ◽  
Fungal Rhinosinusitis ◽  
Invasive Fungal Rhinosinusitis

<p>Invasive fungal rhinosinusitis is a disease of the paranasal sinuses and nasal cavity that typically affects immunocompromised patients in acute fulminant form. Early symptoms can often mimic rhino sinusitis while late symptoms can cause significant morbidity and mortality. With early diagnosis and treatment can increase the patient survival. This case report is of 73 years old diabetic post COVID-19 patients. The patient presented to us was having severe headache and facial pain confined to left side cheek area with loosening of teeth. The patient underwent nasal cavity and biopsy from the maxillary sinus (left side) under local anaesthesia, which confirmed the diagnosis of invasive fungal sinusitis suggestive of co-infection by 2 fungi, aspergillus flavus and mucor. Further, the patient underwent surgical debridement and started on liposomal amphotericin B and patient improved significantly.</p>

scholarly journals Invasive Fungal Rhinosinusitis: Our Experience

2009 ◽  
Vol 2 (3) ◽  
pp. 21-26
Author(s):  
Kapil Dua ◽  
H Chopra ◽  
Neha Chopra ◽  
Sanjeev Puri ◽  
Vikrant Mittal
Keyword(s):  
Facial Pain ◽  
Antifungal Agents ◽  
Fungal Infections ◽  
Immunocompromised Patient ◽  
Fungal Sinusitis ◽  
Adequate Treatment ◽  
Invasive Fungal Sinusitis ◽  
Fungal Rhinosinusitis ◽  
Endemic Mycoses ◽  
Invasive Fungal Rhinosinusitis

Abstract Opportunistic fungal infections in immunocompromised patients are associated with a high mortality rate. Endemic mycoses are often asymptomatic, but in appropriate hosts, fungi can cause severe and even fatal infection. Facial pain in an immunocompromised patient may signify invasive fungal sinusitis. Treatment with antifungal agents needs to be individualized according to factors such as the type of fungus, presence of renal failure, or pregnancy. Combining antifungal agents or addition of other approaches, such as surgical debridement or steps to control intracranial pressure, may be needed for adequate treatment of certain types of fungal infections.

TO DETERMINE THE VARIOUS CLINICAL PRESENTATIONS, UNDERLYING IMMUNOCOMPROMISED CONDITION, COMPLICATION OF ACUTE INVASIVE FUNGAL RHINOSINUSITIS (AIFRS): AN OBSERVATIONAL STUDY.

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Abhiniti . ◽  
Pawan Kumar Lal
Keyword(s):  
Diabetes Mellitus ◽  
Observational Study ◽  
Sinus Thrombosis ◽  
Fungal Sinusitis ◽  
Cavernous Sinus Thrombosis ◽  
Invasive Fungal Sinusitis ◽  
Fungal Rhinosinusitis ◽  
Acute Invasive Fungal Rhinosinusitis ◽  
Clinical Presentations ◽  
Invasive Fungal Rhinosinusitis

Aim: to determine the various clinical presentations, underlying immune-compromised condition, complication of acute invasive fungal rhinosinusitis (AIFRS). Materials and Methods: The present prospective observational study was conducted in the Department of ENT, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar, India. Among 40 patients of acute invasive fungal sinusitis that underwent treatment as inpatient basis. Nasal swabs from the middle meatus were subjected to potassium hydroxide mount and if fungal elements were identified, then fungal culture was done. Post-operatively, tissue removed from the sinuses was sent for histopathological examinations. Results: majority of the patients were male 57.5% and rest 42.5% were female. Patients having Diabetes Mellitus were found to be more susceptible to acute and invasive fungal sinusitis. The common presenting symptoms were nasal obstruction followed by rhinorrhea, epistaxis, headache, fever, facial swelling. Most common complication reported in this study was Cavernous sinus thrombosis 11 (27.5%). Conclusion: acute invasive fungal sinusitis is most common in immunocompromised patients, with the highest incidence in patients with uncontrolled diabetes mellitus. The most consistent finding of acute invasive fungal sinusitis was mucosal necrosis and black crust/debris. Keywords: acute invasive fungal sinusitis, diabetes mellitus, cavernous sinus thrombosis

Invasive Fungal Sinusitis by Lasiodiplodia theobromae in an Patient with Aplastic Anemia: An Extremely Rare Case Report and Literature Review

2016 ◽  
Vol 181 (11-12) ◽  
pp. 901-908 ◽  
Author(s):  
Hyun Jung Gu ◽  
Young Jin Kim ◽  
Hee Joo Lee ◽  
Sung Hwa Dong ◽  
Sung Wan Kim ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Aplastic Anemia ◽  
Rare Case ◽  
Fungal Sinusitis ◽  
Lasiodiplodia Theobromae ◽  
Invasive Fungal Sinusitis ◽  
Rare Case Report

scholarly journals Invasive fungal rhinosinusitis in patients with diabetes

2018 ◽  
Vol 12 (09) ◽  
pp. 787-793
Author(s):  
Nishant Raizada ◽  
Viveka P Jyotsna ◽  
Devasenathipathy Kandasamy ◽  
Immaculata Xess ◽  
Alok Thakar ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Care Center ◽  
Tertiary Care ◽  
North India ◽  
Treatment Modalities ◽  
Fungal Sinusitis ◽  
Invasive Fungal Sinusitis ◽  
Fungal Rhinosinusitis ◽  
Patients With Diabetes ◽  
Invasive Fungal Rhinosinusitis

Introduction: We report the clinical and radiological features as well as outcomes of invasive fungal rhinosinusitis in patients with diabetes from a tertiary care center in North India. Methodology: All patients admitted with a diagnosis of invasive fungal rhinosinusitis with pre-existing or newly diagnosed diabetes from 1st January 2008 to 31st December 2015 were included. Hospital records were used to identify clinical features, biochemical investigations and treatment modalities used. The imaging findings were reported at baseline, 30, 60,90 and 120 days of admission and progression of disease was reported as static, worse or improved. The outcomes were sight loss and survival at end of hospital stay. Results: 22 patients of invasive fungal sinusitis and diabetes were identified. At presentation, 5 had ketoacidosis, all of whom died at the end of hospital stay. Loss of vision in one eye was seen in 70% cases. The survival at end of hospital stay was 72.7% and at six months after end of study period was 57.8%. No patients had radiological improvement at day 30 imaging (including those who subsequently improved). Conclusion: Radiological improvement is not apparent before two months of therapy. Ketoacidosis is a predictor of mortality in invasive fungal sinusitis with diabetes.

scholarly journals Chronic Invasive Fungal Rhinosinusitis in Immunocompetent Patients: A Retrospective Chart Review

2020 ◽  
Vol 7 ◽  
Author(s):  
Naif H. Alotaibi ◽  
Omar Abu Omar ◽  
Mays Altahan ◽  
Haifa Alsheikh ◽  
Fawziah Al Mana ◽  
...  
Keyword(s):  
Chart Review ◽  
Tertiary Care ◽  
Retrospective Chart Review ◽  
Csf Leak ◽  
Fungal Sinusitis ◽  
Invasive Fungal Sinusitis ◽  
Fungal Rhinosinusitis ◽  
Invasive Fungal Rhinosinusitis ◽  
Chronic Invasive ◽  
Immunocompetent Patients

Objective: We report cases of Chronic Invasive Fungal Sinusitis (CIFS) in patients considered as immunocompetent at tertiary care center (King Faisal Specialist Hospital), to analyze their clinical, biological, radiological features, and management.Material and methods: A retrospective chart review of CIFS in immunocompetent patients. The inclusion criteria as the following: immunocompetent patients of any age with histopathological findings of CIFS. Immunocompromised patients, acute Invasive Fungal Sinusitis (IFS), non-invasive fungal rhinosinusitis, and no positive histological findings were excluded.Results: Seventeen (17) patients were included. The species isolated included: Aspergillus (most frequent) &amp; Mucor. Surgical treatment approaches were described. Complications reported include CSF leak, blindness, recurrence, and death.Conclusions: Early diagnosis and management of CIFS improve clinical outcomes.

scholarly journals Allergen Immunotherapy in an HIV+ Patient with Allergic Fungal Rhinosinusitis

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Ian A. Myles ◽  
Satyen Gada
Keyword(s):  
Allergen Immunotherapy ◽  
Severe Infection ◽  
Invasive Fungal Disease ◽  
Fungal Disease ◽  
Fungal Sinusitis ◽  
Opportunistic Pathogens ◽  
Fungal Rhinosinusitis ◽  
Allergic Fungal Rhinosinusitis ◽  
Invasive Fungal Rhinosinusitis ◽  
Chronic Invasive

Patients with HIV/AIDS can present with multiple types of fungal rhinosinusitis, fungal balls, granulomatous invasive fungal rhinosinusitis, acute or chronic invasive fungal rhinosinusitis, or allergic fungal rhinosinusitis (AFRS). Given the variable spectrum of immune status and susceptibility to severe infection from opportunistic pathogens it is extremely important that clinicians distinguish aggressive fungal invasive fungal disease from the much milder forms such as AFRS. Here we describe a patient with HIV and AFRS to both remind providers of the importance of ruling out invasive fungal disease and outline the other unique features of fungal sinusitis treatment in the HIV-positive population. Additionally we discuss the evidence for and against use of allergen immunotherapy (AIT) for fungal disease in general, as well as the evidence for AIT in the HIV population.

Paranasal Sinuses Fungal Balls in Children

2010 ◽  
Vol 3 (3) ◽  
pp. 181-183
Author(s):  
Sunita Agarwal
Keyword(s):  
Case Report ◽  
Young Children ◽  
Ct Scan ◽  
Paranasal Sinuses ◽  
Histopathological Examination ◽  
Fungal Sinusitis ◽  
Provisional Diagnosis ◽  
Invasive Fungal Sinusitis ◽  
First Case ◽  
Rule Out

Abstract Objective Rare cases of fungal balls of paranasal sinuses in children. No case has been reported in young children so far. However, allergic aspergillosis has been reported in young children. Method A case report of 2 cases of fungal balls of paranasal sinuses in children and review of the current literature concerning fungal balls of paranasal sinuses in children are presented. Result 2 cases of fungal balls in paranasal sinuses were diagnosed in children of 9 and 10 years respectively. Both of them presented with nasal obstruction and eye signs provisional diagnosis was based on CT scan findings. FESS was done and fungal balls were subjected to histopathological examination to rule out invasive fungal sinusitis, fungal staining and culture were done which confirmed the diagnosis of Aspergillosis. Conclusion To our knowledge this is the first case report of fungal balls in PNS in children in otolaryngology literature. Both the patients were males with age of 9 and 10 years respectively.

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