scholarly journals Giant cell tumor of the tenosynovial type in the prevertebral space with a cervical approach

2021 ◽  
Vol 8 (1) ◽  
pp. 81
Author(s):  
Daniel A. Rappoport ◽  
Lucas Fuenzalida ◽  
Patricio I. Sepulveda ◽  
Patricio J. Gac
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Surgical Approaches ◽  
Upper Cervical Spine ◽  
Primary Tumors ◽  
Surgical Interventions ◽  
Complex Anatomy ◽  
Upper Cervical ◽  
Anatomy Of The Neck

<p class="abstract">The complex anatomy of the neck makes surgical interventions of cervical neoplasms a very complex process. The aforementioned challenges the surgeon to find a surgical approach with the least morbidity and cosmetic sequelae. This is particularly true in tumoral occupation of the prevertebral space (PVS), most frequently due to the extension of neoplasms from naso and oropharynx; whereas primary tumors of the PVS are extremely rare. There are a number of surgical approaches to access the skull base and the anterior region of the upper cervical spine, such as the transcervical-transtemporal approach, retraction and dissection of the soft palate, mandibular osteotomy, medial glossotomy, among others. The following article presents a case report in which a less invasive combined transcervical-transoral approach was performed on a tenosynovial giant cell tumor of the PVS. As an alternative in the treatment of these type of lesions, it is in our opinion equally effective and less morbid.</p>

Giant-Cell Tumor of the Tendon Sheath in the Upper Cervical Spine

2012 ◽  
Vol 30 (26) ◽  
pp. e250-e253 ◽  
Author(s):  
William Gemio Jacobsen Teixeira ◽  
Nilton Alves Lara ◽  
Douglas Kenji Narazaki ◽  
Cláudia de Oliveira ◽  
Conrado Cavalcanti ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tendon Sheath ◽  
Cell Tumor ◽  
Upper Cervical Spine ◽  
Upper Cervical

scholarly journals Pediatric Upper Cervical Spine Giant Cell Tumor: Case Report

2014 ◽  
Vol 5 (4) ◽  
pp. 28-33 ◽  
Author(s):  
Mohammad D. Alfawareh ◽  
Irfanullah D. Shah ◽  
Tamer I. Orief ◽  
Mohammad M. Halawani ◽  
Walid I. Attia ◽  
...  
Keyword(s):  
Case Report ◽  
Cervical Spine ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Upper Cervical Spine ◽  
Upper Cervical

scholarly journals Clinical effects of three surgical approaches for a giant cell tumor of the distal radius and ulna

2016 ◽  
Vol 5 (5) ◽  
pp. 613-617 ◽  
Author(s):  
Jing Zhang ◽  
Yi Li ◽  
Dongqi Li ◽  
Junfeng Xia ◽  
Su Li ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Distal Radius ◽  
Cell Tumor ◽  
Surgical Approaches ◽  
Clinical Effects

scholarly journals Giant cell tumor of the spine: A review of 9 surgical interventions in 6 cases

2007 ◽  
Vol 41 (2) ◽  
pp. 146 ◽  
Author(s):  
Abhay Nene ◽  
Sheetal Mohite ◽  
Raghuprasad Varma ◽  
ShekharY Bhojraj
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Surgical Interventions

scholarly journals Giant cell tumor of bone: Unusual features of a rare tumor

Rare Tumors ◽  
2019 ◽  
Vol 11 ◽  
pp. 203636131987889 ◽  
Author(s):  
Ziyad M Mohaidat ◽  
Hisham Z Al-jamal ◽  
Audai M Bany-Khalaf ◽  
Ahmad M Radaideh ◽  
Ziad A Audat
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Malignant Transformation ◽  
Fatal Outcome ◽  
Cell Tumor ◽  
Anatomical Location ◽  
Histopathological Diagnosis ◽  
Intralesional Curettage ◽  
Primary Tumors

Giant cell tumor of bone is a benign tumor with an aggressive behavior. Its typical subarticular location and high recurrence risk can be associated with significant morbidity. Although benign, it can rarely metastasize especially to the lungs. Also, it can be multicentric in less than 1% of patients. Late malignant transformation, although rare, can occur with a very poor prognosis. This series reports on these unusual and challenging features and management considerations of giant cell tumor of bone. This retrospective study included review of the medical records of patients with a confirmed histopathological diagnosis of giant cell tumor of bone. A total of 25 patients (16 females and 9 males) with a mean age of 34.5 years were included; 22 had primary tumors, while 3 were referred with recurrent tumors. Pain was the most common presenting symptom. Most patients had grade III tumors. Tumors around the knee were the most common. Multicentric tumors were detected in three patients. Twenty-three patients (20 primary giant cell tumor of bone and 3 with recurrence) received treatment. Most patients (15/23) were treated with intralesional curettage with or without adjuvants. Seven patients had wide excision. Recurrence was seen in 45% (9/20) of primary giant cell tumor of bone especially with difficult anatomical locations. Most recurrences occurred more than 4 years after treatment. Pulmonary nodules were detected in four patients; two of them showed resolution during follow-up. One patient developed secondary sarcoma transformation with a fatal outcome. Giant cell tumor of bone was more common in females. Long bones were more affected, especially around the knee. Intralesional curettage was the most frequently used treatment. Recurrence was associated with inadequate tumor resection (especially in difficult anatomical location), younger age, male gender, and advanced local tumor grade. Denosumab can be used in the treatment of pulmonary metastasis, multicentric and recurrent giant cell tumor of bone. Due to late recurrence and malignant transformation, a prolonged follow-up is warranted.

scholarly journals Giant cell tumor of patella: A case report and review of literature

2019 ◽  
Vol 6 (1) ◽  
pp. 47-49
Author(s):  
Mohit Kumar Arora ◽  
Ela Madaan ◽  
Rajnand Kumar
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Knee Pain ◽  
Anterior Knee Pain ◽  
Cell Tumor ◽  
Extensor Mechanism ◽  
Benign Tumors ◽  
Primary Tumors ◽  
Anterior Knee

Objective: Patella is a sesamoid bone which develops in the quadriceps tendon. It is an uncommon site for neoplasms. The most common primary tumors which involve patella are benign. These include chondroblastoma, giant cell tumor (GCT) and aneurysmal bone cyst. Malignant lesions are less common in patella. These encompass metastasis, osteosarcoma and hemangioendothelioma. The most common complaint in patients of GCT patella is anterior knee pain. Early diagnosis and optimal management are necessary for improving survival rate in these patients. Case Presentation: The authors present a case report of GCT of patella in a 16-year old child. Incisional biopsy was done to confirm the diagnosis. Further radiological examination showed that the tumor involved almost whole of the patella. Hence, surgical management in the form of patellectomy and extensor mechanism repair was done to improve the outcome of the disease. The patient did not have any clinical or radiological symptoms at the end of the final follow up of 22 months. Conclusion: Primary tumor of patella is a rare entity. Benign tumors like GCT present only with anterior knee pain and should be included in the differential diagnosis of anterior knee pain. MRI is useful to determine the extent of involvement of tumor in the patella. Treatment may vary from curettage and bone grafting to total patellectomy with extensor mechanism repair

scholarly journals Giant Cell Tumor of Lower End of Tibia

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Monish Bami ◽  
Ashok R. Nayak ◽  
Shreepad Kulkarni ◽  
Avinash Kulkarni ◽  
Rupali Gupta
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Ankle Joint ◽  
Mononuclear Cells ◽  
Full Range ◽  
Cell Tumor ◽  
Lytic Lesion ◽  
Primary Tumors ◽  
Vesicular Nucleus ◽  
Left Ankle

Introduction. Giant cell tumor of bones is an unusual neoplasm that accounts for 4% of all primary tumors of bone, and it represents about 10% of malignant primary bone tumors with its different grades from borderline to high grade malignancy.Case Report. A 35-year-old patient presented with complains of pain and swelling in left ankle since 1 year following a twisting injury to his left ankle. On examination, swelling was present over the distal and anterior part of leg and movements of ankle joint were normal. All routine blood investigations were normal. X-ray and CT ankle showed morphology of subarticular well-defined expansile lytic lesion in lower end of left tibia suggestive of giant cell tumor. Histopathology of the tissue shows multinucleated giant cells with uniform vesicular nucleus and mononuclear cells which are spindle shaped with uniform vesicular nucleus suggestive of GCT. The patient was treated by excision, curettage, and bone cement to fill the defect.Conclusion. The patient at 12-month followup is doing well and walking without any pain comfortably and with full range of motion at ankle joint with articular congruity maintained and no signs of recurrences.

scholarly journals Giant cell tumor distal end radius: resection and reconstruction using proximal fibular graft

2021 ◽  
Vol 7 (2) ◽  
pp. 409
Author(s):  
Rahul Bharadwaj ◽  
Vipin Sharma ◽  
Narinder Singh ◽  
Narinder Singh
Keyword(s):  
Range Of Motion ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Giant Cell Tumour ◽  
Wrist Joint ◽  
Cell Tumor ◽  
Fibular Graft ◽  
Primary Tumors ◽  
One Year

<p>Giant cell tumour forms 4% of all primary tumors. GCT distal radius is very rare. Current study presents a case of a 27 year female who was managed by wide excision and reconstruction with ipsilateral fibula. At one year follow up, patient had excellent range of motion at wrist joint and hand.</p>

scholarly journals Surgical management of giant cell tumor of axis vertebra: review of fourteen cases in literature with a case illustration

2017 ◽  
Vol 31 (3) ◽  
pp. 404-413
Author(s):  
Guru Dutta Satyarthee ◽  
Luis Rafael Moscote-Salazar ◽  
Amit Agrawal
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Surgical Resection ◽  
Surgical Management ◽  
Surgical Intervention ◽  
Cell Tumor ◽  
Treatment Modalities ◽  
Surgical Approaches ◽  
Posterior Fixation ◽  
Axis Vertebra

Abstract Primary spinal giant cell tumor (PSGCT) considered as rare primary neoplasm, with predilection for subarticular location and commonly located at knee joint region, sacrum or distal radius, however, spinal involvent is uncommon and comparatively much rarer in the cervical spine. Further occurrence of giant cell tumor in the Axis vertebra is extremely uncommon and easily misdiagnosed and, thus, treatment is still debated and various treatment modalities and different surgical approaches were utilized during evolution of surgical management. Authors could collect only 14 cases of primary giant cell tumor affecting Axis vertebra in a detailed Pubmed and Medline search, out of which 12 cases were primary and rest two case was recurrent. So authors reviewed in total thirteen cases primary giant cell tumor of Axis managed surgically, including our case. Out of 13 PSGCT, twelve cases were managed with surgical resection and the rest one case was managed with monoclonal antibody using Denosomab monotherapy without any surgical intervention. In the surgical group (n=12), nine cases had two staged surgical procedure, first being posterior fixation followed by anterior approach with resection of tumor while, the rest three had one stage surgical resection including current case. Authors reports a unique case of spinal giant cell tumor developing in a- 38 - year male with history of renal transplant, presented with neck pain and difficulty in walking, neuroimaging revealed a osteolytic mass lesion involving body of axis vertebra with extension into right sided lamina, underwent two stage complete surgical intervention. Authors describes management of such rare locally recurring primary bony pathology affecting axis vertebra as it is not only interesting and challenging and different management modalities, various, surgical approaches and issue of renal osteodystrophy along with pertinent literature is also reviewed briefly.

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