scholarly journals Four sexually transmitted diseases in one: a rare case report

2020 ◽  
Vol 6 (2) ◽  
pp. 272
Author(s):  
S. D. Fernandes ◽  
N. Jegadish ◽  
R. Ramachandran ◽  
K. Gopalakrishnan ◽  
Murali Narasimhan
Keyword(s):  
Sexually Transmitted Diseases ◽  
Diagnostic Testing ◽  
Diagnostic Challenge ◽  
Diagnostic Laboratory ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease ◽  
Rare Case Report ◽  
Appropriate Therapy ◽  
Diagnostic Laboratory Tests

<p class="abstract">Sexually transmitted diseases (STDs) often pose a diagnostic challenge especially in countries like India, where access to reliable diagnostic laboratory tests is minimal. The exact cause of the STDs has to be determined, so that appropriate therapy can be administered and the risk of transmission to others can be reduced. However, determining the etiology can be complicated by limitations of current diagnostic testing modalities and by the fact that more than one infection may coexist. Here, authors report a case who presented with genital ulcer disease and discharge with four etiologies.</p>

Etiology of Genital Ulcer Disease in Male Patients Attending a Sexually Transmitted Diseases Clinic

2016 ◽  
Vol 43 (8) ◽  
pp. 494-497 ◽  
Author(s):  
Angel A. Noda ◽  
Orestes Blanco ◽  
Consuelo Correa ◽  
Lissette Pérez ◽  
Vivian Kourí ◽  
...  
Keyword(s):  
Sexually Transmitted Diseases ◽  
Genital Ulcer ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease ◽  
Male Patients

Sexually Transmitted Diseases

2012 ◽  
pp. 360-374
Author(s):  
Randall S. Edson
Keyword(s):  
Herpes Simplex ◽  
Sexually Transmitted Diseases ◽  
Public Health Problem ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease ◽  
Significant Public Health Problem ◽  
Significant Public Health ◽  
Control And Prevention ◽  
Simplex Virus

Sexually transmitted diseases (STDs) are a significant public health problem. The Centers for Disease Control and Prevention estimates that approximately 19 million new cases of STDs occur annually. Approximately half of all STDs occur in persons aged 15 to 24 years. Figures are clearly an underestimate of the true burden of STDs. Many cases are not diagnosed. Infections due to herpes simplex virus (HSV) and human papillomavirus are not reportable. Diagnosis and treatment of genital ulcer disease, syphilis, herpes simplex, canchroid, urethritits, gonorrhea, HPV, chlamydia, and other less-common sexually transmitted diseases are reviewed.

Etiology of Genital Ulcer Disease in Dakar, Senegal, and Comparison of PCR and Serologic Assays for Detection of Haemophilus ducreyi

2000 ◽  
Vol 38 (1) ◽  
pp. 268-273
Author(s):  
Patricia A. Totten ◽  
Jane M. Kuypers ◽  
Cheng-Yen Chen ◽  
Michelle J. Alfa ◽  
Linda M. Parsons ◽  
...  
Keyword(s):  
Transmitted Disease ◽  
Haemophilus Ducreyi ◽  
Genital Ulcer ◽  
Serological Tests ◽  
Past Infection ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease ◽  
Pcr Assays ◽  
Simplex Virus

ABSTRACT We used PCR assays to determine the etiology of genital ulcers in patients presenting to a sexually transmitted disease clinic in Dakar, Senegal, and evaluated the ability of two PCR tests ( groEL and recD ) and two serological tests (adsorption enzyme immunoassay [EIA] and lipooligosaccharide [LOS] EIA) to detect current Haemophilus ducreyi infection. We found that in this population, H. ducreyi , T. pallidum , and herpes simplex virus HSV DNA were detected in 56, 15, and 13% of 39 genital ulcer specimens, respectively, and H. ducreyi DNA was detected in 60% (3 of 5) of samples from ulcerated bubos. Among 40 consecutive patients with genital ulcer disease and with sufficient sample for both PCR assays, the recD and groEL H. ducreyi PCR assays were 83% concordant, with the recD PCR assay detecting six (15%) additional positive specimens and the groEL assay detecting one (3%) additional positive specimen. Compared to PCR, the adsorption EIA and LOS EIA tests had sensitivities of 71 and 59% and specificities of 57 and 90%, respectively, for the diagnosis of current H. ducreyi infection. While these differences in specificity could be due either to previous infection with H. ducreyi or to the detection of cross-reacting antibodies, only 6% of patients from a nearby family planning clinic gave a positive reaction in both the adsorption EIA and LOS EIA assays, indicating that cross-reacting antibodies are not prevalent among clinic attendees in this city. Our studies indicate that the adsorption EIA detects both current and past infection, while the LOS EIA assay is more specific for current infection with H. ducreyi in this population.

scholarly journals The Laboratory Diagnosis ofHaemophilus ducreyi

2005 ◽  
Vol 16 (1) ◽  
pp. 31-34 ◽  
Author(s):  
Michelle Alfa
Keyword(s):  
Diagnostic Testing ◽  
Laboratory Diagnosis ◽  
Primary Method ◽  
Sample Collection ◽  
Culture Methods ◽  
Transmitted Infection ◽  
Diagnostic Laboratory ◽  
Sexually Transmitted ◽  
Alternative Approaches ◽  
Genetic Amplification

Chancroid is a sexually transmitted infection caused byHaemophilus ducreyi. This fastidious, Gram-negative coccobacilli dies rapidly outside the human host, making diagnostic testing using culture methods difficult. This genital ulcer infection is not common in Canada and, therefore, can often be misdiagnosed. The objective of the present paper is to provide practical approaches for the diagnosis of chancroid in Canadian patients where the prevalence of this infection is low. Issues related to sample collection, sample transport and available diagnostic tests are reviewed, and several alternative approaches are outlined. Although antigen detection, serology and genetic amplification methods have all been reported forH ducreyi, none are commercially available. Culture is still the primary method available to most laboratories. However, the special media necessary for direct bedside inoculation is often not available; therefore, communication with the diagnostic laboratory and rapid specimen transport are essential when chancroid is suspected

Genital ulceration

2020 ◽  
pp. 1610-1612
Author(s):  
Patrick French ◽  
Raj Patel
Keyword(s):  
Risk Factor ◽  
Sexually Transmitted Infections ◽  
Diagnostic Tests ◽  
Major Risk Factor ◽  
Travel History ◽  
Genital Ulceration ◽  
Specific Diagnosis ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease

Genital ulceration can be caused by many common and rare sexually transmitted infections (STIs), dermatological conditions, and trauma. Key to making a specific diagnosis that will direct treatment is a standard sexual and travel history followed by appropriate diagnostic tests. Genital ulcer disease is a major risk factor for the acquisition and transmission of HIV. Various classifications and algorithms are proposed to help identify pathogens and guide immediate management, but care must be taken when working through these.

THE ETIOLOGY OF GENITAL ULCER DISEASE AND ITS RELATIONSHIP TO HIV INFECTION IN INDIAN SEXUALLY TRANSMITTED DISEASE CLINICS

1995 ◽  
Vol 88 ◽  
pp. S55
Author(s):  
Arun Risbud ◽  
Kirk Chan-Tack ◽  
Robert Bollinger ◽  
Sanjay Mehendale ◽  
Deepak Gadkari ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Sexually Transmitted Disease ◽  
Transmitted Disease ◽  
Genital Ulcer ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease
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