TRICHOMONAS VAGINALIS E ANORMALIDES CITOPATÓLOGICAS NOS EXAMES CITOPATOLÓGICOS REALIZADOS EM UM LABORATÓRIO CLÍNICO DA PONTIFÍCIA UNIVERSIDADE CATÓLICA DE GOIÁS - GO: ESTUDO DE PREVALÊNCIA

2020 ◽  
Vol 47 (1) ◽  
pp. 6104
Author(s):  
Andrea Alves Ribeiro ◽  
Sara Rosa Peixoto ◽  
Gabriel Henrique Martins de Almeida Araújo ◽  
Carolina Tonello dos Santos Pelá Alcanfor

O Trichomonas vaginalis é um protozoário que causa uma das principais infecções sexualmente transmissíveis. O objetivo foi estimar a prevalência de Trichomonas vaginalis em um Laboratório escola de Goiânia-GO. É um estudo retrospectivo utilizando as fichas de requisição dos exames citopatológicos realizados no Laboratório Clínico da Pontifícia Universidade Católica de Goiás (LC-PUCGO) entre janeiro de 2013 a dezembro de 2015. As variáveis foram categorizadas no programa Excel 2013 e tabulados no programa Epi Info™ versão 7, para avaliação da associação entre as variáveis foi realizado o cálculo do Odds Ratio (OR), considerando um intervalo de confiança (IC) de 95% e o valor de significância p< 0,05. Do total dos 4558 exames citopatológicos satisfatórios foi encontrada uma prevalência de Lactobacillus sp., de 46,97% (2141/4558) seguida por bacilos 24,62% (1122/4558), bacilos e cocos de 21,68% (988/4558), cocos de 3,86%(176/4558) e bacilos e lactobacilos de 2,87% (131/4558). Os agentes patogênicos encontrados foram Gardnerella vaginalis 79,6% (1141/1433), Candida sp. 17,7% (253/1433), Trichomonas vaginalis de 2,2% (32/1433), Herpes simplex de 0,4% (6/1433) e Chlamydia trachomatis de 0,1% (1/1433). Dentre os 4558 exames citopatológicos, 14,39% (656/4558) apresentaram anormalidades citológicas. As anormalidades encontradas foram ASC-US 2,57% (117/656), LSIL 1,78 % (81/656), ASC-H 3,52 % (160/656), HSIL 1,08% (48/656), AGC NEO 0,22% (10/656), Carcinoma invasor 0,02 % (1/656). Houve uma associação estatisticamente significante com a presença de Trichomonas vaginalis e o padrão anaeróbio OR 44,89 (IC 95 %: 10.5-271,8 p < 0,000). A detecção da manifestação por Trichomonas vaginalis é bastante sensível por meio do exame citopatológico. A presença de Trichomonas vaginalis, em um percentual relativamente baixo, indica a necessidade de identificação dos fatores de risco e aconselhamento em relação à proteção, transmissão e tratamento dessa infecção.

1991 ◽  
Vol 42 (3) ◽  
pp. 223-226
Author(s):  
Clara Inés Vargas ◽  
Betty Lucy Galindo ◽  
Jorge Enrique Martinez

Con el fin de determinar los patógenos vaginales y cervicales, y su relación con los métodos de planificación, estudiamos a una población de 300 mujeres que planificaban con anovulatorios o dispositivos intrauterinos y las comparamos con un grupo de 144 mujeres que utilizaban métodos naturales o de barrera para su control natal. Al analizar los resultados observamos que el patógeno más comúnmente aislado de la vagina de las pacientes de los diferentes grupos fue la Gardnerella vaginalis [38. 7% ). que la Candida sp no se presentó con mayor frecuencia en el grupo de mujeres que planificaban con anovulatorios [9%, control 11% ). y que la frecuencia de aislamiento de la Chlamydia trachomatis del cervix de las mujeres que planificaban fue en aumento a través del estudio [muestra 1: 4.6%; muestra 4: 20.9%), no así el grupo control [muestra 1: 11%; muestra 4 : 12%). [Rev Col Obstet Ginecol 1991; 42[3): 223-226).


Mycoses ◽  
2002 ◽  
Vol 45 (S2) ◽  
pp. 24-24
Author(s):  
U.-C. Hipler ◽  
C. Greif ◽  
U. Metzner ◽  
C. Hipler ◽  
P. Elsner

1995 ◽  
Vol 113 (6) ◽  
pp. 1009-1011 ◽  
Author(s):  
Edenilson Eduardo Galore ◽  
Maria José Cavaliere ◽  
Neuza Kasumi Shirata ◽  
Maria de Fátima Araújo

It has been described that women infected with the human immunodeffciency virus (HIV) present more frequent cytological abnormalities in cervicovaginal smears, generally related to infection by human papillomavirus (HPV). The present work is a study of cervicovaginal smears of 147 HIV-seropositive women submitted to routine gynecological examinations. The smears were stained by the Papanicolaou method. Cytopathic effects of HPV were found in 38 (25.8%) cases. Nuclear atypias of cervical intraepithelial neoplasia (CIN) were evident in 36 (24.5%) of these cases: 27 (18.4%), CIN I; 6 (4.0%), CIN II and 3 (2.0%) CIN III. Also 2 (1.4%) invasive carcinomas and one (0.7%) endocervical dysplasia were found. Other agents observed were: Candida sp, 19 (12.9%) cases, Gardnerella vaginalis, 19 (12.9%), Trichomonas vaginalis, 13 (8.4%), Chlamydia trachomatis 5 (3.4%), Mobiluncus sp 2 (1.4%) and Herpes simplex virus 1 (0.7%). This study emphasizes the high frequency of HPV/CIN cervicovaginal abnormalities in HIV-seropositive in our population. It is possible that immunological factors and sexual promiscuity are involved in this phenomenon.


1998 ◽  
Vol 9 (6) ◽  
pp. 350-353 ◽  
Author(s):  
Iwona Ostaszewska ◽  
Bozena Zdrodowska-Stefanow ◽  
Jerzy Badyda ◽  
Katarzyna Pucilo ◽  
Jadwiga Trybula ◽  
...  

Summary: Seventy-eight men with symptoms of chronic or subacute prostatitis were enrolled. Investigations for the presence of Chlamydia trachomatis in urethral swabs were carried out. The expressed prostatic secretions were additionally examined for Mycoplasma hominis , Ureaplasma urealyticum , Gardnerella vaginalis , other Gram-negative and Gram-positive bacteria, Trichomonas vaginalis , yeast-like fungi and leucocyte count. Furthermore, all patients were evaluated for the presence of serum anti-chlamydial IgG antibodies. Signs of inflammation on the basis of the count of leucocytes per hpf in the prostatic secretions were detected in 42 patients (group I). Prostatodynia was found in the remaining 36 men (group II). In group I, chlamydial antigen was detected in the urethra and expressed prostatic secretions (EPS) in 6 (14.3%) and 9 (21.4%) patients, respectively. No evidence of current chlamydial infection was found in group II. The presence of serum anti-chlamydial IgG antibodies was demonstrated in 13/42 (30.9%) patients with prostatitis and in 3/36 (8.3%) patients with prostatodynia ( P 0.01). The results suggest that chlamydia may be one of the causative agents of chronic prostatitis. <


2021 ◽  
Author(s):  
Elizabeth Okecha ◽  
Emily Boardman ◽  
Saleha Patel ◽  
Emile Morgan

AbstractBackgroundOnline pharmacies offer an alternative approach for patients to manage their sexual health. Our aim was to determine the type of antimicrobials sold as treatment for sexually transmitted infections (STIs) by UK internet pharmacies and if providers were adhering to national guidelines.MethodsA search engine results page (SERP) generated a list of registered UK online pharmacies offering treatment for the following infections: Chlamydia trachomatis, Neisseria gonorrhoeae, Herpes simplex and Trichomonas vaginalis. An initial audit in 2017 benchmarked each provider against the British Association of Sexual Health & HIV (BASHH guidelines. Results were fed back to each provider before re-audit in 2020. Websites selling antibiotics for non-gonococcal urethritis (NGU) and Mycoplasma genitalium were included at re-audit.ResultsThere were 30 pharmacies identified in 2017 of which, five were excluded. Treatment could be obtained for Neisseria gonorrhoeae from five pharmacies without providing a culture result; three (60%) pharmacies sold BASHH approved antibiotics for Neisseria gonorrhoeae. All 25 pharmacies sold Chlamydia trachomatis treatment; 22 (88%) offered first line treatment options but no website assessed for proctitis. Herpes simplex treatment was sold on 22 websites of which, 13 (59%) offered treatment recommended by BASHH. Trichomonas vaginalis treatment was sold by four websites in line with BASHH. Results at re-audit showed an improvement in standards, although advice before, during and after treatment remained variable.DiscussionOur work has allowed us to engage with providers to improve prescribing within the UK online pharmacy industry. However, tougher regulation is needed in order to embed sustainable change for patients who choose to access treatment online.


2020 ◽  
Vol 11 (3) ◽  
Author(s):  
Nathanael De Souza Maciel ◽  
Francisco Jardsom Moura Luzia ◽  
Diego Da Silva Ferreira ◽  
Maria Charlianne de Lima Pereira Silva ◽  
Davide Carlos Joaquim ◽  
...  

Objetivo: Analisar os resultados do último laudo citopatológico de pacientes com o exame Papanicolaou em atraso. Metodologia: Estudo documental, retrospectivo, com abordagem quantitativa, realizado no município de Redenção–CE. Foram explorados 660 prontuários de mulheres com idade entre 25 e 64 anos. Para análise foram utilizadas medidas de tendência central e frequências absolutas e relativas. Resultados: O número de mulheres que nunca haviam realizado o exame Papanicolaou foi de 44,7% e as que haviam realizado, mas estavam em atraso, foi de 55,3%. A presença de células metaplásicas foi menos frequente (38,6%). Entre agentes infecciosos, houve prevalência dos resultados sugestivos de Gardnerella vaginalis e Mobiluncus (14,9%), Cândida sp (3,9%) e Trichomonas vaginalis (1,1%).  Os laudos indicaram presença de alterações celulares pré-malignas e malignas. Conclusão: Esta análise poderá motivar a implementação da busca de pacientes com exame atrasado, especialmente das que apresentam alguma infecção sexualmente transmissível ou alteração celular pré-maligna ou maligna.Descritores: Neoplasias do Colo do Útero; Teste de Papanicolaou; Programas de Rastreamento; Atenção Primária à Saúde, Enfermagem.ANALYSIS OF THE RESULTS OF THE LAST CYTOPATHOLOGICAL EXAM OF PATIENTS WITH DELAYED PAP SMEARObjective: To analyze the results of the last cytopathological report of patients with delayed Pap smear. Methodology: Documentary, retrospective study with quantitative approach, conducted in the city of Redenção-CE, from April to September 2018. Were explored 660 medical records of women aged 25 to 64 years. For analysis, measures of central tendency and absolute and relative frequencies were used. Results: The number of women who had never had the Pap smear was 44,7%, and those who had been submitted but were delayed were 55,3%. The presence of metaplastic cells was less frequent (38,6%). Among infectious agents, there was a prevalence of suggestive results of Gardnerella vaginalis and Mobiluncus (14,9%), Candida sp (3,9%) and Trichomonas vaginalis (1,1%). The reports indicated the presence of premalignant and malignant cellular alterations. Conclusion: There are a large number of women with delayed Pap tests and a deficiency in the quality of the tests, indicated by the absence of metaplastic tissue. This should motivate the active search of patients to interrupt the chain of transmission of Sexually Transmitted Infections and to treat cervical lesions early, reducing the chances of progression.KEYWORDS: Uterine Cervical Neoplasms, Papanicolaou Test, Mass Screening, Primary Health Care, Nursing. ANÁLISIS DE LOS RESULTADOS DEL ÚLTIMO EXAMEN CITOPATOLÓGICO DE PACIENTES CON PAPANICOLAOU EN RETRASOObjetivo: Analizar resultados del último examen citopatológico de pacientes con Papanicolaou en retraso. Metodología: Estudio documental, retrospectivo, con enfoque cuantitativo, realizado en la ciudad de Redenção-CE, de abril a septiembre de 2018. Fueron explorados 660 prontuarios de mujeres de 25 a 64 años. Para el análisis, se utilizaron medidas de tendencia central, frecuencias absolutas y relativas. Resultados: El número de mujeres que nunca se habían hecho la prueba de Papanicolaou fue del 44,7%, y las que se sometieron, pero estában en retraso, fueron 55,3%. La presencia de células metaplásicas fue menos frecuente (38,6%). Entre los agentes infecciosos, hubo una prevalencia de resultados sugestivos de Gardnerella vaginalis y Mobiluncus (14,9%), Candida sp (3,9%) y Trichomonas vaginalis (1,1%). Los informes indicaron presencia de alteraciones celulares premalignas y malignas. Conclusión: Hoy una gran cantidad de mujeres con pruebas de Papanicolaou retrasadas y una deficiencia en la calidad de los exámenes, indicada por la ausencia de tejido metaplásico. Esto debería motivar la búsqueda activa de pacientes para interrumpir la cadena de transmisión de las infecciones de transmisión sexual y para tratar las lesiones cervicales temprano, reduciendo las posibilidades de progresión.PALABRAS-CLAVE: Neoplasias del Cuello Uterino, Prueba de Papanicolaou, Tamizaje Masivo, Atención Primaria de Salud, Enfermería.


2021 ◽  
Vol 9 (9) ◽  
pp. 1864
Author(s):  
Shu-Fang Chiu ◽  
Po-Jung Huang ◽  
Wei-Hung Cheng ◽  
Ching-Yun Huang ◽  
Lichieh Julie Chu ◽  
...  

The three most common sexually transmitted infections (STIs) are Chlamydia trachomatis (CT), Neisseria gonorrhoeae (GC) and Trichomonas vaginalis (TV). The prevalence of these STIs in Taiwan remains largely unknown and the risk of STI acquisition affected by the vaginal microbiota is also elusive. In this study, a total of 327 vaginal swabs collected from women with vaginitis were analyzed to determine the presence of STIs and the associated microorganisms by using the BD Max CT/GC/TV molecular assay, microbial cultures, and 16S rRNA sequencing. The prevalence of CT, TV, and GC was 10.8%, 2.2% and 0.6%, respectively. A culture-dependent method identified that Escherichia coli and Streptococcus agalactiae (GBS) were more likely to be associated with CT and TV infections. In CT-positive patients, the vaginal microbiota was dominated by L. iners, and the relative abundance of Gardnerella vaginalis (12.46%) was also higher than that in TV-positive patients and the non-STIs group. However, Lactobacillus spp. was significantly lower in TV-positive patients, while GBS (10.11%), Prevotella bivia (6.19%), Sneathia sanguinegens (12.75%), and Gemella asaccharolytica (5.31%) were significantly enriched. Using an in vitro co-culture assay, we demonstrated that the growth of L. iners was suppressed in the initial interaction with TV, but it may adapt and survive after longer exposure to TV. Additionally, it is noteworthy that TV was able to promote GBS growth. Our study highlights the vaginal microbiota composition associated with the common STIs and the crosstalk between TV and the associated bacteria, paving the way for future development of health interventions targeting the specific vaginal bacterial taxa to reduce the risk of common STIs.


2012 ◽  
Vol 17 (4) ◽  
Author(s):  
Ana Paula Vieira Bringel ◽  
Marina Pessoa de Farias Rodrigues ◽  
Eglídia Carla Figueirêdo Vidal

Estudo descritivo teve por objetivo caracterizar os aspectos microbiológicos e epiteliais presentes nos exames preventivos realizados em uma unidade básica de saúde de Juazeiro do Norte - Ceará. Os dados foram coletados de julho a novembro de 2011, mediante a análise de 782 resultados de Papanicolaou realizados entre março de 2008 e outubro de 2011 e que constavam no livro de registros de preventivos da unidade. Os dados foram analisados com auxílio do programa estatístico SPSS 16.0. Os resultados evidenciaram maior procura de mulheres entre 25 a 34 anos (28,4%) para a realização do exame; no esfregaço houve prevalência de epitélio escamoso (80,9%), Cocos (49,2%) e agentes infecciosos como Gardnerella vaginalis (65%), Cândida sp (23,7%) e Trichomonas vaginalis (5,6%). O profissional de saúde precisa identificar os fatores de risco associados às afecções, possibilitando prevenção do câncer do colo uterino e controle das Doenças Sexualmente Transmissíveis.


Sign in / Sign up

Export Citation Format

Share Document