scholarly journals Clinical characteristics of progressive nonarteritic anterior ischemic optic neuropathy

2021 ◽  
Vol 14 (4) ◽  
pp. 517-522
Author(s):  
Omer Y. Bialer ◽  
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Color Vision ◽  
Symptom Onset ◽  
Systemic Risk ◽  
Clinical Characteristics ◽  
Visual Outcome ◽  
Ischemic Optic Neuropathy ◽  
Systemic Risk Factors

AIM: To study whether patients with progressive nonarteritic anterior ischemic optic neuropathy (NAION) present earlier than patients with stable NAION and to describe their clinical characteristics and visual outcome. METHODS: This was a retrospective chart review. All patients with NAION seen during the acute stage from January 2012 to December 2018 were reviewed. Patients were included if they had documented disc edema and follow up of at least 3mo. Patients with progressive NAION were identified if they worsened in 2 out of 3 parameters: visual acuity ≥3 Snellen lines; Color vision ≥4 Ishihara plates; the visual field defect involved a new quadrant. The clinical characteristics, time from symptom onset to presentation, systemic risk factors and visual outcome were compared to patients with stable NAION. RESULTS: Totally 122 NAION cases met the inclusion criteria. Mean age was 58.1y (range 22-74), 70% were men. Twenty cases (16.4%) had progressive NAION. Patients with progressive NAION did not differ from stable NAION in their demographics, systemic risk factors or in their initial visual deficit. At last follow up, median visual acuity was 1.0 logMAR (IQR 0.64-1.55) in patients with progressive NAION, vs 0.18 (IQR 0.1-0.63) in stable NAION (P<0.001). Median color vision testing was 0 plates correct (IQR 0-2.5%) vs 92% plates correct (IQR 50%-100%) in the stable NAION group (P<0.001). Patients with progressive NAION differed in the time from symptom onset to presentation (median 2d vs 5d, P=0.011). CONCLUSION: We find no identifiable risk factors associated with progressive NAION. Progressors arrive earlier for ophthalmological evaluation.

Bilateral Ischemic Optic Neuropathy Following Intravenous Immunoglobulin

2019 ◽  
Vol 3 (2) ◽  
pp. 111-113
Author(s):  
Waseem H. Ansari ◽  
Brittany K. Patrick ◽  
Bradley T. Smith
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Intravenous Immunoglobulin ◽  
Optic Neuropathy ◽  
Temporal Relationship ◽  
Ischemic Optic Neuropathy ◽  
Ivig Infusion ◽  
Minimal Improvement ◽  
Contralateral Eye

Purpose: The purpose of this work is to report an association between intravenous immunoglobulin (IVIG) infusions and the development of bilateral ischemic optic neuropathy. Methods: A case report is described. Results: A 76-year-old male receiving IVIG infusions developed loss of vision in the left eye and was diagnosed with ischemic optic neuropathy. Two months later, he developed another episode of ischemic optic neuropathy in the contralateral eye. The investigation for giant-cell arteritis, vasculopathy, and infiltrative processes was negative. The patient had minimal improvement in visual acuity over several months of follow-up. Conclusions: Bilateral ischemic optic neuropathy was likely caused by IVIG infusion in this case, given the temporal relationship and the negative workup for other risk factors.

CLINICAL PROFILE, RISK FACTORS AND VISUAL OUTCOME IN PATIENTS OF ACUTE CENTRAL SEROUS CHORIORETINOPATHY IN A TERTIARY HEALTH CARE CENTRE IN NORTHERN INDIA.

2021 ◽  
pp. 67-69
Author(s):  
Upasna Ajmani ◽  
Prempal Kaur ◽  
Dinesh Kumar
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Color Vision ◽  
Central Serous Chorioretinopathy ◽  
Visual Outcome ◽  
Health Care Centre ◽  
Northern India ◽  
Potential Risk Factors ◽  
The Mean ◽  
Vision Defects

Central Serous Chorioretinopathy(CSCR) is predominantly idiopathic and self limiting macular disease . Present study was planned to determine clinical prole and the factors contributing in nal visual outcome in CSCR.. Retrospective observational study was done on 65 eyes of 53 patients over a period of 2 years. Their best corrected visual acuity(BCVA), color vision, metamorphopsia and mean central macular thickness(CMT) at presentation were compared with values at 6 months follow-up. Mean age of patients was 38 years ± 5.43 years. 79.24% patients were males and 77.36% had unilateral involvement. 30.19% patients gave history suggestive of one or more potential risk factors. The mean BCVA improved from 20/80 at presentation to 20/20 and 20/25 in patients with isolated and CSCR with PED respectively at 6 months. The mean CMT reduced signicantly in both isolated CSCR and when associated with PED at 6 months. Color vision defects in 46(70.77%) eyes and metamorphopsia in 49(75.38%) eyes at presentation persisted in 7(10.7%) eyes and 20(30.76%)eyes respectively at 6 months. Final visual outcome signicantly correlated with visual acuity at presentation. CONCLUSION: BCVA at presentation strongly predicts nal visual prognosis. Patients need to be counselled regarding persistence of color vision decits and metamorphopsia.

Visual Outcome in Ocular Sarcoidosis: Retrospective Evaluation of Risk Factors

2011 ◽  
Vol 21 (6) ◽  
pp. 802-810 ◽  
Author(s):  
Elisabetta Miserocchi ◽  
Giulio Modorati ◽  
Federico Di Matteo ◽  
Laura Galli ◽  
Paolo Rama ◽  
...  
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Macular Edema ◽  
Cystoid Macular Edema ◽  
Multivariable Analysis ◽  
Visual Outcome ◽  
Ocular Sarcoidosis ◽  
Poor Visual Outcome ◽  
Posterior Synechia

Purpose. To analyze risk factors associated with poor visual outcome in patients with ocular sarcoidosis. Methods. In this retrospective study, charts of 44 patients with uveitis and biopsy-proven sarcoidosis were reviewed. Ocular parameters evaluated were as follows: location, type of uveitis, visual acuity, presence of posterior synechia, iris nodules, vitritis, snowballs, chorioretinal lesions, retinal vasculitis, papillitis, macular edema, cataract, and glaucoma. Final visual acuity of the worst-seeing eye at last follow-up was the outcome considered in univariable and multivariable analyses. Visual acuity of the worst-seeing eye was stratified into 2 categories according to the threshold 20/50 (≤20/50 and >20/50). Results. A total of 44 patients with bilateral uveitis were studied. The majority of patients presented with panuveitis (52%), granulomatous type (61%), posterior synechia (62%). The most frequent vision-threatening complications were cystoid macular edema (56%) and cataract (56%). The median best-corrected visual acuity in the worst-seeing eye at presentation and at end of follow-up was respectively 0.4 (interquartile range [IQR] 0.26–0.80) and 0.63 (IQR 0.36–1.00). At univariable analysis, the presence of iris nodules (p=0.049), cystoid macular edema (p=0.007), and cataract (p=0.007) were clinically significant conditions for a visual outcome of 20/50 or worse in the worst-seeing eye. In multivariable analysis, cystoid macular edema (p=0.034) was the only statistically significant predictor associated with unfavorable visual outcome. Conclusions. In this study, we attempted to find risk factors related to poor visual outcome in patients with ocular sarcoidosis. The results suggest that only the presence of cystoid macular edema was significantly associated with worst visual outcome.

scholarly journals Risk factors and visual outcome of Non-Arteritic Ischemic Optic Neuropathy (NAION): Experience of a tertiary center in Kuwait

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247126
Author(s):  
Raed Behbehani ◽  
Abdullah Ali ◽  
Ashref Al-Moosa
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Optic Neuropathy ◽  
Odds Ratio ◽  
Visual Outcome ◽  
Vascular Risk Factors ◽  
Ischemic Optic Neuropathy ◽  
Vascular Risk ◽  
Better Than ◽  
Cup To Disc Ratio

Background Non-arteritic ischemic optic neuropathy (NAION) is the most common acute optic neuropathy over the age of 50 years. NAION is commonly associated with systemic vascular risk factors (diabetes, hypertension, hyperlipidemia) and small cup-to-disc-ratio. We have assessed the prevalence risk factors of NAION and the visual outcome in patients referred to a tertiary ophthalmology center in Kuwait. Materials and methods A retrospective review of new cases of NAION presenting within 2 weeks of onset were included and baseline clinical and demographics characteristic were determined. The prevalence of risk factors and the visual outcome (change in logMAR visual acuity, mean deviation of visual field) was compared between young NAION patients (below 50 years of age) and older NAION patients (over 50 years of age). The odds ratio of a final favorable visual outcome (visual acuity 20/40 or better) by age category was determined. Results Seventy-eight eyes of 78 patients with recent onset NAION were included in the study. The most prevalent risk factors for NAION in our subjects were diabetes (64.1%), small cup-to-disc ratio (61.5%), hyperlipidemia (51.3%) and hypertension (38.5%). Young NAION patients had better final logMAR visual acuity (0.55 +- 0.57) then older NAION patients (0.9 +- 0.73), (p = 0.03). Furthermore, young NAION patients were 2.8 times more likely to have a final visual acuity of 20/40 or better than older NAION patients, odds ratio (OR), 2.87; 95% confidence interval (CI), 1.12–7.40, Chi-square p-value = 0.03). Conclusion There is a high prevalence of systemic vascular risk factors and small cup-to-disc ratio in NAION patients referred to our center across different age groups (below and above 50 years). Patients below the age of 50 years with NAION are more likely to have a final visual acuity of 20/40 or better than NAION patients above the age of 50 years.

Clinical characteristics and risk factors of arrhythmia during follow‐up of patients with idiopathic ventricular fibrillation

2020 ◽  
Vol 31 (10) ◽  
pp. 2677-2686
Author(s):  
Niels K. Stampe ◽  
Camilla B. Jespersen ◽  
Charlotte Glinge ◽  
Henning Bundgaard ◽  
Jacob Tfelt‐Hansen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ventricular Fibrillation ◽  
Clinical Characteristics ◽  
Idiopathic Ventricular Fibrillation

scholarly journals Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry

2009 ◽  
Vol 31 (2) ◽  
pp. 196-202 ◽  
Author(s):  
S. Philipp ◽  
D. Bose ◽  
W. Wijns ◽  
S. P. Marso ◽  
R. S. Schwartz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systemic Risk ◽  
Virtual Histology ◽  
Systemic Risk Factors

Risk Factors for Redetachment and Worse Visual Outcome after Silicone Oil Removal in Eyes with Complicated Retinal Detachment

2007 ◽  
Vol 17 (4) ◽  
pp. 627-637 ◽  
Author(s):  
F. Goezinne ◽  
E.C. La Heij ◽  
T.T.J.M. Berendschot ◽  
A.T.A. Liem ◽  
F. Hendrikse
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Retinal Detachment ◽  
Silicone Oil ◽  
Surgical Techniques ◽  
Visual Outcome ◽  
Oil Removal ◽  
Silicone Oil Removal ◽  
Male Sex ◽  
Anatomic Success

Purpose The goal of this study was to identify risk factors for redetachment and/or a worse visual outcome after silicone oil removal (SOR) for complicated retinal detachment. Methods The authors retrospectively analyzed 287 consecutive eyes with SOR between January 1999 and December 2003. Results Anatomic success after SOR was achieved in 81% of the eyes. The overall anatomic success at the end of follow-up was 94%. Postoperative ocular hypertension was found in 8% of the eyes, hypotony in 6% of the eyes, and keratopathy in 29% of the eyes. After SOR 43% of the eyes had an improvement in visual acuity of at least two Snellen lines. After multivariate analysis, male sex, the presence of preoperative rubeosis, and proliferative diabetic retinopathy (PDR) were found to be risk factors for recurrent retinal detachment. Male sex, preoperative visual acuity of <0.1 Snellen lines, PDR, the performance of three more operations, any size of retinectomy, and hypotony were found to be associated with a poor visual outcome of Snellen visual acuity <0.1. Conclusions Retinal detachment after SOR in the current unselected series of eyes occurred in approximately 20%, which is comparable to the Silicone Oil Study reports, published approximately 20 years ago. However, preoperative selection was then made, and less than 50% of the silicone oil-filled eyes had SOR. The higher overall anatomic success in the current study may be due to improved vitreoretinal surgical techniques.

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