CLINICAL AND LABORATORY PROFILE OF SNAKE BITE ENVENOMATION: A CROSSSECTIONAL OBSERVATIONAL STUDY AT A TERTIARY CARE CENTER

INTRODUCTION: The World Health Organization defines acute flaccid paralysis syndrome as rapid onset of weakness of an individual's extremities, often including weakness of the muscles of respiration and swallowing, progressing to maximum severity within 1 to 10 days. We carried out this observational study in a tertiary care center in North India with the aim of determining the etiology and outcome of Acute Flaccid Paralysis in adults. METHODS: In this observational study, all cases diagnosed with Acute flaccid paralysis admitted to the tertiary care center from 1st January 2015 till 30th June 2016 were enrolled. Ninety-seven consecutive patients of age above 18 years presenting with weakness of duration less than two weeks were enrolled after obtaining informed consent and various investigations were studied. RESULTS: The study analyzed data of 97 patients presenting with flaccid paralysis. They were analyzed for the demographic data, clinical features, investigations, electrophysiological data, and results of the treatment. The most common etiology of acute flaccid paralysis in this entire population was GBS, which was responsible for 50.5% of the cases, followed by the Hypokalemic paralysis (25.8%) followed by neuroparalytic snake bite (15.5%).In this study, 48% of patients with hypokalemic paralysis had a secondary cause for their condition. Primary hypokalemic periodic paralysis occurred in 52% of patients. CONCLUSIONS: In this observational study, GBS was found to be the most common cause for Acute Flaccid Paralysis followed by Neuroparalytic snake bite. Respiratory paralysis was an important risk factor associated with mortality.

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The paradigmatic shift in the clinical profile of dengue patients: a prospective observational study from a tertiary care center in north India

International Journal of Medical Research and Review ◽

10.17511/ijmrr.2020.i02.10 ◽

2020 ◽

Vol 8 (2) ◽

pp. 201-206

Author(s):

Dr. Bajrang Lal Banthia ◽

◽

Dr. Prashant Dubey ◽

Dr. Siddharth Arya ◽

Dr. Sandeep Kumar Rao ◽

...

Keyword(s):

Observational Study ◽

Prospective Observational Study ◽

Care Center ◽

Tertiary Care ◽

Clinical Profile ◽

North India ◽

Tertiary Care Center ◽

Paradigmatic Shift

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Metabolic syndrome in alopecia areata: an observational study at a tertiary care center

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20213338 ◽

2021 ◽

Vol 7 (5) ◽

pp. 647

Author(s):

Subrata Kumar Das ◽

Saptadipa Das

Keyword(s):

Metabolic Syndrome ◽

Observational Study ◽

Alopecia Areata ◽

Care Center ◽

Tertiary Care ◽

Age Group ◽

Tertiary Care Center ◽

Cross Sectional ◽

Laboratory Parameters ◽

Number Of Patients

Background: The aim was to evaluate the parameters of metabolic syndrome (MS) in patients of alopecia areata and to investigate the possibility of an existing relationship between MS and alopecia areata (AA).Methods: This cross-sectional observational study included 50 patients with AA who attended OPD of department of dermatology at a tertiary care center during a period of 1 year. Clinical and laboratory parameters were noted in each patient.Results: This study included 50 patients with AA (33 males and 17 females). In the present study maximum number of patients belonged to the age group 20-30 years with 23 patients, followed by 30-40 years with 17 patients. Most of the study subjects, 17 were college students and number of employees were 15. Out of 50 patients 44 had patch(es) and 2 patient had alopecia totalis. In this study out of 50 patients, 38 had mild AA, 7 had AA and 5 patients had severe AA. No significant derangement of clinical and laboratory parameters of MS observed in patients of AA.Conclusions: In the present study we did not observe any significant derangement of clinical and laboratory parameters of MS in patients of alopecia areata.

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