scholarly journals Metabolic syndrome in alopecia areata: an observational study at a tertiary care center

Author(s):  
Subrata Kumar Das ◽  
Saptadipa Das

<p class="abstract"><strong>Background:</strong> The aim was to evaluate the parameters of metabolic syndrome (MS) in patients of alopecia areata and to investigate the possibility of an existing relationship between MS and alopecia areata (AA).</p><p class="abstract"><strong>Methods:</strong> This cross-sectional observational study included 50 patients with AA who attended OPD of department of dermatology at a tertiary care center during a period of 1 year. Clinical and laboratory parameters were noted in each patient.<strong></strong></p><p class="abstract"><strong>Results:</strong> This study included 50 patients with AA (33 males and 17 females). In the present study maximum number of patients belonged to the age group 20-30 years with 23 patients, followed by 30-40 years with 17  patients. Most of the study subjects, 17 were college students and number of employees were 15. Out of 50 patients 44  had patch(es) and 2 patient had alopecia totalis. In this study out of 50 patients, 38 had mild AA, 7 had AA and 5 patients had severe AA. No significant derangement of clinical and laboratory parameters of MS observed in patients of AA.</p><p class="abstract"><strong>Conclusions:</strong> In the present study we did not observe any significant derangement of clinical and laboratory parameters of  MS  in patients of alopecia areata.</p>

Author(s):  
Subrata Kumar Das ◽  
Saptadipa Das

<p class="abstract"><strong>Background: </strong>The aim was to evaluate the parameters of metabolic syndrome in patients of skin tags and to investigate the possibility of an existing relationship between metabolic syndrome and skin tags.</p><p class="abstract"><strong>Methods: </strong>This cross-sectional observational study included 47 patients with skin tags attended Outpatient department (OPD) of Department of Dermatology at a tertiary care center during a period of 1 year. Clinical and laboratory parameters were noted in each patient.</p><p class="abstract"><strong>Results: </strong>This study included 47 patients with skin tags (28 males and 19 females). In the present study maximum number of patients belonged to the age group &gt;40 years with 19 patients, followed by 30-40 years with 13 patient. In this study no. of students were 15, and no of employee were 11. Most patients had skin tags in more than one area, neck and axilla were involved in 9 patients each. In this study out of 47 patients. 11 patients had derangement of clinical and laboratory parameters of metabolic syndrome based on NCEP adult treatment panel III.</p><p class="abstract"><strong>Conclusions:</strong> In the present study we observed significant derangement of clinical and laboratory parameters of metabolic syndrome in patients of skin tags.  </p>


2020 ◽  
Vol 11 (4) ◽  
pp. 53-57
Author(s):  
Ramesh Raj Acharya ◽  
Dipak Kunwar ◽  
Susmita Khadka ◽  
Rajyashree Kunwar ◽  
Adhyashree Karki ◽  
...  

Background: Globally prevalence of metabolic syndrome ranges from 10 to 84%, depending upon sex, age, race, and ethnicity, region and the definition used. There is limited literature in the prevalence of metabolic syndrome in Nepal. One nationwide survey study reported prevalence of metabolic syndrome is 15% and 16% according to ATP III and IDF criteria respectively. Aims and Objectives: The aims and objective of our study is to study the prevalence of metabolic syndrome and its components in tertiary care center. Material and Methods: This was a descriptive cross-sectional study. We used convenient method of sampling and data collection was done in between May 2019 to July 2019. Bivariate and multivariate logistic regression analysis was done for association of metabolic syndrome with different variables. Results: The total of 362 participants was included in the study. Among them 54.4% were 53 years and above and 45.6% were below 53 years of age. Among all participants 25% were diabetic and 55% were hypertensive. Among all participants metabolic syndrome was found in 45.3%. All components of metabolic syndrome were found to be significantly associated with metabolic syndrome both in bivariate and multiple regression analysis. Conclusion: The metabolic syndrome is very prevalent in our population. These findings prompt the concerned authorities to formulate strategies to prevent the risk factors.


2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Sangita Thapa ◽  
Rabindra Jang Rayamajhi

Introduction: As the medical facilities are improving, the life expectancy is increasing which has led to rapid rise in elderly population. The epidemiology of many diseases in elderly has been modified, including calcium imbalance. This study aims to know the prevalence of hypocalcemia in elderly population visiting a tertiary care center of Kathmandu. Methods: A descriptive cross-sectional study was conducted in a tertiary care center of Kathmandu from March to July 2020 after obtaining ethical clearance (Ref: 2003202007). Total 402 participants at or above 60 years of age groups visiting outpatient departments were included in the study by convenience sampling method excluding those under vitamin D and calcium supplements. Serum total calcium level was measured using standard routine method and corrected with albumin. The serum calcium value less than 8 mg/dl was considered as hypocalcemia in accordance with the reference range of our laboratory. Data analysis for calculation of frequency and proportion was done in Statistical Package of Social Sciences. Results: The prevalence of hypocalcaemia in elderly was found to be 97 (24.1%). Out of 286 participants of age group 60-74 years, hypocalcemia was seen in 75 (26.2%) and among 116 participants of age group >74 years, 22 (19%) were hypocalcemic. Among 181 male participants, 44 (24.3%) had hypocalcemia and out of 221 female participants, 53 (24%) had hypocalcemia. Conclusions: The finding of present study suggests that hypocalcemia is common among elderly which can be life threatening. Therefore, regular monitoring of serum calcium is recommended for this age group.


2021 ◽  
Vol 6 (3) ◽  
pp. 57-61
Author(s):  
Varun Jaswal ◽  
Jitender K Mokta ◽  
Vivek Chauhan

Introduction: Systemic Lupus Erythematosus (SLE) is a disease of thousand faces whose manifestations vary with the interplay of genetic, ethnic, and host factors along with environmental exposures and geographical conditions. Since the first case of SLE reported in India in 1955, many case series have been published from various centers depicting Clinical and Immunological features in the Indian population. This study was undertaken to study the clinical and immunological profile in a tertiary care center in the sub-Himalayan region of northern India. Materials and Methods: This study is a cross-sectional retrospective study conducted at a tertiary care center in the hilly northern state of Himachal Pradesh over a period of 1 year; from 1st June 2017 to 31st May 2018. The records of all patients admitted in the study period with the department of medicine and diagnosed with SLICC 2012 classification criteria were studied to abstract the Clinical and Immunological profile of patients. Results: A total of sixty-nine patients were included in the study. 96% of the subjects were female patients, and 84 % of the patients were in the reproductive age group of 20 – 40 years. Mucocutaneous manifestations were most commonly seen in nearly 89 % of patients followed by musculoskeletal involvement in about 71 %. Hematological involvement was more frequent than reported in the literature. Lupus Nephritis was diagnosed in about 30 % of the patients. Fatigue and synovitis were the most common features, followed by oral ulcers and Acute cutaneous lupus. ANA and ds DNA positivity was 98.5 and 72.4 % respectively. Six cases of MCTD were d=found in the study group. Conclusion: In hospitalized SLE patients admitted in a tertiary care center of the northern hilly state, females of reproductive age group constituted the majority of patients. Mucocutaneous, Musculoskeletal, hematological, and renal involvement was most prevalent. Keywords: SLE, cross-sectional study, Mucocutaneous involvement, Renal Biopsy, Hilly area.


2020 ◽  
Vol 19 (1) ◽  
pp. 26-30
Author(s):  
Sagar Mani Jha ◽  
Nabin Bhakta Shakya ◽  
Sunil Shakya ◽  
Manisha Maharjan

Introduction: Leprosy is responsible for disability and deformity among patients. Nerve damage is one of the main features of leprosy and it is the main cause of disability in the patients. Developing deformity leads to restriction in professional work and hence reduced income as well as it also acts adversely on social wellbeing. The aim of this study was to study the spectrum of Grade 2 disability among all leprosy patients attending outpatient and inpatient according to WHO grading and to find the association with Ridley Joplingclassification. Methods: It was an observational cross sectional hospital based study. All the inpatients and outpatients of leprosy getting treatment and were on follow up in the Department of Dermatology between December 2017 to November 2019 were included. Details of disability and deformity were recorded and were Classified as per WHO grading and Ridley Jopling classification. Cross tab was used in descriptive analysis to compare between different variables and data was analysed in percentage. Results: A total of 88 patients were included in the study. Maximum number of patients 41 (46.7%) belonged to 30 to 50 years of age group. Various degrees of loss of sensation was seen in all patients and total number of patients with Grade 1 disability were 68 (77.3%) and Grade 2 disability were 20 (22.7%). Maximum number of patients 11 (12.5%) with Grade 2 disability was seen in Lepromatous Leprosy. Conclusions: Disability and deformity can occur in any spectrum of disease and intervention as early as possible will help reduce the incidence.


2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Ravi Bhandari ◽  
Pravakar Dawadi ◽  
Mohit Thapa Magar ◽  
Ritesh Sinha ◽  
Nirab Kayastha ◽  
...  

Introduction: Implant removal surgery is one of the common surgical procedures done in orthopedics. Studies report that a major portion of orthopedic surgeries carried out in different institutions comprises implant removal procedures. This can be challenging in limited manpower and infrastructure availability scenarios, like in developing countries like Nepal. This study aims to study the prevalence of orthopedic implant removal procedures carried out among overall surgical procedures in the orthopedic department of a tertiary care center in Nepal. Methods: A descriptive cross-sectional study was performed on the medical records of the department of orthopedics of a tertiary care center after approval from the institutional review committee. The data included records from the starting of 2018 to the end of 2019. Data related to the number of implant removal procedures, types of implants, indications, fracture sites, anesthesia use, gender and age distribution were studied. Statistical Package for Social Sciences version 20 was used to study descriptive data. Results: Out of 2557 orthopedic operations carried out in the study duration, 458 (17.91%) of implant removal procedures were done in the department. The most common age group was the young adult age group, 255 (55.68%). Medium-sized implants were the commonly removed ones, 337 (73.58%). Elective procedures were the most common indication, 369 (80.57%). Conclusions: Implant removal procedures cover a major fraction of overall orthopedic operations carried out by the department, most of which are elective procedures. In limited-resource settings, this can be challenging, and a proper evaluation with counseling could be done before implant removal surgery.


2019 ◽  
Vol 6 (9) ◽  
pp. 474-480
Author(s):  
Dr. Chandra Mohan Chekkali ◽  
◽  
Dr. Greeshma Reddy Kankanala ◽  
Dr. Rakesh Kotha ◽  
Dr. Himabindu Singh ◽  
...  

2017 ◽  
Vol 4 (5) ◽  
pp. 1644 ◽  
Author(s):  
Ramesh Choudhary ◽  
Sunil Gothwal ◽  
Swati Nayan ◽  
B. S. Meena

Background: The development in science and technology has helped us to overcome the superstitions associated with pregnancy to some extent. Objective of present study was to record information about common ritualistic myths during pregnancy and after baby birth.Methods: It was a cross sectional observational study conducted in a tertiary care center. Information was collected from 200 admitted women who delivered in last 3 days with direct questions to mother.Results: Total 180 (90%) women were following the ritualistic myths. Mean age and mean parity was 30.1 years and 2.8 respectively. Sixty five percent women were belonging from rural background. Religion distribution was as follows 144 Hindu, 40 Muslim and 16 were others. Prevalence of the myths was 136 (94.4%), 32 (80%), 12 (75%) in Hindu, Muslim and other religions respectively. An inverse relation was observed between education level and acceptance of myth.Conclusions: Ritualistic myths during pregnancy and after birth were more common with low literacy, rural background and in Hindus. 


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