scholarly journals SOME FEATURES OF THE KIDNEY SCAR FORMATION AFTER SURGERY IN THE EXPERIMENT

2021 ◽  
Vol 29 (3) ◽  
pp. 275-284
Author(s):  
I.V. Maiborodin ◽  
◽  
S.V. Marchukov ◽  
V.I. Maiborodina ◽  
◽  
...  
Keyword(s):  
Connective Tissue ◽  
Inflammatory Infiltrate ◽  
Structural Changes ◽  
Left Kidney ◽  
Scar Formation ◽  
Cystic Degeneration ◽  
Tubular Structures ◽  
Vascular Disorders ◽  
Midline Laparotomy ◽  
Kidney Resection

Objective. To study the features of scar formation and structural changes in the remaining renal parenchyma in rats after the kidney resection in various terms. Methods. A layeredclosure of midline laparotomy and the caudal part of the left kidney removal was performed in rats under general inhalation ether anesthesia in a clean operating room. The morphology of the remaining kidney part after resection was studied using light microscope in different terms. Results. Athrombusfrom blood leaking outof the cut vessels is formed on the damaged surface of the kidney immediately after the resection. This clot with the parenchyma is gradually replaced by the connective tissue along the edge of the defect with the subsequently formation of a thin connective or fibrous tissue scar. However, in many cases, the number of which in rats can reach 40%, the processes of kidney damage continue for a long time after surgery, and leading to total or subtotal nephrosclerosis. The detected cystic change in tubular structures, apparently, occurred firstly due to their intersection during the resection, clamping by a blood clot and / or compression by edema distal to the observation site. Then, the forming extensive scar again clamped the adjacent tubular structures with subsequent cystic degeneration and sclerosis. In this case, detritus formed from non-viable renal tissues is eliminated by macrophages, which can form multinucleated cells with fused cytoplasm. Conclusion. Structural changes in the nephrosclerosis progression after kidney resection consist in the gradual replacement of the all renal cortical and medullar parenchyma by the connective tissue. This is not associated with the autoimmune process, but is more likely due to both impaired urine outflow after intercut of the tubular structures at resection and/or compression by edema, inflammatory infiltrate, forming or organizing scar, and vascular disorders associated with these causes. The inflammation accompanying necrosis and sclerosis of the renal structures can become granulomatous. What this paper adds For the first time, it has been shown that the progressively enlarging scar can be formed after the kidney resection, resulting in total nephrosclerosis. Such changes develop both due to the intersection of the tubular structures during the resection and their compression by edema, inflammatory infiltrate, forming or organizing a scar, and vascular disorders due to the above-mentioned causes.

Clinic, prevention and treatment of gonorrhoeal urethral strictures

1934 ◽  
Vol 30 (11-12) ◽  
pp. 1145-1151
Author(s):  
Ya. B. Voitashevsky ◽  
D. I. Tukhshnid
Keyword(s):  
Connective Tissue ◽  
Scar Formation ◽  
Canal Wall ◽  
Residual Urine ◽  
Urethral Strictures ◽  
Prevention And Treatment

By stricture we mean a persistent narrowing of the urethral lumen caused by organic changes in the canal wall with the development of connective tissue and scar formation. According to the origin, strictures are divided into congenital and acquired, and the latter into inflammatory, traumatic and chemical; clinically, they are divided into permeable and impassable and 1) without residual urine and 2) with residual urine; the latter can be: a) with infection and b) without infection. Numerous statistics show that congenital strictures occur in no more than 5%. Among the acquired strictures, gonorrhoeal strictures are on the first place according to their frequency; on the average, they are from 70% to 95%. Traumatic strictures are in the second place - they occur in 3% to 12%. In last place are strictures of chemical origin.

Porudominskie and Herzenberg. Towards the doctrine of the pathological anatomy of male gonorrhea. (Ztsch. F. Urol, No. II, 1936)

1937 ◽  
Vol 33 (7) ◽  
pp. 938-938
Keyword(s):  
Connective Tissue ◽  
Inflammatory Infiltrate ◽  
Squamous Epithelium ◽  
Plasma Cells ◽  
Lymphoid Cells ◽  
Genitourinary Tract ◽  
Columnar Epithelium ◽  
Pathological Anatomy ◽  
Surface Layers

The material of the authors consists of 5 cases of gonorrhea that died from accidental causes, 1 case of amputation and 3 cases. extirpation of the paraurethral course. Conclusions: the gonorrhea process is played out in the epithelium and connective tissue of the genitourinary tract and has an exudative-proliferative character. The inflammatory infiltrate consists of lymphoid cells, plasma cells, leukocytes, and eosinophils. The squamous epithelium is not an obstacle to the penetration of infection this is clearly seen when studying the process in the paraurethral passages. The penetrated deep into the gonococcus are phagocytosed by lecocytes in the surface layers of the submucosa. Metaplasia of columnar epithelium in squamous and transitional, can be in any part of the genitourinary tract and can be detected before the onset of gonorrhea. Litreitis is not necessary for gonorrhea. Prostatitis can be without vesiculitis.

Light and Scanning Electron Microscopy of Human Spinal Ligaments

1985 ◽  
Vol 55 ◽  
Author(s):  
L.-H. Yahia ◽  
G. Drouin ◽  
C.-H. Rivard
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Connective Tissue ◽  
Idiopathic Scoliosis ◽  
Blood Vessels ◽  
Structural Changes ◽  
Loose Connective Tissue ◽  
Morphological Studies ◽  
Spinal Ligaments ◽  
Scanning Electron

ABSTRACTSpinal ligaments were obtained from normal and scoliotic individuals. Detailed morphological studies were carried out on the yellow, interspinous and supraspinous ligaments by light and scanning electron microscopy. Normal yellow ligaments are mostly constituted of dense elastin fibers with only a few collagen fibers and sparse blood vessels, while in normal interspinous and supraspinous ligaments, the presence of collagen is highly dominant. In the latter structures, the collagen fascicles are characterized by a regular waviness morphology. The fibrils constituting the fascicles appear either parallel or helical with respect to the fascicle axis. Structural changes are observed in the spinal ligaments of patients with congenital as well as idiopathic scoliosis. For yellow ligaments, only slight differences are found between normal and scoliotic specimens. However, alterations in collagen waviness and architecture are observed mainly in the supraspinous ligaments and to a lesser extent in the interspinous ligaments. In addition, increases in the cellularity, loose connective tissue and vessels are found in both forgoing ligaments. These results indicate that the more pronounced scoliosis-related changes occur in ligaments having the farthest distance from the axis of flexion-rotation.

Lymphatic Vessels of Healthy and Inflamed Gingiva

1978 ◽  
Vol 57 (7-8) ◽  
pp. 810-817 ◽  
Author(s):  
Sol Bernick ◽  
Daniel A. Grant
Keyword(s):  
Connective Tissue ◽  
Periodontal Ligament ◽  
Inflammatory Infiltrate ◽  
Nonhuman Primates ◽  
Lymphatic Vessels ◽  
Thin Walled

Lymphatic vessels were traced in healthy and early inflamed gingivae of various nonhuman primates. Lymphatic capillaries and primary collecting vessels originated in the connective tissue papillae and stroma near or adjacent to the attachment epithelium. They emptied into thin-walled irregular-shaped collecting vessels that drained into the periodontal ligament. In early inflammation, all the lymphatic vessels of luminal caliber were distended within and/or surrounding the inflammatory infiltrate.

scholarly journals The Features of the Connective Tissue Morphological Change During a Skin Scar Formation After a Cesarean Section

2021 ◽  
Vol 10 (1) ◽  
pp. 49-53
Author(s):  
E. S. Mishina ◽  
M. A. Zatolokina
Keyword(s):  
Connective Tissue ◽  
Cesarean Section ◽  
Morphological Change ◽  
Age Groups ◽  
Scar Formation ◽  
Morphometric Parameters ◽  
Adjacent Area ◽  
Research Goal ◽  
Skin Scar ◽  
Number Of Births

During a skin scar formation morphofunctional change of skin structures takes place. The action of external mechanical factors can lead to prolongation of reparative processes in the scar and to the change in the morphometric parameters of its components.Research goal: to study the features of the skin structural components morphological change in secundipara women during a connective tissue scar formation after a cesarean section.Material and methods. The materials for the study were the fragments of a connective tissue scar with an adjacent area of intact skin taken from 30 women after operative delivery by Caesarean section. On scanning electron microscopy, morphometric parameters were measured, which enabled to assess the cell composition and the changes in the fibrous components of the connective tissue scar.Results. Analyzing the thickness of the fibers in the same age group, the thickening of the fibers was observed in direct proportion to the number of births. Comparing different age groups with the same number of births, the thinning of collagen fibers was observed. The most pronounced changes were observed in women having three or more deliveries.Conclusion. Under the influence of the stretching force in the skin, a structural change of the connective tissue scar occurs. This change is due to the thickening of collagen structures, the decrease in the density of collagen structures location, the increase in the number of lymphocytes and macrophages.

scholarly journals Tissue Response after Subcutaneous Implantation of Different Glass Ionomer-Based Cements

2019 ◽  
Vol 30 (6) ◽  
pp. 599-606
Author(s):  
Carolina Maschietto Pucinelli ◽  
Raquel Assed Bezerra da Silva ◽  
Luã Lopes Borges ◽  
Alberto Tadeu do Nascimento Borges ◽  
Paulo Nelson-Filho ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Inflammatory Infiltrate ◽  
Collagen Fiber ◽  
Fiber Formation ◽  
Tissue Response ◽  
Control Group ◽  
Advanced Stage ◽  
Glass Ionomer ◽  
Granulomatous Tissue ◽  
Subcutaneous Connective Tissue

Abstract The aim of this study was to evaluate the subcutaneous connective tissue response of isogenic mice after implantation of different glass ionomer-based cements (EQUIA® Forte Fil, EQUIA® Fil and Ketac™ Universal Aplicap™). Eighty-seven isogenic BALB/c mice were allocated in 12 groups, 9 were considered as experimental groups (Ketac, E. Fil and E. Forte at 7, 21 and 63 days) and 3 controls (empty polyethylene tubes at 7, 21 and 63 days). After the experimental periods, the subcutaneous connective tissue surrounding the implanted material was removed and subjected to histotechnical processing and staining with hematoxylin and eosin. A histopathological description of the tissue reaction surrounding each material and a semi-quantitative analysis of collagen fiber formation and inflammatory infiltrate were performed. Additionally, the thickness of the granulomatous tissue in contact with each material was measured. Data were analyzed statistically (α=0.05) by the Kruskal-Wallis test, followed by Dunn post-test. Initially, the collagen fiber formation was not different among all the tested materials (p>0.05) but was different at 21 days with the control group presenting the most advanced stage of collagen fiber formation. At 63 days, EQUIA® Forte Fil group showed the most advanced stage of collagen fiber formation, compared to EQUIA® Fil group (p<0.05). The inflammatory infiltrate was not different among the tested materials in any experimental period (p>0.05). The thickness of the granulomatous tissue was greater in the E. Forte group, compared to control in all periods. All glass ionomer-based cements showed tissue compatibility, according to the evaluated parameters.

scholarly journals Morphological and Biochemical Substantiation of Hepatic Changes at Opisthorchosis

2020 ◽  
Vol 14 (1) ◽  
pp. 53-58
Author(s):  
Alevtina A. Sidelnikova
Keyword(s):  
Uric Acid ◽  
Connective Tissue ◽  
Biochemical Parameters ◽  
Structural Changes ◽  
Biochemical Study ◽  
Morphological Changes ◽  
Liver Parenchyma ◽  
Experimental Conditions ◽  
Normal Limits ◽  
Markers Of Inflammation

The purpose of the research is comparing structural changes in the liver of rabbits with biochemical parameters at opisthorchosis under experimental conditions. Materials and methods. Laboratory studies included a biochemical blood test to determine the amount of alanine aminotransferase (ALT), aspartate aminotransferase (AST) as the main markers of inflammation and their ratio, lactate dehydrogenase (LDH (total)), creatine kinase – CPK-MF (muscle), and uric acid. Morphological changes in the liver were determined using light microscopy and analysis of a macroscopic pattern. Histological sections of the liver were stained with hematoxylin and eosin, and according to Van Gieson (to identify the degree of proliferation of connective tissue). Results and discussion. A biochemical study obtained an excess of KFK-MV by 1.93 times, and LDH by 5.4 times in infected animals. The amount of uric acid was within normal limits. AST and ALT were within normal limits, but the ratio confirmed the inflammatory process. Macroscopic examination revealed fibrosis of the edge of the hepatic lobes in the form of a tape. Microscopic examination revealed a sectoral lesion of the liver parenchyma with loss of cytoarchitectonics and proliferation of connective tissue between the lobules. Hepatocytes lying on the periphery of the lobes had more pronounced structural changes compared to the central ones. Segregation of cytoplasmic glycogen granules and nuclear swelling were noted in the cytoplasm of peripherally located hepatocytes. Thus, changes in the liver that occur during opisthorchosis at the cellular and tissue levels are confirmed by an increase in individual biochemical parameters and morphological changes in the liver, as one of the central organs of biochemical processes.

scholarly journals Case Report – Nasolabial Cyst

2020 ◽  
Vol 04 (4) ◽  
pp. 01-02
Author(s):  
Carlos Zappelini
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Operating Room ◽  
Inflammatory Infiltrate ◽  
Squamous Epithelium ◽  
Respiratory Epithelium ◽  
Cystic Structure ◽  
Surrounding Connective Tissue

Injury excision in the operating room under general anestesia (figure 1). The anatomopathological examination showed a coated uniloculated cystic structure, sometimes by respiratory epithelium, sometimes by squamous epithelium. Surrounding connective tissue with a hyalinization band and scarce monomorphonuclear inflammatory infiltrate, corresponding to nasolabial cyst. The patient is undergoing postoperative follow-up, without recurrence

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