Comparison between Low Level Diode Laser Therapy and Acyclovir Cream 5% in Treatment of Herpes Labialis

Author(s):  
Parisa Hajian ◽  
Amir Mansour Shirani ◽  
Maryam Khosravi

Introduction: Recurrent Herpes Labialis (RHL) is a common infection and occurs in 20 to 40% of the general population. Risk for transmission exists in dental treatments. There are several different treatments for it. The purpose of this study is a comparison between low-level Laser therapy (LLLT) and acyclovir cream for the treatment of it. Materials & Methods: This performed study was a semi-blind clinical trial in the Oral Medicine Department, Dental School, Islamic Azad University Isfahan Branch (Khorasgan) in the year 2015- 2016. 30 patients got divided into 2 similar groups. Patients in LLLT group, treated in 3 sessions every other day, received 660 nm laser irradiation,100mW,4 J/cm2, continuous, located at a distance of 1 mm from the lesion for 40 seconds. Patients in the medication group treated with 5% acyclovir cream five times a day. In both groups severity of pain and lesion size during treatment and healing time recorded. The collected data were analyzed using statistical tests including independent T-test and Repeated Measures ANOVA ( p value < 0.05). Results: The laser group had better statistically findings for the median time for pain relief (p value < 0.001), and the median time for healing (p value < 0.001), the median lesions size two days after treatment (p value = 0.03), and four days after treatment (p value = 0.003). Conclusion: According to data analysis, laser 660 nm is more effective in pain relief and lesions size reduction and healing time than topical acyclovir in patients with herpes labialis.

2013 ◽  
Vol 1 (2) ◽  
pp. 76-81 ◽  
Author(s):  
Masoume Masoumipoor ◽  
Seyed Behnam Jameie ◽  
Atusa Janzadeh ◽  
Farinaz Nasirinezhad ◽  
Mahdie Kerdari ◽  
...  

Author(s):  
Amir Hossein Mirhashemi ◽  
Leila Jazi ◽  
Aryan Hesamarefi

Introduction: Pain control in patients undergoing orthodontic treatment is one of the major challenges of such treatments. The use of new technologies such as Laser offers promising results in this field. The goal of this study is to survey the works on effect of low-power laser on pain relief during orthodontic treatments. Methodology: The key terms including “orthodontics, reduction, pain, low level, power, laser and laser therapy” alone as well as combinations. those key terms were used to search the databases including “Google Scholar, Science Direct, and PubMed”. The review of collected sources was done which led to selection of 557 papers. The validation was done through CONSORT guidelines. Results: After review of selected papers, 34 studies including 32 human studies and 2 animal studies were selected. Conclusion: The positive findings of reviewed studies on use of laser therapy suggest that low power laser could be effective on pain relief. Conducting further studies on this subject will be beneficial.


2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Emma Jane Suiter

Clinical bottom line Category of research question Treatment The number and type of study designs reviewed Five papers were critically reviewed. Four were randomised controlled trials and one was a case report Strength of evidence Moderate Outcomes reported Three out of the five studies currently available assessing low level laser therapy to improve wound healing, suggest that low level laser therapy has no beneficial effect on the healing of open or incisional wounds. Of the papers that used statistical analysis, no statistical significance was found in wound surface area over time or tissue histological findings between wounds treated with laser therapy and those who were not. Two papers identified did find decreased wound healing times however the strength of evidence is far poorer for both, with only subjective assessment of the wound in the controlled trial and the other being a case report without control Conclusion Currently there is no strong evidence that low level laser therapy increases the speed of wound contracture and reduced healing time. More studies are recommended to provide stronger evidence towards the use of low level laser therapy in wound healing, preferably with a larger population of dogs and with laser settings which are consistent with previous studies for comparison How to apply this evidence in practice The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources. Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.   


2012 ◽  
Vol 21 (23-24) ◽  
pp. 3513-3522 ◽  
Author(s):  
Jaqueline de O Santos ◽  
Sonia MJV de Oliveira ◽  
Flora MB da Silva ◽  
Moacyr RC Nobre ◽  
Ruth H Osava ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
pp. 14-19
Author(s):  
Dadollah Shahimoridi ◽  
Seyed Ali Shafiei ◽  
Bahram Yousefian

Introduction: This study assessed the effect of polarized low-level laser therapy (PLLLT) on the treatment of myofascial trigger points (MTrPs) in the trapezius muscles. Its effectiveness in pain reduction was compared to low-level laser therapy (LLLT). Methods: Sixty-four patients with MTrPs were randomly divided into 2 groups, namely PLLLT and LLLT. Each patient received treatment for a period of 2 weeks, 5 sessions a week. The intensity of laser irradiation to the skin surface was 6 J/cm2 . The system exit power was 160 mw at a 755 nm wavelength. The visual analog scale (VAS) for the 1st, 5th and 10th sessions was analyzed through two-way repeated measures ANOVA. Results: Increasing the number of treatment sessions was effective in reducing pain intensity (P>0.05). The effect of LLLT on pain reduction was significantly greater than that of PLLLT (P>0.05). Referred pain (RP), the limitation of neck movement (LNM), the presence of muscular taut band (PMTB) and the sensitivity of muscular taut band (SMTB) were reduced significantly by the end of the 10th session, compared with participants’ condition at the beginning of the 1st session in both groups. Conclusion: PLLLT and LLLT can effectively treat MTrPs in the trapezius muscles and they reduce RP, LNM, PMTB, and SMTB in particular. However, the effect of the LLLT was significantly greater than that of PLLLT. In accordance with the observed results, LLLT is recommended as an effective method for treating MTrPs.


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